Gene BRD3 (Mouse)

BRD3

Species: Mouse
Alias: Brd3, BRD3
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Atypical
Family: BRD

Sequence

Name Sequence Type Origin Length Description Download
BRD3.NA RNA Sugen 3058 None Fasta, JSON
BRD3.AA Protein Sugen 743 None Fasta, JSON

Protein domain

Protein domains of BRD3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
BROMO BRD3.AA BROMO 31-141 41 1.7e-48 168.38 SMART 1-118 (118) Show / Hide 
Range on Protein: 31-141
Range on HMM: 1-118/118
Sequence Identity: 41% (49 aa)

PGRKTNQLQYMQNVVVKTLWKH--------QFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIV
. .  ...| . ..|.. . .|        ..||||.||||...||.|||..|||||||..||||.|||..|.|. | ..||. ||.||..||.|  .. 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

LMAQALEKIFLQKVAQMPQ
 ||. |.| |..| ...|.
KMAKKLQKFFEEKWREFPP
Bromodomain BRD3.AA Bromodomain 41-127 35 3.5e-27 91.03 Pfam 1-89 (89) Show / Hide 
Range on Protein: 41-127
Range on HMM: 1-89/89
Sequence Identity: 35% (32 aa)

MQNVV-VKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYW-SASECMQDFNTMFTNCYIYNKPTDDIVLMAQA
..... .|....| ...|| .||| .. ..|||..|||.|||. ||...|.||.|  .  | . |.. |..||..||.| ..|  .|. 
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK
BROMO BRD3.AA BROMO 307-416 41 2.9e-47 164.24 SMART 1-118 (118) Show / Hide 
Range on Protein: 307-416
Range on HMM: 1-118/118
Sequence Identity: 41% (49 aa)

LSEHLRHCDSILREMLSKKHAA---------YAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVV
 .. .. | ..|.|....||           |||||..|||.  |...||.||||.||||.|.|.|.....| ... |..|..|||.||..||.||.|| 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

AMARKLQDVFEMRFAKMPD
 ||.|||..|| .....|.
KMAKKLQKFFEEKWREFPP
Bromodomain BRD3.AA Bromodomain 314-402 40 3.2e-30 100.97 Pfam 1-89 (89) Show / Hide 
Range on Protein: 314-402
Range on HMM: 1-89/89
Sequence Identity: 40% (37 aa)

CDSILR--EMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDSREYP-DAQGFAADIRLMFSNCYKYNPPDHEVVAMARK
|| |..  ......    ..|| .||| .  |. ||.|||||||||||...|.....|    ..| .|..||..||..||.||... ..|||
CDQIMDMKYIMEHP---ICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK