Gene AlphaK1 (Mouse)
AlphaK1
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AlphaK1.NA | RNA | Sugen | 4795 | None | Fasta, JSON |
| AlphaK1.kin_dom | Protein Kinase Domain | None | 188 | None | Fasta, JSON |
| AlphaK1.AA | Protein | Sugen | 1231 | None | Fasta, JSON |
Protein domains of AlphaK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AlphaK1.AA | Alpha-Unclassified | 1007-1215 | 67 | 3.2e-161 | 529.72 | In-house | 1-215 (215) | Show / Hide |
Range on Protein: 1007-1215 Range on HMM: 1-215/215 Sequence Identity: 67% (146 aa) KSELWTAQETVVYLGDYLKVKKKGKQRNAFWVHYLHQEETLGRYVGKEYKERKGLRHHFTDVERQMTAQHYVTEFNKRLYEQKIPTQIFYIPSTILLILE ||||||||||.||||||| |||||.|||||||| ||||| |||||||.||| ||| |||||||||||||||||||||||||| |||||||||...|...| KSELWTAQETIVYLGDYLTVKKKGRQRNAFWVHHLHQEEILGRYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQNIPTQIFYIPPIFLIHRE DRTIKGCISVEPYILGEFVKLSNNTK----AVKNEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKDV--TTNFGKRGI |..||||||||||..|||||.||||. || ||.|..|...|.|..|...||.|.|.||||||..|.|.....||||||...|. .||.|.|.| DKNIKGCISVEPYLIGEFVKYSNNTGKEINFVKWEYEAYQYCCTYQHWTYQWTNHCDIVCDLQGWVDENDKKTWKMTDPQIHTIRQRYQGFKTNCGMRFI FYFFNNQHASCNEIC .|.|||.| ||..| DYWFNNHHVQCNHYC |
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| Kinase | AlphaK1.AA | Alpha | 1014-1215 | 31 | 7e-105 | 299.38 | In-house | 1-215 (215) | Show / Hide |
Range on Protein: 1014-1215 Range on HMM: 1-215/215 Sequence Identity: 31% (69 aa) QETVVYLGDYLKVKKKGKQRNAFWVHYLHQEETLGRYVGKEYKERKGLRHHFT-DVERQMTAQHYVTEFNKRLYEQKI----------PTQIFYIPSTIL |.| .....|. ..... .....|...|||.. ........... |.. ||.. ||||||...|.|.|||.||.||.. |...|....... QCTKIQMSSYPFMEGAMRYAMHAWDCWLHQKMVKKQHKKQWKSF-KYVWHHWIKDVERQMVCHHCVREFNQRLWEQEYTTHFNQMKPQPIKQFVHCYIYE LILEDRTIKGCISVEPYILGEFVKLSNNTKAVK---NEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHS-----VDQKDVTTN ||..........|||.|..||..|..||.. |. .........|..|.....||....||||| | |.|...|||||||. ...| ..| LIHCHNHNIKYYSVENYMEGEYQKYNNNAGWVDFLTDDNEFNQLMQAFSHWTWQYSNGQLMVVDLQ-W----GVGEWKLTDPQIHCPAKLDQGMKFGDGN FGKRGIFYFFNNQHASCNEIC .|..|.|.||...| ||..| CGYEGMFRFFYTHHVQCNHYC |
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| Kinase | AlphaK1.AA | Alpha_kinase | 1008-1215 | 30 | 5.8e-86 | 292.8 | SMART | 1-255 (255) | Show / Hide |
Range on Protein: 1008-1215 Range on HMM: 1-255/255 Sequence Identity: 30% (79 aa) SELWTAQETVVYLGDYLKVKKKGKQRNAFWVHY--------LHQEETLGRYVGKEYKERKGLRHHFT--------DVERQMTAQHYVTEFNKRLYEQKI- . .||.||| |.. . .| ||..|...|... .|..| .|..||||........|. |||.||...|...|||. .. .. DNKWTCQETCVKI-KEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQEAQ-HNPC PTQIFYIPSTILLIL------EDRTIKGC----------------ISVEPYILGEFVKLSNNTKAVKNEYKATE----------YGLAYGHFSYEFSNHR | .|..||....... .||.|... ...||.. ||||| .||. |... . |. | .|..|..|| |||. PKKIDFIPCYVFHFPRRIPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTTTSQRRTEMFEYCQAFSHWTYEWSNHQ DVVVDLQGWVTGNGKGLIYLTDPQIHSVD---QKDVTTNFGKRGIFYFFNNQHASCNEIC .|.|.||....||. |.|.||||||. | .. .|.|..|| .||.. . ||.|| MLVCDIQGVIHKNGD-LYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQ--CNQIC |
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| Kinase | AlphaK1.AA | Alpha_kinase | 1027-1215 | 29 | 1.3e-66 | 231.8 | Pfam | 1-225 (225) | Show / Hide |
Range on Protein: 1027-1215
Range on HMM: 1-225/225
Sequence Identity: 29% (68 aa)
KKKGKQRNAFWVHYL--HQEETLGRYVGKEYKE----RKG------LRHHFTDVERQMTAQHYVTEFNKRLY-EQKIPTQIFYIPSTILLILEDRTI---
.|..|..|..... ..... ..| |.||. . ..| |.. ||..|... .||..|. ....| .| .... |.. |||...
FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIKNYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIEFYDCCIVYELEDHNKPDC
------------KGCISVEPYILG-EFVKLSNNTKAV----KNEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKD--V
. ....|||| | |||| .||. | . . .. .| |. ||.|..||.. .|.|.||... |.| ..||||||||..|.. .
YQGFFSYRTDWGGKYWYMEPYIEGCEFVKYNNNYGWVYDNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGY-NNK-CYYLTDPQIHTKDGNYEMD
T--T--NFGKRGIFYFFNNQHASCNEIC
. |.|..||..|| ||| ||.||
FDEGMGNLGQEGIEKFFQNQH-KCNHIC
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| Kinase | AlphaK1.AA | VWL | 1115-1220 | 37 | 1.5e-13 | 36.85 | In-house | 106-206 (206) | Show / Hide |
Range on Protein: 1115-1220 Range on HMM: 106-206/206 Sequence Identity: 37% (42 aa) SVEPYILGEFVKLSNNTKAVKNEYKATEYGL---AYGHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQ--KDVTTNFGKRGIFYFFNNQHA .|| || |...| || . ||.. | ||.. | .|||| ||. |. ||||||| || | | | |.. || | FVENYIEGDYQKYNNNAGWCNQTDM--EYNQLSQAFSHFTWQYSQGYCMIVDLQ----GNEDGM--LTDPQIHCLDQSHKFGQGNLGYEGMLRFFMT-HQ SCNEICHRLSL ||..| .| | -CNKYCQKLQL |
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| Kinase | AlphaK1.AA | VWL | 1067-1087 | 47 | 0.063334 | 1.63 | In-house | 55-75 (206) | Show / Hide |
Range on Protein: 1067-1087 Range on HMM: 55-75/206 Sequence Identity: 47% (10 aa) DVERQMTAQHYVTEFNKRLYE |.| |. || | .|| |. | DIESQFVCQHIVNCFNDRVSE |
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