Gene TOR (Fruit Fly)

TOR

Species: Fruit Fly
Alias: l(2)k17004, CT24745, splc, dTOR, CG1389, TOR, CG5092, splc: spliced, spliced, CT16317, CT24817, SFO006, Target of rapamycin, FRAP/TOR, Tor
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 43E13,

Classification

Group: Atypical
Family: PIKK
Subfamily: FRAP

Sequence

Name Sequence Type Origin Length Description Download
Tor.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 12 Kinase domain by global Sugen HMM Fasta, JSON
Tor.AA Protein Various 2470 None Fasta, JSON

Protein domain

Protein domains of Tor.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HEAT Tor.AA HEAT 177-207 19 0.097361 9.88 Pfam 1-31 (31) Show / Hide 
Range on Protein: 177-207
Range on HMM: 1-31/31
Sequence Identity: 19% (6 aa)

FFEVIFNAIFDPKPAIRESAGEALRAALIVT
......... || . .||.| ..| . . . 
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT Tor.AA HEAT 358-388 19 5.295697 3.87 Pfam 1-31 (31) Show / Hide 
Range on Protein: 358-388
Range on HMM: 1-31/31
Sequence Identity: 19% (6 aa)

ICDNVLEQRTSKSPYVQQALLQILPRLAAFN
|.. .|.  ..... |..| .. | .|. . 
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT Tor.AA HEAT 591-611 19 14.642062 2.34 Pfam 11-31 (31) Show / Hide 
Range on Protein: 591-611
Range on HMM: 11-31/31
Sequence Identity: 19% (4 aa)

HEQQEIRLEAVQTCTRLLKLA
..  |.|. |... ..|.. .
DPDWEVREAACWCLGQLCEHC
HEAT Tor.AA HEAT 669-698 33 12.734768 2.55 Pfam 2-31 (31) Show / Hide 
Range on Protein: 669-698
Range on HMM: 2-31/31
Sequence Identity: 33% (10 aa)

LNSLFITLHDEIFEIRELAMVTIGRLSSIN
|. |.  |.|.  |.|| |  ..|.|... 
LPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT Tor.AA HEAT 751-783 27 44.395513 0.67 Pfam 1-31 (31) Show / Hide 
Range on Protein: 751-783
Range on HMM: 1-31/31
Sequence Identity: 27% (9 aa)

ILKALVPKLHEPESNPGVILNVLRTIGDLAEVN
|| .|.  |. |  .. | .......|.|.|. 
ILPHLLKCLNDP--DWEVREAACWCLGQLCEHC
HEAT Tor.AA HEAT 796-827 37 0.000496 17.82 Pfam 1-31 (31) Show / Hide 
Range on Protein: 796-827
Range on HMM: 1-31/31
Sequence Identity: 37% (12 aa)

LLSILLEMLGDAGSPDKRGVALWTLGQLISAT
.|..||..| |  ... |  |.|.||||..  
ILPHLLKCLNDP-DWEVREAACWCLGQLCEHC
DUF3385 Tor.AA DUF3385 830-998 45 4.4e-85 293.78 Pfam 1-181 (181) Show / Hide 
Range on Protein: 830-998
Range on HMM: 1-181/181
Sequence Identity: 45% (84 aa)

VVTPYHKYPVLIDILINFLKTE-QRRSIRRETIRVLGLLGAMDPYKHKMNKGLIDSQKDNVLIAYSDGKV-DESQDISTAELLVNMGN---ALDEYYPAV
|..||..|| | ..|.|.|||| |. .||||||...| |||.||||||||  .|. . |...|.. ....  .. ...| ..|...|.   ..|||||.|
VIDPYYDYPQLLGVLFNILKTEFQNWPIRRETIKCMGILGALDPYKHKMN--EIERHSDKHHIKF-RDDQHQNQNNPCTDIMLMMQGYSPLSNDEYYPTV

AIAALMR-ILRDPTLSTRHT-SVVQAV----TFIF--QSLGIKC-VPYLAQVLPNLLDNVRTADN-NLREFLFQQLAILVAFVK
.| .||| ||.||.||. || .||||.    ..||  ...|.|| ||.|.|..| .| ..||... .||||.||||..|| .||
VINSLMRLILKDPSLSSHHTVMVVQAITWWEMYIFSLKTMGLKCQVPFLPQIIPPFLQVMRTCPPCSLREFYFQQLCTLVSIVK
TPR_1 Tor.AA TPR_1 907-917 45 72.268329 0.03 Pfam 1-11 (34) Show / Hide 
Range on Protein: 907-917
Range on HMM: 1-11/34
Sequence Identity: 45% (5 aa)

AELLVNMGNAL
|| . |.||..
AEAWYNLGNCY
HEAT Tor.AA HEAT 1048-1078 19 6.817667 3.49 Pfam 1-31 (31) Show / Hide 
Range on Protein: 1048-1078
Range on HMM: 1-31/31
Sequence Identity: 19% (6 aa)

LIPQILRVLQHDNSKDRMVTRRLLQALQKFG
..| .|. |...... |. . . | .| .. 
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT Tor.AA HEAT 1088-1099 41 46.816404 0.59 Pfam 1-12 (31) Show / Hide 
Range on Protein: 1088-1099
Range on HMM: 1-12/31
Sequence Identity: 41% (5 aa)

ILPPIVKLFDSP
|||...|....|
ILPHLLKCLNDP
HEAT Tor.AA HEAT 1138-1158 28 1.162936 6.15 Pfam 11-31 (31) Show / Hide 
Range on Protein: 1138-1158
Range on HMM: 11-31/31
Sequence Identity: 28% (6 aa)

DAEPELRDQAMTTLRSLAKQL
| ..| |..|  .| .|....
DPDWEVREAACWCLGQLCEHC
TPR_2 Tor.AA TPR_2 1407-1440 38 0.000188 19.84 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1407-1440
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

ANELNVQGRWYEKLHNWDEALEHYERNLKTDSSD
|  .. .|. |.|. ..|||.|.||. || |  .
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 Tor.AA TPR_1 1407-1440 32 0.000616 17.73 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1407-1440
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

ANELNVQGRWYEKLHNWDEALEHYERNLKTDSSD
|. ..  |  |.|. |.|||.|.|.. |. . ..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR Tor.AA TPR 1407-1440 32 0.001748 18.82 SMART 1-34 (34) Show / Hide 
Range on Protein: 1407-1440
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

ANELNVQGRWYEKLHNWDEALEHYERNLKTDSSD
|  .. .|  |.|. ..|||.|.|.. |. | ..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
FAT Tor.AA FAT 1480-1829 36 2.4e-158 530.41 Pfam 1-408 (408) Show / Hide 
Range on Protein: 1480-1829
Range on HMM: 1-408/408
Sequence Identity: 36% (155 aa)

GPLAAVAAWGLQDWEA--MREYVRCIP------------EDTQ-----DGSYYRAVLAV--HHDDFE--TAQRLIDETRDLLDTELTS-MAGESYERAYG
 |||| |||.|..|.   |.||.....            ||..     |.|...|.|..  ||..|.   |.|.||..|.|||||.|. ..||||.|.|.
APLAAEAAWRLGQWDETYMDEYISVMKKLLGEDQLTFIDEDSPDEPTWDRSFFQAILCLYKHHNQFDTYEAHRYIDKARQLLDTEWTACLPGESYNRHYP

AMVCVQMLAELEEVIQYK-LI-----------PERREPLKTMWWKRLQGG-QRLVEDWRRIIQVHSLVVK--------------PHEDIHTWLKYASLCR
.||.|||||||||.||||              ||... .. .|||||.|  || ||.| ||......|..              ||||...|.|.|.|||
VMVRVQMLAELEEIIQYKSQCNQNNAQNLDNSPEKQKHMRQTWWKRLPGCKQRNVEVWQRILTWRQHVFSKINQRYMNSFCYRGPHEDMWMWIKFANLCR

KSGSLHLSHKTLVMLLGTDPKLNPNQPLPCNQPQVTYAYTKYMAANNQLQEAYEQLTHFVS-TYSQELSCLPPEAL---------------KQQDQRLMA
|.| . |..|||.||...||....  |  . .||.|||| ||| | .| |||...|  |.| .....| . . . .               ... ..|.|
KHGRMQLCEKTLKMLYTYDPSEEDWHP--RAPPQWTYAYLKYMWATGQQQEAFQHLREFTSCHMQHDLGVHNNNEINGLTYNLEVINNTNLEYFYTKLLA

-RCYLRMATWQNKL-----QDSIRPDAIQGALECFEKATSYDPNWYK-AWHLWAYMNFKVVQAQKSALDKQQPPGASMGMTMGSGLDSDLM--IIQRYAV
 |||.. . ||.||     ..  ... ....|.|. .|| .||.||| ||| ||..||.|.|..... ......                .  .|....|
MRCYHKQGMWQWKLYEEQYMN-WNQEQKDEILQCYMTATHFDPQWYKKAWHNWALYNFEVFQHYQCQPQREEQN----------------YTHMIIQHVV

PAVQGFFRSISLIKG-NSLQDTLRLLT
|||..||.||.| .| ||.|||||||.
PAVKCFFHSIALSQGSNSRQDTLRLLW
TPR_2 Tor.AA TPR_2 1735-1751 47 0.142549 9.65 Pfam 18-34 (34) Show / Hide 
Range on Protein: 1735-1751
Range on HMM: 18-34/34
Sequence Identity: 47% (8 aa)

QGALECFEKATSYDPNW
. |.|..||| ..|||.
DEAIEYYEKALKLDPNN
TPR Tor.AA TPR 1712-1751 27 0.624906 2.38 SMART 1-34 (34) Show / Hide 
Range on Protein: 1712-1751
Range on HMM: 1-34/34
Sequence Identity: 27% (11 aa)

ARCYLRMATWQNKLQDSIRPDAIQGALECFEKATSYDPNW
|.......    |. |      .. |.||..|| . ||| 
AEAWYNLGNCYYKMGD------YDEAIECYQKALELDPNN
TPR_1 Tor.AA TPR_1 1737-1750 50 2.506769 5.13 Pfam 20-33 (34) Show / Hide 
Range on Protein: 1737-1750
Range on HMM: 20-33/34
Sequence Identity: 50% (7 aa)

ALECFEKATSYDPN
|.||..|| . .||
AIECYQKALELNPN
TPR_2 Tor.AA TPR_2 1508-1541 11 70.602509 0.11 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1508-1541
Range on HMM: 1-34/34
Sequence Identity: 11% (4 aa)

QDGSYYRAVLAVHHDDFETAQRLIDETRDLLDTE
 .. |...... .  |.. | .. ..   |  . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
Rapamycin_bind Tor.AA Rapamycin_bind 1936-2035 65 7.2e-73 231.99 Pfam 1-100 (100) Show / Hide 
Range on Protein: 1936-2035
Range on HMM: 1-100/100
Sequence Identity: 65% (65 aa)

ELIRVAILWHEQWHEGLEEASRLYFGDRNVKGMFEILEPLHAMLERGPQTLKETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAWDIYYHVFQKISRQ
|||||||||||.||||||||||.||||.|...||.||||||.|||.||.|..|.|| |..||.|.||.|| |.|| .  . .|..||||||.||..|..|
ELIRVAILWHEMWHEGLEEASRQYFGDHNIEKMFNILEPLHEMLEKGPETMREISFVQQFGRDLQEAHEWCQKYKRTGDENCLNQAWDIYYQVFRRIRKQ
Kinase Tor.AA FRAP 2102-2352 70 4.1e-189 634.54 In-house 1-251 (251) Show / Hide 
Range on Protein: 2102-2352
Range on HMM: 1-251/251
Sequence Identity: 70% (177 aa)

DYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRDKKKVPLNQEHRTMLNFAPDYDHLTL
.|..|||||||.|||||||||| |.|.||  .|.| ..|| ||||..||||.|.||||||.|||||| ||||||.|... .| |.. |.  ..|||||.|
EYHFLLKGHEDIRQDERVMQLFGLINRLLHNNPETQKKNLSIQRYSIIPLSMNTGLIGWVHHCDTLHILIRDYRKKYHIRYNIEYNIMDRMCNDYDHLPL

MQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLT
|.|||.|....  |.|.||.||||||||.||.||||| |||||||.|||.|||||||||||||.||.|..|||.||||||||||||.|||||||||||||
MNKVEIFRYIMNNTKGEDLKKLLWLKSPNSEIWFERRTNYTRSLATMSMAGYILGLGDRHPSNIMLQRYTGKIVHIDFGDCFEVAMRREKFPEKIPFRLT

RMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNWRL
|||. |||..||||.|| ||| || |.| .|.|.||||||||||||..|||
RMLVNAMEACGIEGNYRNTCELVMKVIREHKESVMAVLEAFVYDPLFYWRL
Kinase Tor.AA PIKK 2073-2342 47 6.30000000001e-151 507.7 In-house 1-290 (290) Show / Hide 
Range on Protein: 2073-2342
Range on HMM: 1-290/290
Sequence Identity: 47% (139 aa)

RISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIR
||  .   ..|...||.|.|. |||..|| | ||.|||||||||.||||||.|.||.|  || . .|.| |..|.|||.|...|||.||..|.||.....
RIRFMDRMVTVMAHKQKPKKIYIRGHDGKEYPYLCKGHEDLRQDQRVMQLFQLMNTCLQKDPECQKRHLHIRTYSVIPMSQRCGLIEWVDNCVTLKEIYK

DYRDKKKVPLNQE--------------------HRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVG
....||.   .||                    .. |.  ...|.|..|..|||||....  | .|...|..|.|.|..| |.||| |||||.|||.|||
QWCQKKHIRHEQEAQMNYQTCMYRDWLKQMSYYKHQMQQQCMMYQHWPLHEKVEVFREQMQNTPPDMFKKWFWRKFPDPEIWWERRENYTRSYAVMCMVG

YILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAF
||||||||||.|.|.|. .|.|.|||||.|||.||.|...|||.||||||... ||...|.|| .||.||.|| ..|.....||.|.|.|
YILGLGDRHPENIMIDMQTGEIVHIDFGCCFESAMQRLPVPEKVPFRLTRNMVNAMGPMGVEGVFRRCCEHVMMCMRQHRETLMTVCEVF
Kinase Tor.AA PI3Kc 2104-2424 27 6e-111 375.8 SMART 1-336 (336) Show / Hide 
Range on Protein: 2104-2424
Range on HMM: 1-336/336
Sequence Identity: 27% (98 aa)

MYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRDKKKVPLNQEHRTMLNF-----------
  ..|...|||||.|.||.|.|.|...  |  ..||.| ...|..||.. ..|.|.|||.|.|||.. . |...||.|.. ....|..            
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNMYM

----------APDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSS-ELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGD
          ...|.|.|.|.....||.|........|.. .| ..|.. | |.|.|.|.|||.|...||.||||.||||..|.|||...|...|||||.
MIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPNEDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFGH

CFEVAMTREKFP----EKIPFRLTRMLIKAME----VTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPL-LNWRLL--DVDKKGNDAVAGAGAPG
.|. ......|.    |. |||||.... .|.    ..| .| .|..|.......|......|...|..||||.  .||    |... ..     .    
IFGHGPKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWRMMEKDIKYLRQRFRLDH----

GRGGSGMQDSLSNSVEDSLPMAKSKPYDPTLQQGGLHNNVADETNSKASQVIKR
             |.|....... .  ..|.  . ...    ...  .  . . 
------------LSDEEAAQYFMQT--MCTKLIEHSNESWTTRMYWMFHNWAQY
Kinase Tor.AA PI3_PI4_kinase 2102-2352 35 2.7e-108 370.85 Pfam 1-300 (300) Show / Hide 
Range on Protein: 2102-2352
Range on HMM: 1-300/300
Sequence Identity: 35% (105 aa)

DYMYLLKGHEDLR--QDERVMQLF-----------------------SLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRD
.| ...||..|||  ||.|.||..                       .|.|...  |  ..|||. .| | .||.....|.|.|||.|.|.|...| |. 
WYPFIFKGGDDLRCRQDMRMMQMICVFKPKDEEPYANNPNKWTMWQHRLMNKCWKKDGCDRRRNMQMQPYRCIPTGPWCGMIEWVPNCTTFHEIPRTYMV

KKK-VPLNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSS-ELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLML--DRMSG
|.|  ..|.||. ..  .||..||..||||||||... .|....| ...| ..|.  | |.|.|.|..||.|.|..|.||||.||||..|.|.  |. .|
KCKHKHFNKEHKMWMKMWPDWWHLMRMQKVEVFEMRIMKTPKPGLYQWFWKHNPDAYEEWWEARDNFVRSCAGMCVVDYILGNGDRHNDNIMVKDDKTTG

KILHIDFGDCFE-VAMTREKFPEKIPFRLTR------MLIKAM------EVTGIEGTYRRTCESVMLVLRRNKDSLMAVL-------EAFVYDPLLNWRL
.. |||||.||. ..| ....||..|||.|.      ....||      ...| .|..|..|......|||.....|..|       |..|.|.|..|| 
HLFHIDFGHCFPHWKMKHFHKPERVPFRWTHWPQAKKPMVHAMGGYISLDPSGDYGWFRDYCWHAYRALRRHMNLCMNLLKKAVMRGECMVHDGLPMWRS
Kinase Tor.AA ATR 2073-2342 32 3.1e-58 196.89 In-house 2-267 (267) Show / Hide 
Range on Protein: 2073-2342
Range on HMM: 2-267/267
Sequence Identity: 32% (87 aa)

RISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIR
 |. .   .....| |.|.|. ..||.|| |. . | ..|||.| | |.  .|.| ... | .  || . .. ||||||  ....| ||    ||.... 
YIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCREMRFNELINFCNRKDYEERRRFYHMRTYAVIPLNDQCCIIEWVNNTATLRPILD

DYRDKKKVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSG
     ||.   .     |    |     . .|  ||   |              . | .. |.  |.|| || ||..|||||.||||||  |...|.. |
KLWKEKKQ---YMQFYQLRQCMDKKSREEWEKQKVFREFLLPRHPPIFHDWFNRRFPDPQQWYSSRENYCRSYAVWCMVGYIIGLGDRHTDNILIDKING

KILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAF
 . |.|.   |    . |  || .|||||. .. .|   . .| .|| || .| ..| ..| .|.|...|
ECVHVDYNCIFNSGEQFE-VPEIVPFRLTHNMVFGMGPMKTYGLFRRACEVIMMCMRDHRDDIMSVWDCF
Kinase Tor.AA ATM 2233-2350 47 1.9e-41 129.95 In-house 132-248 (304) Show / Hide 
Range on Protein: 2233-2350
Range on HMM: 132-248/304
Sequence Identity: 47% (56 aa)

LWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNK
.|||.|  |||| |  |.|||||||||||  |...   |  . ||| |  ||        || .|||||| ..  | .||.|| .|| ||  | |.|  .
IWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPT-PETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQ

DSLMAVLEAFVYDPLLNW
. |. . |  .||||  |
ETLLTIVEVLLYDPLFDW
Kinase Tor.AA SMG1 2081-2161 45 8.8e-21 65.44 In-house 1-81 (242) Show / Hide 
Range on Protein: 2081-2161
Range on HMM: 1-81/242
Sequence Identity: 45% (38 aa)

LQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLL--LDDPDTFRRNLAIQRYAVIPLSTNSGLIGWV
. ..  | .|.||   || || | || || |||  |||.||  |.|||.   ..  .| |       |.| || | |||| ||
ITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPR--FHARHYSVTPLGTRSGLIQWV
Kinase Tor.AA DNAPK 2238-2352 34 4.5e-19 65.9 In-house 187-301 (301) Show / Hide 
Range on Protein: 2238-2352
Range on HMM: 187-301/301
Sequence Identity: 34% (40 aa)

RNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMA
|  . |. ||    ..||| ||||  | |     | |  ||||  |  |      ||  ||||||  |  |   .| | ..    . |  .|. .  |. 
REHFIRNYAVICISHWILGIGDRHLNNFMVNMENGDIISIDFGHSFGSATQFLPVPELMPFRLTRCFINLMSPMKINGIMYQIMIHSMMAFRKDRNILTN

VLEAFVYDPLLNWRL
  . |. ||.. |  
FCDVFINDPSFDWKN
Kinase Tor.AA DNAPK 2072-2161 37 1.3e-18 64.22 In-house 2-91 (301) Show / Hide 
Range on Protein: 2072-2161
Range on HMM: 2-91/301
Sequence Identity: 37% (34 aa)

IRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWV
.||        |. |  ||... |||   ..  .. || |||||| |. |||   |  .  ||    | |    | .||.    ||| ||
VRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFCYKGIEDLRQDQRIEQLFQVMNNIFEYDPQCQQRELQLRTYNIIPMTNRLGLIEWV
Kinase Tor.AA SMG1 2220-2284 50 2e-18 57.54 In-house 169-233 (242) Show / Hide 
Range on Protein: 2220-2284
Range on HMM: 169-233/242
Sequence Identity: 50% (33 aa)

LAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFE
||| ||      . |.     | || |||||||||.||||||  | ..|   | . |||.  |||
LAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYPICFE
Kinase Tor.AA ATM 2105-2160 46 7.7e-15 43.46 In-house 2-57 (304) Show / Hide 
Range on Protein: 2105-2160
Range on HMM: 2-57/304
Sequence Identity: 46% (26 aa)

YLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGW
 | || .|||||  . | | . ||||    .| .| | |  | |.|||  || . |
QLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEW
Rapamycin_bind Tor.AA Rapamycin_bind 2070-2076 71 4.522223 1.81 Pfam 1-7 (100) Show / Hide 
Range on Protein: 2070-2076
Range on HMM: 1-7/100
Sequence Identity: 71% (5 aa)

ELIRISI
||||..|
ELIRVAI
FATC Tor.AA FATC 2438-2470 57 2.2e-19 65.12 Pfam 1-33 (33) Show / Hide 
Range on Protein: 2438-2470
Range on HMM: 1-33/33
Sequence Identity: 57% (19 aa)

KSVNEQSQVELLIQQATNNENLCQCYIGWCPFW
.. . . ||. |||.||..|||||.||||||.|
EPLSVEQQVDRLIQEATDPENLCQMYIGWCPWW