Gene CG9746 (Fruit Fly)
CG9746
Sequence
Protein domains of CG9746.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | CG9746.AA | VPS15 | 28-319 | 60 | 2.9e-215 | 721.44 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 28-319 Range on HMM: 1-296/296 Sequence Identity: 60% (179 aa) IAFSSNMGSTRFFKVAKAKTDEGQIVVKVFVKHDPTLPLEDHKERLEGIKKTLSLANAVNCLPFQRVELIDKAAYIMREYVKHSLYDRVSTRPFLTVLEK .....|.|||||.||.|||..||.||||||||||.|..||..|.|.|.|||.|....|.||.|.|.|...|||||.||.||||.||||.||||||...|| CHYVKNLGSTRFMKVCKAKHHEGYIVVKVFVKHDDTYSLEPYKQRIEEIKKNLMQHPAFNCCPYQKVIETDKAAYMMRQYVKHNLYDRISTRPFLQMIEK KWITFQILCALNQCHKQK-ICHGDIKLENILITSWNWILLSDFASFKPTYLPEDNPADYTYFFDTSRRRTCYIAPERFVKTLASDDDGGNGNMSVIHTDS |||.||.||||.|||||. .||||||.||||.|||||..|.|||.|||.|||||||||.|.||||||||||||||||||.....|.|..||||..||||| KWIAFQTLCALEQCHKQGNVCHGDIKSENILVTSWNWCYLTDFACFKPCYLPEDNPADFTFFFDTSRRRTCYIAPERFVSNTEQDQDSNNGNMRDIHTDS IIRLAPSYAGNTLLPAMDIFSAGCALLELWTEG-TAPFELSQLLAYRRGE-RDLVEKHLAGIENERLRNLLASMIDIH-SMNRKSAEDYLDQERGQ |.|.........|.||||||||||...||..|| ..||..|||..||.|| ....|.....|..|..|||...||... .|.|.|.|.||...|| IDRQQNPWLFGELTPAMDIFSAGCVIAELFCEGDQPPFDYSQLCKYRSGEYHPNREQIMEKIQDEHIRNLCHHMIQKDNPMKRMSCEEYLNKWRGF |
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Kinase | CG9746.AA | NuaK | 112-157 | 47 | 1.6e-15 | 36.72 | In-house | 86-131 (252) | Show / Hide |
Range on Protein: 112-157 Range on HMM: 86-131/252 Sequence Identity: 47% (22 aa) LYDRVSTRPFLTVLEKKWITFQILCALNQCHKQKICHGDIKLENIL ||| .| . |. | . . || |. ||| .||| | |||||| LYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENIL |
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Kinase | CG9746.AA | AGC | 133-169 | 41 | 1.6e-13 | 29.83 | In-house | 161-199 (395) | Show / Hide |
Range on Protein: 133-169 Range on HMM: 161-199/395 Sequence Identity: 41% (16 aa) QILCALNQCHK-QKICHGD-IKLENILITSWNWILLSDF .|..|| |. ..| | | .|.||||... | |.|| CIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDF |
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Kinase | CG9746.AA | CAMK | 106-169 | 22 | 2.3e-13 | 38.74 | In-house | 140-240 (425) | Show / Hide |
Range on Protein: 106-169 Range on HMM: 140-240/425 Sequence Identity: 22% (23 aa) EYVKH-----SLYDRVSTRPF---------------LTVLEKKWITFQILCALNQCHKQKICHGDIKLENILITSWN----------------W-ILLSD ||. |.|.. .. .| | . . ||..|.. ||...|.| |.|.||||... | . | ..| EYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIID F | F |
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Kinase | CG9746.AA | CMGC | 106-160 | 24 | 2.4e-13 | 39.3 | In-house | 135-219 (513) | Show / Hide |
Range on Protein: 106-160 Range on HMM: 135-219/513 Sequence Identity: 24% (21 aa) EYVKHSLYDRVSTRPF----------------------------LTVLEKKWITFQILCALN--QCHKQK--ICHGDIKLENILITS ||. |.||. .| ... . ...|||..|. ||... |.| |.| |||||.. EYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINH |
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Kinase | CG9746.AA | Ciliate-E2-Unclassified | 130-169 | 38 | 1.8e-12 | 39.58 | In-house | 148-191 (352) | Show / Hide |
Range on Protein: 130-169 Range on HMM: 148-191/352 Sequence Identity: 38% (17 aa) ITFQILCALNQCHKQK-ICHGDIKLENILITSWN---WILLSDF .. |||..|...|... |.| |||.||||... . | ..|| YFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDF |
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Kinase | CG9746.AA | S_TKc | 28-325 | 17 | 2.5e-12 | 3.79 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 28-325 Range on HMM: 1-231/231 Sequence Identity: 17% (54 aa) IAFSSNMGSTRFFKVAKAKTDE--GQIVVKVFVKHDPTLPLEDHKERLEGIKKTLSLANAVNCLPFQRVELIDKAAYIMREYVKH---SLYDRVSTRPF- . |. | || |.. . . .|. |... . |. . | . | . |. ||. . .|.|. |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH -----LTVLEKKWITFQILCALNQCHKQKICHGDIKLENILITSWNWILLSDF--ASFKPTYLPEDNPADYTYFFDTSRRRTC----YIAPERFVKTLAS .. . . .. ||.|||. ||...|.| |.| ||||... | ..|| | . . | |.||| . GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------------TTFCGTPWYMAPEVL------ DDDGGNGNMSVIHTDSIIRLAPSYAGNTLLP-AMDIFSAGCALLELWTEGTAPFELSQLLAYRRGERDLVEKHLAGIENERLRNLLASMIDIHSMNRKSA . . |. | || | |. . | ||. . . ... . ..... . . .| .| ---------------------------GYGKCKCDWWSCGCILYEMLC-GYPPFP-QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA EDYLDQERGQLFPEYF . | |. ..| -EALQDEWDIKCHPWF |
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Kinase | CG9746.AA | Ciliate-E2 | 133-169 | 42 | 5.7e-12 | 37.35 | In-house | 168-200 (365) | Show / Hide |
Range on Protein: 133-169 Range on HMM: 168-200/365 Sequence Identity: 42% (16 aa) QILCALNQCHKQK-ICHGDIKLENILITSWNWILLSDF .|..||. .|... |.| |||.||||. | ..|| CIILALEYLHSKNNIIHRDIKPENILF-----IKIIDF |
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Kinase | CG9746.AA | Ciliate-E1 | 32-170 | 21 | 7.7e-12 | 35.24 | In-house | 2-154 (202) | Show / Hide |
Range on Protein: 32-170 Range on HMM: 2-154/202 Sequence Identity: 21% (33 aa) SNMGSTRFFKVAKAKTDEGQIVVKVFVKHDPTLPLEDHKERLEGIKKTLSLANAVNCLPFQRVELIDKA--AYIMREYVKHSLYDRVS------------ .| .. ..|| . .. . |. .|.. .. ....| | .| . . . . .. . ||.. .| |....||.| . GNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQ -TRPFLTVLEKKWITFQILCALNQCHKQKICHGDIKLENILITSWNWILLSDFA . .| ..| |.||.. .|.. | ..|.|.||| .||||.. . ...||. QNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFG |
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Kinase | CG9746.AA | CDKL | 130-169 | 51 | 1.2e-10 | 32.6 | In-house | 103-143 (286) | Show / Hide |
Range on Protein: 130-169 Range on HMM: 103-143/286 Sequence Identity: 51% (21 aa) ITFQILCALNQCHKQKICHGDIKLENILIT-SWNWILLSDF ...||| |.|.|||... | ||| |||||| . . | || YMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDF |
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Kinase | CG9746.AA | CAMKL | 133-160 | 53 | 3e-10 | 28.76 | In-house | 135-162 (297) | Show / Hide |
Range on Protein: 133-160 Range on HMM: 135-162/297 Sequence Identity: 53% (15 aa) QILCALNQCHKQKICHGDIKLENILITS ||..|.| ||...|.| |||.||||... QIVSAVNYCHSHGIVHRDIKPENILLDE |
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Kinase | CG9746.AA | Pkinase | 106-158 | 35 | 3.9e-08 | 29.86 | Pfam | 80-141 (293) | Show / Hide |
Range on Protein: 106-158 Range on HMM: 80-141/293 Sequence Identity: 35% (22 aa) EYVKH-----SLYDRVS--TRPFL--TVLEKKWITFQILCALNQCHKQKICHGDIKLENILI ||. . .|.|..| . . . | | . |||..|. ||...|.| |.|.||||| EYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILI |
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WD40 | CG9746.AA | WD40 | 957-996 | 35 | 3.1e-11 | 34.94 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 957-996 Range on HMM: 1-39/39 Sequence Identity: 35% (14 aa) GTLVAHLHEHSESVIKLASLRPHGSLFASGSIDGTVRLWD ..... . .|. .| .| ..|...|||| |||.|.|| WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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WD40 | CG9746.AA | WD40 | 956-996 | 29 | 1.4e-08 | 35.7 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 956-996 Range on HMM: 1-46/46 Sequence Identity: 29% (14 aa) TGTLVAHLHEHSE--SVIKLASLRPH-----GSLFASGSIDGTVRLWD | ..|. .. |. .| .. . ....|||| |||.|.|| T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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WD40 | CG9746.AA | WD40 | 1006-1044 | 16 | 0.029383 | 10.03 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 1006-1044 Range on HMM: 1-46/46 Sequence Identity: 16% (8 aa) VNKSRQVYSANT---PIYALAACDSG------QSLAVGGKDGSMLMMR | ..... | ...... ...| . ||.|. ||. . T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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WD40 | CG9746.AA | WD40 | 1007-1039 | 22 | 0.744056 | 5.08 | Pfam | 1-34 (39) | Show / Hide |
Range on Protein: 1007-1039 Range on HMM: 1-34/39 Sequence Identity: 22% (8 aa) NKSRQVYSAN-TPIYALAACDS-GQSLAVGGKDGS | ... . .....| ... |. || |. ||. WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGT |
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WD40 | CG9746.AA | WD40 | 1102-1139 | 22 | 0.003965 | 15.52 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 1102-1139 Range on HMM: 1-46/46 Sequence Identity: 22% (11 aa) AWRLQNELR-HGV---ITTICADPTG------SWLATGTSGGKHICWD .. ... | .|..| .|.| ..||.| |. .|| T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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WD40 | CG9746.AA | WD40 | 1111-1139 | 32 | 0.271487 | 6.34 | Pfam | 9-39 (39) | Show / Hide |
Range on Protein: 1111-1139 Range on HMM: 9-39/39 Sequence Identity: 32% (10 aa) H-GVITTICADPT-GSWLATGTSGGKHICWD | . .| .. .| |..||.| |. || HTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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WD40 | CG9746.AA | WD40 | 1155-1184 | 30 | 0.000596 | 13.99 | Pfam | 11-39 (39) | Show / Hide |
Range on Protein: 1155-1184 Range on HMM: 11-39/39 Sequence Identity: 30% (9 aa) SWIRKVACHPTEPSYLISASQSNNEVSVWN .|.. .|.|| ...||.|.| . . .|. HWVTCCAWHPDMGHYLASGS-RDGTIRIWD |
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WD40 | CG9746.AA | WD40 | 1142-1184 | 26 | 0.001194 | 18.81 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 1142-1184 Range on HMM: 1-46/46 Sequence Identity: 26% (13 aa) FRLPIAEIK-HPADSWIRKVACHPTE-----PSYLISASQSNNEVSVWN .....| | . ||.. |. ||. |.||.|.| .. . .|. T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGT-IRIWD |
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WD40 | CG9746.AA | WD40 | 1193-1240 | 16 | 0.002457 | 12.22 | Pfam | 16-39 (39) | Show / Hide |
Range on Protein: 1193-1240 Range on HMM: 16-39/39 Sequence Identity: 16% (8 aa) VLWASPVAALSSASPSDPATTCGILSGVVDGSPFILTGSSDQRIRYWD . |. . .......|| | || || CAWHPD------------------------MGHYLASGSRDGTIRIWD |
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WD40 | CG9746.AA | WD40 | 1187-1240 | 17 | 0.039629 | 9.21 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 1187-1240 Range on HMM: 1-46/46 Sequence Identity: 17% (10 aa) TGQRQTVLW--AS--PVAALSSASPSDPATTCGILSGVVDGSPFILTGSSDQRIRYWD | . .. . .| ... . ... |.. ....|| | || || T-KCVHTFKGHTGNSWVTCVCWHPDGGSD----------DYPNYLASGS-DGTIRIWD |
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WD40 | CG9746.AA | WD40 | 1302-1342 | 26 | 4.8e-05 | 17.14 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 1302-1342 Range on HMM: 1-39/39 Sequence Identity: 26% (11 aa) SGPDMPTASHHDAITDLLMCKDKGQIYIASASRNGVIKLWK . . . | ...|.. . | .. |.||.|| | |..|. WKCKHTF-GHTHWVTCCAWHPD-MGHYLASGSRDGTIRIWD |
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WD40 | CG9746.AA | WD40 | 1301-1342 | 20 | 0.002674 | 16.6 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 1301-1342 Range on HMM: 1-46/46 Sequence Identity: 20% (10 aa) RSGPDMPTASHHD--AITDLLMCKDK----GQIYIASASRNGVIKLWK . . | . ..|.. . | . |.||.| .| |..|. T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |