Gene BMPR1B (Mouse)
BMPR1B
Sequence
Protein domains of BMPR1B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Activin_recp | BMPR1B.AA | Activin_recp | 30-110 | 22 | 1.2e-29 | 100.12 | Pfam | 1-121 (121) | Show / Hide |
Range on Protein: 30-110 Range on HMM: 1-121/121 Sequence Identity: 22% (27 aa) LRCK-CHHH-------CPEDSVN-----NICST----------DGYCFTMIEEDDSG--MPVVTS----GCLGLEGSD-----FQCRD-----TPIPHQR |.| |... |.|. .| ..|.| ||.|....|..| . ...... ||. |.... |.|.. | .... LKCYFCNGYWEYDYQICHENENNFEIPVHTCETHPDKMCFYCYDGQCYVSWEYNDDEEDTEQHQRMHMYGCWSLNENCPQCHPFMCKSYKHTHSPPHRHG RSIEC-CTERNECNKDLHPTL ...|| |.|.. ||..|.|.. HNHECWCCETDYCNRNLTPPP |
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Kinase | BMPR1B.AA | Type1 | 204-491 | 72 | 2e-277 | 761.44 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 204-491 Range on HMM: 1-290/290 Sequence Identity: 72% (211 aa) IQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLK |||...||||||||||.||||||.||||.||...|.||||||||||||.|||||||||||||.|..||||||.|||||||.|||||||...|||...||. IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDNGSWTQLWLITDYHEHGSLYDYLNRHTLDTQQMLR LAYSSVSGLCHLHTEIFSTQ--GKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMY |||| ..||.|||.|||.|| |||||||||.|||||.|||||.||||||||||.. .||...||..|.||||||||.||||||..| |.|.||.|||.| LAYSCACGLAHLHMEIFGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDTDQIDIGQNPRVGTKRYMAPEVLDETMNMNCFESYKMADIY SFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSSDECLRQMGKLMTECWAQNPASRLTALRVKKTL ||||..|||||||..|||||.|||||.|.||.|||.||||..||..||||..||||.|..|.|.|.|||.|||.|||..|.||||.|||| SFGLVMWEIARRCEVGGIVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQSHPCMRHMAKLMKECWYQNPHARHTALRIKKTL |
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Kinase | BMPR1B.AA | STKR | 204-491 | 58 | 4.3e-220 | 717.64 | In-house | 1-312 (312) | Show / Hide |
Range on Protein: 204-491 Range on HMM: 1-312/312 Sequence Identity: 58% (184 aa) IQMVKQIGKGRYGEVWMGKWRG----EKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGT-GSWTQLYLITDYHENGSLYDYLKSTTLDA ||....||||||||||.||||| |.||||.|....|.|||||||||||..|||||||.|||||.|.| |||||..|||.|||||||.||||..|.| IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTIDW KSMLKLAYSSVSGLCHLHTEIF--STQ--GKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIP-------PNTRVGTKRYMPPEVLDESL ..|...|.| .||.|||.||. .|| .||||||||.||||||||..|||||||.|||... .|||..||. .||.|||||||.|||||... HEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGAM NRNHFQS-YIMADMYSFGLILWEIARRCVSGG------IVEEYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWS-SDECLRQMGKLMTECWAQNPA | ..|.| . ..|||..||..||||||| .|| ||.|||.|..| ||..||.|||...||.|..||..||||. .....|.| |.|.||| ..|. NFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDPE SRLTALRVKKTL |||||.||||. ARLTALCVKKTM |
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Kinase | BMPR1B.AA | Type2 | 204-491 | 39 | 2.2e-111 | 369.09 | In-house | 1-315 (315) | Show / Hide |
Range on Protein: 204-491 Range on HMM: 1-315/315 Sequence Identity: 39% (125 aa) IQMVKQIGKGRYGEVWMGKWRGE-----KVAVKVFFTTEEASWFRETEIYQT-VLMRHENILGFIAADI---KGTGSWTQLYLITDYHENGSLYDYLKST ||. .|||||.|.|| ..| .. ||||.| . .|| | .||.. ..|.||||| ||.|. ... | .. |.|..|..|||.||||. IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQH TLDAKSMLKLAYSSVSGLCHLHTEIF-STQ---GKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNE----VDIPPNTR----VGTKRYMPPEV |.| ......| | || |||.|| ..| ||.|||||.||||.||| ..||||||.|||..| .... . | | |||.||| ||| TIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPEV LDESLNRNH-FQSYIMADMYSFGLILWEIARRCVSGG---IVEEYQLPYHDLVPSD-PSYEDMREIVCMKKLRPSFPNRWSSDECLR-QMGKLMTECWAQ |. .| . . .|||..||.|||.. || . | |||.|. | . || |||.| | .|. || .|. |. . . . ....|| . LEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYPDDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWDH NPASRLTALRVKKTL . ||||. |. . DAEARLTAQCVQERM |
