Gene Fused (Mouse)

Fused

Species: Mouse
Alias: 1700112N14Rik, Fused
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: Fused

Sequence

Name Sequence Type Origin Length Description Download
Fused.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 251 Kinase domain by global Sugen HMM Fasta, JSON
Fused.AA Protein Sugen 1316 None Fasta, JSON
Fused.NA RNA Sugen 5234 None Fasta, JSON

Protein domain

Protein domains of Fused.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Fused.AA Fused 4-254 75 2.5e-225 754.85 In-house 1-251 (251) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-251/251
Sequence Identity: 75% (189 aa)

YHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQ
|||.||.|.||||.|||.|.||...|||.|||||.|||.|||.||.||.||||...||.|.||.|||||||||||||||||.||.|.||.|||.||.||.
YHVSEMVGQGSFGCVYKARRKYDSKVVAIKFIPKRGRSDKELKNLRRECEIMRRMHHPHIIHMIDSFETDKEVVVVTDYAEMELHQYLEYDGKMPEEQVR

AIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYTT
.||..|||||||||||||||||||||||||.|...||||||||||.||.||.||||||||||||.||||||.||||.||.||.|||||||.||.|||...
RIACHLVSALYYLHSHRILHRDMKPQNILLDKNMHIKLCDFGFARNMSINTHVLTSIKGTPLYMAPELVEEQPYDHHADMWSLGCILYELMVGQPPFCAN

SIFQLVSLILKDPVRWPSTISSCFKNFLQGLLTKDPRQRLSWPDLLHHPFI
|||.|||.|..|.|.|||||.||..||||||||||||.|.|||.||.|||.
SIFHLVSMIKHDDVKWPSTITSCCRNFLQGLLTKDPRHRISWPQLLCHPFV
Kinase Fused.AA AGC 4-254 23 6.2e-111 287.54 In-house 1-395 (395) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-395/395
Sequence Identity: 23% (93 aa)

YHVLEMIGEGSFGRVYKGRKK------YSAQVVALKFIPKLG---RSEK-ELRNLQRE------------IEIMRGLW----------HPNIVH-MLDSF
...| .||.||||.||  |||       . .. |.| . |     . .| .... ..|             .|.  .           ||.||. .  ||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETDKE--VVVVTDYAE----------G-ELFQILE---DDGKLPEDQVQAIAAQ-------LVSALYYLHS-HRILHRD-MKPQNILLAKGGGIKLCDFG
....   .  | .|..          | |||..|    . |...|.... .||.       .|.|| |||| . | ||| .|| |||| . | |||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FARAMST--------------------------------------------------NTMVLTSIKG--TPLYMSPELVEERPYDHTADLWS--VGCILY
..  . .                                                  ..   ... |  || ||.|| .    |....| ||  .||..|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELAVGTPPFYTTS----------IFQLVSLIL------KDPVRWP----------STISSCFKNFLQGLLTKDPRQRLS----------WPDLLHHPFI
|. .| ||||  .           ...  .|.      ...|..|          . .|.  |.....||.|||..||             ..  ||. 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase Fused.AA ULK 4-254 31 1e-108 367.51 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-329/329
Sequence Identity: 31% (103 aa)

YHVLEMIGEGSFGRVYKGRKKYS----AQVVALKFIPKLGRSEKELRN--------LQREIEIMRGLW--------HPNIVHMLDSFETDKE--VVVVTD
|.. ...|.||||.|||||.| .    ...|| | |.|   ..|.  .        |..||.||. |         ||||| ..| |||...  .  ...
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YAEG-ELFQILEDDGKLPEDQ----------VQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKG------------GGIKLCDFGFARAMSTN-----
| .|  |.|... ..|||||.          .. .  |..... .||.|.| |||.||||||. .|            | .|..|||||. .. .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

TMVLTS----IKGTPLYMSPELVEER----PYD-HTADLWSVGCILYELAVGTPPFYTTSIFQLV-----SL----------ILKDPVRWP-----STIS
 |. ..    ..||||||.|......    ||. ...|.||.|||.||. .| ||||.  .....     .|          | | | ..|      .||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

SCFKNFLQGLLTKDPRQRLSWPDLLHHPFI
. .|......|..|...| ||..|..||..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase Fused.AA Pkinase 4-254 32 1.7e-102 351.62 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-293/293
Sequence Identity: 32% (97 aa)

YHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQR--EIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEG-----ELFQILE--DD
||... ||.||||.|||...| . ..||.| |.| .......... |  ||.||. | ||||| ..|.||..... .|..|.||     .|| ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKL--PEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGI----KLCDFGFARAM-STNTMVLTSIKGTPLYMSPELVE-ERPYDHTADLWSV
|..  .|.... .. |....|.|.||..|.|||.||.|||. . | |    |.||||.|. .   |   .|.. ||| ||.||..   ..|.. .| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCILYELAVGTPPFYTT------SIFQLVSLILKDPVRWPSTIS---------------------SCFKNFLQGLLTKDPRQRLSWPDLLHHPFI
||||||.. | |||.        .  |.. .|.. |.....  .                     . .| |. ..|.||| .|......|.||..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Fused.AA S_TKc 4-254 35 3.3e-102 346.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-231/231
Sequence Identity: 35% (94 aa)

YHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEG---ELFQILEDDGK----
|..|. ||.|.||.|||.|.| . ..||.| |.         ....|||.|..   |||||...|.|.. ... .|..|..|   .||..... |.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDH-TADLWSVGCILYEL
  .|| ... ...|...|| |.|||.|.||| ||.|||| .   ||.||||.|| .       |.. ||| ||.||..   .|..  .| ||.||||||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

AVGTPPFYTTSIFQLVSLILKDPVRWPSTISSCFKNFLQGLLTKDPRQRLSWPDLLH-------HPFI
..| |||.   ....  .|.          |. .|.|....|.|||..|..  ..|.       ||..
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Fused.AA ULK 4-254 29 5.3e-96 325.24 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-324/324
Sequence Identity: 29% (97 aa)

YHVLEMIGEGSFG-RVYKGRKKYS---AQVVALKFIPKLGRSEKELR--------NLQREIEIMRGLW---HPN--IVHMLDSFETD--KEVVVVTDYAE
| . ...|.||||  |||||.| .    |.|| | |.| . ..|...        .|..||.||. |    |||  || ..| |||.  . .  ...| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

G-ELFQILEDDGK---------LPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGG------------IKLCDFGFARAMSTNT---MVLTS
|  |.|... ..|         |.|.... .  |..... .||.| | |||.||||||. .| .            .|..|||||.    |.   .....
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

IK------GTPLYMSPELVEER----PYD-HTADLWSVGCILYELAVGTPPFYTTSIFQLV----SL----------ILKDPVRWP-----STISSCFKN
..      ||||||.|......    ||. . .|.||.|||.||.  | .||..  . ...    .|          | . |...|       ||. .|.
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

FLQGLLTKDPRQRLSWPDLLHHPFI
.....|..|...| ||.....||..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase Fused.AA CAMK 9-254 22 3.7e-89 287.36 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-254
Range on HMM: 1-425/425
Sequence Identity: 22% (97 aa)

MIGEGSFGRVYKGRKKYSA------------QVVALKFIPK--LGR------------------------SEKELRNLQREIEIMRG-------LWHPNI
 .|.|||| |.... | .             | || |.|.|  |                          ..| ..|..||||||.        | ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VHMLDSFET-------------------DKEVVVVT---DYAEG-ELFQ--------------------ILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
..... .|.                   ||... |.   .|..| |||.                    |. ..|...|.... .  |..||. |.||| 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

ILHRDMKPQNILLAKGG----------------G-IKLCDFGFARAMSTN-----------------------TMVLTSIKGTPLYMS-PELVE------
| ||| || |||| . .                . ||..|||||. .  .                       .  ..   ||| ||. ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ERPYDHTADLWSVGCILYELAVGTPPFYTT-------------SIFQLVSLILKDPVRWPST----------------ISSC--------FK
        ...|.  .| ||.|.||| . .|.||||               .. .|   |.|   ..|.                 ||           |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NFLQGLLTKDPRQRLSWPDLLHHPFI
......|..|| .|..  . | ||..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Fused.AA STE 4-254 25 5.6e-80 272.02 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-359/359
Sequence Identity: 25% (94 aa)

YHVLEMIGEGSFGRVYKGRKKY---------------SAQVVALKFIPKLGRS---------------EKELRNLQREIEIMRGLW--HPNIVHMLDSFE
.  .|.||.|.|| |||....                . ...| | ...   .               ..|. ....||.||. .   |||||. .....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TD-------KEVVVVTDYAE-GELFQILE---DDGK-----------LPEDQVQAIAAQLVSA-LYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFAR
 .        |. ..  | . | | .|..     ||           .||.|. .|. |.. . |||||||.| ||| ||.||||     .||||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

AMSTN--------------TMVLT--SIKGTPLYMSPELVEE------RPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVSLIL-------------
 .. .              ||.    .. ||| .|.|| ..        .||  .| ||.|| . |.| | ||. . . ..   .|.             
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---KDPVRWPSTIS-------------------SCFKNFLQGLLTKDPRQRLSWPDLLH--HPFI
   ..| . |...|                   ..||.|..  |.|||..| .  .||.  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase Fused.AA CAMKL 4-254 28 1.9e-76 243.42 In-house 1-297 (297) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-297/297
Sequence Identity: 28% (84 aa)

YHVLEMIGEGSFGRVYKGRK-KYSAQVVALKFIP--KLGRSEKELRN-----------LQREIEIMRGLW---HPNIVHMLDSFETDKE------VVVVT
| ... .|.|||| |  ..  ..  . || |.|   |.   .. ..|           ..|||.||. |    ||||..... .||..       .. |.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

DYAEGE---LFQILEDD----GKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGG--IKLCDFGFARAMSTN----TMVLTSIKGTPLYM
 |..|    ||. ..      |..||.. . .  |.|||..|.|||.| ||| || |||| . |   ||..||||.  .  .       |.   |.| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPELVEE--RPYD-HTADLWSVGCILYELAVGTPPFYTTS---------IFQLVSLILKDPVRWPSTISSCFKNFLQGLLTKDPRQRLSWPDLLHHPFI
.||...   .|||   .| || | ||| . .|. ||   .          . .   ..    . .. .|   .......|...| .| .  ... ||. 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase Fused.AA NEK 4-254 34 5.2e-75 255.52 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-286/286
Sequence Identity: 34% (100 aa)

YHVLEMIGEGSFGRVYKGRKKYSAQV-----VALKFIPKLGR-SEKELRNLQ-REIEIMRGLWHPNIVHMLDSFETDK--EVVVVTDYAE--GELFQI--
| ....||.||||.||| |.|   ..     ...| |  .|. |||| .|.|  |. | . | |||||   |||. ..      | .|.|  | |.|   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-LEDDG----KLPEDQVQAIAAQLVSALYYLHSH-----RILHRDMKPQNILLAKGGG----IKLCDFGFARAMSTNTMVLTS-IKGTPLYMSPELVEER
 ..        ..|.|.  . .|...||.|.|..     .||||| ||||| | | .     .|. ||| .. ....|  ...   ||| |||||.....
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

PYDHTADLWSVGCILYELAVG--TPPFYTT--SIFQLVSLILK--DPVRWPST--ISSCFKNFLQGLLTKDPRQRLSWPDLLHHPFI
||.. .| ||.||.|||..     .||. .  .. .|.  | |  .. . ||.   |.  .|... .|.||| || |  ..| .|||
PYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase Fused.AA STE20 4-254 32 2.1e-72 246.88 In-house 1-288 (288) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-288/288
Sequence Identity: 32% (93 aa)

YHVLEMIGEGSFGRVYKGRKKYSAQV----VALKFIPKLGRSE--KELRNLQREIEIMRGLWHPNIVHMLDSFETD----KEVVVVTDYAEG-ELFQILE
|  || ||.||.| |||...| . ..    || | ..    ..  .|....| || ||. . |||||....|.  |     |  .| .| .|  | .|..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---DDGK------LPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMST----NTM-VLTSIKGTPLYMSPELVEE----
    .||      . |.|. .|  ... .| ||||..| ||| | .|||| . | .||.|||..  ...           .. ||| .|.||....    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-RPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVSLIL--KDPV---RW--PSTISSCFKNFLQGLLTKDPRQRLSWPDLLHHPFI
  .||. .| ||.|  . |.| | ||..  . ..   .|.  . |    .   |.. |..|..|.   |.||| .| .  .||.||||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase Fused.AA Ciliate-E2 4-254 22 1.4e-71 244.11 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

