Gene msn (Fruit Fly)

msn

Species: Fruit Fly
Alias: NIK, l(3)6286, l(3)j1E2, Nik, SFO082, CG16973, Mishappen, msn, msm, MESR5, l(3)03349, l(3)06946, 6286
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 62E6--7

Classification

Group: STE
Family: STE20
Subfamily: MSN

Sequence

Name Sequence Type Origin Length Description Download
msn.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 265 Kinase domain by global Sugen HMM Fasta, JSON
msn.AA Protein Various 1102 None Fasta, JSON

Protein domain

Protein domains of msn.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase msn.AA MSN 32-296 86 2e-207 691.32 In-house 1-265 (265) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-265/265
Sequence Identity: 86% (230 aa)

FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQS
|||.||||||||||||||||.|||||||||||||.||||||||.|||.|||||.||||||||||||||||||.|.|||.|||.|||||||||||.|||||
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKGQS

LKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITAL
|||.|||||||||||||..||..|||||||||||||||.||||||||||||||||||.|||||||||||||||||||||||||||||.||||||.||||.
LKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGITAI

EMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFI
||||.||||||.||||||||||||.||.||||||||||| |....|.|.||||||||..|||.||
EMAEGQPPLCDMHPMRALFLIPRNPPPKLKSKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase msn.AA STE20 32-296 52 1.2e-167 563.3 In-house 1-288 (288) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-288/288
Sequence Identity: 52% (153 aa)

FELIEVVGNGTYGQVYKGRHTKTGQL----AAIKVMDVTE-----DEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTD
.||.|..|.|.||.|||..|..||..    .|||.|.. .     ||.|.|. ||...|..  | || .|||...|....  ||.||.||||||.||.||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTC--DDELWIVMEYCGGGSLTD

LVKS--TKGQ-----SLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDR----TIG-RRNTFIGTPYWMAPEVIACD
..|   ..|.     ...||.|||||||.|.||.|||||..||||||..|.|||...||||.||||.|||..    |.. .||||.|||||||||||.|.
IMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCM

ENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIP--RNSPPRLK---SKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFI
|.||  ||...| |||||||.|||| .||..|.|||||.|.||  .| ||.||   ..|||..|| |.|. |.||...|| .. |||| ||
EGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase msn.AA STE 32-296 36 3.8e-137 461.93 In-house 1-359 (359) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-359/359
Sequence Identity: 36% (134 aa)

FELIEVVGNGTYGQVYKGRHTK---------------TGQLAAIKVMDVTE------------------DEEEEIKLEINVLKKYSN-HRNIATYYGAFI
.|.||..|.|..|.|||... |               ||.. |||.|.. .                  .|...|. ||...||... | || .|||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KKSPP-GKDDQLWLVMEYCGAGSVTDLVKS--TKGQSLK----------EEWIAYICREILRG-LSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSA
|.... . ||.||..|||...||..|..|.   .|..|.          |..||||||.||.| |.||||...||||||..|.||     |||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLDR---------------TIG-RRNTFIGTPYWMAPEVIACDENP-DATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRN-----------
||.                |.. .||||.||| ||||||| ..... |  || ..| ||||.|..|||. .||..|.|||||.|.||.|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----SPPRLKS------------------KKWSKKFHGFIDTVLVKDYHQRPYTENLLK--HGFI
     ||.|..                  .|||..|. ||.  |.||...|| .. |||  | ||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase msn.AA NinaC 32-296 52 2e-128 432.97 In-house 1-267 (267) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-267/267
Sequence Identity: 52% (140 aa)

FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKS--TKG
.| .| .| |||| |.|    . ||.||.|...  .| .|||  | |.|..|..| |.  .|| . || . .  ||||.|||||  |||||.||     |
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCN-GDQLWFVMEYCNGGSVTDMVKGLLKCG

QSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGIT
. ..|| |||| .| ..||  ||.|.|||||.|| |.||| .  |||.||||||||| | .|||| .|||.||||||||| .  | .|| | | ||||||
RRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGIT

ALEMAESQPPLCDLHPMRALFLIPRNSPPRLKS-KKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFI
| |..   ||. |.|||||.| |||| ||.|    .|...|  ||   | ||| .||   ..|.| ||
AIELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase msn.AA YSK 32-296 48 4.5e-127 384.78 In-house 1-257 (257) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-257/257
Sequence Identity: 48% (131 aa)

FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEE--EEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKG
|   |..| | .| ||||   .|..  |||. |  ..|.  | |  ||..|       .|  |||..       ||  || .||||| ||. || |.   
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSP-YITKYYGSYL------KDTKLWIIMEYCGGGSCLDLMKPKYV

QSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIAC--DENPDATYDNRSDLWSLG
 .. |. || | |||| ||.||||...||||||  ||||. . .||| ||||..|.  |  .||||.||||||||||| .  ..     ||   | ||||
GQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSY-----YDFKADIWSLG

ITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFI
|||.|||  .||.||.||||..|||| | ||.|. ...|| |  |..  |.||  |||  ..|||| ||
ITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase msn.AA MST 32-296 48 1.2e-111 356.15 In-house 1-254 (254) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-254/254
Sequence Identity: 48% (129 aa)

FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEE-EEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQ
|...|  | | ||.|||  | .||.. |||.. |  .|  .||. ||. ..   .  .| .||| ..      |. ..|.||||||.||| |..| |. .
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV--NEDLQEIIKEISIMQQCKSK-YIVKYYGSYFD----AKNNHCWIVMEYCGMGSVCDIMKITQ-R

SLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITA
 | |. || |..  |.|| |||.|| ||||||  | ||    | || |||||.||  | . |||.||||||||||||         ||.  | |||||||
TLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQ-----EIKYDCKADIWSLGITA

LEMAESQPPLCDLHPMRALFLIPRNSPPRLKS-KKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFI
.||||. ||. |.|||||.|.|| . || .|   .||  |  |.   |.|.  ||.  | ||.| ||
IEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase msn.AA KHS 32-296 49 9.5e-108 363.52 In-house 1-258 (258) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-258/258
Sequence Identity: 49% (133 aa)

FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEE-EEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQ
.||.  || ||||.||| |......|||.||. .  ... . |. || ..|. . | ||  |.|.....      |.||..|||||.||. |. . |   
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCR-HPNIVAYFGSYLRR------DKLWICMEYCGGGSLQDIYHVT--G

SLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITA
.|.|  |||.|||.|.|| ||||.. .|||||| |.||||. .||| |||||||.  ||..|  |||||||||||| | . .    |..  |.|..||||
PLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERK--GGYNQLCDIWAVGITA

LEMAESQPPLCDLHPMRALFLIPRNS--PPRLKSK-KWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFI
.|.|| |||. ||||||||||. . .  ||.|| | |||..|| |. . |.|.  .||  | ||.| |.
IELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase msn.AA PAKA 32-296 40 2e-98 333.29 In-house 1-260 (260) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-260/260
Sequence Identity: 40% (110 aa)

FELIEVVGNGTYGQVYKGRHTKTGQL--AAIKVMDVTEDEEE-EIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTK
.. .| .| |  |.||..  .||.|    |||.|.. ..     |. || |.|. ..| ||  |. ...       ||.||.|||| ..|. ||... . 
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKE-CKHKNIVNYIDSYLV------DDELWVVMEYMEGGCLTDVITQCC

--GQS-LKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWS
    . ..|. |||.|||.|.||...||...||||||  |.||  ...||. |||  ||| .   .|||  |||||||||||   .     ||   | ||
NIQCNYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ-----YDEKVDIWS

LGITALEMAESQPPLCDLHPMRALFLIPRN-SPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFI
||| |.||.|..||  .  | ||..||  |  |...   |||..|. | |. | .|  .|. .. ||.| |.
LGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase msn.AA PAKL 32-296 43 9.8e-95 321.03 In-house 1-256 (256) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-256/256
Sequence Identity: 43% (116 aa)

FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTED-EEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQ
||. |  | | || |||. |  |.   ||||. ..|  | ..|  ||..|||  .  ||  |.|    |      ...|  |.|| .||. |. .|. . 
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKK-CKCPNIVSYFGSIQQKL-----NHYWILMDYCSLGSINDMMESC-CK

SLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIG-RRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGIT
.|.|. |. | .  |.|| ||||  .||||||  |.||.  . ||. ||||| ||. . .   |  ||||||||||.|       . |.|  | ||||||
TLNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINK-----QNYNNKCDIWSLGIT

ALEMAESQPPLCDLHPMRALFLIPRNSPPRLKS-KKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFI
| |||.. ||. |. ||||.  ||.  || ..  |.||. |  |... .|||  .|.    || | ||
AIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase msn.AA SLK 32-296 41 1.4e-90 305.78 In-house 1-259 (259) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-259/259
Sequence Identity: 41% (111 aa)

FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEE-EEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQ
.|.|  .|.| .|.||| .|  ....|| |.... ..|| |.   ||..| .   | ||   |.|.        |..||...|.|. | | | .    ..
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECK-HPNIVKLYEAYY------YDNKLWMMIEFCDGGAV-DNIMVELEH

SLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITA
.|.|. |.|.|.... .| .||||||||||.|  |.|.| . .|.| ||||||.. .|. .| |||||||||||||..|.   |. || ..|.|||||| 
PLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITL

LEMAESQPPLCDLHPMRALFLIPRNSPPRLKS-KKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFI
.|||.  ||  .. ||| |. | .  ||.|.   .|||.|. |.   |||| ..|. |..|..| ..
IEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase msn.AA S_TKc 32-296 31 3.6e-89 303.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-231/231
Sequence Identity: 31% (87 aa)

FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGA--GSVTDLVKSTKG
.|.....| |..|.|||.||.|||.. |||...      | |. ||..|||  .| || ..|..|         | |..|||||.   |.. |. |. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGR

----QSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDN-RSDLW
    . . | ........|...| |.||...||||.| .|.||..  ..|. |||...||       .||.|||..|||||.         |.  ..| |
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL--------GYGKCKCDWW

SLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLK-------HGFI
|.|..  ||.  .|| .  .... . .|             |. .  ||.  |.||  .||    .|.       | ..
SCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase msn.AA Pkinase 32-296 27 1.3e-74 258.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-293/293
Sequence Identity: 27% (85 aa)

FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKL-----EINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAG----SVTD
.......| |..|.|||..| .||.. |.|.... ...... .      || ..|.  || || ..|..|        .| ...|||||. |    .  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFD

LVKSTKGQSL--KEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEV----KLVDFGVSAQL-DRTIGRRNTFIGTPYWMAPEVIACDENPDA
...  .. ..   |. .  ....||||| |.||...||||.| .|.|. .| ..    |. |||...|.     .  .|| |||..||||||      . 
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GGQ

TYDNRSDLWSLGITALEMAESQPPLCDL----HPMRALFLIPRNSPPRLKSKKW----------------------SKKFHGFIDTVLVKDYHQRPYTEN
 |. ..| ||.|..  ||.  .|| ..     . .. ...| |. .|.|..  .                      |. .  ||.  | || ..||  | 
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ

LLKHGFI
.|.| ..
ILQHPWF
Kinase msn.AA Pkinase_Tyr 32-182 29 3.6e-34 116.37 Pfam 1-158 (270) Show / Hide 
Range on Protein: 32-182
Range on HMM: 1-158/270
Sequence Identity: 29% (47 aa)

FELIEVVGNGTYGQVYKGRHT----KTGQLAAIKVM--DVTEDE--EEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDL
 ..... | | .|.||||. .    .|..  |.|..  . ....   |.   |....|.. .| ||  .||. .... |.   |...||||.  |.  | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDY

VKST--KGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVS
 ..    .|.|. ...  .|..| .|..||.|.. ||||.   |.|.|.|  ||  ||| .
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase msn.AA TyrKc 32-296 22 1.7e-16 44.14 SMART 1-280 (280) Show / Hide 
Range on Protein: 32-296
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKY-SNHRNIATYYGAFIKK-----SPPGKDDQLWLVMEYCGAGSVTDLVK
 .|... |.| .|.||||. .   .  |.|..      .|..  |.....|.  .| ||   ||. ...     .    ...|..||||.  |.  |  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMY----IEPLMIVMEYMPHGDLKDYLR

STKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRT--------IGRRNTFIGTP-----YWMAPEVIACDEN
..... |. .   ..|  | .| .||||...||||.   |.|...|  ||  ||| |  ..            |  .  |.       |||||.|     
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----

PDATYDNRSDLWSLGITALEMAES-QPPLCD-----LHPMRALFLIPRNSPPRLKSK-------KWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFI
 . ..   || || |..  |.    |.|  .     . . ... .. .   ..             ... .  . .    | ..||  ...  | ..
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase msn.AA Pkinase_Tyr 201-229 37 2.579324 1.69 Pfam 180-203 (270) Show / Hide 
Range on Protein: 201-229
Range on HMM: 180-203/270
Sequence Identity: 37% (11 aa)

WMAPEVIACDENPDATYDNRSDLWSLGIT
|||||.|.  .     .   || || |..
WMAPECINYGK-----FTTKSDVWSFGVL
CNH msn.AA CNH 781-1082 27 9.80000000001e-117 395.03 SMART 1-375 (375) Show / Hide 
Range on Protein: 781-1082
Range on HMM: 1-375/375
Sequence Identity: 27% (102 aa)

YKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQ------GKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKSK---------ILRTD
........|.|..|||..||.||| |...|....|      |.......||....|.|.|..|.|..||||| ......|.||..|         |.   
CTMKWCHPITCDQLWGKWLLVGTEHGIYCLNINCQQNQDHEGTPEHIHHRRCVTCMWVYEENNCLMMISGKKPHLYSHPLVWLFQKYRTQGMTPHIQDHM

GLSDQVERRNGW-INVGDLQG-AVHFKI-VKYER--IKFLVIALKDSIEIYAWAPKPYHKFMAFKN----------------FGELEHRPLLVDLTIEDQ
. .. |.|.|.| ....|..| ..|... ....|  |.||. |.. |..||.....|.|||| .|.                |.|... |..|.......
CNHHLVPRKNVWTTKIPDTKGNCHHCCVKCNGKRTGIIFLCHAMQHSVQIYNQWYNPMHKFMCWKSSNNILNNEIEMFKHFRFPEIFPVPVFVCFHHDSF

SRLKVIYGSAE------GFHAVDLD-------------SAEVYDIYLPKHTQGAI------IPHCIVALPNSNG---MQLLLCYDNEGVYVNTVG---RV
 |.....|.        |||.|. .             .  ..|..|. ..| ..       ||... ...|.|   ...||||||.||.||. |   | 
ERPWICIGCDKPVGGMYGFHMVQHHQHCHCNSFNMHESTVNMNDHSLWFMNQQTSHQQDTCKPHQVHQVQQSDGGQRDMYLLCYDNFGVFVNCYGSEWRR

SKNIVLQWGEMPTSVAYIGTGQIMGWGNKAIEIRSVESGHL-DGVFMHK---KAQRLKFLCE---RNDKVFFSSAK
..| .|.|..||...||.. ..||......|.||....|.. ....|..   |......||.   |..|.|..| .
WRNPILHWEFMPEYFAYHY-PYIMAFWDNGIQIRHIKTGEWNTQCIMDRQYIKCRKFRLLCTCECRDRKIFYCSQP
CNH msn.AA CNH 790-1073 23 3e-87 300.94 Pfam 1-336 (336) Show / Hide 
Range on Protein: 790-1073
Range on HMM: 1-336/336
Sequence Identity: 23% (81 aa)

LCAALWGVNLLIG-TENGLMLLDR------SGQGKVYQLISRRRFQQMEVLEGQNILVTI--SGKKNRVRVYYLSWLKSKILRT-DGLSDQVERRN----
.|.. ||..||.| |. ||.....      .......|..|| |..|..|.| .|||..|  ..| ....|..|.||..|.. . .  ..  ....    
VCPCTWGQWLLVGTTDEGLYVYNIRNTRDCRHWTRICQKFSR-RVTQIYVIEEFNILIMISGCDKNKHLYVHPLDWLDQKEQQWHQCHNPKHRCTHRIER

-------GWINVGDLQGAVHFK--IVKYERIKFLVIALKD-----SIEIYAWAP--KPYHKF-------MAFKNFGE-LEHR----PLLVDLTIEDQSRL
       .|. ..|. .. .|.   ..|.....|..|.|      .| .| |..  |..||.       ..|. | | ...     .. ..... .|...
IMPRKFAMWQKLPDTKHCHFFCWIRNGYCNGRCLCCAVKRSGLHSTIKCYEWYHPMKKFHKQRSFKGNQEWFRKFRECFYIPLPPMTECFSMHWLPQEKP

KVIYGSAEGFHAVDLD-SAEVYDIYLPKHTQGAII-----------PHCIVALPNSNGMQLLLCYDNEGVYVNTVGR-VSK--NIVLQWGEMPTSVAYIG
|...|.. |||.|.|| ... .... | ..    .           |.|.. .... .  .|||||...||||. |. .|.  . ...| .||.|.|.  
KLCVGCQKGFHIVNLDGTGQPWWLHDPADHSV--QQDFMARRENCKPICMHRINDD-E-EFLLCYDECCVYVNKQGWPRSRKHDWEIMWEGMPQSFAC-C

TGQIMGWGNKAIEIRSVESG-HLDGVFMHKKAQRLKFLCERN
.......  ..||||.||.| ..|.....  .|...||....
YPYLLAFHPNFIEIRHVETGSEWDACVQCIPGQNIRFLHSGS