Gene CaMK2d (Mouse)
CaMK2d
Sequence
Protein domains of CaMK2d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | CaMK2d.AA | CAMK2 | 14-272 | 94 | 4.7e-224 | 750.62 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-259/259 Sequence Identity: 94% (246 aa) YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADA ||||||||||||||||||.|. |||||||||||||||||||||||||||||||.|||||||||||||.|||||||||||||||||||||||||||||||| YQLFEELGKGAFSVVRRCVKKCTGQEYAAKIINTKKLSARDHQKLEREARICRKLKHPNIVRLHDSIQEEGFHYLVFDLVTGGELFEDIVAREYYSEADA SHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPP ||||||||||||||| ||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||| SHCIQQILESVNHCHQNGIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPP FWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWI |||||||||||||||||||.|||||||||||||.|||.||||||.|||||.|||||||| FWDEDQHRLYQQIKAGAYDYPSPEWDTVTPEAKNLINQMLTINPKKRITADEALKHPWI |
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| Kinase | CaMK2d.AA | CAMK1 | 14-272 | 44 | 2.8e-153 | 448.97 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-276/276 Sequence Identity: 44% (123 aa) YQLFEELGKGAFSVVRRCMKIPT---GQEYAAKIIN-TKKLSARDH---QKLEREARICRL---LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIV |....|.|.||||.|..| .. | |..|| |.|. | .. | ..||.| | . ..||||. ... .. . ||| .||||||||. || YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV AREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVK--LADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK---DPYGKPVDMW ...|.| ||.|...|||. |...| .|||||||||||||...|. .. .| .|||||. . .| . ||||| |||| .||.|..||| EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW ACGVILYILLVGYPPFWDED-QHRLYQQIKAGAYDFPSPEWDTVTPE-AKDLINKMLTINPAKRITASEALKHPWI .|||.||||.|||||.||. .. |...|| . |.||||.|| . . |||.|..||. .| ||.|....|.|||| SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | CaMK2d.AA | CAMK | 19-272 | 26 | 4.4e-135 | 438.03 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 19-272
Range on HMM: 1-425/425
Sequence Identity: 26% (112 aa)
ELGKGAFSVVRRCMKIPTG------------QEYAAKIINTKKLS--------------------------ARDHQKLEREARICRL-------LKHPNI
.||.|.|..|..|. . |. |..|.|||..|||. ..| ....|| .|... |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VRLHDSISEEGF-------------------HYLVF---DLVTGGEL----FEDIVAREY---------------YSEADASHCIQQILESVNHCHLNGI
..|.. . . . |.|. ....|||| |. ||.... ..|..|.....||.. |..|| ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDLKPENLLLASKSKG--------------AAVKLADFGLAIEVQGDQ-----------------------QAWFGFAGTPGYLS-PEVLRK------
|||||||||.|| ..... . .|..|||.|....... | | |||.| . ||||..
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
--------DPYGKPVDMWACGVILYILLVGYPPFWDE-------------DQHRLYQQIKAGAYDFPSPE------------WDTVTPE--------AKD
..||...|||.|||||||.|.|||||... ....|...|..| ||||.|. || .. | .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LINKMLTINPAKRITASEALKHPWI
||.|||. .| ||.|....|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | CaMK2d.AA | RAD53 | 14-272 | 35 | 1.2e-113 | 340.03 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-305/305 Sequence Identity: 35% (110 aa) YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLS---ARD---HQKLEREARICRLLKHPNIVRLHDSISE-EGFHYLVFDLVTGGELFEDIVARE | . .|||.|.|..|... . |.| .| |||..||.. .. ...|..| . |.||.|.|..|.. . . |.| |.||||||..||... YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK Y----YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGA---------------AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLR . ..|... |....|. | |||.|||||||| |....... ..|..||||. ..|... . ||| |. |||.. RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLS-KFVGEGSFMKTMCGTPQYVAPEVIT KD---------------PYGKPVDMWACGVILYILLVGYPPFWDE-DQ----HRLYQQIKA-GAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEA . |.| ||.| |.||||.| ||||| |. .| |..||| | | ||.|.|| .. ||||||..||...| ||.|. || SKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA LKHPWI | |||. LNHPWM |
