Gene AMPKa1 (Mouse)

AMPKa1

Species: Mouse
Alias: C130083N04Rik, AMPKa1
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
AMPKa1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 253 Kinase domain by global Sugen HMM Fasta, JSON
AMPKa1.AA Protein Sugen 559 None Fasta, JSON
AMPKa1.NA RNA Sugen 4655 None Fasta, JSON

Protein domain

Protein domains of AMPKa1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AMPKa1.AA AMPK 27-279 71 8.8e-227 680.19 In-house 1-254 (254) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-254/254
Sequence Identity: 71% (182 aa)

YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVI-STPSDIFMVMEYVSGGELFDYICKNGRLDEK
||.|.|.|.|||||||.|.|.|||.|||.||||.|||...|.|..|.|||..||||||||||.||.|| .||.||||||||||||||||||.|.|||.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

ESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF
|..|.||||.|||.||||||.|||||||||.|||...| ||.||||||||.|||||.|.||||.|||||.|||.||.||||||||.||||||.|||.|||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWF
||...|||.|||..| .|.|..|.|.. .|.|||||||||||. |.|||.|.||
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase AMPKa1.AA CAMKL 27-279 46 2.5e-164 528.43 In-house 1-297 (297) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-297/297
Sequence Identity: 46% (140 aa)

YILGDTLGVGTFGKVKVGKH-ELTGHKVAVKILNRQKIRS-------------LDVVGKIRREIQNLKLFR---HPHIIKLYQVI-------STPSDIFM
|..|.||| |.||||| ..|  .||.|||.||....||.              .... .|||||| .|...   ||.|||||.||       .| ..|..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYL

VMEYVSGGE--LFDYICKN----GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHM--NAKIADFGLSNMMSD-----GEFLRTSCGSPN
||||.||||  |||||.|.    ||..|.| ||.|.||.|.|.|||.|..||||.||||.||| ..  |.||.|||.|||. .     |..|.|.||||.
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YAAPEVISG--RLYAGPEVDIWSSGVILYALLCGTLPFDDD--------HVPTLFKKICDGIFYTPQYLNP-SVISLLKHMLQVDPMKRAAIKDIREHEW
|.|||...|  . | ||.||||| ||||||..||.||||||        .. .|..||  | .| | .. . ....|...||||.|.||. |..|..|.|
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M
Kinase AMPKa1.AA NuaK 27-279 49 1.4e-136 361.77 In-house 1-252 (252) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-252/252
Sequence Identity: 49% (126 aa)

YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKE
| .  ||| ||.|||| .  . || .||.|   ..||..     .|||||. .    |||||. | |    . | .|||| |||||.||| . ..| |.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

SRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFD
 |..| || | | |||.| ..||||| ||.|||.  |||||||||||. .|..|| | |||| || ||.. |. | ||||| || ||.||..  ||.|||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

DDHVPTLFKKICDGIFYTPQYLNPSVIS-LLKHMLQVDPMKRAAIKDIREHEWF
 .   .| | |  | .| |.   ||. . |  .||.|.| .|| | || .| | 
GHDFKHLVKQISQGAYYEPC--KPSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase AMPKa1.AA CAMK 32-279 30 3.1e-134 435.24 In-house 1-425 (425) Show / Hide 
Range on Protein: 32-279
Range on HMM: 1-425/425
Sequence Identity: 30% (128 aa)

TLGVGTFGKVKVGKHELTG------------HKVAVKILNRQKIRS-------------------------LDVVGKIRREIQNLKL-------FRHPHI
||| |.||||| ..| .|.            .|||.||....|...                              ..||||. .|.        .||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYQVIS------------TPSD--------IFMVM---EYVSGGEL----FDYICKN---------------GRLDEKESRRLFQQILSGVDYCHRHM
||||.|.             | |.        ..|||   ||.|||||    ||||...               ||..|.| ||.|.||.|.|.||| | 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKPENVLLDAHM-----------------NAKIADFGLSNMMSD------------------------GEFLRTSCGSPNYAA-PEVISG-----
.|||||||||.||| ..                 | ||.|||..|.. .                        |. ..|.||.| |.| |||..|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------RLYAGPEVDIWSSGVILYALLCGTLPFDDD-------------HVPTLFKKICDGIFY-TPQYLNP-----------------------SVI
        . | ||..|.|| |||||..|||..||..|             . . ||.||. | ..  | |. |                       ...
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SLLKHMLQVDPMKRAAIKDIREHEWF
.|...|||||| ||. |... .|.|.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AMPKa1.AA MARK 27-279 44 2.2e-123 405.08 In-house 1-262 (262) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-262/262
Sequence Identity: 44% (116 aa)

YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVIS--TPSD-IFMVMEYVSGGELFDYICKN--GR
| .. |.| |...|||.. | .|| |||.||....|.       ...|||. .|.  ||.||||..||   |..  |...|||.|||||.||| .   ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHM--NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALL
| |.| ||.|.||.|.| |||....||||.||||.|.|...  |.||.|||.|.    |. | | ||.| |.|||..... | ||.||||| ||.||...
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

CGTLPFDDDH--VPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWF
||..|||.|     .|.|||  | .  | .. ..  .|.. .|.|.|..|. |..| .|.|.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase AMPKa1.AA BRSK 27-279 50 3.7e-117 395.53 In-house 1-254 (254) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-254/254
Sequence Identity: 50% (127 aa)

YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIR-SLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEK
|.|. ||| |. |.||.| |  || |||.|| |. |      .  |. |||  .||  |||..|.| |  .    ....|.|||||||||  | |||  |
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

ESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF
| |. |.|| |..|.|| | . |||||||| |||   | ||||||.  .  ..  | |||||| || ||||.|  | |   |.|| |||||||| | |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWF
||| .  |  |.  |.|  | .  | . .||. |. ||| ||  .|.|..| |.
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase AMPKa1.AA QIK 27-279 45 1.8e-114 386.56 In-house 1-272 (272) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-272/272
Sequence Identity: 45% (124 aa)

YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGR-----
| .. |.| | |. ||...|  |  |||.||. . .. . .   |. ||.| .|. .||||||||||. | . ...|.|| |.||.|||.||.||     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQ-KCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV
               . |.| || |.||.|.|.|||.. .|||||| ||.|||. || ||||||.||    |. | | |||| |||||.  |. | ||.|
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWF
|||| ||.||.| || |||| . ...| ...  | |  | ..     .| .||| ||| .|  |. |..| | 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase AMPKa1.AA S_TKc 27-279 39 1.3e-105 358.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-231/231
Sequence Identity: 39% (105 aa)

YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSG--GELFDYICKNGR---
| .....| |.||||. ..|  ||..||.||..           .|||||| ||  .||.|.||| |. . ....|||||..|  |.|||||.|.||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYAL
   ..| . |....||.....|||.| ..||||||||.|||   . ||.||||.  .      .| ||.|.| ||||.    | ....|.|| |.||| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIRE-------HEWF
|||  ||.  .. ..||||.           |.........||.|| ||  . .. .       |.||
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AMPKa1.AA MELK 27-279 46 1.6e-99 336.91 In-house 1-254 (254) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-254/254
Sequence Identity: 46% (119 aa)

YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKE
| . |..| | |.|||.  | ||...||.||...... .   . ... |.. || .|| || .|| .| |   ||||||| .|||.|||| .. ||.|.|
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGH--DLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

SRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMM---SDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTL
.| .|.||.| . | |     ||||||||.|.| ... |. ||||        |   | | |||| |||||.|.|. | | | |.|| |..||.|.|| |
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWF
||||| .  ..|||  |... |..| |. . ||.||||||| ||  .|.. .|.| 
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase AMPKa1.AA Pkinase 27-279 34 7.8e-99 339.44 Pfam 1-293 (293) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-293/293
Sequence Identity: 34% (103 aa)

YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIR-REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG----ELFDYIC--KN
| .| ..| |.||.|. ..|  ||..|||||.......|   . ..| .||| .| ..||.|..|| .  ....| |||||. ||    .|||||   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRL--DEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNA----KIADFGLSNM--MSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSS
|..  .|.| .. . |||.|..|||.. ..||||||||.|.| ...     ||.||||.       .. . | ||.|.|.||||| |. | ||.||.|| 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYALLCGTLPFDDD------HVPTLFKKICDGIFYTPQYLN---------------------PSVISLLKHMLQVDPMKRAAIKDIREHEWF
|.||| .||| .||...          ....| ....  . .                       .. ....| .|..|| ||  ...| .|.||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AMPKa1.AA TSSK 27-279 34 1.9e-87 287.04 In-house 1-289 (289) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-289/289
Sequence Identity: 34% (101 aa)

YILGDTLGVGTFGKVKVGKHELTGHK----------------VAVKILNRQKIRSLDVVGK-IRREIQNLKL-FRHPHIIKLYQVISTPS-DIFMVMEYV
|..| ..| |...||... .. .  |                ||.|| .|.|  . |.. | . |||| ..   .||.||..|. ..| .  |.||||| 
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKA-PTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYA

SGGELFDYICKN------GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE------FLRTSCGSPNYAAPEV
..| |..|| ..      |.|.|...|..| |. |.|.||| | ||||||| ||.||| | | |..||| ..... ..       . | |||  |||||.
EHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEI

ISGRLYAGPEVDIWSSGVILYALLCGTLPFDD--DHVPTLFKKIC-DGIFYTP---QYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWF
. |. | .  .|.|| |||||...||..||||    .... . .   .. ..    . . .. ..|..|||| .| .|. |..| .|.| 
LRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase AMPKa1.AA GIN4 72-279 45 7.7e-81 257.88 In-house 81-293 (293) Show / Hide 
Range on Protein: 72-279
Range on HMM: 81-293/293
Sequence Identity: 45% (96 aa)

IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMN-AKIADFG
| |||  .||  || ...||.|  | .|...|.||. .||||.|. . |.| |.|  . |.||. || |||   ..||||||||.|||   |  ||||||
IEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFG

LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDD--HVPTLFKKICDGIFYTPQY--LNPSVISLLKHMLQVDPMK
.  .  |.. |.|||||| |||||...|. | |   |.|| ||||.||| | ||||..   . .|  |.  | .  |    .      |.. .| ||| |
MAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEK

RAAIKDIREHEWF
|  ..|| .|   
RIKTRDILKHPLI
Kinase AMPKa1.AA Pkinase_Tyr 27-172 32 4e-22 75.54 Pfam 1-158 (270) Show / Hide 
Range on Protein: 27-172
Range on HMM: 1-158/270
Sequence Identity: 32% (51 aa)

YILGDTLGVGTFGKVKVGKHE----LTGHKVAVKILNRQKIRSLD-VVGKIRREIQNLKLF-RHPHIIKLYQVISTPSD---IFMVMEYVSGGELFDYIC
 ..| .|| | ||.|. |.       |. .||||.| ...  . .    .  ||.. .| . .||.|..|| |..  ..   |..||||. .| | ||  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----NGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS
|    ...|. |.     .|| .| .| ...  .||||   |.|..  . .||.||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase AMPKa1.AA TyrKc 27-279 25 1.2e-20 75.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLF--RHPHIIKLYQVISTP-------SDIFMVMEYVSGGELFDYIC
  ||..|| | ||.|  |.      .|||| |.  .      .  ..||.. .. .  .||.|..|| |....         ...||||...| | ||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KNGR-LDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-------EFLRTSC--GSP-----NYAAPEVISGRLYA
|... |  |.      || .| .| |.. ..||||   |.|...   .||.|||||    |.       .  |..   |.         |||.|  . . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-

GPEVDIWSSGVILYALL-CGTLPFDD-----DHVPTLFKKICDG-IFYTPQY--------LNPSVISLLKHMLQVDPMKRAAIKDIREHEWF
 .. |.|| || .. ..  |  |  .          ..... .|     |..          . . .. |   . || .|   ..|  || |
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase AMPKa1.AA GIN4 27-63 45 1.4e-10 29.59 In-house 1-37 (293) Show / Hide 
Range on Protein: 27-63
Range on HMM: 1-37/293
Sequence Identity: 45% (17 aa)

YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKI
. ||.|||.|  |||.. |.. ||.. |||.. ..||
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVISKKKI
UBA_CAMKL AMPKa1.AA UBA_CAMKL 300-339 24 6e-11 37.46 In-house 1-41 (41) Show / Hide 
Range on Protein: 300-339
Range on HMM: 1-41/41
Sequence Identity: 24% (10 aa)

DDEALKEVCEKF-ECSEEEVLSCLYNRNHQDPLAVAYHLII
|.|...|.|...  ...||. ..| |..... . ..|.|..
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL