Gene ChaK1 (Mouse)
ChaK1
Sequence
Protein domains of ChaK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Ion_trans | ChaK1.AA | Ion_trans | 888-1016 | 11 | 7e-06 | 24.23 | Pfam | 1-115 (199) | Show / Hide |
Range on Protein: 888-1016 Range on HMM: 1-115/199 Sequence Identity: 11% (15 aa) IVIAYIFTYAIEKVREVFMSEAGKISQKIKVWFSDYFNVSDTIAIISFFVGFGLRFGAKWNYINAYDNHVFVAGRLIYCLNIIFWYVR---LLDFLAVNQ . ..... ...| . ... ... | |..|. | ...| ..... ..| .. .. |... | | .| .. . . FDYVFTVWFTFEMILKFWAFGFKF---HPFHYFRDWWNWFDFFVVIPSYIDLIWFFFNWD---------------WFRVLRVFRWL-RVLRPLRLFRRWP Q-AGPY-VMMIGKMVANMFYIVVIMALVLLSFGV ... | |........|........... |.. GWMRTLWVWMLMRSMPSIFNVMLLCFFFWFIFAI |
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| Kinase | ChaK1.AA | ChaK | 1595-1813 | 86 | 1.1e-195 | 656.45 | In-house | 1-219 (219) | Show / Hide |
Range on Protein: 1595-1813 Range on HMM: 1-219/219 Sequence Identity: 86% (189 aa) SMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKVLCTWSEHDILKSGHLYIIKSFLPEVINTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIP |||||||.|.||.|.|||.|||.||||||..| ||||||||||.||.||||||||||..||..||.|||||||||||||||||||||...||||||..|| SMSSWSQRGRCAMIQFLSREEMDGGLRRAMRVQCTWSEHDILKPGHVYIIKSFLPEVVRTWHKIYQEDTVLHLCLREIQQQRAAQKLIYTFNQMKPQTIP YSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPAN |.||||||||.|||||.|||..|.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||.|||||||||| YTPRFLEVFLIYCHSANQWFTIEKCMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEEKQSCDMVFGPAN LGEDAIKNFRAKHHCNSCC ||||||.|||||||||||| LGEDAIRNFRAKHHCNSCC |
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| Kinase | ChaK1.AA | Alpha | 1604-1813 | 35 | 2.3e-137 | 393.49 | In-house | 1-215 (215) | Show / Hide |
Range on Protein: 1604-1813 Range on HMM: 1-215/215 Sequence Identity: 35% (78 aa) LCAKIEFLSKEEMGGGLRRAVKVLCTWSEHDILKSGHLYIIKSFLPEVINTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVF .|.||...|...|.|..|.|... ..|......|..|....||| ..|...|........|.|.|.||..|....|..|..||||||..|.. ....... QCTKIQMSSYPFMEGAMRYAMHAWDCWLHQKMVKKQHKKQWKSF-KYVWHHWIKDVERQMVCHHCVREFNQRLWEQEYTTHFNQMKPQPIKQFVHCYIYE LLYCHSAG-QWFAVEECMTGEFRKYNNNNGDE--IIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQ-GVG-ENLTDPSVIKAEEKRSCDMVFGPANLGED |..||... ....||..|.||..|||||.|.. ....|.....|.||||||..|..|.|.|.||| ||| ..||||..... .|....|.||..|.|.. LIHCHNHNIKYYSVENYMEGEYQKYNNNAGWVDFLTDDNEFNQLMQAFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCP-AKLDQGMKFGDGNCGYE AIKNFRAKH--HCNSCC ....|...| .||..| GMFRFFYTHHVQCNHYC |
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| Kinase | ChaK1.AA | Alpha_kinase | 1596-1813 | 30 | 2.1e-93 | 317.53 | SMART | 1-255 (255) | Show / Hide |
Range on Protein: 1596-1813 Range on HMM: 1-255/255 Sequence Identity: 30% (80 aa) MSSWSQLGLCAKIEFLSKEEMGGGLRRAVKVLCTWSEHDIL-KSGHLYIIKSFLPEVINTW--SSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQ---MK ...|.. .| || . .| . |..|.. . .|.||||... ..|. ...|.|..|...|| .. ..| | ||||||....|...... .||| .. DNKWTCQETCVKI-KEPKPFAKGAMRWCYW-GCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHE-T-LHLCLRDVEMQMMCKHWANEFNQEAQHN P--KSIPYSPRFLEVFL-----LYCHSAGQW----------------FAVEECMTGEFRKYNNNNGDEIIPTNTLE---------EIMLAFSHWTYEYTR | |.| . | .. .|. |... ..| |..|..|.|||.|||||||... ... .. |...||||||||... PCPKKIDFIPCYVFHFPRRIPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTTTSQRRTEMFEYCQAFSHWTYEWSN GELLVLDLQGV----GE--NLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCC ...|| |.||| |. ..||| ....... . ||..|||...|..| ..|.||..| HQMLVCDIQGVIHKNGDLYYYTDPQIHTEDQN---GYGFGMGNLGQEGIEKFFQTHQCNQIC |
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| Kinase | ChaK1.AA | Alpha_kinase | 1615-1813 | 23 | 4.7e-67 | 233.34 | Pfam | 1-225 (225) | Show / Hide |
Range on Protein: 1615-1813
Range on HMM: 1-225/225
Sequence Identity: 23% (55 aa)
EMGGGLRRAVKVLCTWSEHDILKSGHLYIIKSFLPEVINTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKP--KSIPYSPRFLEVFLLYCHSAGQ
. |..| . .. || .. ..... ...| ..... |..... ..... .........|. .|.. |||... ...|....|......|... .
FAQGAMRWCFRMFDTW--DPNWRNNQNCVAKWYKKIK-NYNQKQ-SIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIEFYDCCIVYELEDHN
------------------WFAVEECMTG-EFRKYNNNNG---DEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVG--E---NLTDPSVIKAEEKRS
.. .| ..| ||.||||| | |. ... ....| ||||.||....|...| |.|||| . ||||.. .. ..
KPDCYQGFFSYRTDWGGKYWYMEPYIEGCEFVKYNNNYGWVYDNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTDPQIHTKD-GNY
CDMVF--GPANLGEDAIKNFRA-KHHCNSCC
. |.| |..|||...|..| . .| || .|
E-MDFDEGMGNLGQEGIEKFFQNQHKCNHIC
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| Kinase | ChaK1.AA | Alpha-Unclassified | 1716-1813 | 30 | 1.5e-21 | 66.95 | In-house | 110-215 (215) | Show / Hide |
Range on Protein: 1716-1813 Range on HMM: 110-215/215 Sequence Identity: 30% (34 aa) VEECMTGEFRKYNNNNGDEIIPTNTLEE---IMLAFSHWTYEYTRGELLVLDLQG-VG------ENLTDPSVIKAEEKRSCDMVFG--PANLGEDAIKNF ||. . |||.||.|| | || . | .....||||. | . ..| |||| |. .||| . . . .. | | | . VEPYLIGEFVKYSNNTGKEINFVKWEYEAYQYCCTYQHWTYQWTNHCDIVCDLQGWVDENDKKTWKMTDPQIH------TIRQRYQGFKTNCGMRFIDYW RAKH--HCNSCC . | || | FNNHHVQCNHYC |
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| Kinase | ChaK1.AA | VWL | 1716-1775 | 39 | 6.5e-17 | 47.04 | In-house | 107-167 (206) | Show / Hide |
Range on Protein: 1716-1775 Range on HMM: 107-167/206 Sequence Identity: 39% (24 aa) VEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVG-ENLTDP || . |.. ||||| | . .. . |||| |. |. | ... ||||.. |||| VENYIEGDYQKYNNNAGWCNQTDMEYNQLSQAFSHFTWQYSQGYCMIVDLQGNEDGMLTDP |
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| Kinase | ChaK1.AA | VWL | 1807-1818 | 58 | 0.190659 | 0.18 | In-house | 195-206 (206) | Show / Hide |
Range on Protein: 1807-1818 Range on HMM: 195-206/206 Sequence Identity: 58% (7 aa) HHCNSCCRKLKL | || |.|| | HQCNKYCQKLQL |
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