Gene CaMK2b (Mouse)

CaMK2b

Species: Mouse
Alias: Camk2b, CaMK2b
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: CAMK2

Sequence

Name Sequence Type Origin Length Description Download
CaMK2b.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 259 Kinase domain by global Sugen HMM Fasta, JSON
CaMK2b.NA RNA Sugen 4191 None Fasta, JSON
CaMK2b.AA Protein Sugen 666 None Fasta, JSON

Protein domain

Protein domains of CaMK2b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CaMK2b.AA CAMK2 14-272 92 2.1e-222 745.11 In-house 1-259 (259) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-259/259
Sequence Identity: 92% (240 aa)

YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADA
|||.|..|||||||||||||.|||.||||||||||||||||||||||||||||.|||.|||||||||.||||||||||||||||||||||||||||||||
YQLFEELGKGAFSVVRRCVKKCTGQEYAAKIINTKKLSARDHQKLEREARICRKLKHPNIVRLHDSIQEEGFHYLVFDLVTGGELFEDIVAREYYSEADA

SHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPP
|||||||||.| ||||.|.||||||||||||||||||||||||||||||||||||||||||||||||||||||||..|||||||||||||||||||||||
SHCIQQILESVNHCHQNGIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPP

FWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWV
|||||||.|||||||||||.||||||||||||||||||||||||.|||||.|||||||.
FWDEDQHRLYQQIKAGAYDYPSPEWDTVTPEAKNLINQMLTINPKKRITADEALKHPWI
Kinase CaMK2b.AA CAMK1 14-272 42 2.6e-145 425.39 In-house 1-276 (276) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-276/276
Sequence Identity: 42% (118 aa)

YQLYEDIGKGAFSVVRRCVKLCT---GHEYAAKIIN-TKKLSARDH---QKLEREARICRL---LKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIV
|.. . ||.||||.|..|..  |   |..|| |.|.  | ..  |    ..||.|  | .    ..| ||. ...   .. . ||| .||||||||. ||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

AREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK---EAYGKPVDIW
 ...|.| ||.|...|||.|| ..|..|.|||||||||||...|  .. .|  .|||||.  . .|    .   |||||  ||||     ..|.|..|.|
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

ACGVILYILLVGYPPFWDED-QHKLYQQIKAGAYDFPSPEWDTVTPE-AKNLINQMLTINPAKRITAHEALKHPWV
 .|||.||||.|||||.||. ...|...|| . |.||||.|| .  . ||..|..||. .| ||.|. ..|.|||.
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CaMK2b.AA CAMK 19-272 24 7.50000000001e-131 424.16 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-272
Range on HMM: 1-425/425
Sequence Identity: 24% (106 aa)

DIGKGAFSVVRRCVKLCTG------------HEYAAKIINTKKLS--------------------------ARDHQKLEREARICRL-------LKHSNI
 .|.|.|..|..|.   |.            ...|.|||..|||.                          ..| ....|| .|...       |.| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLHDSISEEGF-------------------HYLVF---DLVTGGEL----FEDIVAREY---------------YSEADASHCIQQILEAVLHCHQMGV
..|.. .  . .                    |.|.   ....||||    |. ||....               ..|..|.....||..|| .||....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENLLLASKCKG--------------AAVKLADFGLAIEVQGDQ-----------------------QAWFGFAGTPGYLS-PEVLRK------
|||||||||.|| .. ..              . .|..|||.|.......                       |    | |||.| . ||||..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EAYGKPVDIWACGVILYILLVGYPPFWDE-------------DQHKLYQQIKAGAYDFPSPE------------WDTVTPE--------AKN
        . ||...|.|.|||||||.|.|||||...             ....|...|..| ||||.|.            || .. |        .|.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LINQMLTINPAKRITAHEALKHPWV
||..||. .| ||.|....|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CaMK2b.AA RAD53 14-272 33 1.5e-108 324.53 In-house 1-305 (305) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-305/305
Sequence Identity: 33% (104 aa)

YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLS---ARD---HQKLEREARICRLLKHSNIVRLHDSISE-EGFHYLVFDLVTGGELFEDIVARE
| . . .|.|.|..|.....  |.  .| |||..||..    ..      ...|..| . |.| .|.|..|.. . .   |.|  |.||||||..||...
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

Y----YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGA---------------AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLR
.    ..|...     |...||.  | .| .|||||||| |.... ..                ..|..||||.  ..|...    . ||| |. |||..
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLS-KFVGEGSFMKTMCGTPQYVAPEVIT

KE---------------AYGKPVDIWACGVILYILLVGYPPFWDE-DQ----HKLYQQIKA-GAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEA
..               .|.| ||.|  |.||||.| ||||| |. .|     .|..|||  | | ||.|.|| .. |||.||..||...| ||.|. ||
SKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA

LKHPWV
| ||| 
LNHPWM
Kinase CaMK2b.AA S_TKc 14-272 36 8.10000000001e-106 358.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-231/231
Sequence Identity: 36% (99 aa)

YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTG--GELFEDIVAREY----
|.. . ||||||..|..|..  ||...| |||.         ....|| .|..  .| |||.|.|.. . .. |.|.... |  |.||. |. | .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGK-PVDIWACGVIL
  ..| .| . ..||..|. .||..|..||||||||.|| .      .|..||||| ..         | ||| |..||||    ||| ..|.|.||.||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALK-------HPWV
|..|.|||||.  ........|.              .||||..|...|. .|.||.|| |||.       |||.
YEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CaMK2b.AA DCAMKL 14-272 40 2.4e-105 328.78 In-house 1-279 (279) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-279/279
Sequence Identity: 40% (113 aa)

YQLYEDIGKGAFSVVRRCVKLCTG-HEYAAKI-----------------INTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTG
||.   ||.| |.||  |..  || |.|| ||                 |. .|.    |   . | .| ...|| .|..|... . |   |||. .|.|
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHM-IDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQG

GELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKP
| ||. |.    ..| ||.  . .. .|  . | |..||||.||||||.     .   .||.||||| .|.||    .   ||| |  ||.|..  ||  
GDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK

VDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWV
||||| ||||||||.|.|||  .  || .|  || .|...||.|.|| ..  ||.||..||  .| || ||.. ..||||
VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CaMK2b.AA CDPK 14-272 38 1e-104 322.07 In-house 1-271 (271) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-271/271
Sequence Identity: 38% (105 aa)

YQLYEDIGKGAFSVVRRCVKL-CTGHEY-AAKIINTKKLSARDH-QKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFD--LVTGGELFEDIVAREYY
|.. . .|||.|..||....   |. |  | |||. ....  .  |.. .|  | . | | ||...      | ..|.|.   ..||||||. |... ..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGA----AVKLADFGLAIEVQGD----QQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWAC
.| .|.  ..||| || .||. ..|||||||||.|. || ...     .|. |.|.. . ...     .    ..||| |..||||.|  | . .||| |
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWV
||||||||.|||||. . . . ....| | |.|  |||| .. |||.||..||. .| ||..| .||.|||.
GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase CaMK2b.AA Pkinase 14-272 34 5.5e-96 329.98 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-293/293
Sequence Identity: 34% (101 aa)

YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER--EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG----ELFEDIV--AR
|.. . ||.|.|..|..|..  ||...| |||. .. .   .| . |  |..| . |.| |||||.|.  ...  |.|.... ||    .||. |   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EYY--SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKG-AAVKLADFGLAIEV-QGDQQAWFGFAGTPGYLSPEVLR-KEAYGKPVDIWAC
  .  || .. ... |||... .||.||..||||||||.|. ...   | ||..|||||  .    ..   .|.|||.|..|||.|  . ||..||.|.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYILLVGYPPFWDE------DQHKLYQQIKAGAYDFPSPEWDTVT-----------------PEAKNLINQMLTINPAKRITAHEALKHPWV
|.|||..| |.|||...      || .....|. . ..|..|.|...                  .|.| .|. .|. .|.||.||...|.|||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CaMK2b.AA CAMKL 14-272 33 1.1e-94 302.54 In-house 1-297 (297) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-297/297
Sequence Identity: 33% (102 aa)

YQLYEDIGKGAFSVVRRCVK-LCTGHEYAAKIINTKKLS--------------ARDHQKLEREARICRLLK---HSNIVRLHDSISEEGF------HYLV
|.. . .|||.|..|. ..  . ||...| |||. ||..               .|  ...||..| ..|.   | ||..|.. |  . .       |||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

FDLVTGGE--LFEDIVAREY----YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIE---V-QGDQQAWFGFAGTPG
  .. |||  ||. ||....     .| .| .  .||..|| .||..|.||||.||||.|| .. .   .|..|||....   .  |. |    | |.| 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YLSPEVLRK--E-AYGKPVDIWACGVILYILLVGYPPFWDE--------DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALK
| .||.. .  .  .|..||||.|||||| ...|| || |.        .. .|| .|. | | .|   |  |  ....|| .||. || ||.|.|. ..
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

HPWV
|||.
HPWM
Kinase CaMK2b.AA CAMK-Unique 14-272 24 7.7e-89 293.4 In-house 1-363 (363) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-363/363
Sequence Identity: 24% (88 aa)

YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLS-ARDHQ-----------------KLEREARICRLLKHSNIVRLHDS----ISEEG-------
| . . ||.|.|..|..|    || ..| |... .. .  . .|                 ||.||..| ....| ||..| |        .        
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------FHYLVFDLVTGGELFEDIVA--------------------REYYSE--ADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASK-------
          |.| ....||.||. |..                    . ..||  .|..  .|..|.|| . |. ..||||||.||... .        
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

------CKGAAVKLADFGLAIEVQGDQQA--WFGFAGTPGYLSP--------------EVLRKEAYGKPV----DIWACGVILYILLVGYPPFWDEDQH-
      ..   .||.||||. .... .       . ||| |..|              ||.    |. ..    |||..|||.|..|.|.|||  |.   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------KLYQQIKAGAY-DFPSPEWDT---VTPEAKNLINQMLTINPAKRITAHEALKHPWV
       .... |..| | .|... |.    ...|||... . .|. |..|..| |.|.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CaMK2b.AA MARK 14-272 36 3.5e-88 288.36 In-house 1-262 (262) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-262/262
Sequence Identity: 36% (98 aa)

YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSA-RDHQKLEREARICRLLKHSNIVRLHDSIS--EEGF-HYLVFDLVTGGELFEDIVAR--EY
| .   ||.|....|. .. ..|| ..| ||.. .||.     ....||..| ..|.| ||..|.. |   .|.   ||. ... ||||.. |.|.   .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYG-KPVDIWACGVILYI
 .| .| .  .||..||  ||....||||.||||.|. .. .   .|..|||..|... .|     | ||| | .||.. |. |  ..||||..||.||.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGN-HNIKIIDFGFSICIPPGQK-LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

LLVGYPPFW--DEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWV
...|| ||   . |. .||..| .| ||.|.     | .|..|||...||.|| .|.|..| .||||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase CaMK2b.AA RSK 16-272 31 1.3e-87 297.43 In-house 1-278 (278) Show / Hide 
Range on Protein: 16-272
Range on HMM: 1-278/278
Sequence Identity: 31% (89 aa)

LYED--IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDH-QKLER-EARICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY---
| ..  .|.|.....|.|.   ||..|| |... .|. .|.  ..  . | .|  . . | .||.||..  .||  ||. ... |||||. .  ...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKG-AAVKLADFGLAIE-VQGDQQAWFGFAGTPGYLSPEVLR----KEAYGKPVDIWACG
 || .|.  . .|  || | || |..|||||||| |....  . . .|| |||.. . .  . |    | .|  |. ||.|.    .....| .|.|  |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VILYILLVGYPPFWD---EDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRIT-----AHEALKHPWV
|..| .|.|.|||     ...... ..|. | .....|.|.....|||.||..||. .|.||..     | | ..||| 
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CaMK2b.AA TyrKc 14-270 20 2.3e-14 9.71 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLL--KHSNIVRLHDSISEE-------GFHYLVFDLVTGGELFEDIVA
 .| . .| ||| .|....      . | | ..  .     .. . ||||| . |  .| |||||.  ....       . ...|. .. .| | . . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

REY-YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGD-----QQAWFGFA---GTPG-----YLSPEVLRKEA
..   . .|  .   || .   . |.....||||   | |....     || .||||. ..  |      .     .   |. .      ..||....  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YGKPVDIWACGVILY-ILLVGYPPFWD-----EDQHKLYQQIKAGAYDFPSPE-----WDTVTPEAKNLINQMLTINPAKRITAHEALKHP
.    |.|. || .. |.  | .| ..      .   .....|.| .  . |.       . ..|  ... |    .|..| |  |  .  
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CaMK2b.AA Pkinase_Tyr 14-98 23 8e-05 16.95 Pfam 1-94 (270) Show / Hide 
Range on Protein: 14-98
Range on HMM: 1-94/270
Sequence Identity: 23% (22 aa)

YQLYEDIGKGAFSVVRRCVKL--CTGHEY--AAKIINTKKLSARD--HQKLEREARICRLL-KHSNIVRLHDSIS-EEGF--HYLVFDLVTGGEL
 .. . .|.||| .|....      ....  | |..   . . ..  .... |||.| . | .| |||||.  .. ...   .|.|. .. .| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase CaMK2b.AA Pkinase_Tyr 128-167 35 0.056513 7.31 Pfam 128-164 (270) Show / Hide 
Range on Protein: 128-167
Range on HMM: 128-164/270
Sequence Identity: 35% (14 aa)

HQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGD
.... .||||   | |...   .  || .|||||  .. |
ESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYND
CaMKII_AD CaMK2b.AA CaMKII_AD 534-661 63 4.3e-86 297.13 Pfam 1-128 (128) Show / Hide 
Range on Protein: 534-661
Range on HMM: 1-128/128
Sequence Identity: 63% (81 aa)

RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPR
.||||.| ||..|||...||...|.|.|.|..| ||.||.|||||||.|||||||....|..|..|||.|||||| .|.||||.||.|||||.| .| ..
EKQEIWKVTERWIEAIYCGDWHTYTKLCHPDMTCFEWEACGNLVEGMEFHRFYFEMHWTKRCKAVHTTMLNPHVHMYGDDAACCAYVRLTQYMDKNGMAH

TSQSEETRVWHRRDGKWQNVHFHCSGAP
| |||||||||.||||||.||.| |..|
TRQSEETRVWHKRDGKWQCVHHHRSAMP