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| Kinase | CaMK2d.AA | CDPK | 14-272 | 40 | 2.5e-112 | 345.79 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-271/271 Sequence Identity: 40% (111 aa) YQLFEELGKGAFSVVRRCMKI-PTGQEY-AAKIINTKKLSARDH-QKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFD--LVTGGELFEDIVAREYY |.. ..||||.|..||.. . |.|| | |||. .... . |.. .| | . | ||||... | ..|.|. ..||||||. |... .. YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF SEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGA----AVKLADFGLAIEVQGD----QQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWAC .| .|. ..||| ||.|| |.||||||||||.|. ||.... .|. |.|.. . ... . ..||| |..||||.| | . .| | | TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC GVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWI ||||||||.|||||. . . ....| | |.| |||| .. ||||||.|||. .| ||..|..||.|||. GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | CaMK2d.AA | S_TKc | 14-272 | 36 | 6.2e-112 | 379.09 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-231/231 Sequence Identity: 36% (101 aa) YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTG--GELFEDIVAREY---- |.. ...|||||..|..| .. ||...| |||. ....|| .|.. .|||||.|.|.. . .. |.|.... | |.||. |. | . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGK-PVDMWACGVIL ..| .| . ..||.. ...|| .||.||||||||.|| . .|..||||| .. | ||| |..|||| .||| ..|.|.||.|| FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL YILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALK-------HPWI |..|.|||||. ........|. .|||||.|.|.|. .|.||.|| |||. |||. YEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | CaMK2d.AA | DCAMKL | 14-272 | 39 | 1.3e-103 | 323.31 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-279/279 Sequence Identity: 39% (110 aa) YQLFEELGKGAFSVVRRCMKIPTG-QEYAAKI-----------------INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTG ||. |.| |.|| | . || ..|| || |. .|. | . | .| ...|||.|..|... . | |||. .|.| YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHM-IDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQG GELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLAS-KSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKP | ||. |. ..| ||. . .. . .. | .|||||.||||||. .. .||.||||| .|.|| . ||| | ||.|.. || GDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK VDMWACGVILYILLVGYPPFWDE--DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWI ||.|| ||||||||.|.||| . || .| || .|...||.|.|| .. |||||..|| .| || ||.. ..|||. VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV |
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| Kinase | CaMK2d.AA | Pkinase | 14-272 | 34 | 4.1e-101 | 347.02 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-293/293 Sequence Identity: 34% (103 aa) YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER--EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG----ELFEDIV--AR |.. . .|.|.|..|..|... ||...| |||. .. . .| . | |..| . |.|||||||.|. ... |.|.... || .||. | .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH EYY--SEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLA-SKSKGAAVKLADFGLAIEV-QGDQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDMWAC . || .. ... |||. ...|| .||.||||||||.|. .| ||..||||| . .. .|.|||.|..|||.| .||..||||.| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVILYILLVGYPPFWDE------DQHRLYQQIKAGAYDFPSPEWDTVT-----------------PEAKDLINKMLTINPAKRITASEALKHPWI |.|||..| |.|||... || ....|. . ..|..|.|... .|.||.|...|. .|.||.|| ..|.|||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | CaMK2d.AA | CAMKL | 14-272 | 34 | 8.6e-96 | 306.18 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-297/297 Sequence Identity: 34% (106 aa) YQLFEELGKGAFSVVRRCMK-IPTGQEYAAKIINTKKLS--------------ARDHQKLEREARICRLLK---HPNIVRLHDSISEEGF------HYLV |.. ..||||.|..|. .. . ||...| |||. ||.. .| ...||..| ..|. ||||..|.. | . . ||| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV FDLVTGGE--LFEDIVAREY----YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIE---V-QGDQQAWFGFAGTPG .. ||| ||. ||.... .| .| . .||.. ||.|| .||||||.||||.|| .. . .|..|||.... . |. | | |.| MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP YLSPEVLRK--DPYG-KPVDMWACGVILYILLVGYPPFWDE--------DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALK | .||.. . .|| ..||.|.|||||| ...|| || |. .. .|| .|. | | .| | | ...||| |||. || ||.|. . .. YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN HPWI ||| HPWM |
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| Kinase | CaMK2d.AA | CAMK-Unique | 14-272 | 25 | 2e-93 | 308.8 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 14-272
Range on HMM: 1-363/363
Sequence Identity: 25% (91 aa)
YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLS-ARDHQ-----------------KLEREARICRLLKHPNIVRLHDS----ISEEG-------
| . . .|.|.|..|..|| . || ..| |... .. . . .| ||.||..| ....||||..| | .
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------FHYLVFDLVTGGELFEDIVA--------------------REYYSE--ADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSK-----
|.| ....||.||. |.. . ..|| .|.. .|..|. |.. | ..|||||||.||... . |
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
--------GAAVKLADFGLAIEVQGDQQA--WFGFAGTPGYLSP--------------EVLRKDPYGKPV----DMWACGVILYILLVGYPPFWDEDQH-
.||.||||. .... . . ||| |..| ||. ..|. .. | |..|||.|..|.|.||| |.
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
-------RLYQQIKAGAY-DFPSPEWDT---VTPEAKDLINKMLTINPAKRITASEALKHPWI
.... |..| | .|... |. ...||||.. . .|. |..|..|.|.|.|.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | CaMK2d.AA | RSK | 16-272 | 33 | 5.3e-89 | 302.0 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 16-272 Range on HMM: 1-278/278 Sequence Identity: 33% (93 aa) LFEE--LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDH-QKLER-EARICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY--- | . .|.|.....|.| |||.|| |... .|. .|. .. . | .| . . ||.||.||.. .|| ||. ... |||||. . ... LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKG-AAVKLADFGLAIE-VQGDQQAWFGFAGTPGYLSPEVLR---KDP-YGKPVDMWACG || .|. . .| | | | ||.|||||||| |....| . . .|| |||.. . . . | | .| |. ||.|. .. ..| .| | | FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG VILYILLVGYPPFWD---EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRIT-----ASEALKHPWI |..| .|.|.||| .... . ..|. | .....|.|.....||||||.|||. .|.||.. |.| ..|||. VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | CaMK2d.AA | Ciliate-E2 | 14-272 | 25 | 7.7e-87 | 294.8 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 14-272
Range on HMM: 1-365/365
Sequence Identity: 25% (96 aa)
YQLFEELGKGAFSVVRRCMKIPTG-----------------------QEYAAKIINTKKLSARDH-QKLEREAR----------ICRLLKHPNIVRLHDS
| . . .|.|.|..|..| .. .. ..|| ||.. ... . ... || . |...|.||||......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC
IS--EEGFHYLVFDLVTGGELFEDIV------------AREYYSEADASHCIQQILE---------------SVNHCHLNG-IVHRDLKPENLLLASKSK
. |||.... ||.||. | . .|..| ... ..|||. ....| .. |.|||.||||.|.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----
GAAVKLADFGLAIEVQGD-------------------------------QQAWFGFAGTPGYLSPEVLRKDP---------YGKPVDMWACGVILYILLV
.|..||||. ... | |. . ..|||||..||.|.. . |.. .|.|..|||||..|
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF
GYPPFWDEDQHRLYQQIKAGAYDFPSPE--------------WDTVTPEAKDLINK----MLTINPAKRIT-ASEALKHPWI
|.||| .|||| . .|||.|| |. ...|.||||.| || .| |||| ....|.|||.
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | CaMK2d.AA | TyrKc | 14-272 | 21 | 4.6e-14 | 4.69 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-280/280 Sequence Identity: 21% (62 aa) YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL--KHPNIVRLHDSISEE-------GFHYLVFDLVTGGELFEDIVA .| ..|| ||| .|.... . .. | | .. . .. . ||||| . | .|||||||. .... . ...|. .. .| | . . . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK REY-YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGD-----QQAWFGFA---GTPG-----YLSPEVLRKDP .. . .| . || . .. | ....|||| | |.... || .||||. .. | . . |. . ..||.... HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YGKPVDMWACGVILY-ILLVGYPPFWD-----EDQHRLYQQIKAGAYDFPSPE-----WDTVTPEAKDLINKMLTINPAKRITASEALKHPWI . | |. || .. |. | .| .. . ......|.| . . |. . ..| ... . .|..| | || | . FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | CaMK2d.AA | Pkinase_Tyr | 14-98 | 26 | 4.8e-07 | 24.48 | Pfam | 1-94 (270) | Show / Hide |
Range on Protein: 14-98 Range on HMM: 1-94/270 Sequence Identity: 26% (25 aa) YQLFEELGKGAFSVVRRCMKI----PTGQEYAAKIINTKKLSARD--HQKLEREARICRLL-KHPNIVRLHDSIS-EEGF--HYLVFDLVTGGEL .. ..||.||| .|... |... | |.. . . .. .... |||.| . | .|||||||. .. ... .|.|. .. .| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL |
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| Kinase | CaMK2d.AA | Pkinase_Tyr | 128-167 | 35 | 0.175891 | 5.64 | Pfam | 128-164 (270) | Show / Hide |
Range on Protein: 128-167 Range on HMM: 128-164/270 Sequence Identity: 35% (14 aa) HLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGD . ....|||| | |... . || .||||| .. | ESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYND |
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| CaMKII_AD | CaMK2d.AA | CaMKII_AD | 380-507 | 67 | 9.6e-94 | 322.54 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 380-507 Range on HMM: 1-128/128 Sequence Identity: 67% (87 aa) RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPK .||||.||||..||||..||...|||.|.|..|.||.||.|||||||.|||||||....|..|..||..||||||..||||||.||.||||||| .||.. EKQEIWKVTERWIEAIYCGDWHTYTKLCHPDMTCFEWEACGNLVEGMEFHRFYFEMHWTKRCKAVHTTMLNPHVHMYGDDAACCAYVRLTQYMDKNGMAH TMQSEETRVWHRRDGKWQNVHFHRSGSP |.|||||||||.||||||.||.|||..| TRQSEETRVWHKRDGKWQCVHHHRSAMP |
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