Gene AurA (Mouse)

AurA

Species: Mouse
Alias: AurA, Stk6
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
AurA.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 251 Kinase domain by global Sugen HMM Fasta, JSON
AurA.AA Protein Sugen 395 None Fasta, JSON
AurA.NA RNA Sugen 1905 None Fasta, JSON

Protein domain

Protein domains of AurA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AurA.AA Aur 124-374 62 1.2e-243 651.34 In-house 1-257 (257) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-257/257
Sequence Identity: 62% (160 aa)

FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL--SKFDE
|.||.||||||||||||||.....|| ||||.||.|..| ..|||||||..|||||.|||||..||||||..|.|||||||| |..|.||||.   .|||
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

QRTATYITELANALSYCHSKRVIHRDIKPENLLLG-SNGELKIADFGWSVHAP-SSRRTTMCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPP
||.|.|. ...||| ||||| .|||||||||.||. .||..||.|||||||.| ..||.|.||||||.||||.||.|||.|||.|.|||||||...| ||
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FEA-HTYQETYRRIS-RVEFTFPDFVTEGARDLISRLLKHNASQRLTLAEVLEHPWI
||.  ...|||.||. .|...||......|.||||..|.|. .||.||.....||||
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase AurA.AA AGC 124-374 24 8.70000000001e-114 295.09 In-house 1-395 (395) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-395/395
Sequence Identity: 24% (99 aa)

FDIGRPLGKGKFGNVYLARER------QSKFILALKVLFKTQ---------LEKANVEHQ------LRREVEIQSHLR----------HPNILR-LYGYF
|.. ...||| || |||.|..      ... . |.||| |           .|....||       ...| .| ....          ||.| . |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

HDATR--VYLILEYAP--------LG--TVYRELQ---KLSKFDEQRTATYITE-------LANALSYCHS-KRVIHRD-IKPENLLLGSNGELKIADFG
.| ..  .|...||.|         |    .  ||   |  .|||.|.  |. |       .. || | || . .|||| .||||.|| ..| .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSVHAPSS----------------------------------------------------RRTTMCG--TLDYLPPEMIEGRMHDEKVDLWS--LGVLCY
 .   ...                                                    | .|.||  | .|..||..    ..  .| ||  ||.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFLVGMPPFEAHT----------YQETYRRIS--------RVEFTFP--------DFVTEGARDLISRLLKHNASQRLT----------LAEVLEHPWI
|.|.| ||| ...            |.. .|         .|.| ||        ..... |.|||..||. . ..||.            |. .||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase AurA.AA S_TKc 124-374 32 1.4e-101 344.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPL--GTVYRELQKLSK---
..|.|..||| || ||..|.. .. | |.|..            ..|||..| .. .|||| .||..|.| ...|...||..   |.... ..|  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRTTMCGTLDYLPPEMIEGRMHDE-KVDLWSLGVLCYEFL
   |.| ... |. ....|| ||||...||||.||||.|| .  ..||.||| . .      ||.|||..|..||..    ..  |.| ||.|.. ||.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNASQRLTLAEVLE-------HPWI
.| |||.  ..|.....|           .. |.|.|...|. . ..|.|  |.|.       |||.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AurA.AA CAMK 129-374 20 8.3e-95 305.9 In-house 1-425 (425) Show / Hide 
Range on Protein: 129-374
Range on HMM: 1-425/425
Sequence Identity: 20% (86 aa)

PLGKGKFGNVYLARERQSK------------FILALKVLFKTQLEK-------------------------ANVEHQLRREVEIQSH-------LRHPNI
 ||.| || |.|.......               | |.. |..| .                         .. ....|||.|| ..       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRLYGYFHDAT-------------------RVYLIL---EYAPLG----TVYRELQKLSK---------------FDEQRTATYITELANALSYCHSKRV
..|| .. |..                   ..|...   ||.. |     ..  ... ..               |.|. ...|.  .. |. ||||. .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENLLLGSN-----------------GELKIADFGWSVHAPSSR-------------------------RTTMCGTLDYLP-PEMIEG------
.|||.||||.|| .|                 . .||.||| . . ...                           .|.|||. | . ||...|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------RMHDEKVDLWSLGVLCYEFLVGMPPFEAH-------------TYQETYRRISRVEFTFPDF------------------------VTEGARD
        . ...|.| ||.||..|  |.| |||..              ...|....| . ...||..                        |.. ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISRLLKHNASQRLTLAEVLEHPWI
||...|. . ..|.|....|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AurA.AA Pkinase 124-374 31 7.4e-87 299.66 Pfam 1-293 (293) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-293/293
Sequence Identity: 31% (92 aa)

FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLR-REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLG----TVY-----REL
. |||..|.| || ||..... .  | |.|.. |   ..   .. .| .|..|  .|.||||.|||..|.| ...|...||.. |      .     .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGEL----KIADFGWSV---HAPSSRRTTMCGTLDYLPPEMIE-GRMHDEKVDLWS
 ... |.|.    |..... .| ||||...||||.||||.|. .||..    ||.||| .    . ..|  || |||..|..|| |  |.... ||| ||
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVLCYEFLVGMPPFEAH------TYQETYRRISRVEFTFPDFVT---------------------EGARDLISRLLKHNASQRLTLAEVLEHPWI
.|...||.| | |||  |      . .. ..|| . .. |. . .                     | ..|.|...|. . ..|.| ...|.|||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AurA.AA CAMKL 124-374 31 1.1e-84 270.22 In-house 1-297 (297) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-297/297
Sequence Identity: 31% (94 aa)

FDIGRPLGKGKFGNVYLARE-RQSKFILALKVLFKTQLE-KANVEHQ-----------LRREVEIQSHLR---HPNILRLYGYFHDATR------VYLIL
..||. |||| || | ||.  |  .   | |.. |  .  . ...             .|||..|...|.   |||| .||  . . .       .||..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAPLGT--VYRELQKL----SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNG--ELKIADFGWS-----V-HAPSSRRTTMCGTLDYL
||.. |    .  ..|      ...|  .  | . .  |..||||....||||||||.|| .||   .||.||| |     .   |    .| ||.. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEMIEG--RMHD-EKVDLWSLGVLCYEFLVGMPPFEAHTYQ-------ETYRRISRVEFTFP--DFVTEGARDLISRLLKHNASQRLTLAEVLEHPWI
.||...|  . .|  ||| ||.||. |  ..|  ||.. ||.       . |..| .  . .|   .|   .||||...|..| ..| |. ....||| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase AurA.AA MARK 124-374 35 3.1e-82 268.63 In-house 1-262 (262) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-262/262
Sequence Identity: 35% (93 aa)

FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYGYFH--DATR-VYLILEYAPLGTVYRELQKL--SK
. ... .|.| .. |.||. . ..   |.|.. |..| . .    ..||.|| ..| |||| .|. ..   . .. .|||.|||. | .|  ...    .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNG--ELKIADFGWSVHA-PSSRRTTMCGTLDYLPPEMIEGRMHD-EKVDLWSLGVLCYEFL
  |  . .. . .  |..|||||...||||||||.|. .||    ||.|||.|..  | .. .| |||. | .||.....  |  ||| |||||. |  .
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGMPPFEAHT--YQETYRRISRVEFTFPDFVTEGARDLISRLLKHNASQRLTLAEVLEHPWI
.|  ||.. |  | | |..| | ....|..|  ..|.||.|||..| ..| |. |...|||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase AurA.AA RSK 127-374 31 1e-79 271.16 In-house 1-278 (278) Show / Hide 
Range on Protein: 127-374
Range on HMM: 1-278/278
Sequence Identity: 31% (88 aa)

GRPLGKGKFGNVYLARER---QSKFILALKVLFKTQLEKANV-EHQLRREVEIQSHLR-HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK---
 . ||.| .| |.| |.    ... | | ||| |  . ....     ..|..| .. . ||.| .|.  |.. . .|||.|| . |  .. |||      
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGS---NGELKIADFGWSVH-APS--SRRTTMCGTLDYLPPEMIE---GRM-HDEKVDLWSLGV
|.| . . |. |.. |... |.. .||||.|||| |. .   .|..|. ||| .    ..  ..  | |.|..|..|||.    ..  ||. .|.|||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LCYEFLVGMPPFEA---HTYQETYRRISRVE--FTFP--DFVTEGARDLISRLLKHNASQRLT-----LAEVLEHPWI
| || |.| ||| .    . .|. .|| . .  .|.|  ..... |.|||...|. . ..||.     ..|...|||.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase AurA.AA PLK 124-374 34 4.2e-78 253.95 In-house 1-258 (258) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-258/258
Sequence Identity: 34% (90 aa)

FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL-SKFDEQ
. .|..|||| |  .| ...  .| ..| ||  |  ..| .    ...|.||.. |.||||.... .| |.  ||. |||.. ..  . . .   .. | 
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

RTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWS--VHAPSSRRTTMCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYEFLVGMP
 .  |.. ....| | |..|.||||.|. ||.| .| ..||.||| .  .  .  |. |||||  |  ||  .|    |. .|| ||||.  | .|.| |
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFEAHTYQETYRRISRVEFTFPDF--VTEGARDLISRLLKHNASQRLTLAEVLEHPWI
|||... .|||.||   ...||.   .   |.||| ..|. | ..|.|. ..|.||. 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase AurA.AA CAMK-Unique 124-374 23 9.5e-77 252.84 In-house 1-363 (363) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-363/363
Sequence Identity: 23% (86 aa)

FDIGRPLGKGKFGNVYLARERQSKFILALKVLFK-TQLEKANVE----------------HQLRREVEIQSHLRHPNILRLYGY----FHDAT-------
 . .|..|.| || || .  |  . . | |.. | |. .|....                 .|.||..|   . ||||..||..    |.|..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------RVYLILEYAPLGTVYRELQK--------------------LSKFDE--QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGE-----
        . |...||.. |... ..||                      .| |    |......|. |..| ||. ..|||.|.||... ...      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------LKIADFGWSVHAPSSRRT----TMCGTLDYLPP--------------EMIEGRMHDEKV----DLWSLGVLCYEFLVGMPPFEAHTYQ-
           .|..||| ..|  ...      |||||..|. |              |.|...  |...    |.|||||. |. |.| |||.. .   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------ETYRRISRVEF-TF-------PDFVTEGARDLISRLLKHNASQRLTLAEVLEHPWI
       |....|.  .. .|       ||.....| |.. ....   ..|....| |||.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase AurA.AA Ciliate-E2 124-374 23 2.3e-70 240.1 In-house 1-365 (365) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-365/365
Sequence Identity: 23% (89 aa)

FDIGRPLGKGKFGNVYLARERQSK-----------------------FILALKVLFKTQLEKANVEHQLRREVE----------IQSHLRHPNILRLYGY
... . .|.| || ||... .. .                       .| |.|.. | |.|  . | .. ||..          |...| ||||...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FH--DATRVYLILEYAPLGTVYRELQKL-----------SKFDEQRTATYITELAN---------------ALSYCHSKR-VIHRDIKPENLLLGSNGEL
|   | . .||..||.  |. .  ...             .|.|.  .........               || |.|||  .|||||||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGWSVHAPSSRR---------------------------------TTMCGTLDYLPPEMIEGRM---------HDEKVDLWSLGVLCYEFLVGMPP
||.||| |  .  ..                                   | |||. |..||...|           .|.|.|.|||||. ||.| | ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FEAHTYQETYRRISRVEFTFPDF------------------VTEGARDLISR----LLKHNASQRLT-LAEVLEHPWI
|        .. |   .. || .                  ... . |||..    .|. . ..|.|   ..|.|||.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase AurA.AA PLK-Unclassified 124-374 33 1.3e-68 234.22 In-house 1-264 (264) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-264/264
Sequence Identity: 33% (89 aa)

FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL-------
  .|..|||| |  .|.. .  .| |.| |.  |  |.|      |  | .|.. | |.|| . .  | |   ||. ||| | ||.   . .        
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAPS--SRRTTMCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYE
 .  |  .  | . ...|| | |..|.|||| |. |..|..| |.||.||| ..      ... | |||  |  ||  .|.   |. .|| ||.|.  | 
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

FLVGMPPFEAHTYQETYRRISRVEFTFPDFVT--EGARDLISRLLKHNASQRLTLAEVLEHPWI
.|.| ||||..  . ||..|   .. ||. ..    |.||| . |. | .||.|. . ..||. 
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase AurA.AA Pkinase_Tyr 124-267 30 1.4e-21 73.67 Pfam 1-156 (270) Show / Hide 
Range on Protein: 124-267
Range on HMM: 1-156/270
Sequence Identity: 30% (48 aa)

FDIGRPLGKGKFGNVYLARER----QSKFILALKVLFKTQLEKAN-VEHQLRREVEIQSHL-RHPNILRLYGYFH-DATR--VYLILEYAPLGTVYRELQ
  .|. ||.| ||.||... .    . |   | |.| | .  . .     . ||..| ..| .||||.||||    .     .|...||.|.|  .  |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----LSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFG
|      ... ..   . .. |....| .||. ||||.   | |...|.  ||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase AurA.AA TyrKc 124-374 23 2.3e-17 57.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 124-374
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHL--RHPNILRLYGYFHDA-------TRVYLILEYAPLGTVYRELQ
   |. || | || ||... .       ..|  |.  | |  .  ..|| .| ..|  .||||.||||.  .          .....||.|.|     |.
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KLSK-FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAPSS-------RRTTM----CGT----LDYLPPEMIEGRMHD
|  . .  .    . .  |.  .| |||..||||.   | |.|.|.  ||.||| |    .           ..    .|     .  ..|| |  ..  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKVDLWSLGVLCYEFL-VGMPPFEA-----HTYQETYRRISRVEFTFPDFV---------TEGARDLISRLLKHNASQRLTLAEVLEHPWI
.| | || ||...| .  |..| .       . || .... . .   .            ..   .....  ......| | .|.  |  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase AurA.AA Pkinase_Tyr 287-334 31 0.6187 3.79 Pfam 181-231 (270) Show / Hide 
Range on Protein: 287-334
Range on HMM: 181-231/270
Sequence Identity: 31% (16 aa)

LPPEMIEGRMHDEKVDLWSLGVLCYEFLV-GMPP-FEAHTYQETYRRI-SR
..|| |  .   .| | || |||..| .  |. | ..  . .| |..|  .
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED