Gene ADCK1 (Mouse)
ADCK1
Sequence
Protein domains of ADCK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | ADCK1.AA | ABC1-B | 136-252 | 54 | 3.7e-73 | 249.36 | In-house | 1-125 (125) | Show / Hide |
Range on Protein: 136-252 Range on HMM: 1-125/125 Sequence Identity: 54% (69 aa) EDLGKEIHDLFLSFDDTPLGAASLAQVHKAVLHDGRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFP------DFEFMWLVDEAKKNLPLELDFLNE .||| | | | ||..|..||||||||.|.||||.|||||||||....|...|...||..| .....|| .|.|||..||..|||| ||||.|| KDLG-NIEDVFSEFDQKPIAAASLAQVHRAKLHDGETVAVKVQHPWLRKQFHYDMMMMELFVKVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELDFYNE GRNAEKVAHMLR---HFDFLKVPQIH .|||||...|.. |||||.||.|| ARNAEKCRQMFKKFKHFDFLYVPRIH |
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Kinase | ADCK1.AA | ABC1 | 136-252 | 50 | 1.3e-67 | 230.89 | In-house | 1-123 (123) | Show / Hide |
Range on Protein: 136-252 Range on HMM: 1-123/123 Sequence Identity: 50% (62 aa) EDLGKEIHDLFLSFDDTPLGAASLAQVHKAVLHDGRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFP-----DFEFMWLVDEAKKNLPLELDFLNEG .||| . | | .||..|..|||.||||.|.|.||.|||||||||.|..|...||..||..| .....|| .|..||.|||..|.||.|.||.||. QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKDGQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEA RNAEKVAHMLR--HFDFLKVPQIH |||||...... |..|..||.|| RNAEKCRQLFKKFHWPFFYVPRIH |
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Kinase | ADCK1.AA | ABC1 | 136-252 | 42 | 1.3e-62 | 212.8 | Pfam | 1-126 (126) | Show / Hide |
Range on Protein: 136-252 Range on HMM: 1-126/126 Sequence Identity: 42% (54 aa) EDLGKEIHDLFLSFDDTPLGAASLAQVHKAVLHD-GRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFPD-----FEFMWLVDEAKKNLPLELDFLNE |.||. ....| .||..|..|||.||||.|.|.| |..|||||||| |. ....|| .|.... .||..||. |..||.|||..|||| |||...| EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE GRNAEKVAHMLRHF---DFLKVPQIH ..|.|......||. ....||... AKNMERFRENFRHWHRQPWVYVPKVY |
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Kinase | ADCK1.AA | ABC1-A | 149-268 | 36 | 9.5e-18 | 58.13 | In-house | 1-120 (216) | Show / Hide |
Range on Protein: 149-268 Range on HMM: 1-120/216 Sequence Identity: 36% (45 aa) FDDTPLGAASLAQVHKAVLHDGRTVAVKVQHP--KVQAQSSKDILLMEVLVLAV--KQLFPDFEFMWLVDEAKKNLPLELDFLNEGRNAEKVAHMLRHFD | . | .|| |||.||| ||| ||||.| | . .| . |.| . .. |..|.| ..| |.. | .| | | | . | .| FEEMPFACASIGQVHQAVLKDGREVAVKIQYPGVAESIDSDINNLMMVMNMSGMFPKGMFLD----HFIDYARRELHWECDYQREARCMQKFRQLLKDWP FLKVPQIHWELSTKRVLLMEFVEG | || . |..| ||| || ..| FFYVPHVIDEYCTDRVLTMELMYG |
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Kinase | ADCK1.AA | ABC1-C | 294-316 | 65 | 3.9e-07 | 17.84 | In-house | 124-146 (307) | Show / Hide |
Range on Protein: 294-316 Range on HMM: 124-146/307 Sequence Identity: 65% (15 aa) MYSEMIFVNGFVHCDPHPGNVLV | |||| ||| | ||||.|| MLLKMIFVDNFVHADLHPGNILV |
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Kinase | ADCK1.AA | ABC1-C | 173-195 | 56 | 1.1e-05 | 13.18 | In-house | 1-23 (307) | Show / Hide |
Range on Protein: 173-195 Range on HMM: 1-23/307 Sequence Identity: 56% (13 aa) VAVKVQHPKVQAQSSKDILLMEV ||||| || . || |.||| . VAVKVLHPGLLAQVHMDLLLMKI |
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Kinase | ADCK1.AA | S_TKc | 148-426 | 12 | 3.3e-05 | -100.58 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 148-426 Range on HMM: 1-231/231 Sequence Identity: 12% (40 aa) SFDDTPLGAASLAQVHKAVLHD-GRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFPDFEFMWLVDEAKKNLPLELDFLNEGRNAEKVAHMLRHFDFL ..| . ..|.|.. .. || ||.|. . ... |.. | . . . . ... .|. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------------------------------EHIRREIQILKK--HHPNIVKLYDVFQD- KVPQIHWELSTKRVLLMEFVEG--GQVNDRAYMEKNQ-----IDVNEISCHLGKMYSEMIFV--NGFVHCDPHPGNVLVRKRPDTGKAEIVLLDHGLYQV .. . ||...| | . |. . . .. .. . . . . . . .|..|.| | |.|. . .| . | || . ----------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQ LTEEFRLDYCHLWQSLIWTDMDG---------LKQYSQRLG--AADLYPL---FACMLTARS-WDSVKQGIGQAPVSATEDSEIR---NNAACYLPE--- | | . | | | ..| . . .. ||. . .. | . . . ..| . .. .. || L-----------------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRP -ISQLLN-------HVPR . ..|. | TA-EALQDEWDIKCHPWF |