YHVLEMIGEGSFGRVYKGRKKYSAQV------------------VALKFIPKLGRSEKELRNLQREIEIMRGLW----------------HPNIVHMLDS
| ....||.|.|| |||....   .                   |. |.. .   ........ .|| ||| .                 ||||. | ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--TDKEVVVVTDYAEG-ELFQILE------------DDGKLPEDQVQAIAAQLVS---------------ALYYLHSHR-ILHRDMKPQNILLAKGGG
|.  .|. .  |..|..| .||....            | ... | ... | .|...               || ||||   |.||| ||.|||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKLCDFGFAR---------------AMSTNTM-----------------VLTSIKGTPLYMSPELVEERP---------YDHTADLWSVGCILYELAVGT
||..|||...                . ..                   .  .| ||| ||.|| ..  .         ||. .|.||.|.||||.  | 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

PPFYTTSIFQLVSLILKDPVRWP------------------STISSCFKNFLQG----LLTKDPRQRLS-WPDLLHHPFI
|||           |.. ... |                    .|   |....     .| ||| .|.. | ..| ||..
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Fused.AA Pkinase_Tyr 4-193 26 2.1e-19 66.33 Pfam 1-207 (270) Show / Hide 
Range on Protein: 4-193
Range on HMM: 1-207/270
Sequence Identity: 26% (56 aa)

YHVLEMIGEGSFGRVYKGRKK----YSAQVVALKFIPKLGRSEKE--LRNLQREIEIMRGL-WHPNIVHMLDSFE-TDKE--VVVVTDYAEG-ELFQILE
 . ....|||.||.||||. |       . || | . | | ....  .. . ||..||. |  ||||| ..      ..   . .|. |...  |   | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

D----DGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAM-STNTMVLTSIKGTPL---YMSPELVEERPYDHTADLW
.    ...|.  .   ...|  ... ||.|... |||    |.|..... .| |||| ||.. .. .  ... .|..|    |.||   .. . .  | |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SVGCILYEL
| |  ..|.
SFGVLMWEI
Kinase Fused.AA TyrKc 4-254 21 1.3e-15 29.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

YHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGL--WHPNIVHMLDSFETD-------KEVVVVTDYAE-GELFQILED
 . ....||| ||.||||. |   . || | . .       .. . ||..||. |   ||||| ..    ..       . . .|. |.. | | . | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

DGK-LPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTN--------TMVLTSIKGTP--L---YMSPELVEERPYDH
 .. |. ..   .. |  .   ||||... |||    |.|..... .| .||| .|.            . . .. ||.   |    |.||   .. . .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

TADLWSVGCILYELA-VGTPPFYT-----TSIFQLVSLILKDPVRWPSTI----------SSCFKNFLQGLLTKDPRQRLSWPDLLHHPFI
  | || |  ..|.   | .| .       | .... .. .   . .             .  ..   .     || .| .  ..  | ..
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
HEAT Fused.AA HEAT 567-597 29 1.178505 6.13 Pfam 1-31 (31) Show / Hide 
Range on Protein: 567-597
Range on HMM: 1-31/31
Sequence Identity: 29% (9 aa)

LLGKLLAQSDDSEQTFRRDSLMCFAVLCEAV
.|  ||   .|..   |. .. |...||| .
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT Fused.AA HEAT 1114-1141 32 0.440489 7.61 Pfam 4-31 (31) Show / Hide 
Range on Protein: 1114-1141
Range on HMM: 4-31/31
Sequence Identity: 32% (9 aa)

PLRSLLGHSENTVRVRAYGLLGHLLQHS
.| ..| ...  ||  |   ||.|..|.
HLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT Fused.AA HEAT 1154-1184 32 6.2e-05 20.95 Pfam 1-31 (31) Show / Hide 
Range on Protein: 1154-1184
Range on HMM: 1-31/31
Sequence Identity: 32% (10 aa)

LLNLLLLGLGDKDPAVRRSASFAVGNAAYQA
.|..|| .| |.|. ||..|  ..|. . ..
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT Fused.AA HEAT 1194-1224 25 0.000914 16.9 Pfam 1-31 (31) Show / Hide 
Range on Protein: 1194-1224
Range on HMM: 1-31/31
Sequence Identity: 25% (8 aa)

AVPSMTQLLGDAQDGIRRNAASALGNLGPEG
 .| . ..| |  . .|..|...||.| .  
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT Fused.AA HEAT 1238-1265 32 0.05796 10.66 Pfam 4-31 (31) Show / Hide 
Range on Protein: 1238-1265
Range on HMM: 4-31/31
Sequence Identity: 32% (9 aa)

LLEMACGDPQPTVKEAALIALRSLQQES
.|  .. || . |.|||. .| .| . .
HLLKCLNDPDWEVREAACWCLGQLCEHC