Gene Cad96Ca (Fruit Fly)

Cad96Ca

Species: Fruit Fly
Alias: FGFR1-like, Cad96Ca, CG10244, SFO173, DCad96Ca, DmHD-14, CT28779, CG10239, HD-14
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 96C4--5

Classification

Group: TK
Family: TK-Unique

Sequence

Name Sequence Type Origin Length Description Download
Cad96Ca.AA Protein Various 773 None Fasta, JSON
Cad96Ca.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 271 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of Cad96Ca.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
CA Cad96Ca.AA CA 79-166 14 3e-06 28.22 SMART 1-121 (121) Show / Hide 
Range on Protein: 79-166
Range on HMM: 1-121/121
Sequence Identity: 14% (20 aa)

VRAEDPDGD------D------LIFGIEPRFSLPGGENDASPPEKIPFQIDRETG-----------VVTLNESLAGRAG---------QNFLIYITVTDG
|.| ||| .      .      . . |..                 .|.||..||           ..|....|   ..         ... . ...|||
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-----------------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDG

S------------------YTAKNEVFINILGERENSS
                    ..  .| |..| . .|  
GGPPPPDSHPTRKFQQNPPLSSTCTVTIHVLDVNDNPP
Kinase Cad96Ca.AA TK-Unique 470-741 46 1.9e-153 516.11 In-house 1-294 (294) Show / Hide 
Range on Protein: 470-741
Range on HMM: 1-294/294
Sequence Identity: 46% (138 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGIT-TVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKD-PTFVILEYVNRGKLQTYLRSSR
|......||||||||||.|...|..... .  ||||.||..||..|..|.|.|...||.| .|.|.|..|||||..| |.. |.||. .| ||.|||..|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

AE--RH--YGNTH--------GKSNV-LTSCDLTSFMYQVAKGMDYLTS--RGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERK-SEGKLPI
 .  .|  |||          ....  ....|| .|..|.|.|| || |  ..|.||||.|||.|.|.|..||..|||.|||| | . |... |.|..||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWMATESLY--DNIF-SVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHC-RRELYNIMYYCWSHDPQERPLFAEIIQML
|||| |||.  .... . |||.||||.|||||.|||..||||....|.|...|||||...|||| ..|.||.|..||...|.||| |..|...|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase Cad96Ca.AA TyrKc 470-741 38 9.40000000001e-128 431.64 SMART 1-280 (280) Show / Hide 
Range on Protein: 470-741
Range on HMM: 1-280/280
Sequence Identity: 38% (118 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSL-EPHINVVHLLGCCTDK-------DPTFVILEYVNRGKLQT
...  .|||||||.|......        ..||||.|||.|    |.|...|...|..|   | |.| |.|.||..       .| ....||.  | |. 
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

YLRSSRAERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITS-------KIYERKS--EGK--LP
|||..| .            |.  || ||..|.|.||.|| |...|||||||||.|....||.|..||| .||.          . |  |.   ||  ||
YLRKHRPK------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP

IRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPG-----ISAADVMRKVRDGYRLEKPEH--------CRRELYNIMYYCWSHDPQERPLFAEI
||||| |.. ...|. |||.||||..|||| |.| .||||     .|...|...|..|||...|..        |  |.|.||  || .|| .|| |.||
IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

IQML
.. .
HECF
Kinase Cad96Ca.AA Pkinase_Tyr 470-741 42 1.5e-126 429.19 Pfam 1-270 (270) Show / Hide 
Range on Protein: 470-741
Range on HMM: 1-270/270
Sequence Identity: 42% (120 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVD--RKDLLSELEVMKSLEPHINVVHLLGCCT-DKDP--TFVILEYVNRGKLQTYLR
..|   |||||||.|......   . .. ..||||.|||.|.. .  |.|...|...||.|  | |.| |.|.|| ...|   ....||.  | | .|||
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

SSRAERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIY-ERKSEGKLPIRWMATESLYDNI
. |            . ||  || .. .|.||||.|| |...|||||||||.|.|.....|..||| |||.     |   ...|||||.||| |.. ...
KHR---------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK

FSVKSDIWSFGILMWEIVTLGSTP-YPGISAADVMRKV-RDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQML
|..|||.||||.|||||.|.| .| |||.| ..|.... .||||...||.|  |.|..|  || .||..|| |.||...|
FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Cad96Ca.AA FGFR 470-741 42 4.90000000001e-120 405.08 In-house 1-293 (293) Show / Hide 
Range on Protein: 470-741
Range on HMM: 1-293/293
Sequence Identity: 42% (125 aa)

LKFFNILGEGAFGQVWRCEATNINGN--EGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSR
|    .||||.|||||. ||  |  .  |  .||||| ||...|. |  || ||.|.||    |.|.. ||||||   | .|| ||  .| |  .||. |
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRARR

---AERHYGNT-------HGKSNV--------LTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKL
    .. .          .  . .        ||. ||.|. ||||.||.|| || .|||||||||.|.|||.  |..||| |||.     |  ...| |
PPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGRL

PIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGIS-AADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQML
|| ||| |.| |... ..||.||.|.|.||| |.| .|||.|  . .     . |.|.|||..|  |.| .|  ||   |..|| |....  |
PIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase Cad96Ca.AA TK 470-741 24 6.8e-119 400.43 In-house 1-486 (486) Show / Hide 
Range on Protein: 470-741
Range on HMM: 1-486/486
Sequence Identity: 24% (121 aa)

LKFFNILGEGAFG---QVWRCEATNIN--------------------GNEGITTVAVKTLKE--SATEVDRKD--------------LLSELEVMKS-LE
... . ||||.||   .|...|. ..|                    ...| |.||||.|||  .... ...|              ...|...|.. | 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

PHINVVHLLGCCTDK------------DPTFVILEYVNRGK----LQTYLRSSRAERHYGNTHGK-----------------------------------
 | |.|.|.|.||..             |  ...||.. |     |..|||..| ...    ..                                    
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------SNVLTSCDLTS-------------------FMYQVAKGMDYLTSR------GIIHRDLAARNILITDDHT-----------CKVADFG----
        .. ||  || .                   ...|.|.|| || |.      ...||||||||.|......           ||.||||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----FARDVITSKIYERKS------------------------EGKLPIRWMATESLYDNI---------FSVKSDIWSFGILMWEIVTLGSTPYPG-IS
     |||.  .. | |||                         ||||||||| |.| |..         |. |||.||||.|||||.|.| .||.| .|
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

A---------ADVMRKVRDG--------------YRLEKPEHCR--------------RELYNIMYYCWSHDPQERPLFAEIIQML
          ..||...|.|              .|...|.||                |.| .|  ||..||..|| |... ..|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Cad96Ca.AA Ret 470-743 40 1.4e-109 370.37 In-house 1-293 (293) Show / Hide 
Range on Protein: 470-743
Range on HMM: 1-293/293
Sequence Identity: 40% (120 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKES-ATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKD--PTFVILEYVNRGKLQTYLRSS
| .   |||| |||| .  |. | |  |.|||||| ||.  |. .  .|||||... | .  | .|. |.| |. .|  || .| ||   | |  .|| |
LQLDDTLGEGHFGQVVKAQAFHIRGHPGYTTVAVKMLKRNTANSSEYHDLLSEFQLLKQVN-HPHVIKLYGACIQDDPFPTCLIVEYCKYGCLREFLRLS

RAE-----------RHYGNTHGK-SNVLT-----SCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKL
|                .  |     |..       .. ||  |. ||| || .  ..||||||||.|. .   ||. |||  |||     |...| ...
RKIGPYYEYSIGNRNCSIVDHPDGKDVINRFDIGMKMIISFAWQICKGMHYLSEMKLVHRDLAARNVLVAEGRICKISDFGLTRDVYEDDSYVKRSKDRI

PIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDK
|. ||| |||||... .|||.||||.|.|||||.|  ||||| .       ..||| . || |  |.| ||  ||   |  || |. | . . |
PVKWMAIESLYDHVYTTKSDVWSFGVLCWEIVTMGANPYPGIPPERLWQLLKTGYRMDRPENCSEEMYRIMRQCWKQEPDKRPVFKFISKDFEK
Kinase Cad96Ca.AA UTK 470-741 34 1.2e-99 337.34 In-house 1-296 (296) Show / Hide 
Range on Protein: 470-741
Range on HMM: 1-296/296
Sequence Identity: 34% (105 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLK-ESATEVDRK---DLLSELE---VMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTY
... . ||.||||.| ....|.... ..   ||||... ..... ..    |.. |     .|| .. | ||. |.| ||.  |. ...||  .|.|..|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRSSRAERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDH-------TCKVADFG---FARDVIT--------SKIYERK
||..| .       .    ||...........| || || |.|..||||||||.|.....       .||.||||   ..|.| |        .  |...
LRRHRPTPP-----ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMA

S-EGKLPIRWMATESLYDN-IFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDG--YRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQM
.  ...|||||| |.|...  |. |||.||||...|||.| |..||||.|...|   |..|  ||...|..| ...|..|  ||  |||||| | .. | 
QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQ

L
.
M
Kinase Cad96Ca.AA Src 470-741 40 8.3e-99 334.56 In-house 1-255 (255) Show / Hide 
Range on Protein: 470-741
Range on HMM: 1-255/255
Sequence Identity: 40% (110 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAE
.|.   ||.| || ||           | | |||||||.     . ...| | ..||.|  | ..|.|.  |....| . . || ..| |..||.     
IKLCRKLGQGQFGEVWMGY------WNGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLR-HEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK----

RHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVIT--SKIYERKSEGKLPIRWMATESLYDNIFSVK
       |.   |   .| ..  |||.||.|| |. .|||||||||.|. ..  ||||||| || .|     .|. ... |.||.|.| | .  . |..|
------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIK

SDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYN-IMYYCWSHDPQERPLFAEIIQML
|| ||||||..|||| | .|||| . ..|...|  |||. .|..|  |||. ||  ||  ||..|| |. . . |
SDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Cad96Ca.AA Tie 478-741 41 1.8e-96 294.13 In-house 1-267 (267) Show / Hide 
Range on Protein: 478-741
Range on HMM: 1-267/267
Sequence Identity: 41% (113 aa)

EGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSR---AERHYGN
|| |||| .     |    .   ||.|..|| | | |..|   |||||  .  | |.. |.| | ..   .| .||   | |  .||.||   ..  .  
EGNFGQVMKAM---IKKDGLKMEVAIKMMKEYASEDDHRDFMGELEVMCKVGHHPNIINLVGACEHRGYLYVAIEYAPYGNLLDFLRKSRVIETDPAFAR

THGK------SNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKLPIRWMATESLYDNIFSVKS
 |.       .  |.|  .  |   ||.||.||. ...|||||||||||. .   ||.|||| .|      .| .|  |.||.|||| |||   ..  ||
EHTTRFKVNVASTLSSQQILHFAADVARGMQYLSQKQCIHRDLAARNILVCENYVCKIADFGLSR---GDEVYVKKTMGRLPVRWMAIESLNYSVYTTKS

DIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQML
|.||.|.|.||||.|| ||| |.  |..  |.  |||.|.|  |  |.|..|  || . | ||| ||.|.  |
DVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYDLMRQCWRDRPYERPPFAQIAVQL
Kinase Cad96Ca.AA InsR 470-743 36 4e-95 319.95 In-house 1-278 (278) Show / Hide 
Range on Protein: 470-743
Range on HMM: 1-278/278
Sequence Identity: 36% (103 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGIT--TVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSR
.     .|.|.|| |    | .|  .|. .   .|.||..|.|.  .| . |.| .|||  . | .|| ||| |.   |. |. |   .| | .|||| |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCH-HVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRR

AERH--YGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKLPIRWMATESLYDNIFS
 |     .   ..  | .  ....   ... || || ..  .|||||.|| .. .| |.|..||| .||.  .  | .   |.||.|||| ||| | .|.
PEEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFT

VKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKV-RDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDK
 .||.||||...||.||||. || | | . | . . .||  |..|| |   .. .|  || . |. ||.| .||..|  
THSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase Cad96Ca.AA VEGFR 582-741 46 4e-80 272.49 In-house 170-332 (332) Show / Hide 
Range on Protein: 582-741
Range on HMM: 170-332/332
Sequence Identity: 46% (75 aa)

LTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARD-VITSKIYERKSE-GKLPIRWMATESLYDNIFSVKSDIWSFGILMWE
||. || .. .|||.||..|.|| .|||||||||||.. . . |  ||| ||.   .   | || . |.|||.||| ||. |.... .||.||.|...||
LTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWE

IVTLGSTPYPGIS-AADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQML
| .||  ||||..   .  .. .||||...|. |  |.| ||  ||. .| |||.|.|    |
IFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase Cad96Ca.AA PDGFR 579-741 46 3e-72 231.18 In-house 195-358 (358) Show / Hide 
Range on Protein: 579-741
Range on HMM: 195-358/358
Sequence Identity: 46% (77 aa)

SNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMW
|||||  || .| |||||||..| |   .||||||||.|..  .  |. ||| |||.     |  |    ||. ||| ||..|... ..||.||.||| |
SNVLTYWDLLCFSYQVAKGMEFLASKNCVHRDLAARNVLLCHGKVVKICDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFDCVYTTQSDVWSYGILLW

EIVTLGSTPYPGISAADVM-RKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQML
|| .||..||||.   .   .....||| ..|.|   | | ||  ||  ||. || | .. |.|
EIFSLGGNPYPGMPVDSKFYKMIKEGYRMAQPFHAPEEIYEIMQKCWDFDPEKRPTFQQLCQFL
Kinase Cad96Ca.AA Pkinase 470-741 23 1.9e-48 172.06 Pfam 1-293 (293) Show / Hide 
Range on Protein: 470-741
Range on HMM: 1-293/293
Sequence Identity: 23% (73 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEV--DRKDLL-SELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRG----KLQTY
...  ..|.|.||.|  ....... ..   .||||..| . ..   |. ... ||...||.|  | |.| |.....|||   ...||.. |     | .|
YHIGRKIGSGSFGCV--YKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

LRSSRAERHYGNTHGKSNVL--TSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTC----KVADFGFARDVITSKIYERKSEGKLPIRWMAT
..             .....  .  .. ..|||...|..|. |.|||||||   |||| .. ..    |..|||.|. .     ..  .     ...|| 
IST-----------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAP

ESLY-DNIFSVKSDIWSFGILMWEIVTLGSTPYPGI----SAADVMRKVRDGYRLEKPEHCR-----------------------RELYNIMYYCWSHDP
| .  ..  . |.|.||.|....| .. | .|.||     . .| | ...   . . ....                        .|.  ....|.  ||
EVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP

QERPLFAEIIQM--L
..|| ...| |   .
KKRPTAEQILQHPWF
Kinase Cad96Ca.AA S_TKc 470-745 23 1.3e-46 162.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 470-745
Range on HMM: 1-231/231
Sequence Identity: 23% (67 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNR--GKLQTYLRSSR
 .. ...|.||||.|..|  ..         ||.| .|        .....|....|.   | |.|.|.... | |  ....||..   | | .|... .
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

AERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKLPIRWMATESLYDNIFSV-
 .. .        ...  .  ..|||......|. |.|||||||   |||...  . |..|||.|| .         .       .|| | |    ..  
RHGLR-------FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKC

KSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQ-----MLDKLL
|.|.||.|....| .. | .|.|    . ...|..            .|. ...  |.  ||..||   |. |     ...  .
KCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Cad96Ca.AA VEGFR 470-567 48 1e-34 121.64 In-house 1-101 (332) Show / Hide 
Range on Protein: 470-567
Range on HMM: 1-101/332
Sequence Identity: 48% (49 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCT---DKDPTFVILEYVNRGKLQTYLRSS
||    ||.||||||   .| .|.. |. |||||| ||| ||    . |.|||.... .  | ||| .|||||    | | .|| ||.. | |..|||. 
LKLGKMLGRGAFGQVHEASAFGIRKMETCTTVAVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTK

R
|
R
Kinase Cad96Ca.AA PDGFR 470-567 40 6.2e-23 70.13 In-house 1-98 (358) Show / Hide 
Range on Protein: 470-567
Range on HMM: 1-98/358
Sequence Identity: 40% (40 aa)

LKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSR
|.|  .|| ||||.|    |  .   .   .|||| ||..|    .  | ||| .|  | .| |.| ||| ||   |...| ||   | |  ||.. |
LQFGKTLGSGAFGKVVEATAYGLSKSQAVMKVAVKMLKPTAHSSEKEALMSELKIMSHLGQHMNIVNLLGACTHGGPIYIITEYCCYGDLLNYLHRKR