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Kinase | BMPR1B.AA | TKL | 210-491 | 30 | 5e-111 | 375.17 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 210-491 Range on HMM: 1-364/364 Sequence Identity: 30% (114 aa) IGKGRYGEVWMGKWRG----------EKVAVKVFFTTE-------------------------EASWFRETEIYQTVLMR---HENILGFIAADIKGT-- ||.|..|||. ||||| . ||||.| ... ||||||..|......|. |.||. |..... .. IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG -------GSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIF--STQGKPAIAHRDLKSKNILVKKNGT--------------C |.|.||.....|...|||..|| ....|.. .|...||.... .| ||.|.|||||||||||..|.| | CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT--KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC CIADLGLAVKFISDTNEVDIP---------------PNTRVGTKRYMPPEVLDESLNRNH----------FQSYIMADMYSFGLILWEIARRCVSGGIVE .|.|.||. . ..| |. .|..||.|.|.||||....| .. |. .|.||||..||||. ||. KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----P EYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSS-------DECLRQMGKLMTECWAQNPASRLTALRVKKTL .|..|| . ...|| .|.| ..|| |.||| |..|.. . |...| |||..||...| .|.......|.| YYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | BMPR1B.AA | Pkinase | 204-491 | 21 | 9.9e-59 | 206.22 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 204-491 Range on HMM: 1-293/293 Sequence Identity: 21% (71 aa) IQMVKQIGKGRYGEVWMGKWRGEK--VAVKVFFTTEEASWFRET-----EIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENG----SLYDYLK .. ...||.| .|.|. ....|. ||||.. .| ||...| ||. ..|.||. .. . . .|....|.|.| .|.||.. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIS ---STTL--DAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTC----CIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVL .... . . . .| ..|| ..| . | |||||. |||...||.. .|.| ||| .| . . ..|..|| .||.|||. TWRHGCFYFSEWECKFYMYQILRGLEYCHSM--------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVI DESLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSSDECL-----------------RQM . .||.|.|.||.| . . .|. . . ... |.....|... .| ... ... . . R-----GGQYYGPKVDMWSCGCILYEMLCGR----------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC GKLMTECWAQNPASRLTALRVKKT--L .... |....|..|.|| ... . KDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | BMPR1B.AA | TKL-Unique | 206-481 | 29 | 1.4e-40 | 140.81 | In-house | 1-280 (290) | Show / Hide |
Range on Protein: 206-481 Range on HMM: 1-280/290 Sequence Identity: 29% (90 aa) MVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETE-IYQTV----LMR-HENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLK------- .. || | ||.| |||||..||.|.|. .| | ..... . | . |.||. .... .. . . .......| . |||||.| FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN ----STTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKN-----GTCCIADLGLAVKFISDTNEVDIPPN------TRVGTKRY ...|. . ..|.| ..|...||... .| |.||||||.|.|| | |.| ||. || | |. . . ||.|. |. NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCE-----PP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLS-KFNSKINKMTNNEHKGTRNQTRCGSFRW MPPEVLDESLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCM--KKLRPSFPNRWSSDECLRQMGKLMTECWA |.|||| . .... . .| |||| .||||| |.. | ||... . | .|.| ...|| || .| . .|...||. MAPEVLRMNF--CQYS--EKSDVYSFGIVLWEIATRKI----TKTYKKPYQGM-----DQEQWCEMVHYMEENYRPPIPN-----HCPKEYRDLIQQCWH QNPASR ..| | HDPSQR |
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Kinase | BMPR1B.AA | MLK | 204-410 | 26 | 7.4e-34 | 114.87 | In-house | 1-229 (291) | Show / Hide |
Range on Protein: 204-410 Range on HMM: 1-229/291 Sequence Identity: 26% (65 aa) IQMVKQIGKGRYGEVWMGKWRGEK-----VAVKVFF-------TTEEASWFRETEIYQTVLMRHEN----ILGFIAADIKGTGSWTQLYLITDYHENGSL || . ||.| .|.|| |.||.. |||| .. |.. .| |.|... ..|.| | | .. .. . ...... | |.||| IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP---CHFCIVMEYCEGGSL YDYLKSTT---------------LDAKSMLKLAYSSVSGLCHLHTEIFSTQGKP-AIAHRDLKSKNILVK------KNGTCCIADLGLAVKFISD-TNEV |..|.. . | .... |. .|. || . .| .| ||||||.|||. ..||. |.| |.. .. . || YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSM------APKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMM DIPPNTRVGTKRYMPPEVL---DESLNRNHFQSYIMADMYSFGLILWEI . . || ..| |||. .. . . .|..|.|..|||. S-----NAGTYAWMAPEVIQQFRCEKYS------EKCDVWSWGVVLWEM |
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Kinase | BMPR1B.AA | S_TKc | 204-493 | 19 | 9.1e-32 | 112.77 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 204-493 Range on HMM: 1-231/231 Sequence Identity: 19% (62 aa) IQMVKQIGKGRYGEVWMGKWRG--EKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHEN--GSLYDYLKSTT---- .....|||| .|.|. ..... ..||.|. . || .| . .|.|| .. . . ||....| .. |.|.||.|. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHF .. ...| ...| ..| | ||||| |||. . . |.| ||| .. .| .|| ||.|||| RFPFPE-HARFYMYQICCALEYCHSH-G-------IIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL--------- QSYIM--ADMYSFGLILWEIARRCV--SGGIVEEYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSSDECLRQMGKLMTECWAQNPASRLTALRVK .| .|..|.| ||.| . .. . ..|. .. .. ... .. |. .|. |.|| . -GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-------------------------------SPEAKDFIRKCLQKDPEKRPTA-EAL K-------TLAK . QDEWDIKCHPWF |
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Kinase | BMPR1B.AA | TK | 204-410 | 15 | 3.5e-27 | 87.53 | In-house | 1-387 (486) | Show / Hide |
Range on Protein: 204-410 Range on HMM: 1-387/486 Sequence Identity: 15% (62 aa) IQMVKQIGKGRYG---EVWMGKWRG---------------------------EKVAVKVFF---TTEEASWFR-----------------ETEIYQTVLM |...|..|.| .| ||..|.||| ..||||. ..... | | .. . | ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG RHENILGFIAADIKGTGSW--------TQLYLITDYHENGS----LYDYLKSTT---------------------------------------------- .|.||. .... .| .. ..... | ..|. | |||.. HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY -------------------------------LDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGT-----------CCIADLGL |. . .| .. .|. .|| .. . . . |||| |.|| .|.. | ||| || DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE--FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL AV-----KFISDTNEVDIPPNTRVGT-------------------------KRYMPPEVLDESLNRNH---FQSYIMADMYSFGLILWEI . . .. | . || |.|.||.|.. . . . |..||| .||| SRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI |
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Kinase | BMPR1B.AA | STE | 204-411 | 19 | 1.8e-21 | 72.67 | In-house | 1-262 (359) | Show / Hide |
Range on Protein: 204-411 Range on HMM: 1-262/359 Sequence Identity: 19% (55 aa) IQMVKQIGKGRYGEVWMGKWR-----------------GEKVAVKVF--------------------FTTEEASWFRETEIYQTVL-MRHENILGFIAAD . ...|||| .|.| .. . || .|.|. ...|. . .| .| . | |.|| .. . WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY IKG---TGSWTQLYLITDYHENGSLYDYLKST-----TLD----------AKSMLKLAYSSVSG-LCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTC .|. ... ..|... | ..||| | .|.. .|. . . ... . | | .|| | |||.|. |||. . FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--------IIHRDIKPANILL-----V CIADLGLAVKFISDTN------------EVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSY-IMADMYSFGLILWEIA ..| |.. ..... . || ||| .| |||.. . . | . .|..|.|. ..| | KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMA |
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Kinase | BMPR1B.AA | TyrKc | 204-491 | 25 | 3e-17 | 56.12 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 204-491 Range on HMM: 1-280/280 Sequence Identity: 25% (78 aa) IQMVKQIGKGRYGEVWMGKWRGEKVAVKVFF-TTEEASWFRETEIYQTVLM--RHENILGFIAADIKGTGSW---TQLYLITDYHENGSLYDYLKSTT-- |.. |..| | .|||. |.|. ..||||. . .. || .| .|.||. .... ... . . .|.... | ..|.| |||... ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCK--LGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK LDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDT-----NEVDIPPNTRVGTK-----RYMPPEVLDE | | .|. .. .| .|| . |||| |.||..|.|. |.| ||. ..| | .. . . .. |.| | |.||.. LCMKDLLSFCWQIACGMEYLHSK--------NCIHRDLAARNCLVGENHTVKISDFGLS-RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-- SLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSSDE-----CLRQMGKLMTECWAQNPAS |. . | .||| .||| .. | || . . . | ....| | . .| || . | | ..|..||. .|.. ----NYGKFTTKSDVWSFGVCMWEIFTYG---------QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---PMSFVCCPDEMYQIMKQCWHEDPED RLTALRVKKTL | | ... . RPTFSEIHECF |
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TGF_beta_GS | BMPR1B.AA | TGF_beta_GS | 174-202 | 62 | 1.2e-16 | 57.75 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 174-202 Range on HMM: 1-29/29 Sequence Identity: 62% (18 aa) ESLRDLIEQSQSSGSGSGLPLLVQRTIAK ....|..|....||||||||||||||||. KTMQDMMEDFCTSGSGSGLPLLVQRTIAR |
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Kinase | BMPR1B.AA | Pkinase_Tyr | 204-306 | 25 | 1.7e-15 | 53.12 | Pfam | 1-118 (270) | Show / Hide |
Range on Protein: 204-306 Range on HMM: 1-118/270 Sequence Identity: 25% (31 aa) IQMVKQIGKGRYGEVWMGKWR------GEKVAVKVF--FTTEE----ASWFRETEIYQTVLM-RHENILGFIAADIKGTG-SWTQLYLITDYHENGSLYD |.. |..|.| .|||..|.|. . .||||. ...| .. .|| .| . . .|.||. .... .. . . |.|... | ..|.|.| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQ--LGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLD YLKST-----TLDAKSMLKLAY ||.. |. | .|. .. YLRKHREDKQPLTMKDLLQMCW |
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GS | BMPR1B.AA | GS | 174-204 | 61 | 2.9e-15 | 57.94 | SMART | 1-31 (31) | Show / Hide |
Range on Protein: 174-204 Range on HMM: 1-31/31 Sequence Identity: 61% (19 aa) ESLRDLIEQSQSSGSGSGLPLLVQRTIAKQI ....|..|.. .||||||||||||||.|.|| KTMHDMMEDTCTSGSGSGLPLLVQRTVARQI |
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Kinase | BMPR1B.AA | CAMK | 328-383 | 27 | 3.6e-13 | 38.08 | In-house | 200-292 (425) | Show / Hide |
Range on Protein: 328-383 Range on HMM: 200-292/425 Sequence Identity: 27% (26 aa) IAHRDLKSKNILVKKN-----------------GTCCIADLGLAVKFISDTNEV-------------------DIPPNTRVGTKRYMP-PEVL |.||||| |||. .| .. |.| |.| ||... |. . . .|..|| ||. |||| IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVL |
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Kinase | BMPR1B.AA | CAMK | 209-293 | 13 | 9.4e-12 | 33.42 | In-house | 1-157 (425) | Show / Hide |
Range on Protein: 209-293 Range on HMM: 1-157/425 Sequence Identity: 13% (21 aa) QIGKGRYGEVWMGKWR-G-------------EKVAVKVFFTT-------------------------------EEASWFRETEIYQTVL-----MRHENI ..|.|..|.| .. . .|||.|. .. ... .|| || ... ..|.|| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI LGFIAADIKGTG--------SWTQ--------LYLIT---DYHENG----SLYDYLKS . .. . .. . .. .|... .| ..| |.||... IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVE |
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Kinase | BMPR1B.AA | Dicty4 | 204-236 | 48 | 7.2e-11 | 32.66 | In-house | 1-33 (277) | Show / Hide |
Range on Protein: 204-236 Range on HMM: 1-33/277 Sequence Identity: 48% (16 aa) IQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTT |. . |||| .||| |.||| .||||... . INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNH |
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Kinase | BMPR1B.AA | Dicty4 | 285-383 | 30 | 3e-08 | 23.78 | In-house | 87-189 (277) | Show / Hide |
Range on Protein: 285-383 Range on HMM: 87-189/277 Sequence Identity: 30% (35 aa) GSLYDYLKS--------TTLDAKSMLK---LAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAV--KFISDTNE-VDIPPNT |.|| | . ..|| ... .| . . |. .||. . | | |||||| |.|| || . ..|.||. | ..| . . | GNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCN------PVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQM----T RVGTKRYMPPEVL .|| .| |||. ACGTPCWMAPEVM |
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Kinase | BMPR1B.AA | Pkinase_Tyr | 330-354 | 52 | 3.1e-05 | 18.36 | Pfam | 134-158 (270) | Show / Hide |
Range on Protein: 330-354 Range on HMM: 134-158/270 Sequence Identity: 52% (13 aa) HRDLKSKNILVKKNGTCCIADLGLA |||| .|.||..|... |.| ||| HRDLAARNCLVTENNVVKICDFGLA |
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Kinase | BMPR1B.AA | TK | 469-491 | 34 | 3.5e-05 | 12.49 | In-house | 464-486 (486) | Show / Hide |
Range on Protein: 469-491 Range on HMM: 464-486/486 Sequence Identity: 34% (8 aa) LMTECWAQNPASRLTALRVKKTL ||..||. .|. | | ... | LMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | BMPR1B.AA | Dicty4 | 398-411 | 71 | 0.000135 | 11.44 | In-house | 198-211 (277) | Show / Hide |
Range on Protein: 398-411 Range on HMM: 198-211/277 Sequence Identity: 71% (10 aa) ADMYSFGLILWEIA || ||||..||||. ADVYSFGIVLWEIL |
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Kinase | BMPR1B.AA | Dicty4 | 444-481 | 39 | 0.000212 | 10.78 | In-house | 231-263 (277) | Show / Hide |
Range on Protein: 444-481 Range on HMM: 231-263/277 Sequence Identity: 39% (15 aa) VCMKKLRPSFPNRWSSDECLRQMGKLMTECWAQNPASR || |||||. | | |. .|...|| .| .| VCNKKLRPPIP-----DWCPPSWKHLIQWCWDHDPQHR |
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Kinase | BMPR1B.AA | Pkinase_Tyr | 468-491 | 33 | 0.001862 | 12.33 | Pfam | 247-270 (270) | Show / Hide |
Range on Protein: 468-491 Range on HMM: 247-270/270 Sequence Identity: 33% (8 aa) KLMTECWAQNPASRLTALRVKKTL .||..||...|. | | . | DLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | BMPR1B.AA | MLK | 446-481 | 36 | 0.003242 | 7.16 | In-house | 251-281 (291) | Show / Hide |
Range on Protein: 446-481 Range on HMM: 251-281/291 Sequence Identity: 36% (13 aa) MKKLRPSFPNRWSSDECLRQMGKLMTECWAQNPASR ...||| |. | . . |||..|| |.|..| YNGLRPPIPST-----CPEHWKKLMKQCWNQDPHKR |