Gene ADCK3 (Mouse)

ADCK3

Species: Mouse
Alias: Cabc1, ADCK3
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-A

Sequence

Name Sequence Type Origin Length Description Download
ADCK3.kin_dom Protein Kinase Domain None 303 None Fasta, JSON
ADCK3.AA Protein Sugen 645 None Fasta, JSON
ADCK3.NA RNA Sugen 2591 None Fasta, JSON

Protein domain

Protein domains of ADCK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ADCK3.AA ABC1-A 328-524 62 3.5e-162 545.11 In-house 1-216 (216) Show / Hide 
Range on Protein: 328-524
Range on HMM: 1-216/216
Sequence Identity: 62% (135 aa)

FEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYV
|||.|||.|||||||.|..|.|||||.||||||||.||.||.||||.|.|||.|.|.|.|..|.||..|||| .||||||||. ..|||.||||.|||||
FEEMPFACASIGQVHQAVLKDGREVAVKIQYPGVAESIDSDINNLMMVMNMSGMFPKGMFLDHFIDYARRELHWECDYQREARCMQKFRQLLKDWPFFYV

PEIVDELCSPHVLTTELISGFPLDQAEGLSQEVRNEICYNILVLCLR---------------ELFEFHVMQTDPNWSNFFYDPQ----QHKVALLDFGAT
|...||.|...|||.||..|||.||..|||||.||.|||||..||||               |.||.. |||||||.|||||..    ||||.||||||.
PHVIDEYCTDRVLTMELMYGFPIDQCQGLSQEIRNYICYNIMRLCLREVEYIFLSTFIIIDFEIFEWRFMQTDPNWANFFYDKHPKTGQHKVELLDFGAS

REYDRSFTDLYIQVIR
|||...|||.|.|.|.
REYGKDFTDHYMQIIK
Kinase ADCK3.AA ABC1 315-431 44 4.3e-64 219.25 In-house 1-123 (123) Show / Hide 
Range on Protein: 315-431
Range on HMM: 1-123/123
Sequence Identity: 44% (55 aa)

SDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEG-----LFPEHLIDVLRRELTLECDYQREA
.|||  | |  . |.|.|||||||.|||.|..|.|..||.|.|.|||...|..|.||...|..|......|     .|.....|....|| .|||...||
QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKDGQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEA

AYAKKFRELLK--DHPFFYVPEIV
. |.|.|.|.|  ..||||||.|.
RNAEKCRQLFKKFHWPFFYVPRIH
Kinase ADCK3.AA ABC1 315-431 35 5.9e-44 150.06 Pfam 1-126 (126) Show / Hide 
Range on Protein: 315-431
Range on HMM: 1-126/126
Sequence Identity: 35% (45 aa)

SDLGPHWRDKLEYFEERPFAAASIGQVHLARMKG-GREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEG-----LFPEHLIDVLRRELTLECDYQRE
..||  |... . |.| |.|||||.||| || |  |.|||.|.|.|||......|..|.  ...  . .. |     .... ..|..|..|  |.|| ||
EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE

AAYAKKFRELLKDH---PFFYVPEIV
|.....|||....    |..|||...
AKNMERFRENFRHWHRQPWVYVPKVY
Kinase ADCK3.AA ABC1-B 315-431 29 1.3e-18 64.62 In-house 1-125 (125) Show / Hide 
Range on Protein: 315-431
Range on HMM: 1-125/125
Sequence Identity: 29% (38 aa)

SDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFP----------EHLIDVLRRELTLECD
.|||    |  . |.. | ||||. |||.|  ..|..|| |.|.| .  ..  |.. .  ..     . . .||            . | .   |  | |
KDLG-NIEDVFSEFDQKPIAAASLAQVHRAKLHDGETVAVKVQHPWLRKQFHYDMMMMELFV----KVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELD

YQREAAYAKKFRELLK---DHPFFYVPEIV
   ||  |.| |...|   . .| ||| | 
FYNEARNAEKCRQMFKKFKHFDFLYVPRIH