Gene HUNK (Mouse)
HUNK
Sequence
Protein domains of HUNK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | HUNK.AA | CAMKL | 61-320 | 40 | 5.4e-140 | 449.53 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 61-320 Range on HMM: 1-297/297 Sequence Identity: 40% (121 aa) YLIGSRKLGEGSFAKVREGLH-VLTGEKVAIKVIDKKRAKKDTYVTKN-----------LRREGQIQQMIR---HPNITQLLDILETENS------YYLV | || ||.|||.||. ..| .||||||||.||||....|....|| .||| ||..|.. |||| .|....||.. .||| YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV MELCPGGN--LMHKIYEK----KRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN--NIKLIDFGLSNCAG-I-LGYSDPFSTQCGSPAY ||.|.||. |...| .. .|..| ||||| ||..|||...|. |.||||.| ||.||||.. |||.||||.|| . |. . ..|.||||.| MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY AAPELLAR--K-KYGPKIDVWSIGVNMYAMLTGTLPFTVEP-------FSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALANRW .|||.... | .|||.|.||.|| .|||..|.||| .. . . ..|.. . | . ..| . ...|..|...| |||.|.| . .| MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW L . M |
|||||||||
Kinase | HUNK.AA | HUNK | 61-212 | 69 | 5.1e-121 | 394.37 | In-house | 1-166 (433) | Show / Hide |
Range on Protein: 61-212 Range on HMM: 1-166/433 Sequence Identity: 69% (116 aa) YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKK--RL ||.|. |.|||||||||||.||||||||||||||||..|||.||.||||||.||.||.|||||..|....||.|.||||||.||||.||||..||| || YLLGD-KIGEGSFAKVREGMHVLTGEKVAIKVIDKKKIKKDDYVHKNLRREAQIMQMMRHPNIVRLYEVMETDNNYYLVMEYCPGGDLMHKVCEKKGGRL DEAEARRYIRQLISAVEHLHRAGVVHRDLKIEN--------LLLDEDNNIK-----LIDFGLSNCAG .|..||||||||.|||.|.|..||||||||||| ||||.|.||| .||||||||.| EEGVARRYIRQLVSAVHHMHHHGVVHRDLKIENLETYLSLSLLLDDDHNIKNYVAFIIDFGLSNCCG |
|||||||||
Kinase | HUNK.AA | CAMK | 67-320 | 26 | 1e-117 | 381.06 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 67-320 Range on HMM: 1-425/425 Sequence Identity: 26% (114 aa) KLGEGSFAKVREGLHVLTG------------EKVAIKVIDKKRAKKD------------------------TYVTKNLRREGQIQQM-------IRHPNI .||.|||.||... | .|. .|||||.||||..|.. . ||.||| .| .. ..|||| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI TQLLDILE------------TENS--------YYLVM---ELCPGG----NLMHKIYEK---------------KRLDEAEARRYIRQLISAVEHLHRAG .|... | | . .|.|| |.|.|| | .| |. .|..|.|||||.||..|||...| . IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN VVHRDLKIENLLLDED-----------------NNIKLIDFGLSNCAGILG---------------------YSDPFSTQCGSPAYAA-PELLARKK--- .|||||| ||.|||.. ||||.||||..| . ....|.||.|.|.| ||.| .|. IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN -----------YGPKIDVWSIGVNMYAMLTGTLPFTVEP-----------FSLRALYQKMVDKAMNPLPTQLST-----------------------GAV ||||.|.||.|| .|.||.|..|| . .... |..| . | ..|. . MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK NFLRSLLEPDPVKRPNIQQALANRWL ...|..|..|| ||..|.|.|. |. DLIRKMLQVDPEKRMTIEQCLNHPWM |
|||||||||
Kinase | HUNK.AA | AMPK | 62-320 | 43 | 3.2e-109 | 325.41 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 62-320 Range on HMM: 1-254/254 Sequence Identity: 43% (114 aa) LIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDIL-ETENSYYLVMELCPGGNLMHKIYEKKRLDE | ..|||.| || | | |||||||||...|.. |... | . ..|| .| ...|||.|.|| ... ||. ..||| .|| | | ..||.| YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVER-IQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE AEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKIDVWSIGVNMYAMLTG ||.|.. | ||.|| .|| ..|||||| ||||||...|||. |||||| . . .| |||| |||||. . |.| ||..|.|| || .|||| | REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSN---MMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCG TLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALANRWL .||| . . ..||.| .. ..|. ||. | . ....|..||.|| .|.. . |. YLPF--DDENTPTLYKKIKNGEY-YIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
|||||||||
Kinase | HUNK.AA | S_TKc | 62-320 | 35 | 5.4e-99 | 336.11 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 62-320 Range on HMM: 1-231/231 Sequence Identity: 35% (98 aa) LIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPG--GNLMHKIYEKKR-- ||.|.|.|.||. . |. ||..||||.|. ...||| || .. .|||| .|.|. .. ...|.|||.|.| |.|.. | ...| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG ----LDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGP-KIDVWSIGVN ..| .||.|..|...|.|..|. |..||||| ||.|||| .||..||||. .|.||.| | |||.| .||. |.|.||.|. LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI MYAMLTGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALA-------NRWL .| ||.| || . ....|.. | | .|.| .|. || ||| . .||. |. LYEMLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
Kinase | HUNK.AA | MARK | 61-320 | 39 | 4.3e-98 | 321.22 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 61-320 Range on HMM: 1-262/262 Sequence Identity: 39% (106 aa) YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDT-YVTKNLRREGQIQQMIRHPNITQLLDILE--TENS-YYLVMELCPGGNLMHKIYEK- | .. . .|.||.|||. ..|..||.|||||...|. |.. ||..|| .| ... ||||..|... | ||. ||.||...||.|.. |... YKML-KTIGHGSYAKVKLACHKHTGRKVAIKIYEKF--KLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHP -KRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN--NIKLIDFGLSNCA--GILGYSDPFSTQCGSPAYAAPELLARKKYG-PKIDVWSI || | ||||. ||..|||. .|. ..||||.| ||.|.||.. |||.||||.|.| | . .| ||.|.|.|||.. .|.| ||.|.|| NGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK-----LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSL GVNMYAMLTGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALANRWL || .|.|..|..|| .. ||.|.. . . . |. .|... |....|| ..| .|| |.. . .|. GVVLYFMVCGYFPFDGDTQDYKELYKKIL-RGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
|||||||||
Kinase | HUNK.AA | Pkinase | 62-320 | 31 | 3.5e-88 | 304.08 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 62-320 Range on HMM: 1-293/293 Sequence Identity: 31% (93 aa) LIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGG----NLMHKIY--EK . ||.|.|||..|... |. ||..||.|.|.|...|.. .|. ...| || ....|||| .|.|. |.....|.|||.|.|| |.. | .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KRL--DEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNI----KLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA-RKKYGPKIDVWS ... .| |...|..|.....|..|. |..||||| ||.|.|....| |..||||. .. . . ..| ||.| |.|||.. ...||||.|.|| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS IGVNMYAMLTGTLPFTVE--PFSLRALYQKMVDKAMNPLPTQLS-----------------------TGAVNFLRSLLEPDPVKRPNIQQALANRWL .|. .| ||.| .|| . . . . .|... . . ||. . . . |....|..|| |||...|.| |. CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
|||||||||
Kinase | HUNK.AA | HUNK | 213-320 | 59 | 1.3e-80 | 260.91 | In-house | 321-433 (433) | Show / Hide |
Range on Protein: 213-320 Range on HMM: 321-433/433 Sequence Identity: 59% (67 aa) ILGYSDPFSTQCGSPAYAAPELLAR-KKYGPKIDVWSIGVNMYAMLTGTLPFTVEP--FSLRALYQKMVDKAMNPLPTQLS--TGAVNFLRSLLEPDPVK |.||.|.|.|.||||||||||...| |.||||.||||||||||||||||||||||| |..|.|.||.....||..|.|.. |....|||..||||... IFGYEDFFKTHCGSPAYAAPEIYCRGKDYGPKVDVWSIGVNMYAMLTGTLPFTVEPPEFNMRHLHQKIMKGEMNVHPKQMTHLTDCDMFLRRKLEPDKIQ RPNIQQALANRWL |.|.|.....||. RVNLQNKMDHRWM |
|||||||||
Kinase | HUNK.AA | CAMK1 | 61-263 | 42 | 5.1e-80 | 232.29 | In-house | 1-216 (276) | Show / Hide |
Range on Protein: 61-263 Range on HMM: 1-216/276 Sequence Identity: 42% (93 aa) YLIGSRKLGEGSFAKVREGLHVLT---GEKVAIKVID-KKRAKKDT--YVTKNLRREGQIQQ---MIRHPNITQLLDILETENSYYLVMELCPGGNLMHK | .|. ..|.|.|..|... | | |...|||.|| || ||.. ..|..| .| . | |||| .. .. |..| .||||||. || | .. YEFGK-EIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR IYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLL---DEDNNIK--LIDFGLSNCAGILGYSD-PFSTQCGSPAYAAPELLAR---KKYGP | ||. | .||. ..|..||||..| |.|||||| ||||. ||| || ..||||| |.. . .|.||.| | ||| |.. | |. IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSK---IFDHDENLMKTACGTPGYVAPEVLECKKDKPYDK KIDVWSIGVNMYAMLTGTLPF ..|.||||| | .|.| || ACDMWSIGVITYILLCGYPPF |
|||||||||
Kinase | HUNK.AA | QIK | 61-320 | 36 | 2.9e-77 | 263.0 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 61-320 Range on HMM: 1-272/272 Sequence Identity: 36% (104 aa) YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKR--- | |. | .| | || |. . | | .|||||.||| . .. . .| . || || |..||.|. |....||.. |.|.| |..| . . . .. | YDIE-RTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEE-NLQK-CYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGV -----------------LDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDP-FSTQCGSPAYAAPELLARKK . | |||| |..|||...|. ..|||||| ||.|||.. |||..|||.|| . ... .| ||||.|||||.. |. KMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSN----WFKQGQLLMTWCGSPPYAAPEMFEGKE Y-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALANRWL | |||.|.||.|| .|.. .| ||| . .| | |... .| .|.. . | | || .| .|.| . ||. YDGPKVDIWSMGVVLYVLVCGALPFDGK--TLQNLRQRVLSGKFR-IPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM |
|||||||||
Kinase | HUNK.AA | Ciliate-E2 | 62-320 | 23 | 9.8e-75 | 254.59 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 62-320 Range on HMM: 1-365/365 Sequence Identity: 23% (87 aa) LIGSRKLGEGSFAKVREGLHVLTGEKVAIKV-------------IDKKRAKKDTYVTKNLRREGQIQQMIR-------------------HPNITQLLDI . .|.|.|.|..|... . ......|||. ..| . .. .... |.....| |||| .. . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC LE--TENSYYLVMELCPGGNLMHKIYEK-----------KRLDEAEARRYIRQLIS---------------AVEHLHRAG-VVHRDLKIENLLLDEDNNI . ..|..|||||.| ||.|.. |... |...| |......|... |.|.|| . ..|||.| ||.|. | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLIDFGLS-----------------------NCAGILGYS------DPFSTQCGSPAYAAPELLARKK---------YGPKIDVWSIGVNMYAMLTGTLP |.|||||| . . ||. . | |.||.| | ||| | .|| |. |.|.||.|| .| ||.| .| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FTVEPFSLRALYQKMVDKAMNP-------------LPTQLSTGAVNFLRS----LLEPDPVKRPN-IQQALANRWL | .. |. .| . . ..| . .... .|. || ||.. ..|.| . |. F------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
|||||||||
Kinase | HUNK.AA | MELK | 61-320 | 40 | 1.1e-71 | 244.16 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 61-320 Range on HMM: 1-254/254 Sequence Identity: 40% (107 aa) YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDE | . ..| | ||||. |.||...||||..||.. .| .. | . . .|| .| || ..|||. ...||| ||||... | ...||.| YEV-HDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHD---LPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEE AEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPF--STQCGSPAYAAPELLARKKY-GPKIDVWSIGVNMYAML |.| . ||..||. ..| | ||||| ||||.||| ..||||||| || | | | |||||||||||. |.| | ||||.|. .|... EETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGL--CAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLM TGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALANRWL | ||| . ....|.|.. . | || . . || .| || || ... | |. CGFLPF--DDDNMMIMYKKIMSGCYE-EPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV |
|||||||||
Kinase | HUNK.AA | TSSK | 62-264 | 39 | 4.2e-71 | 232.59 | In-house | 1-230 (289) | Show / Hide |
Range on Protein: 62-264 Range on HMM: 1-230/289 Sequence Identity: 39% (92 aa) LIGSRKLGEGSFAKVREGLHVLTGEK----------------VAIKVIDKKRAKKDTYVTKNLRREGQIQQM-IRHPNITQLLDILETEN-SYYLVMELC .. ..|.|.||.|||... . . | ||||.||.|.|..| |. | | || || . ..|||| |.. ..||.. |.|||.. YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTD-YLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYA PGGNLMHKIYEK------KRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSN-CAGILGYSDPF----STQCGSPAYAAP .| | .| .. ..|.| .||. ||..|||...| .||||||| ||.|||...||||.||| .. .. .... .| ||| ||||| EHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPR--DDPGRCCHLSKTFCGSYAYAAP ELLARKKYGPKI-DVWSIGVNMYAMLTGTLPFT | | ..| || |||| || |.|..|..||. EILRGIPYDPKWYDVWSMGVILYIMVCGCMPFD |
|||||||||
Kinase | HUNK.AA | Pkinase_Tyr | 62-208 | 29 | 3.8e-20 | 68.87 | Pfam | 1-158 (270) | Show / Hide |
Range on Protein: 62-208 Range on HMM: 1-158/270 Sequence Identity: 29% (47 aa) LIGSRKLGEGSFAKVREGLHV----LTGEKVAIKVIDKKRAKKD-TYVTKNLRREGQIQQMI-RHPNITQLLDILE-TENS--YYLVMELCPGGNLMHKI .. .|||||.| .|..| |. .||.|.. | | .. . . || .| . .|||| .|. . . . .|.|||..|.|.| . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL YE----KKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLS . |..|. . . .| .. |.|.. . .|||| | |..|.| .| ||||. RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
|||||||||
Kinase | HUNK.AA | TyrKc | 62-319 | 22 | 4.9e-17 | 52.76 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 62-319 Range on HMM: 1-280/280 Sequence Identity: 22% (66 aa) LIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMI--RHPNITQLLDILETE-------NSYYLVMELCPGGNLMHKI . .||||| | .|..| ..||.|.. . . ..|| .| .. .|||| .|. . .. ...|||..|.|.| . . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL YEKKR-LDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSD------PFSTQC----GSP-----AYAAPELLA .... | .. . | . |.||. ...|||| | |..|.. .| ||||| .|.| |. ||| . RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS----RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN RKKYGPKIDVWSIGVNMYAMLTGTLPFTVEP----FSLRALYQKMVDKAMNPLPTQ--------LSTGAVNFLRSLLEPDPVKRPNIQQALANRW .|. .| |||| || |. ..| . .. | . .... . . | | .. . .. . || .||. .. .. YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |
|||||||||
Kinase | HUNK.AA | CAMK1 | 295-320 | 38 | 1.5e-09 | 23.88 | In-house | 251-276 (276) | Show / Hide |
Range on Protein: 295-320 Range on HMM: 251-276/276 Sequence Identity: 38% (10 aa) NFLRSLLEPDPVKRPNIQQALANRWL .|.. .||.|| ||....|.|. .|. DFIKHMLEVDPKKRYTCEQCLNHPWI |
|||||||||
Kinase | HUNK.AA | TSSK | 297-320 | 33 | 1e-05 | 14.77 | In-house | 266-289 (289) | Show / Hide |
Range on Protein: 297-320 Range on HMM: 266-289/289 Sequence Identity: 33% (8 aa) LRSLLEPDPVKRPNIQQALANRWL .|..|.|.| .||.|.. ... |. IRHMLQPHPCNRPHINEICHHCWM |
|||||||||
Kinase | HUNK.AA | APH | 175-208 | 21 | 0.00053 | 14.53 | Pfam | 165-202 (248) | Show / Hide |
Range on Protein: 175-208 Range on HMM: 165-202/248 Sequence Identity: 21% (8 aa) EHLHRAGVVHRDLKIENLLLD--EDNNIK--LIDFGLS .|.......|.|.. |...| .|.. .||.. . AHWPPPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDA |
|||||||||
UBA_CAMKL | HUNK.AA | UBA_CAMKL | 344-382 | 24 | 1.2e-09 | 32.89 | In-house | 1-41 (41) | Show / Hide |
Range on Protein: 344-382 Range on HMM: 1-41/41 Sequence Identity: 24% (10 aa) SPSVVLHMTEKL-GYKNSDVINTVLSNRA-CHILAIYFLLN .... .| ... |.. ..|.....|.. || |.|.|| DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |