Gene BRD2 (Mouse)

BRD2

Species: Mouse
Alias: Brd2, BRD2
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Atypical
Family: BRD

Sequence

Name Sequence Type Origin Length Description Download
BRD2.AA Protein Sugen 798 None Fasta, JSON
BRD2.NA RNA Sugen 3621 None Fasta, JSON

Protein domain

Protein domains of BRD2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
BROMO BRD2.AA BROMO 71-181 40 8.2e-46 159.44 SMART 1-118 (118) Show / Hide 
Range on Protein: 71-181
Range on HMM: 1-118/118
Sequence Identity: 40% (48 aa)

PGRVTNQLQYLHKVVMKALWKH--------QFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIV
. .  ...| | |.||... .|        ..||||.||||...|..|||..|||.|||..|||..|||..|. . | ..||. ||.||..||.|  .. 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

LMAQTLEKIFLQKVASMPQ
 ||..|.| |..| . .|.
KMAKKLQKFFEEKWREFPP
Bromodomain BRD2.AA Bromodomain 82-167 35 1.1e-26 89.4 Pfam 1-89 (89) Show / Hide 
Range on Protein: 82-167
Range on HMM: 1-89/89
Sequence Identity: 35% (32 aa)

HKVVMK--ALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYW-AASECMQDFNTMFTNCYIYNKPTDDIVLMAQT
 . .|.   ...| ...||..||| .. ..|||..|||.|||. ||...|.||.|     | . |.. |..||..||.| ..|  .|..
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK
BROMO BRD2.AA BROMO 345-454 44 4.4e-50 173.63 SMART 1-118 (118) Show / Hide 
Range on Protein: 345-454
Range on HMM: 1-118/118
Sequence Identity: 44% (53 aa)

LSEQLKHCNGILKELLSKKHAA---------YAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVV
 .. .| |. .|||....||           |||||..|||.. |...||.||||.||||.|.|.|.||. |....||..|..|||.||..||.||..| 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

AMARKLQDVFEFRYAKMPD
 ||.|||..|| .....|.
KMAKKLQKFFEEKWREFPP
Bromodomain BRD2.AA Bromodomain 352-440 41 1.9e-31 104.95 Pfam 1-89 (89) Show / Hide 
Range on Protein: 352-440
Range on HMM: 1-89/89
Sequence Identity: 41% (38 aa)

CNGILK--ELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYR-DAQEFAADVRLMFSNCYKYNPPDHDVVAMARK
|  |..  ......    ..|| .||| .  .. ||.|||||||||||...|..|. ||   .|| .|..||..||..||.||... ..|||
CDQIMDMKYIMEHP---ICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK