Gene ILK (Mouse)

ILK

Species: Mouse
Alias: Taf10, ILK
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: ILK

Sequence

Name Sequence Type Origin Length Description Download
ILK.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 257 Kinase domain by global Sugen HMM Fasta, JSON
ILK.NA RNA Sugen 1797 None Fasta, JSON
ILK.AA Protein Sugen 452 None Fasta, JSON

Protein domain

Protein domains of ILK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ank ILK.AA Ank 66-98 48 3.8e-10 40.87 Pfam 1-33 (33) Show / Hide 
Range on Protein: 66-98
Range on HMM: 1-33/33
Sequence Identity: 48% (16 aa)

GDDTPLHLAASHGHRDIVQKLLQYKADINAVNE
  .||||||...|| ..|. |||. ||.||.. 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ILK.AA Ank 33-65 48 2.8e-09 37.75 Pfam 1-33 (33) Show / Hide 
Range on Protein: 33-65
Range on HMM: 1-33/33
Sequence Identity: 48% (16 aa)

HGFSPLHWACREGRSAVVEMLIMRGARINVMNR
.||.|||.||| |.  ||.||. .|| .|. ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ILK.AA Ank 99-131 36 5.5e-08 33.07 Pfam 1-33 (33) Show / Hide 
Range on Protein: 99-131
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

HGNVPLHYACFWGQDQVAEDLVANGALVSICNK
.|. |||.||..|. .|...|. .|| | . ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Kinase ILK.AA ILK 193-445 74 7.1e-233 779.92 In-house 1-253 (253) Show / Hide 
Range on Protein: 193-445
Range on HMM: 1-253/253
Sequence Identity: 74% (189 aa)

LNFLAKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQAPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQS
||...|.||.||||.|.|||||||||.|.||||.|.||.|||||||.||||||||||..||||.|..||||....|..|||.||||.||||.|..|||..
LNLHTKINESHSGEMWRGRWQGNDIVAKILKVRQWTTRISRDFNEEFPRLRIFSHPNICPVLGCCNQPPAPNLVIISQWMPHGSLYHVLHEATGVVVDHG

QAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPF
|.|.||||.||||.|||...|.|||..|||..|||||||||||.|.|.||||||.||||.|||.||||||.||||.|.||.||||||.|.||||||||||
QMVSFALDIARGMSFLHSMDPMIPRYYLNSHHVMIDEDMTARINMGDTKFSFQCRGRMYQPAWMAPEALQRKPEDMNWRSCDMWSFAILIWELVTREVPF

ADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPI
||.|.||.|||.||||||..||||||||.||||||||||||.||||||||.||
ADWSPMECGMKIALEGLRVHIPPGISPHMCKLMKICMNEDPGKRPKFDMIIPI
Kinase ILK.AA MLK 193-446 34 6.7e-128 431.21 In-house 1-291 (291) Show / Hide 
Range on Protein: 193-446
Range on HMM: 1-291/291
Sequence Identity: 34% (101 aa)

LNFLAKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRK---------SRDFNEECPRLRIFSHPN----VLPVLGACQAPPAPHPTLITHWMPYGSLYN
..|. .... ..|. |||||...|||.|...|. . .|.         ..||..||..|||.||||    . ...|.|. || .|  ........|||||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVMEYCEGGSLYN

VLHEGTN------------FVVDQSQAVKFALDMARGMAFLHTLEP-LIPRHALNSRSVMIDE------DMTARISMADVKFSFQCP-----GRMYAPAW
|||....            .|.| ..|...||..||||..|| ..| .|... |.|. ..|||      ..|..|...........      .... .||
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

VAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFA-DLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPIL
 |||..|....... ...|.||..|.|||..|||||.. ....|.|...||..||||.||.....| .||||.|.|.||.|||.|..||..|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase ILK.AA TKL 199-446 23 2.1e-71 243.56 In-house 1-364 (364) Show / Hide 
Range on Protein: 199-446
Range on HMM: 1-364/364
Sequence Identity: 23% (89 aa)

LNENHSGELWKGRWQG----------NDIVVKVLKVR--DWSTRKSRD---------------------FNEECPRLRIFS--HPNVLPVLGACQAPPA-
. . ..|| .||.|.|          .|..||..|..  | .|..|..                     | ||   . . .  |||... .|.|..||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

----------PHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLE------PLIPRHALNSRSVMIDEDMT--------------
          ... ... ..| |||...||         .| ...|||.||||..||. .      | |    |.|. ...||..|              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

ARIS-MADVKFSFQCPG-----------------------RMYAPAWVAPEALQKKPEDTNR-------------RSADMWSFAVLLWELVTREVPFADL
. |. .   .| .|  .                       .   |.| |||.|......|.               ..|..||...|||..||..|..|.
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

SNMEIG---------MKVALEGLRPTIP------------PGISPHVCKLMKICMNEDPAKRPKFDMIVPIL
 .|..          |.|...||||.||            | . |...|||. |...|| ||| |. |. .|
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase ILK.AA DRK 353-448 36 2.8e-25 82.61 In-house 166-258 (258) Show / Hide 
Range on Protein: 353-448
Range on HMM: 166-258/258
Sequence Identity: 36% (35 aa)

PAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEK
| |.||| |    ..     || .|||. |||.|||. |..    . . . |  .|.|| .|.  .|   .||. | ||||  || .. ....|| 
PCWTAPEVLR---NQRYTEKADVYSFAIVLWECVTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase ILK.AA TKL-Unique 195-336 28 2.9e-23 79.02 In-house 1-159 (290) Show / Hide 
Range on Protein: 195-336
Range on HMM: 1-159/290
Sequence Identity: 28% (45 aa)

FLAKLNENHSGELWKGRWQGNDIVVKVLKV-RDWSTRKSRDFNEECPRLRIFS-HPNVLPVLGACQ--APPAPHPTLITHWMPYGSLYNVLHE-------
|..|. |. .|.  || | | .. .|....  | | .....|..|   .  .  |||..   |.|    ...|.  ...  .| ||||.|||        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-GTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDED-----MTARIS
   |   . .| ||.|.|.|.|| .||..|| |   .| |... .|..     . ..|.
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKIC
Kinase ILK.AA Dicty4 353-448 34 5.7e-21 66.84 In-house 181-277 (277) Show / Hide 
Range on Protein: 353-448
Range on HMM: 181-277/277
Sequence Identity: 34% (34 aa)

PAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFA--DLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPI--LEK
|.|.||| ....| .    .||  ||. .|||..||. |..    . |...  |. ..||| ||.  .|   .|.. | ..|| .|| |  |...  || 
PCWMAPEVMMHQPYNE---KADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase ILK.AA Dicty4-Unclassified 353-446 32 1.5e-20 67.11 In-house 172-263 (263) Show / Hide 
Range on Protein: 353-446
Range on HMM: 172-263/263
Sequence Identity: 32% (31 aa)

PAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLS-NMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPIL
|.| .|| |           .| .|.|..|.||.| . |. .    |...  |.  .||| ||  . . . || | |. .|| ||| .. |.  |
PKWESPECLM---HESYNQKSDVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase ILK.AA TKL-Unique 353-446 29 3.6e-20 67.96 In-house 190-290 (290) Show / Hide 
Range on Protein: 353-446
Range on HMM: 190-290/290
Sequence Identity: 29% (30 aa)

PAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREV------PFADLSNMEIGMKVAL--EGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVP
. |.||| |     ..  ...| .||.. |||..||..      |. ...  ..  .|.   |..||.||. . .   .|.. | . || .|| || |. 
FRWMAPEVLRMNF-CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIH

IL
 |
RL
Kinase ILK.AA LRRK 353-448 35 5.9e-20 67.27 In-house 243-351 (351) Show / Hide 
Range on Protein: 353-448
Range on HMM: 243-351/351
Sequence Identity: 35% (39 aa)

PAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTRE-VPFADLS-N-----MEIGMKVALEGLRPTIPPG-ISP-----HVCKLMKICMNEDPAKRPKF
| |.||| ...  | .    .|. ||...||||.||.  || ...       ||.  .  .||||||||.    |      ...|.. | ..|| |||.|
PGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHF

DMIVPILEK
  || .|. 
SQIVKRLSQ
Kinase ILK.AA Pkinase_Tyr 355-446 32 8.5e-18 60.89 Pfam 180-270 (270) Show / Hide 
Range on Protein: 355-446
Range on HMM: 180-270/270
Sequence Identity: 32% (31 aa)

WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTRE-VP-FADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPIL
| |||... .         | ||| ||.||..|.   | ....|| |.  ... .| |  .|.. .. . .||| |...||..|| |  |. .|
WMAPECINYGK---FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase ILK.AA TK 355-446 22 5e-17 52.89 In-house 351-486 (486) Show / Hide 
Range on Protein: 355-446
Range on HMM: 351-486/486
Sequence Identity: 22% (30 aa)

WVAPEALQKKP------EDTNRRSADMWSFAVLLWELVTRE-VPFAD-LSN---------MEIGMKVALE-------------GLRPTIPPGIS------
| |||.|...       . .     |.||| ||.||..|.  .|..  .||          |.  ..  .             ..|.  ||. .      
WMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYR

--------PHVCKLMKICMNEDPAKRPKFDMIVPIL
        . .  ||. | ..||..|| |. ..  |
MHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase ILK.AA TKL-ciliate2 355-447 33 3e-16 50.19 In-house 184-273 (273) Show / Hide 
Range on Protein: 355-447
Range on HMM: 184-273/273
Sequence Identity: 33% (31 aa)

WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILE
|.||| ..          ||..|....|||.  || |. . .   .  ||  . ||||||    |    ||. | ...   || |. |.  ||
WMAPEVIKAF---YYTEKADVFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase ILK.AA Dicty4-Unclassified 193-310 27 3.8e-16 51.75 In-house 1-127 (263) Show / Hide 
Range on Protein: 193-310
Range on HMM: 1-127/263
Sequence Identity: 27% (35 aa)

LNFLAKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTR--KSRDFNEECPRLRIFSHPNVLPVLGACQAPPAPHPTL--ITHWMPYGSLYNVLH-----E
.  .  . . |  .  || | | |. || .     . |     ||  |   |   .||| . . |.| .| .   |.  ..  |. | |  | |      
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

GTNFVVDQSQAVKFALDMARGMAFLHT
      |    .|.|.| |.||..|||
QQPIKLDDTLIIKYAFDIAQGMQHLHT
Kinase ILK.AA TyrKc 193-446 23 3.2e-15 23.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 193-446
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

LNFLAKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIF--SHPNVLPVLGACQAP-----PAPHPTLITHWMPYGSLYNVLHEGT
. .. || | . || .||.|   .  ||.||         .|| .|   .. .  .|||..  .|.|  .      .. . ...  ||.|.| . |..  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

NFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALN-------SRSVMIDEDMTARIS---MADVKFSF---------QCP----GRMY-AP-AWVAPEA
.  .  .. ..|... |.||..||           |        | ....|. |..||   ..    .            .    |. .  |  | |||.
PK-LCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LQKKPEDTNRR----SADMWSFAVLLWELVTR-EVPFAD-----LSNMEIGMKVALEGLRPTIPPG--------ISPHVCKLMKICMNEDPAKRPKFDMI
.       | .      | ||| |..||. |. . |  .     .|| |. ..   .| |. .||          .. . ..|| | .|||..|| |  |
I-------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV-IEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

VPIL
. ..
HECF
Kinase ILK.AA TK 193-309 12 4.8e-14 42.73 In-house 1-251 (486) Show / Hide 
Range on Protein: 193-309
Range on HMM: 1-251/486
Sequence Identity: 12% (31 aa)

LNFLAKLNENHSG---ELWKGRWQGN---------------------------DIVVKVLKVR-DWSTRKSRD---------------FNEECPRLR-IF
. .. || | . |   | .||.|.|                            .  ||.||   . | .  .|                .|..  .. ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHPNVLPVLGACQAPPA----------PHPTLITHWMPYGS----LYNVLH--EGTNFV-----------------------------------------
 |||..  .|.|  .            ... ... .||.|.    | . |.   .. .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------VDQSQAVK-------------------FALDMARGMAFLH
           ..... .                    .... |.||..||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLH
Kinase ILK.AA DRK 247-315 36 6e-14 43.67 In-house 56-121 (258) Show / Hide 
Range on Protein: 247-315
Range on HMM: 56-121/258
Sequence Identity: 36% (25 aa)

HPNVLPVLGACQAPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLI
|||.   .|.|  |  | .  ..  || |||||.||.      | .   . ..| |.|| .||  .| |
HPNICQFMGTCNNP--PDICICMEYMPRGSLYNILHD-ESIEMDWPLMKQMMFDCAKGMIYLHCCNPII
Kinase ILK.AA S_TKc 193-446 17 1.4e-12 7.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 193-446
Range on HMM: 1-231/231
Sequence Identity: 17% (49 aa)

LNFLAKLNENHSGELWKGRWQG--NDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQAPPAPHPTLITHWMPY--GSLYNVLHEGTN--
  .| |. .   |. .|.|. .      .|..|         ...  |   |.   |||.   ....|     |  ...  ..   |.|. ....     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--FVVDQSQAVKFALDMARGMAFLHTLEPLIPRHA-LNSRSVMIDEDMTARISMAD----VKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFA
  |. .  .| ...  ........| .   |  |  |    ...||    .|  .|     ..          | ..||| |       .....|.||. 
LRFPFPE-HARFYMYQICCALEYCHSH-GII--HRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL-----GYGKCKCDWWSCG

VLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIV---------PIL
..|.|..... ||    .|.  .|. .           || .. ... |.. ||.|||    .          | .
CILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ILK.AA Pkinase_Tyr 193-309 22 9.1e-12 40.48 Pfam 1-128 (270) Show / Hide 
Range on Protein: 193-309
Range on HMM: 1-128/270
Sequence Identity: 22% (30 aa)

LNFLAKLNENHSGELWKGRWQ------GNDIVVKVLKVRDWSTRK---SRDFNEECPRLRIF-SHPNVLPVLGACQ--APPAPHPTLITHWMPYGSLYNV
. |. || | . || .||.|       . .  ||.|  .. .. .   ..|| .|   .. . .|||..  .|.|     |  .. ...  ||.|.|.. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDY

LHEG--TNFVVDQSQAVKFALDMARGMAFLH
|..    .  .. .. ...... |.||..|.
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLE
Kinase ILK.AA TKL-ciliate2 193-315 30 1.1e-11 34.69 In-house 1-120 (273) Show / Hide 
Range on Protein: 193-315
Range on HMM: 1-120/273
Sequence Identity: 30% (37 aa)

LNFLAKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQAPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQS
|.   |. |   | ..| .|    . ||  |.     .. ||| .||  .    |||.   ||||     |  ..|  .   |||. .| .  .  .   
LEIQNKITEGGYGIIYKAKWREIVVAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTK--IPNFCIIMEYCQRGSLWSLLQN-QDVRLTWE

QAVKFALDMARGMAFLHTLEPLI
   . |||.|||. .||  .| |
DRRRIALDIARGVHYLHSSNPPI
Kinase ILK.AA Pkinase 353-437 20 3.5e-10 37.1 Pfam 175-282 (293) Show / Hide 
Range on Protein: 353-437
Range on HMM: 175-282/293
Sequence Identity: 20% (23 aa)

PAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADL------SNMEIGMKVALEGLRPTIPPGIS-------------------PHVCKLMKI
| ..||| ... ....  ...||||. ..|.|..... || .       . |..  ..    |.  .|  .|                   .  ....| 
PWYMAPEVIRGGQYYG--PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

CMNEDPAKRP
| . ||.|||
CLCKDPKKRP
Kinase ILK.AA LRRK 204-309 16 2.4e-09 29.22 In-house 12-181 (351) Show / Hide 
Range on Protein: 204-309
Range on HMM: 12-181/351
Sequence Identity: 16% (30 aa)

SG-ELWKGRWQG----------------------------NDIVVKVLKV--------------------------------RDWSTRKSRDFNEECPRL
.| .  ...|.|                            ... .|....                                 . ..|. | |  |.  .
FGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRAFREFRHEVWIM

RIFSHPNVLPVLGACQAPPAPHPTLITHWMPYGSLYNVLH---EGT-NFVVDQSQAV-------KFALDMARGMAFLH
. . |||... .| |  |..    ...  .|.|.|| .||   .    |.     |.       | ||. |.||..||
SHLNHPNIVSLKGFCIHPLC----MVMEYAPHGDLYHFLHNKKQDGFHFMK----AHISWMLKLKIALQIAKGMEYLH
Kinase ILK.AA Dicty4 246-310 31 6.1e-08 22.76 In-house 56-130 (277) Show / Hide 
Range on Protein: 246-310
Range on HMM: 56-130/277
Sequence Identity: 31% (24 aa)

SHPNVLPVLGACQ----APPAPHPTLITHWMPYGSLYNVLHE-----GTNFVVDQSQAVK---FALDMARGMAFLHT
.|||..  .|||     .|  . .   |  || |.||..||        .   | .   .    |.| ||||. ||.
RHPNICLFMGACTAPRSHP--GKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC
Kinase ILK.AA Pkinase 208-309 15 1.2e-07 28.15 Pfam 16-125 (293) Show / Hide 
Range on Protein: 208-309
Range on HMM: 16-125/293
Sequence Identity: 15% (18 aa)

WKGRWQGND--IVVKVLKVRDWSTRK-SRDFN--EECPRLRIFSHPNVLPVLGACQAPPAPHPTLITHWMPYG----SLYNVLH--EGTNFVVDQSQAVK
.|....|.    .||..|.|. .  |  ....  | .  .|. .|||..  ..... .. ..  ... ... |    .|. ...  ....|  .  .. .
YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIY--MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKF

FALDMARGMAFLH
... ..||....|
YMYQILRGLEYCH