Gene BARK2 (Mouse)

BARK2

Species: Mouse
Alias: 4833444A01Rik, BARK2
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: AGC
Family: GRK
Subfamily: BARK

Sequence

Name Sequence Type Origin Length Description Download
BARK2.AA Protein Sugen 688 None Fasta, JSON
BARK2.NA RNA Sugen 6554 None Fasta, JSON
BARK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 263 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of BARK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RGS BARK2.AA RGS 54-174 25 9.1e-33 110.06 Pfam 1-124 (124) Show / Hide 
Range on Protein: 54-174
Range on HMM: 1-124/124
Sequence Identity: 25% (32 aa)

TFDKIF-NQKIGFLLFKDFCLNEIGEAVPQVKFYEEIKEYEKL--DNEEDRLRR-SRQMYDAYIMRELLSSTHQFSKQAVEHVQSHLSKKQVTATLFQPY
.|.... .|.||..||..|. .|  |  . ..|........|   |..|.....  |..|..||...  .. |. .....||.|..| ..|.| ..|...
SFHHLCNDQPIGRRLFRQFLESEFCEY-ENIEFWLACEDFKKMFSDSDEKMHQKDAREIYNKYIAPDSPCECHNIDHDTREHCQDNLEQAQPTPDCFDEA

IEEICESLRGDIFQKFMESDKFTRF
...|.. ...| ...|..||.. ||
QRHIYTLMEKDSYPRFLKSDYYQRF
RGS BARK2.AA RGS 54-175 21 6.5e-31 109.93 SMART 1-121 (121) Show / Hide 
Range on Protein: 54-175
Range on HMM: 1-121/121
Sequence Identity: 21% (27 aa)

TFDKIF-NQKIGFLLFKDFCLNEIGEAVPQVKFYEEIKEYEKLDNEEDRLRRSRQMYDAYIMRELLS-STHQFSKQAVEHVQSHLSKKQVTATLFQPYIE
.|.... |..|| ..|..|. .| .|... ..|.....|..|... |.|    |..|| ||. . .. . ...... .|..|..| .  .. ..|... .
SFHHLCDNDPIGRRYFREFLKQEFCEYKENLEFWLACEEFKKMED-EERRQKAREIYDKYISPNAPCEHCVNIDHHTREQCQQCLCN--PHPDCFDEAQR

EICESLRGDIFQKFMESDKFTRFC
.... ...| ...|..||...|..
HVYQLMEKDSYPRFLRSDYYKRYL
Kinase BARK2.AA BARK 191-453 91 5e-228 763.81 In-house 1-264 (264) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-264/264
Sequence Identity: 91% (242 aa)

FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNERIMLSLVSTG-DCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHGVF
||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||| |||||||||||||||||||||||||||||.||||||||||
FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVF

SEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLRGHS
||.||||||.||||||||||..||||||||||||||||.||||||||||||||||||||||||||||||||||||||.||||||||||||||.|||||||
SEQEMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLYKLLRGHS

PFRQHKTKDKHEIDRMTLTVNVQLPDAFSPELRSLLEGLLQRDVSQRLGCGGGGARELKEHIFF
|||||||||||||||||||.||.|||.||.|.|.|||||||||||.|||| |.||.|.|||.||
PFRQHKTKDKHEIDRMTLTMNVELPDSFSKEMRDLLEGLLQRDVSKRLGCMGRGAQEVKEHPFF
Kinase BARK2.AA GRK 191-453 58 1.4e-215 686.4 In-house 1-272 (272) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-272/272
Sequence Identity: 58% (159 aa)

FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHGV--
|...|..|.||||||..|....||||||.|||||||.|...|||.||||...|..|...||||||||.||..|.|.||.....|||||.|||....|.  
FRQYRVLGKGGFGEVCACQVRATGKMYACKCLDKKRIKKRKGETMALNEKQILEKVHSRDCPFIVCMAYAYETKDALCLVMTIMNGGDLHYHIYNMGNNE

--FSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKKK--PHASVGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKL
  |.|..|||||.||..|||||| ...|||||||.|||||..||||||||||||......  .|..|||||||||||||....||.|.||.|||||....
PGFDEERMRFYAAEICCGLEHMHRRRIVYRDLKPENILLDDHGHVRISDLGLACEIPEGQPMIHGRVGTHGYMAPEVLQNERAYDFSPDWWSLGCMIYEM

LRGHSPFRQHKTKDKH-EIDRMTLTVNVQLPDAFSPELRSLLEGLLQRDVSQRLGCGGG--GARELKEHIFF
..|||||||||.|.|. |.||......|..|| ||.|.....|.|||.|..||||| ||  ||.|.||| ||
IEGHSPFRQHKEKVKREEVDRRVKEDPVKYPDKFSEEAKDICEMLLQKDPEQRLGCRGGTCGAQEVKEHPFF
Kinase BARK2.AA AGC 191-453 27 2.2e-151 394.56 In-house 1-395 (395) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-395/395
Sequence Identity: 27% (111 aa)

FSVHRIIGRGGFGEVYGCRKA------DTGKMYAMKCLDKKR-VKMKQ--GETLALNE------------RIMLSLVSTGD-------CPFIVC-MTYAF
| ....||.|.||.|| .||       ||||.||||.|.||. ...|.   .  ...|            | .|....          .||||  . |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

HTPDK--LCFILDLMN---------GG-DMHYHLS---QHGVFSEKEMRFYASE-------IILGLEHMHT-CFVVYRD-LKPANILLDEYGHVRISDLG
...|.  |.|....|.         || ....||    . |.|.|.. ||||.|       |.|.||..|    ...|| ||| |||||| ||....| |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LACDFSK----------------------------------------------------KKPHASVG--THGYMAPEVLQKGTCYDSSADWFS--LGCML
|.. . .                                                    .. .  .|  |. |||||.|     |. ..|| |  |||..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

FKLLRGHSPFRQH-------------KTKDKHEIDRMTLTVNVQLP----------DAFSPELRSLLEGLLQRDVSQRLGCGGG-----GARELKEHIFF
. .| |..||. .             .. .| ...|.... .|..|          . ||||...|...||..| ..||||||.     || |.|.| .|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase BARK2.AA GRK 191-453 45 4.7e-103 348.67 In-house 1-265 (265) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-265/265
Sequence Identity: 45% (122 aa)

FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHG---
|   |. | ||||||  |    |||||| | |.|||.| ..||..||||   |  |.    .|.| . ||. | | || .. .|||||. .|.   |   
FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEQMALNEKQILEKVH---SRFVVSLAYAYETKDALCLVMTIMNGGDLKFHIYNMGENP

VFSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKKKP-HASVGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLR
 |.|.  .||| ||..|||| |   .||||.|| |||||..||.||||||||      ..    ||| |||||||..    |. | ||..||| ..    
GFDEERAIFYAAEICCGLEHLHRERIVYRDMKPENILLDDHGHIRISDLGLAVEIPEGQMIRGRVGTVGYMAPEVVKNER-YTFSPDWWGLGCLIYEMIE

GHSPFRQHKTK-DKHEIDRMTLTVNVQLP-DAFSPELRSLLEGLLQRDVSQRLGCGGGGARELKEHIFF
|.||||| | |  . |.|| ..   .. . . || | ... . ||. | .||||| ..|..|...| ||
GRSPFRQRKEKVKREEVDRRVKEDPEKYSHEKFSEEAKDICRMLLHKDPEQRLGCREEGCDEVRQHPFF
Kinase BARK2.AA Pkinase 191-453 28 1.6e-92 318.49 Pfam 1-293 (293) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLAL--NERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGG----DMHYHLS
. ..|.||.|.||.|| |.. .|||..|.|...|.. |... .|...    .||..| .   .|.|| . ..|...|..........||    | . ..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

--QHGVF--SEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHV----RISDLGLAC---DFSKKKPHASVGTHGYMAPEVLQKGTCYDSSAD
  .||.|  ||.| .||. .|. |||..| . ...|||||.|||.|. ||.    .|.| |||.     ..  ..  .|| .||||||...|. |....|
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

WFSLGCMLFKLLRGHSPFRQH----KTKDKHEIDRMTLTVNVQLPDAFS---------------------PELRSLLEGLLQRDVSQRLGCGGGGARELK
..|.||.|. .| |. ||..|    .  |. .. ....   .  .   .                     .|........|..| ..|..     |....
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQIL

EHIFF
.| .|
QHPWF
Kinase BARK2.AA RSK 194-453 34 9.9e-90 304.41 In-house 1-278 (278) Show / Hide 
Range on Protein: 194-453
Range on HMM: 1-278/278
Sequence Identity: 34% (98 aa)

HRIIGRGGFGEVYGCRKA---DTGKMYAMKCLDKKRVKMKQG-ETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHGV-
..  |.||.|.|. |||    |||. |||| |.|. .. .|     .. ||  |...  . .||||   |||.|..||  |.....||.. .||....  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERC--QQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHF

--FSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDE---YGHVRISDLGLACDF--S-KKKPHASVGTHGYMAPEVLQ---KGTCYDSSADWFSL
  |||.| .||..||.| .||.|.  ...||||| |||.|.    ||....| |... |  . ... .  ..|. |||||.|    ..  .| ..||.||
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL

GCMLFKLLRGHSPFRQHKTK-DKHEIDRMTLTVN--VQLP--DAFSPELRSLLEGLLQRDVSQRLGCGGGGARELKEHIFF
|. .. .| |..||..   . ...|| .  .. .  . .|  .  |.| ..|. ..|.|| ..||||| ..| |.|.| .|
GVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase BARK2.AA S_TKc 191-453 29 5.4e-87 296.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-231/231
Sequence Identity: 29% (82 aa)

FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNG--GDMHYHLSQHGV
. ..|.||.|.||.|| ||. .||. .|.|...            ...|. .|.     ..|.|| . ..|.. |.|........|  ||.. .. ..| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------FSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTCYDS-SADWFSLGCML
      |.| . |||. .|...||..|   ...|||||.||||||  |. |.| |||. .     .  .||  |||||||     |.  ..|| |.||.|
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

FKLLRGHSPFRQHKTKDKHEIDRMTLTVNVQLPDAFSPELRSLLEGLLQRDVSQRLGCGGGGA--RELKEHIFF
. .| |  ||.     ..  ....            |||........||.| ..|...    .  .. | | .|
YEMLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase BARK2.AA SGK 191-453 35 3.1e-82 253.67 In-house 1-283 (283) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-283/283
Sequence Identity: 35% (103 aa)

FSVHRIIGRGGFGEVYGCRKADT------------------GKMYAMKCLDKKRVK-------MKQGETLALNER-IMLSLVSTGDCPFIVCMTYAFHTP
|    .|| |.||.||  .. |.                  .|.|||| | |. .         |  . . . ||   |....    ||||   ||| |.
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMK---HPFIVNLHYAFQTK

DKLCFILDLMNGGDMHYHLSQHGVFSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLAC-DFSKKKPHASV-GTHGYMAPEVL
.|| | .| .|||.| |||   . |.| . ||||.||.. ||. |   ..|||||| |||||  ||... | ||.  .  ...   .  ||  |.|||||
WKLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVL

QKGTCYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVQLPDAFSPELRSLLEGLLQRDVSQRLGCGGGGARELKEHIFF
.| . .| . ||..||| |. .. |  ||     ..| .     .    |.|  .|.. ..|..||||.|...|||    ...| |.|.||
RKQP-HDRTVDWWCLGCVLYEMMYGLPPFYS---RNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase BARK2.AA Akt 191-453 38 7.8e-82 261.36 In-house 1-264 (264) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-264/264
Sequence Identity: 38% (104 aa)

FSVHRIIGRGGFGEVYGCRKADTGKMY-AMKCLDKKRVKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHGVF
| . ...|.| || |. ..| ||.|.| ||| | |..  .|     .. || .|  .    .|||| . |.| |.|||.|..| .|||.  |||.. ..|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN---HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRF

SEKEMRFYASEIILGLEHMHTCFVVYRD-LKPANILLDEYGHVRISDLGLAC-D-FSK-KKPHASVGTHGYMAPEVLQKGTCYDSSADWFS-LGCMLFKL
||.. |||..||||..|| | . ..||| ||| |||.|. ||... | ||.  .  .   |     ||  |.|||.|.. . .. ..|| . ||| .. .
SEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYEM

LRGHSPFRQHKTKDKHEIDRMTLTVNVQLP--DAFSPELRSLLEGLLQRDVSQRLGCGGGGARELKEHIFF
. |  ||  .. .|.|.     .. .|. |  |..||| ..|..|||..| ..||| | ..|.|.|.| .|
MCGRPPF--YN-QDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase BARK2.AA AktR 191-453 35 1.8e-74 253.71 In-house 1-268 (268) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-268/268
Sequence Identity: 35% (96 aa)

FSVHRIIGRGGFGEVYGCRKA-DTGKMYAMKCLDKKRVKMKQGETLALNERIMLS-LVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHGV
| |....|.|.||.|| ..|  |..|.|||| ..||  . .. .  ...||  .  ..   . |||| . |.| | .|| ||.. . ||.. .||.. . 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCC---NHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKK

FSEKEMRFYASEIILGLEHMHTC-FVVYRDLKPANILLDEYGHVRISDLGLAC-DFSK-K--KPHASVGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFK
|||.. |||...|.|.||. |    ..|||||| |||||| |||.|.| ||.   | . .  | .  .||. |||||...|   .. |.|| ..|. .. 
FSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYE

LLRGHSPFRQHK-TKDKHEIDRMTLTVNVQLPDAFSPELRSLLE-GLLQRDVSQRLGCGGGGARELKEHIFF
.. |. || ... . . . |.  .  . .. |  ||.....|.. .||...  .||| .  |. |.|.| .|
MVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase BARK2.AA RSK 191-453 36 4.1e-73 249.21 In-house 1-271 (271) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-271/271
Sequence Identity: 36% (103 aa)

FSVHRIIGRGGFGEVYGCRKA---DTGKMYAMKCLDKKRVKMK-QGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQH
. .|. ||.| |..|| |.|    ||.. |||| ..|. .. | .    . .|||.|. .   . ||||   |.| .  |.  |.|.| |||.  .|.  
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR--VCWEEERIILRYG---HHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQ

GVFSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEY----GHVRISDLGLACDFSKKKPHASVG-------THGYMAPEVLQKGTCYDSSADWF
..|||.| .||..|| | .|. |.  .|.|||||.|||.|.     ||..| |.|.|     |.  .  |       |  ||||||| .   .| ..||.
KMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFA-----KQLRDENGMLMTFCYTANYMAPEVLKR-QGHDQACDWW

SLGCMLFKLLRGHSPFRQHKTKDKHE--IDRMTLTV---NVQLPDAFSPELRSLLEGLLQRDVSQRLGCGGGGARELKEHIFF
|.|  ..  | |. || |.|..|  .  | |  |     .   .|  |.|  .|| ..| ||  .|||.|  |. . |.| .|
SFGVLMYEMLTGCTPF-QNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase BARK2.AA p70 191-453 34 1.4e-66 227.54 In-house 1-299 (299) Show / Hide 
Range on Protein: 191-453
Range on HMM: 1-299/299
Sequence Identity: 34% (104 aa)

FSVHRIIGRGGFGEVYGCRKAD---TGKMYAMKCLDKKRVKMKQGETLALN--------------------------ERIMLSLVSTGDCPFIVCMTYAF
|   ...|.||.| |.  ||     |||.|||| | |  .   |  |                              ||  |. |     |||.   |||
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEV---KHPFICDLHYAF

HTPDKLCFILDLMNGGDMHYHLSQHGVFSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKK--K----------PHA
.|  ||  ||. . ||   .||  ||.. |   .||.||||. ||| |.  ..|||||| |..|...|||   | ||     ..  .           | 
QTNGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHT

SVGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTV-NVQLPDAFSPELRSLLEGLLQRDVSQRLGCGGGGARELK
 .||. |||||.| . . ..   ||.|||| ..  | |  ||     |..  ||        ..||   ..| | |.  || |...||.| | . | . .
FCGTIEYMAPEILMR-CGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKT--IDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQ

EHIFF
|| ||
EHPFF
Kinase BARK2.AA S_TK_X 454-530 21 1.2e-12 49.25 SMART 1-79 (79) Show / Hide 
Range on Protein: 454-530
Range on HMM: 1-79/79
Sequence Identity: 21% (19 aa)

KGIDWQHVYL--RKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQDLYKNFPLVISERWQQEV--------VETIYDAVN
.||||...|   ....|| .|.  ||.| ...|.. ||.| |..          ..... ..|.. .|.             ...|.
RGIDWDKLYNQQKEIEPPFKPKIKEVYA-SPTDTSNFDPEFTEETPM-------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase BARK2.AA TyrKc 191-451 21 3.2e-11 -41.29 SMART 1-280 (280) Show / Hide 
Range on Protein: 191-451
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNE-RIMLSLVSTG-DCPFIVCMTYAFHTP-------DKLCFILDLMNGGDMHY
 .  ...|.| ||||| ..      . | |.| .        .   ..| ||| .|   | . | ||..  .  ..       . |. .. .| .|| . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKL---GGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

HLSQHGV-FSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKK------KPHASV----GTHG-----YMAPEVLQKG
.|  |.  .. |..  ..  |  | |. |   .. |||   |.|..| ..|.||| ||. |   .      |   ..    |...      ||||.. . 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NY

TCYDSSADWFSLGCMLFKLL-RGHSPFRQ-----HKTKD----KHEIDRMTLTVNVQLPDA----FSPELRSLLEGLLQRDVSQRLGCGGGGARELKEHI
 .. .  | .| | ... .. .| .|         . ..      . .||    |.  |       ..|. .. .   ..| ..|        .|..| .
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQIMKQCWHEDPEDRP-----TFSEIHECF
PH BARK2.AA PH 559-647 21 3e-15 57.61 Pfam 1-87 (92) Show / Hide 
Range on Protein: 559-647
Range on HMM: 1-87/92
Sequence Identity: 21% (19 aa)

CIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEG-ESRQSLLTMEQIMSVEETQIKDRKCILLRIKGGKQFVLQCESDPEFAQWLKEL
.|..|...|.|  .. .|..|.| ||.|.| .  .. .. .  . .. .  .. .  |.. |. .|. .......|.||. |. .|.. .
VIKEGWLHKKG--KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAI
PH BARK2.AA PH 559-654 18 2.4e-14 54.92 SMART 1-82 (82) Show / Hide 
Range on Protein: 559-654
Range on HMM: 1-82/82
Sequence Identity: 18% (18 aa)

CIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSLLTMEQIMSVEETQIKDRKCILLRIKGGKQFVLQCESDPEFAQWLKELTCTFNEA
 |..|...|..   . .|..|.|.||...| .  .  . .  . .. . .|.|       |. ..  ..  ...||||. |. .|.. .    ...
VIKEGWLYKKS---K-RWKKRWFVLFNDCLYYYKDK-KPKGSIPLSDC-TVRE-P-----CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN