Gene ACTR2B (Mouse)

ACTR2B

Species: Mouse
Alias: Acvr2b, ACTR2B
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TKL
Family: STKR
Subfamily: STKR2

Sequence

Name Sequence Type Origin Length Description Download
ACTR2B.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 289 Kinase domain by global Sugen HMM Fasta, JSON
ACTR2B.AA Protein Sugen 536 None Fasta, JSON
ACTR2B.NA RNA Sugen 1710 None Fasta, JSON

Protein domain

Protein domains of ACTR2B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Activin_recp ACTR2B.AA Activin_recp 27-117 22 1.4e-23 79.89 Pfam 1-121 (121) Show / Hide 
Range on Protein: 27-117
Range on HMM: 1-121/121
Sequence Identity: 22% (27 aa)

RECIYYNANW------EL--ERTNQSGLERCEGEQDK------RLHCYASWRNSSGT--IELVKK----GCWLDDFNCYDR--QECVA----TEEN---P
..|...| .|          | ..... . || . ||        .||.||.....   .|....    ||| .. ||...  ..|..    ....   .
LKCYFCNGYWEYDYQICHENENNFEIPVHTCETHPDKMCFYCYDGQCYVSWEYNDDEEDTEQHQRMHMYGCWSLNENCPQCHPFMCKSYKHTHSPPHRHG

QVYFC-CCEGNFCNERFTHLP
.. .| |||...||  .|..|
HNHECWCCETDYCNRNLTPPP
Kinase ACTR2B.AA Type2 214-502 60 1.5e-217 725.19 In-house 1-315 (315) Show / Hide 
Range on Protein: 214-502
Range on HMM: 1-315/315
Sequence Identity: 60% (191 aa)

LQLLEIKARGRFGCVWKAQLMND-----FVAVKIFPLQDKQSWQSEREIFSTP-GMKHENLLQFIAAEKR---GSNLEVELWLITAFHDKGSLTDYLKGN
.||.|....||||||||||..|.     .||||||| ||||||| |..|.|.| .|.|||.||||.||||   . ....|.||.|.||.||||.|||| .
IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQH

IITWNELCHVAETMSRGLSYLHEDVP-WCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPP--------GDTH--GQVGTRRYMAPEV
.|.|.|.|..|..| |||..|||... ||....|||.|||||.||||||.|.|.|...||||||.||.|||.|        ||||  |||||||||||||
TIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPEV

LEGAINFQ--RDAFLRIDMYAMGLVLWELVSRCKAAD--GPVDEYMLPFEEEIGQH-PSLEELQEVVVHKKMRPTIKDHWLKHPGLA-QLCVTIEECWDH
||||.|||  ||||...|||||||||||.||||....  ..|.||..|||||.||| ||.|..||.||.|..||...|||..|||.. .|| |||.||||
LEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYPDDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWDH

DAEARLSAGCVEERV
||||||.|.||.||.
DAEARLTAQCVQERM
Kinase ACTR2B.AA STKR 214-502 48 9.3e-197 641.06 In-house 1-312 (312) Show / Hide 
Range on Protein: 214-502
Range on HMM: 1-312/312
Sequence Identity: 48% (151 aa)

LQLLEIKARGRFGCVWKAQLMN----DFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGS-NLEVELWLITAFHDKGSLTDYLKGNIITW
.||.|....||.|.|||.....    . ||||||| .|.|||. |.||..||.|.|||.||||||....  ......||||..| .||| |||| ..|.|
IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTIDW

NELCHVAETMSRGLSYLHEDVP-WCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHG---------QVGTRRYMAPEVLEGAI
.|.|. |..| .||..||.... |. ...|||.|||||.||||.|.|.|.|...||||||.|..|.....|.|.         ||||.||||||||.||.
HEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGAM

NFQ--RDAFLRIDMYAMGLVLWELVSRCKAAD-----GPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWL-KHPGLAQLCVTIEECWDHDAE
|||  ..||.|.||||||||.||...||....     ..|.||..||......|||.|..|.||..|..||.|...|. .||.....| |.|||||||.|
NFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDPE

ARLSAGCVEERV
|||.| ||....
ARLTALCVKKTM
Kinase ACTR2B.AA Type1 214-495 38 1.9e-118 322.38 In-house 1-283 (290) Show / Hide 
Range on Protein: 214-495
Range on HMM: 1-283/290
Sequence Identity: 38% (109 aa)

LQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCH
.|..|.  .||.| ||...   . ||||||   | .||  |.||..|  |.||| |.||||  ....   .||||| .| .||| |||. .... .... 
IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDNGSWTQLWLITDYHEHGSLYDYLNRHTLDTQQMLR

VAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPG--KPPGDTHGQVGTRRYMAPEVLEGAINFQR-DAFLRIDM
 | ..  || .|| ..  .  |  || |||||.||||.. |.... . ||.|||||..    . .  .  .|||.||||||||.  .|..  ... . |.
LAYSCACGLAHLHMEI-FGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDTDQIDIGQNPRVGTKRYMAPEVLDETMNMNCFESYKMADI

YAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSA
|..|||.||   ||.  .  |..| ||. . . . || |. ..||  .|.||.|   | .|| ....    .||| . ..||..|
YSFGLVMWEIARRCEVGG-IVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQSHPCMRHMAKLMKECWYQNPHARHTA
Kinase ACTR2B.AA TKL 220-502 25 3e-90 306.15 In-house 1-364 (364) Show / Hide 
Range on Protein: 220-502
Range on HMM: 1-364/364
Sequence Identity: 25% (96 aa)

KARGRFGCVWKAQLMN----------DFVAVKIFPLQD-------------------------KQSWQSEREIFSTPGMK---HENLLQFIAAEKRGSN-
  .|.||.|.|.....            ||||.|. ..                         ..||  ..|.. .  |.   |.|..||... ..... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

--------LEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVP-WCRGEGHKPSIAHRDFKSKNVLLKSDLT-------------
         . .|.... ....||| .||      |. .|. |  ..||..||| . | ||.    || |.||| ||||.|.....|             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT----KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-AVLADFGLAVRFEPGKPPGD-----------------THGQVGTRRYMAPEVLEGAINFQ-----------RDAFLRIDMYAMGLVLWELVSRCKAADG
 . ..||||. .... .   |                 |. |.|| |.||||||.|..|..           .... ..|.|..|.||||...||.    
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----

PVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLK-------HPGLAQLCVTIEECWDHDAEARLSAGCVEERV
   .| .|....|.|.| .|| ...|..|..||.|...|.        .. . ...  ...|||||.|.|.|. .. .| 
--PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase ACTR2B.AA Pkinase 214-502 19 1e-61 216.14 Pfam 1-293 (293) Show / Hide 
Range on Protein: 214-502
Range on HMM: 1-293/293
Sequence Identity: 19% (64 aa)

LQLLEIKARGRFGCVWKAQLMNDF--VAVKIFPLQDKQSWQSER-----EIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKG----SLTDYLK
......  .| ||||.|..  ..   |||||...... ||. ..     ||     ..|.| .... .  .    . ...... ....|    .| ||..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIS

---GNII--TWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTA----VLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEV
   .. .  ...|.....  . ||| |.|.            .| ||| |. |.|.... .      ..|||||  |.   . . ... .||..||||||
TWRHGCFYFSEWECKFYMYQILRGLEYCHSM-----------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEV

LEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGL-----------------AQ
    |.....   ..||...|..|.|....            .|| ... .|..  . ..... ....|.  | . ....                    
----IRGGQYYGPKVDMWSCGCILYEMLCGR-----------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEE

LCVTIEECWDHDAEARLSAGCVEER--V
..  |. |.. | . |..| .. .   .
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase ACTR2B.AA MLK 214-423 23 4.8e-24 80.38 In-house 1-232 (291) Show / Hide 
Range on Protein: 214-423
Range on HMM: 1-232/291
Sequence Identity: 23% (58 aa)

LQLLEIKARGRFGCVWKAQLMNDF-----VAVKIFP-------LQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLE-VELWLITAFHDKGSLTDY
.|..|.   | || |||..  |       ||||..          . ..|. |.|.     ..|.|    | . . ... .  .. ... . ..||| ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LKGN---------------IITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKS------DLTAVLADFGLAVRFEPGKPPGDT
|.|.               ...   .   |  ..||..|||.. |        . | ||| ||.|.|.        ..|.. .|||..  .        .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAP--------KPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWH-------Q

H-----GQVGTRRYMAPEVLEGAINFQRDAFLRI-DMYAMGLVLWELVSR
.     .. || ..|||||..    |. . . .  |..  |.||||...|
MCTNMMSNAGTYAWMAPEVIQQ---FRCEKYSEKCDVWSWGVVLWEMLTR
Kinase ACTR2B.AA S_TKc 214-504 19 4.3e-23 83.95 SMART 1-231 (231) Show / Hide 
Range on Protein: 214-504
Range on HMM: 1-231/231
Sequence Identity: 19% (59 aa)

LQLLEIKARGRFGCVWKAQLMN--DFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDK--GSLTDYLKGNI----
 ..|..  .| ||.|.|..  .    ||.|| .    .. ..|..| .    .|.|. ... .         .|.... . |   |.| ||.| .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---ITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQR
   ..  . ....  . ..| |.|.          .  | ||| |  |.|| .  .  ..||||| ..         . ..||. |||||||        
RFPFPE-HARFYMYQICCALEYCHS----------H-GIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL-------G

DAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEE--
  . ..|... | .|.|.....   .                       |. .. ||..              ...  |. |.. | | |..|  . .  
YGKCKCDWWSCGCILYEMLCGYPPFP-----------------------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDE

-----RVSL
        .
WDIKCHPWF
Kinase ACTR2B.AA STE 214-396 19 6.1e-19 63.61 In-house 1-236 (359) Show / Hide 
Range on Protein: 214-396
Range on HMM: 1-236/359
Sequence Identity: 19% (50 aa)

LQLLEIKARGRFGCVWKAQLM-----------------NDFVAVKIFPLQDKQS---------------WQSE---REIFSTPGMK--HENLLQFIAAEK
....|.  .| || | ||  .                 ....|.|. .|.....                . .   .||     ..  |.|  ... .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

RGSNL---EVELWLITAFHDKGSLTDYLKGNIIT---------------WNELCHVAETMSRG-LSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDL
....    . |||..  . | |||.| .| . ..                .......    .| |.|||.         |.  | ||| |. |.||    
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHS---------HH--IIHRDIKPANILL----

TAVLADFGLAVRFEP---GKPPGD--------THG-----QVGTRRYMAPEVLEG
 . |.|||.. ....   ..            | .      |||  .|||||...
-VKLCDFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQ
Kinase ACTR2B.AA LRRK 337-492 30 7e-15 49.06 In-house 183-339 (351) Show / Hide 
Range on Protein: 337-492
Range on HMM: 183-339/351
Sequence Identity: 30% (54 aa)

HKPSIAHRDFKSKNVLL-KS-----------DLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLE--GAINFQRDAFLRIDMYAMGLVLWELVS
|.|.| ||| || |.|| .|           . .| .||||.   |    ..| . | ||. ..||||..   | ...       .|.|. |..||||..
HNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTE----KVDCYSFGMILWELLT

RCKAADGPVDEYMLPFEE-EIGQHPSLEELQEVVVHKKMRPTIKDHWLKHP-----GLAQLCVTIEECWDHDAEAR
|            .||.| .   | ...|..|  . .. ||||. |   .|      . .|   |..||.|| . |
RQ----------HHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQH-YCPPCQPWHMYQDL---IQHCWQHDPKKR
Kinase ACTR2B.AA TK 214-395 12 1.9e-14 44.09 In-house 1-358 (486) Show / Hide 
Range on Protein: 214-395
Range on HMM: 1-358/486
Sequence Identity: 12% (45 aa)

LQLLEIKARGRFG---CVWKAQLMND---------------------------FVAVKIFPL--QDKQSWQSE-------------REIFSTPGMK----
..|..   .| ||    |.|... ..                            ||||.  .   . |  . .             .|      |.    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENLLQFIA-AEKRGSN-------LEVELWLITAFHDKGS----LTDYLKGN-----------------------------------------------
 |.|......   . ...       ..  ..... . ..|.    | |||. .                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------IITWNELCHVAETMSRGLSYLHED---VPWCRGEGHKPSIAHRDFKSKNVLLKSDLT-----------AV
                              ..|  .|.  .   ..|..|||.              . . |||    |.|. ....           . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEF--------IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCK

LADFGLAV-------RFEPGKPPGDTHGQVGTRR-------------------------YMAPEVLE
.|||||.        |  . .    .... ||.|                         .||||.|.
IADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLN
Kinase ACTR2B.AA C8 337-417 31 5.9e-14 44.92 In-house 140-226 (226) Show / Hide 
Range on Protein: 337-417
Range on HMM: 140-226/226
Sequence Identity: 31% (27 aa)

HKPSIAHRDFKSKNVLLKSDLTAV----LADFGLAVRFEPGKPPGDTHGQ--VGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVL
|   | ||| | .| |.. | . .    |.|||.|   .  |    ..    .||  |.|||....  |  ..   . |.. .||||
HCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase ACTR2B.AA CAMK 341-396 26 4e-13 37.93 In-house 200-294 (425) Show / Hide 
Range on Protein: 341-396
Range on HMM: 200-294/425
Sequence Identity: 26% (25 aa)

IAHRDFKSKNVLLKSD-----------------LTAVLADFGLAVRFEPGKPPG---------------------DTHGQVGTRRYMA-PEVLEG
|.||| |  |.|| ..                  .  ..|||.| .|.||.                          . ..||  ||| ||||.|
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG
Kinase ACTR2B.AA TyrKc 214-502 19 2.7e-12 -23.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 214-502
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

LQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLE-------VELWLITAFHDKGSLTDYLKGNI-
..|...  .| || |.|...    ||||      ..   .| .| .  | .|.|.......       .         |.... . ..|.| |||. .  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGV----CTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-ITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPG------KPPGDTHGQVGTR-----RYMAPEV
 ... .|.. .   ..| .|||.             . |||    |.|.....|.  .||||.   . .      |   .. .  |..     | ||||.
KLCMKDLLSFCWQIACGMEYLHSK-----------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LEGAINFQRDAFLRI-----DMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHP-----GLAQLCVTIEE
.          . ..     | .. | ..||. ...          . | ...| |  | .|. | | . ...|  ...    |       . .   ...
I----------NYGKFTTKSDVWSFGVCMWEIFTYG----------QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---PMSFVCCPDEMYQIMKQ

CWDHDAEARLSAGCVEERV
||..|.| | .   . |. 
CWHEDPEDRPTFSEIHECF
Kinase ACTR2B.AA Pkinase_Tyr 214-327 18 6.7e-07 24.0 Pfam 1-129 (270) Show / Hide 
Range on Protein: 214-327
Range on HMM: 1-129/270
Sequence Identity: 18% (25 aa)

LQLLEIKARGRFGCVWKAQLM------NDFVAVKIF----PLQD--KQSWQSEREIFSTPGM-KHENLLQFIAAEK-RGS-NLEVELWLITAFHDKGSLT
.....   .| || |.|. .       .  ||||.       ..  ...  .| .| ..  . .|.|.......   .|  |   ...... .  .|.| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQ--LGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLL

DYLKGN-----IITWNELCHVAETMSRGLSYLHE
|||. .      .|  .|.. .   ..|..||..
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLES
Kinase ACTR2B.AA CAMK 219-274 15 0.006032 4.53 In-house 1-106 (425) Show / Hide 
Range on Protein: 219-274
Range on HMM: 1-106/425
Sequence Identity: 15% (16 aa)

IKARGRFGCVWKAQLM-NDF-------------VAVKIFP-------------------------------LQDKQSWQSEREIFST---PG--MKHENL
.  ||.|| | ...   .               ||.|| .                                .|... ..| || ..    |  ..|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LQFIAA
.... .
IKLYEV
Kinase ACTR2B.AA Pkinase_Tyr 343-367 40 0.042188 7.74 Pfam 134-158 (270) Show / Hide 
Range on Protein: 343-367
Range on HMM: 134-158/270
Sequence Identity: 40% (10 aa)

HRDFKSKNVLLKSDLTAVLADFGLA
|||   .|.|.......  .|||||
HRDLAARNCLVTENNVVKICDFGLA