CG8866

Species: Fruit Fly
Alias: UNC 51-like, SFO037, CG8866
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 85D11,

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
CG8866.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 257 Kinase domain by global Sugen HMM Fasta, JSON
CG8866.AA Protein Various 520 None Fasta, JSON

Protein domain

Protein domains of CG8866.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG8866.AA ULK 9-265 31 1.4e-113 383.62 In-house 1-324 (324) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-324/324
Sequence Identity: 31% (103 aa)

FEILEKLGAGSYA-TVYKARHKKQ---RTYHAIKYVEMSTLSQTSRE--------NLITEIRLLRELK---HKY--IVTLQDFFWDD--KNIYIVLEYCN
... ..|| ||.. .|||.|.||.     | |.| .... ... . |        .|. ||.....||   |..  || | |.|...  .||||..||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

AGNLSAFIRTKKALPEST----------CRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTRG----------ANNVSLKVADFGFAQHLKLGEINQQLK
 |.|. .| ..| ||| |          .. |..|.... .... . . | |.||||.|.. |          . |. ||.||||||.|.  .. .||. 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNNNMEQQMC

----------GSPLYMAPEIVRKH----QYD-AKADLWSIGVILYECLFGKAPYSSRTIEELL-------------LRIRKAEAITLPPNA---RISNEC
          |.||||||.|. ..    .|. .|.|.||.|.|.||.|.|| |..|. ....              . . | . |  |..     ||.||
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPEC

HDLLRRLLAHEPTARISFADFFAHPFL
.||.||.|  ... |||. ..|.||..
KDLIRRMLQYDEKDRISWEEIFNHPWF

Kinase CG8866.AA ULK 9-265 30 4.3e-109 368.72 In-house 1-329 (329) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-329/329
Sequence Identity: 30% (101 aa)

FEILEKLGAGSYATVYKARHKKQR----TYHAIKYVEMSTLSQTSREN--------LITEIRLLRELK----HKY----IVTLQDFFWDD--KNIYIVLE
... ..|| ||...|||.|.||.      . |.| .. ....| . |.        |. ||.....||    ||.    || | |.|...  .||||..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCNAGNLSAFIRTKKALPEST----------CRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTRG----------ANNVSLKVADFGFAQHLKLG----
||| |.|. .| ..| |||.|          .. |..|.... .... . . | |.|||| |.. |          . |. ||.||||||.|.  .    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNDNMEQ

EINQQLK------GSPLYMAPEIVRKH----QYD-AKADLWSIGVILYECLFGKAPYSSRTIEELL-LRIRKAEAI---------TLPPNAR-------I
....  .      |.||||||.|. ..    .|. .|.|.||.|.|.||.|.|| |...  ....  . |.|   .         . |.. .       |
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SNECHDLLRRLLAHEPTARISFADFFAHPFL
|.||.||.||.|  ... |||. ..|.||..
SPECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase CG8866.AA S_TKc 9-265 31 5.3e-89 302.9 SMART 1-231 (231) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

FEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLRELKHKYIVTLQDFFWDDKNIYIVLEYCNA--GNLSAFIRTKKA----
.|||.|.| |....|||.||||   . ||| .          |... ||..|.. .|..||.| |.| | ...|.|.|||.   |.|  .|. ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTRGANNVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDA-KADLWSIGVILY
  .|| ..|....|.. |..|.  . . | ||||.|.||..      .|..|||.| .|        . |.| |||||..   .|.  |.| ||.|.|||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ECLFGKAPYSSRTIEELLLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTARISFADFFA-------HPFL
|.| |. |..  ...... .|.             | |. |..|..|  .|. |..  . ..       ||..
EMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase CG8866.AA CAMK 14-265 21 1.4e-80 259.24 In-house 1-425 (425) Show / Hide
Range on Protein: 14-265
Range on HMM: 1-425/425
Sequence Identity: 21% (92 aa)

KLGAGSYATVYKARHKKQR------------TYHAIKYVEMSTLS--------------------------QTSRENLITEIRLLRE-------LKHKYI
.|| ||...|....||.              .  ||| .. . |.                          . .|.|.  ||....        |.|. |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VTLQDFFWD-------------------DKNIYIVL---EYCNAG----NLSAFIRTK---------------KALPESTCRYFLRQLAAAVQYMRANDV
. | ... |                   ||..|.|.   |||  |     |  .|. .               . ..|. .|.. ||.. ||.|.  ...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHFDLKPQNLLL-TRGANNV-------------SLKVADFGFAQHLKLGEINQ------------------------QLKGSPLYMA-PEIVRKHQ----
 | |||| |.|| ... ..               .|..|||||.... || |                            |.| ||| ||.... .    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YDAKADLWSIGVILYECLFGKAPYSSR-------------TIEELLLRIRKAEAITLPP-------------NARISNE--------CHD
          |. |.| ||.||||| .| |. |. .              ...||. .|.|..    ||               .||.|        | |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLRRLLAHEPTARISFADFFAHPFL
|.|..|  .|. |.. ..  .||..
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase CG8866.AA Pkinase 9-265 27 2.4e-76 264.75 Pfam 1-293 (293) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

FEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLIT--EIRLLRELKHKYIVTLQDFFWDDKNIYIVLEYCNAG----NLSAFIR--TK
..|..|.|.||...|||..||. .   |.| .. .. .   .....   ||.....|.|..||.| |.| |...||.|.|||. |     |...|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KAL--PESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLT-RGANNVSLKVADFGFAQH--LKLGEINQQLKGSPLYMAPEIVR-KHQYDAKADLWSI
...  .| .|. ...|.. ...|. .. . | ||||.|.|.  .| .. ..|..|||.| .  .  .. .. . |.| |||||..|    |. |.| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYECLFGKAPYSSR------TIEELLLRIRKAEAITLPPNA------------------RISNECHDLLRRLLAHEPTARISFADFFAHPFL
|.|||| |.|. |....      .  ... ||....     |.                   ..| || |.....|.  |. |..... . ||..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase CG8866.AA Ciliate-E2 9-265 22 5.1e-74 252.23 In-house 1-365 (365) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

FEILEKLGAGSYATVYKARHKKQRT------------------YHAIKYVEMSTLSQTSRENLITEIRLLRELK----------------HKYIVTLQDF
.....|.| |....|||....|..                   . .||...| ....   |..  ||...||..                |..|. . ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FW--DDKNIYIVLEYCNAGNLSAFIR---TK--------KALPESTCRYFLRQLAA---------------AVQYMRAND-VSHFDLKPQNLLLTRGANN
|   ||.|||.|.|||. |.|  .|.   .|        | . |  ..|. .|..                |..|.  .  . | |.||.|.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VSLKVADFGFAQHLKLGEINQQ--------------------------------LKGSPLYMAPEIVR---------KHQYDAKADLWSIGVILYECLFG
  .|..|||... ..  ..|..                                . |.| ||||||..         ...|| |.|.||.||||||.|||
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

KAPYSSRTIEELLLRIRKAEAITLPPN----------------ARISNECHDLLRR----LLAHEPTARIS-FADFFAHPFL
| |.         ... |   | .|..                  .|.|| ||...    .|  .|  ||. . . . ||..
KPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase CG8866.AA CAMKL 9-265 28 3.3e-72 229.69 In-house 1-297 (297) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-297/297
Sequence Identity: 28% (85 aa)

FEILEKLGAGSYATVYKARH-KKQRTYHAIKYVE--MSTLSQTSREN-----------LITEIRLLRELK---HKYIVTLQDFFWDDKN------IYIVL
..|.. || ||...|  |.| . ...  ||| ..    .. . .. |           .  ||.... |.   |. |. | . . ....      ||.|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCNAGN--LSAFIRTK----KALPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLT-RGANNVSLKVADFGFAQHLK-L----GEINQQLKGSPL
|||  |.  |  .|. .    . .||. .| . ||. .||.|.  ... | |.|| |.||. .| |   .|..||||. . .      |.      ||| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YMAPEIVRK-HQ-YD-AKADLWSIGVILYECLFGKAPYSSRTI-------EELLLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTARISFADFFAHP
||||||. . .. ||  |.| ||.|||||  ..|. |    |.         .|... .      |.  ..| .|.||.|..| . |. |..  .   ||
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

FL
..
WM

Kinase CG8866.AA Ciliate-E2a 9-265 30 2.9e-70 206.03 In-house 1-275 (275) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-275/275
Sequence Identity: 30% (85 aa)

FEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTS--RENLITEIRLLRELKHKYIVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPES
.... |.| |... ||.|.||..    |.|...   ..|.   .|... || ..|.|.|. |  | ... |..|.|.|.|||. | |   |. .| . | 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--TCRYFLRQLA-AAVQYMRANDVSHFDLKPQNLLLT-RGANN---VSLKVADFGFAQHL--KLGEINQQLKGSPLYMAPEIVRKHQ------YDAKADL
    . ...||   ...||  . . | ||||.|.|.. . .|.     .|..|||.|.    . ..   |  |.| |.|||.    .      || | |.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSIGVILYECLFGKAPYSSRTIEELLLRIRKAEAI-TLPP-NARISNECHDLLRRLLAHEPTARISFADFFAHPFL
||.|||.|  |.|| |.  .| .| |  ..| .     |     .|.|| ||....|   |  ||. ..   ||. 
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase CG8866.AA Ciliate-E2-Unclassified 9-265 23 8e-67 228.31 In-house 1-352 (352) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-352/352
Sequence Identity: 23% (82 aa)

FEILEKLGAGSYATVYKARHKKQRTYH-----AIKYVEMSTLSQTS-----RENLITEIR--------------LLRELKHKYIVTLQDFFWDDKNIYIV
..|....| |....|||..||||  .      ..|. . . ... .     .| .. ...              .|. ..| .|| . . | |..|||||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LEYCNAGNLSAFIRTK-----------------KALPESTCR-----YFLRQLAAAVQYMRAND-VSHFDLKPQNLLLTRGANNVSLKVADFGFAQHLKL
.|||. |.|. .|. .                 | ..|  ..     ....|.  . .|.  .  . | |.||.|.|.. . .|  .|..|||.. ... 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

G----------------EINQQLKGSPLYM----APEIVRKHQYD----AKADLWSIGVILYECLFGKAPYSSRTIEE---------------LLLRIRK
                 .. ..  |.| ||    |||. ....||     |.| || ||||||.|||. |..... |.                |... |
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

AEAITLPPNA------RISNECHDLLR----RLLAHEPTARISFADFFAHPFL
.  |  |.        ..|.|. |...    ..|   |  ||.| . . ||..
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase CG8866.AA MARK 9-265 32 5e-63 204.91 In-house 1-262 (262) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-262/262
Sequence Identity: 32% (87 aa)

FEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQ-TSRENLITEIRLLRELKHKYIVTLQDFFW--DDKN-IYIVLEYCNAGNLSAFIRTK--KA
...|  .| ||||.|..|.||. ..  ||| .|   |.   ...|.  ||.... |.|..|. | . .   . .. ||...||.  |.|  .|. .    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTRGANNV--SLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYD-AKADLWSIGVILY
|.|. .| . ||.  ||.|.  ... | |.||.|.|.     |     | .||||. . . |.      |.| ||||||. |  ||  |.| || ||.||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILI---DENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLY

ECLFGKAPYSSRT--IEELLLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTARISFADFFAHPFL
  . |. |.   |  ..||  .|.. .    |..  .| ||..|..||| . |  |..  .   ||..
FMVCGYFPFDGDTQDYKELYKKILRGKYD-IPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase CG8866.AA STE 9-265 20 8e-63 215.02 In-house 1-359 (359) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-359/359
Sequence Identity: 20% (74 aa)

FEILEKLGAGSYATVYKARHKK---------------QRTYHAIKYVEMSTLSQ---------------TSRENLITEIRLLRELK--HKYIVTLQDFFW
.|..||.| |.. |||||...|               . .. ||| ..... ..               . ..... ||.......  |..||.  . . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DD-------KNIYIVLEYCNAGNLSAFIRTK--------------KALPESTCRYFLRQLAAA-VQYMRANDVSHFDLKPQNLLLTRGANNVSLKVADFG
..        ...|..||...| |. .|..|              . .|||  .|..||.  .  .|   . . | |.||.| ||         | .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDFG

FAQHLKL-----------------GEINQQLKGSPLYMAPEIVRK------HQYDAKADLWSIGVILYECLFGKAPYSSRTIEELLLRIRKA--------
..  |                   .. .. . |.| .||||....      ..||.|.| ||.|  . | . || |..  .  . ...| .         
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

-------EAITLPP-----------------NARISNECHDLLRRLLAHEPTARISFADFFA--HPFL
       .  .||.                   . | |..| ... |  .|  | .  .     |||.
QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase CG8866.AA RSK 11-265 26 1.6e-55 190.79 In-house 1-278 (278) Show / Hide
Range on Protein: 11-265
Range on HMM: 1-278/278
Sequence Identity: 26% (73 aa)

ILEK--LGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSR--ENLITEIRLLRELK-HKYIVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKA---
. ..  .| |.. .. | .|...... | | .. ... |. .  .   ||.. | . . |. |||| . | ... .|...|||. | |   ....|    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTRGANN-VSLKVADFGFAQHLKLGEINQQLK---GSPLYMAPEIVR---KHQ-YDAKADLWSI
. |..... ..... ||...   .. | |||| | |..    |  ..|. ||||.  ... . ||...   ..  |||||...   .   .|. .|.|| 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDH-NQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL

GVILYECLFGKAPYSS---RTIEELLLRIRKAE-AITLPPNARISNECHDLLRRLLAHEPTARIS-----FADFFAHPFL
||..|| |.|. |. .    . .|.. ||.|..   |.| .. .|.|. ||.|..|  .|  |..      ..  .||..
GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase CG8866.AA TyrKc 9-265 22 1e-17 63.62 SMART 1-280 (280) Show / Hide
Range on Protein: 9-265
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLREL--KHKYIVTLQDFFWDD-------KNIYIVLEYCNAGNLSAFIRT
 . ..||| | . .|||.. |   .  |.| .  ..     || .. |.|....|  .|. || |     ..       . ..||.||.  |.|  ..| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KKA-LPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTRGANNVSLKVADFGFAQHLKLG--------EINQ----QLKG-SPL-YMAPEIVRKHQ
..  |. ..  .|  | |.  .|   . . | ||   | |....      |..||| .  .. .         . .    . |.  |.  ||||  ... 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDAKADLWSIGVILYECL-FGKAPYSS-----RTIEELLLRIRKAEAITLPPN------ARISNECHDLLRRLLAHEPTARISFADFFAHPFL
.  | | || || ..| . .|. ||.       . .|.. .... .    |||       . . | ... ..  ...|  | .|..   | ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase CG8866.AA Pkinase_Tyr 9-222 27 2.7e-17 59.2 Pfam 1-231 (270) Show / Hide
Range on Protein: 9-222
Range on HMM: 1-231/270
Sequence Identity: 27% (64 aa)

FEILEKLGAGSYATVYKARHK----KQRTYHAIKYVEMSTLSQTS--RENLITEIRLLREL-KHKYIVTLQDFFW-DDKN--IYIVLEYCNAGNLSAFIR
 ....|||.|.. .|||.. |    ....  |.| .   . ..    || .. |......| .|. || |      ...   ||||.||.  |.|  . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----KKALPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTRGANNVSLKVADFGFAQHLKLGEIN-QQLKGSPL---YMAPEIVRKHQYDAKAD
.    |..|. ..   . .| |.. .|  ..   | ||   | |.|.  ||   |..||| |  .   .   .. .|..|    ||||  .   .  | |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

LWSIGVILYECLF-GKAP-YSSRTIEELLLRI-RK
 || || ..| .  |. | |   . ||.. .| ..
VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED

MIT CG8866.AA MIT 272-350 31 1.7e-25 91.93 SMART 1-81 (81) Show / Hide
Range on Protein: 272-350
Range on HMM: 1-81/81
Sequence Identity: 31% (26 aa)

TEHTLQKAIDLVTQACAYDE--KHNYKEAYYLYCSALQYFVPLITEE-TDATKRLALRNRALSYTKRAEEIKNCIIEDEYRM
. ...||||...|||...||  ...| .|...|.....|..  | .| .| ..| |..... .| .|.||||||. .  . .
QRDYYQKAIEYITQAVKADEDEWGDYEQAIEHYQKGIDYLMQGIKYEKPDEKRRHAIWAKCREYLDRMEEIKNCHDW-RLCP

MIT CG8866.AA MIT 275-343 42 1e-23 85.53 Pfam 1-71 (71) Show / Hide
Range on Protein: 275-343
Range on HMM: 1-71/71
Sequence Identity: 42% (30 aa)

TLQKAIDLVTQACAYDE-KHNYKEAYYLYCSALQYFVPLITEETDATKRLA-LRNRALSYTKRAEEIKNCI
 |||||.||..|  .|| ..|| ||. .|..|..||...|  | ....| | || .   | .|||.||...
YLQKAIELVKKAVEADEDAGNYEEAIQCYQEAIEYFMQAIKYEPNPKWREARLRQKMQEYMDRAEQIKEHL

MIT CG8866.AA MIT 399-474 23 4.8e-12 44.87 Pfam 1-71 (71) Show / Hide
Range on Protein: 399-474
Range on HMM: 1-71/71
Sequence Identity: 23% (18 aa)

ALSNSSPSMKTGLEIGR-KGELYLYERKLDAALESYTSALGILVPFVNNEPKGERRNL-LLQQLEFWMKEAESIKSIL
.|..     |...|. . .|       . ..|.. |..|..........||  ..|.. | |  . .|. || ||..|
YLQKAIELVKKAVEADEDAG-------NYEEAIQCYQEAIEYFMQAIKYEPNPKWREARLRQKMQEYMDRAEQIKEHL