Gene Taf250 (Fruit Fly)

Taf250

Species: Fruit Fly
Alias: CG17603, TAF[[II]]250/230, Taf[[II]]250, Taf230, l(3)84Ab, TAF200, TBP-associated factor 250, dTAF230, TFIID 230 kda subunit, dTAFII250, cell lethal, dTAF[[II]]250, TFIID TAF250, cell, EfW1, dTAF[[II]]230, TAF250, TAF[[II]]230, SR3-5, Suppressor of Ras85D 3-5, cel, TAF[[II]]250, TAF230, TAFII-250, BG:DS00004.13, p230, d230, TAF250/230, dTAF250, Taf200, TATA-associated factor 250, SFO306, Taf250, TFIID, TAFII250
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 84A1

Classification

Group: Atypical
Family: TAF1

Sequence

Name Sequence Type Origin Length Description Download
Taf250.AA Protein Various 2065 None Fasta, JSON
Taf250.kin_dom Protein Kinase Domain None 8 None Fasta, JSON

Protein domain

Protein domains of Taf250.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TBP-binding Taf250.AA TBP-binding 8-77 43 1.4e-31 110.15 Pfam 1-77 (77) Show / Hide 
Range on Protein: 8-77
Range on HMM: 1-77/77
Sequence Identity: 43% (35 aa)

SDDEGSIGN---GLDLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEV--------IDLKEA
|||......   |..|||.||||||..|.|..||..|    .|.|.|..|...||||.||.|||.||        .| ..|
SDDDNDNERNSRGFNLTGFLFGNIDEHGQLEDDDFRE----QGLDEECKEHLSSLSKMGLGSMLHEVNLLAKSERTDSDDA
DUF3591 Taf250.AA DUF3591 609-1072 38 1.3e-246 830.35 Pfam 1-494 (494) Show / Hide 
Range on Protein: 609-1072
Range on HMM: 1-494/494
Sequence Identity: 38% (192 aa)

FNI--SNDTYYTPKTE-PTLRLK--VGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGPMAQSIPHPV--FPLLKTIAKKAKQREVERIA
|||  |||.||....|  . . .   |.. |.||.| ..|. |. .........|.||||....|.     .   . .  |  || . .|...||.||..
FNIIFSNDEYYDMLKENHQNKVRQTIGNLNIEHSMPALRLQWPYYKVKLNKREARSFHRPHFQFYI-----RPGTQIWVRFSKLKHRKRKHDKREKERMG

SGGGDVFFMRNPEDLSGRD-GDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFV-YGEVAFAHT---SPF--LGILHPGQCIQAIENNMYR
.....||.||...||...| ....|.|.|||.||.....||.|||.|||..| ..|......  .|| .. |.   |||  .| .|||.......|||||
KDISEVFKMRTTKDLTLGDNSPVILMEYCEEYPPVMSNFGMGSKIINYYRKKHMEDTHRPKLDDIGETHVLHPQDKSPFWNFGHVHPGEIVPTLYNNMYR

APIYPHKMAHNDFLVIRTRN------NYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAF-PAHSESSI
|||. ||....|||.||...      .|..| .. ...||| .|..|||||.|....|.....|....|||||.... ..||...||...| | ..|...
APIFKHKPEPTDFLCIRSTTPGGHGQKYYLRNIDHMFCVGQTFPVMEVPGPHSRKVTNMSKNRLKMIVYRLFWGQKSPRHRISIHDITKHFFPDQNEMQN

RKRLKQCADFKRTG-MD-SNWWVIKPEFRLPSE-EEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAP-----QEDDDEEA---QLKLDDEVKVAP
|.|||......|.| || ..||..|....||.| ||||.|..||.||.|.||....|.|.||||...  |..     |||||||.   |.|.|.|...||
RQRLKEFMKYQRDGGMDNQGWWKLKEGETLPDEFEEIRKMITPEDCCLYESMQVGQQHLEDAGYNNTDEFKRDYQQIQEDDDEETKKVQMKIDLEQMMAP

WNTTRAYIQAMRGKCLLQLSGPADPTGCGEGFSYVRV-PNKPT--QTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDV
|||||..|.|..||..|||.|..||||||||||..|. ..|..  ...|... .||..|.||.|..|...........| ..||||||.....|.....
WNTTRNFINATQGKAMLQLHGEGDPTGCGEGFSFIRTKSMKGGFLKQGEGPQDKPKKAVAGTRAKERGGHSYNVAQQQRLYGVPEEEIRRIWYWQKRSL
BROMO Taf250.AA BROMO 1468-1576 24 2.9e-38 134.34 SMART 1-118 (118) Show / Hide 
Range on Protein: 1468-1576
Range on HMM: 1-118/118
Sequence Identity: 24% (29 aa)

RTDPVVVLSSILEIIHNELRSM--------PDVSPFLFPVSAKK--VPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYT
. .   .....|. .......         |. .||. ||..|.  .|||| ....||||.|... .....|.|.|.|..|......|  .||.| | . 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

LAAQRMFSSCFELLAERED
 .|... . . |...| ..
KMAKKLQKFFEEKWREFPP
Bromodomain Taf250.AA Bromodomain 1478-1562 28 3.6e-23 77.86 Pfam 1-89 (89) Show / Hide 
Range on Protein: 1478-1562
Range on HMM: 1-89/89
Sequence Identity: 28% (25 aa)

ILEII-HNELRSMPDVSPFLFPV--SAKKVPDYYRVVTKPMDLQTMREYIRQRRYT-SREMFLEDLKQIVDNSLIYNGPQSAYTLAAQR
...|. .... ..|.  ||. ||  . ...||||.....||||.|... .. . |. . . |..|....  |...|||| | .  .|..
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK
BROMO Taf250.AA BROMO 1590-1698 31 6.5e-42 146.48 SMART 1-118 (118) Show / Hide 
Range on Protein: 1590-1698
Range on HMM: 1-118/118
Sequence Identity: 31% (38 aa)

DDDDQVALSFIFDKLHSQIKQL--------PESWPFLKPVNKKQ--VKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYT
| . |  ..............         | .|||..||..|.  . ||| .||.||||.|| |..| |.|.|. | ..|..|. .|| .||. |. . 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

KFSKKILEYAQTQLIEFSE
|..||. .. . .. || .
KMAKKLQKFFEEKWREFPP
Bromodomain Taf250.AA Bromodomain 1601-1684 35 3.4e-26 87.76 Pfam 1-89 (89) Show / Hide 
Range on Protein: 1601-1684
Range on HMM: 1-89/89
Sequence Identity: 35% (32 aa)

FDKLHS--QIKQLPESWPFLKPV--NKKQVKDYYTVIKRPMDLETIGKNIEAHRYH-SRAEYLADIELIATNCEQYNGSDTRYTKFSKK
.|.. .  .|.. |...||..||  ..... ||| .||.||||.|| .... . |. . || ..|.||...||. |||.|... | ..|
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK