Gene SRPK (Fruit Fly)
SRPK
Sequence
Protein domains of SRPK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | SRPK.AA | SRPK | 170-763 | 43 | 0.0 | 924.27 | In-house | 1-554 (554) | Show / Hide |
Range on Protein: 170-763 Range on HMM: 1-554/554 Sequence Identity: 43% (268 aa) YHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPS---------------------NPRRHKTVQMLDDFKITGVNG ||||||||||||||||||||.| . |||.||||||||. ||| ||||.|..||..||. .|.|.. ||.||.||..|.|| YHVIRKLGWGHFSTVWLCWDMQYDRYVAMKIVKSAPHYTETAVDEIKLLQCVRKHDPNPQWMHFLKEYYEDYKRDCKEFDPNRCHVVQLLDHFKHRGPNG THICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMN-SKMYPSLVSRAPKEY .|.||||||||.||||.|...||.|.|...||.|.||||.||||||..|.|||||||||||||||.. ....| |.| .. |. .... |.|..||.. NHYCMVFEVLGHNLLKWIKHYNYQGMPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPENVLLCVNQDYIKRMAAEWTEWQKMGMQMPSSSMVQTAPQHQ REPPITGKMSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQRDERKAPPEQSEEAQEQ .. .. .||||| |||.|||.|. |. .. ..| . | .| |. ... ..... ||. TQCQQ-QKMSKNKKKKMKKKQKQQQEQQEKNQQQKQQMEDDQNDN---------------------------------EDNNQEDNDNEQDNKNNQNQEN DPLTEGTDKAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNSK |...| .| |||. |. | |.. ... .| . .... || . . . ..| | . . | . . .. . .|| .| |. |. NMENEQEEKENTNKQKKNQKKKEQHKDKKEQECQNVQKQNNDPNFE-SQN-DSQMEQETNSCNNQEHKQEKTMQCQDSTKQQNKQ-DQQKEGQKQSEESE PNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKK-DPALDE--CNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADI .| ... ..| ... .| ... ... .|||||||||||..|||||||||||||.||||||||||.||| CESEDMQEQ----------------------------AGKFLVWWKNPRNADLDHKIKIKIADLGNACWVHHHFTEDIQTRQYRSPEVIIGAGYNTPADI WSTACMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPML ||||||.||||||||||||||||.|.||.||.||||||.| ||....|.|.|. . |....|||.|. ||||.||.|| ||||||...|..|..||.||| WSTACMAFELATGDYLFEPHSGEDYSRDDDHIAHIIELCGKIPWHFALSGKYSREFFNKKGELRHIPKLKPWPLMNVLIEKYEWSHEEAKQFEDFLMPML EFDPNKRATAAECLQHPWL ...|.|||||.|||||||| HYNPEKRATAKECLQHPWL |
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Kinase | SRPK.AA | CMGC | 170-763 | 13 | 1.5e-120 | 398.13 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 170-763 Range on HMM: 1-513/513 Sequence Identity: 13% (104 aa) YHVIRKLGWGHFSTVWLCWD--------------LQAMGYVAIKIVKSAPHFAETAR-------------DEIKILKTVRET---------DPSNPRRHK |..|.|.|.|....|. |.| . .||||..|... . |.|. .|||||| .... ||.|. .. YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN TVQMLDDFKITGVNGT-------------HICMVFEVLGDNLLKLIRKSN--YRG------------------------IPLANVKTITRQVLEGLD--Y |...| |. . .|. |...||| .. .|...|.. . |.| ... ... ...|.|.||. | IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY LHTCCK-IIHTDIKPENVLLCVD-----------EPHVRSLATEATQLYCMNSKMYPSLVSRAPKEYREPPITGKMSKNRKKKLKKKAKKRMELFKQQRD .| .. |||.|.||||.|.. . | CHSHWGNIIHRDLKPENILINHNCELITRMMWKSE----------------------------------------------------------------- YLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQRDERKAPPEQSEEAQEQDPLTEGTDKAKKKKKKKNKNKSNQSKGQQPPQL ---------------------------------------------------------------------------------------------------- ENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDSKISSGSVENTSSATNGPHSNSTLPTP ---------------------------------------------------------------------------------------------------- PPPPQAKHKAKKDPALDECNVHVKIADLGNACWVDRH------------------------FTEDIQTRQYRSLEVIIGAG----------YNTSADIWS . . .| | ..||.| |.|.|.. | .|....|| ||. |...|.. |.|. |.|| --------D-W-NPC--QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWS TACMVFELATG--------DYLFEPHSGE-----SYTRDEDHLAHIIELLGPIPREILLNGT-------YAAKSFTRSCELRNISGLK------------ .|. .|. || ..|| .||.. ..... |.|..|...||... ... .|. . . ..... .... .| VGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWS -------------PWGLMDVLLEKYEWSQK--------------------------------DAASFASFLTPMLEFDPNKRATAAECLQHPWL || . ... |... . . .| ||..||.|| ||...||||.. EFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF |
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Kinase | SRPK.AA | CLK | 170-687 | 15 | 5.2e-69 | 205.8 | In-house | 1-268 (350) | Show / Hide |
Range on Protein: 170-687 Range on HMM: 1-268/350 Sequence Identity: 15% (84 aa) YHVIRKLGWGHFSTVWLCWDLQAMG-YVAIKIVKSAPHFAETARDEIK-ILKTVRET-DPSNPRRHKTVQMLDDFKITGVN-GTHICMVFEVLGDNLLKL | .. .|| | |..| ||| . . |||.||.... . | |. ||. |.|.. |. || | .. . ..|.| |. . . |||.||| .| .. . YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFD----YGHGHICIVFELYGLSIYDF IRKSN------YRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVD-----EPHVRSLATEATQLYCMNSKMYPSLVSRAPKEYREPPITG ... | |.. |.. .. ...| .| . || |..||| |||| ... .. . . .. MKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHD-MKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKIN--------------------------- KMSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQRDERKAPPEQSEEAQEQDPLTEGT ---------------------------------------------------------------------------------------------------- DKAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDS ---------------------------------------------------------------------------------------------------- KISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNV---HVKIADLGNAC---WVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTA | . . ... | |... | |.| . | .. ..||.|| ||| | |... |.|| . ----------------------------------KKSNNCVCHYWHVKNTHICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIG CMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLG-PIP | ||| ||. || |. .||| . ...| ||| CILFELYTGFTLFQTHD------NREHLAMMERIMGMPIP |
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Kinase | SRPK.AA | S_TKc | 170-763 | 12 | 1.9e-52 | 181.5 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 170-763 Range on HMM: 1-231/231 Sequence Identity: 12% (79 aa) YHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGD---NLLKLI |...||.| | |..|..|.. .|||||.| |..| ||.||| .|. . | |. . .|..||.| .. .|...| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK----------HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYI RKSNYRG----IPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVR----SLATEATQLYCMNSKMYPSLVSRAPKEYREPPITGKMSK .| ...| .| .. ...|....|.|.| .||| |.||||.||. |. ||.. KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE---HIKICDFGLARQL--------------------------------- NRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQRDERKAPPEQSEEAQEQDPLTEGTDKAK ---------------------------------------------------------------------------------------------------- KKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDSKISS ---------------------------------------------------------------------------------------------------- GSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNT-SADIWSTACMVFELATG | . |. |.. ||. ||.. ..|.|| |...|...| ------------------------------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG DYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAEC .|. ... .....| .. .|. .|..||.|| || |. YPPFP------------QMQMMFKKIG------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EA LQ-------HPWL || |||. LQDEWDIKCHPWF |
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Kinase | SRPK.AA | DYRK | 170-312 | 35 | 6.4e-39 | 135.63 | In-house | 1-138 (320) | Show / Hide |
Range on Protein: 170-312 Range on HMM: 1-138/320 Sequence Identity: 35% (51 aa) YHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKS | .. .| | |. | ||| . .|||||... . |. .| .|||||. .. || . .. |.|.| |. . | |.||| | || .... YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDD--KYHCVHMYDYFYHRN----HLCIVFELLSMNLYEFLKNN NYRGI-PLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLC . .| .| .|.....|.|..|..||.. .||| |.||||..|. HFQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLK |
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Kinase | SRPK.AA | Pkinase | 170-689 | 13 | 3.1e-31 | 111.52 | Pfam | 1-237 (293) | Show / Hide |
Range on Protein: 170-689 Range on HMM: 1-237/293 Sequence Identity: 13% (71 aa) YHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARD------EIKILKTVRETDPSNPRRHKT-VQMLDDFKITGVNGTHICMVFEVLGD-- ||..||.| | |..|..| . ||.||.| | . . ||.|.| .. |. |...| | ..||.||.| .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLN---------HPNIVRLYDWFED----KDHIYMVMEYCEGGL ---NLLKLIRKSNYRGI--PLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMNSKMYPSLVSRAPKEYREPPITGK | .|. ...... . .| . .|.|.||.|.| ..||| |.||||.|. ...|. . YVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILID-NNGHIDA----------------------------------- MSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQRDERKAPPEQSEEAQEQDPLTEGTD ---------------------------------------------------------------------------------------------------- KAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDSK ---------------------------------------------------------------------------------------------------- ISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGNAC---WVDRHFTEDIQ-TRQYRSLEVII-GAGYNTSADIWSTACM .|||.| | |. . . . .. |. |.. ||| | .| ...|.|| |. ----------------------------------------------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCI VFELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPRE ..|...| .| ... . |... | . .||.... LYEMLCGRPPFP-GHC-WHDN-HDQMQMICRIMGPPLHF |
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Kinase | SRPK.AA | DYRK2 | 170-311 | 35 | 3.2e-31 | 98.52 | In-house | 1-135 (318) | Show / Hide |
Range on Protein: 170-311 Range on HMM: 1-135/318 Sequence Identity: 35% (51 aa) YHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKS | . .| | | | | | .||||.. |...| ||.||. |. |. | . | ||| | . |.|..|| |. || ..|.| YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDN--TMNCVHMLDYFYFRN----HHCITFELLSMNLYEYIKKN NYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLL .. |. |..| ....|..|. || .||| | ||||.|| HFQGFSLQLVRRFAHSILQCLRFLHK-NNIIHCDLKPENILL |
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Kinase | SRPK.AA | DYRK | 603-763 | 27 | 3.5e-27 | 96.64 | In-house | 146-320 (320) | Show / Hide |
Range on Protein: 603-763 Range on HMM: 146-320/320 Sequence Identity: 27% (51 aa) VKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNG--TYAAKS .|..| | .| ...... || | ||. |||.| |... |.|| | . || || || .||.. | || |.|.||..|.... .| ... | IKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLF---PGENE---YDQLACIMEVLGMPPKWMIDKGRCRRKHKF FTR--------------------SCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWL |.. .. .... . .. . ... .| | |.. .|..||.|| |... |||||. FDCFMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF |
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Kinase | SRPK.AA | HIPK | 170-311 | 32 | 7.8e-27 | 81.13 | In-house | 1-134 (329) | Show / Hide |
Range on Protein: 170-311 Range on HMM: 1-134/329 Sequence Identity: 32% (46 aa) YHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKS | |. || | | | || ||||| | | .| . |..||. ... .. . . | ... |. . |.|.|||.| || .. YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADE---YHFVRAYECFH----HKNHTCLVFEMLEQNLYDFQKQN NYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLL .. .|| ...|. ||| | | .|| |.||||..| KFMPLPLKHIRPILQQVLTALMKLKELG-LIHADLKPENIML |
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Kinase | SRPK.AA | DYRK1 | 170-312 | 34 | 6.7e-25 | 84.03 | In-house | 1-138 (321) | Show / Hide |
Range on Protein: 170-312 Range on HMM: 1-138/321 Sequence Identity: 34% (49 aa) YHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKS | .. .| | | | .| | ||||||.| | . |. ||..| . . |. . . . |.. |. |.|.|||.| || |.| YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEM--KYYIVHLKRHFMFR----NHLCLVFELLSYNLYDLLRNT NYRGIPLANVKTITRQVLEGLDYLHTC-CKIIHTDIKPENVLLC ..||. | .. . .|.. | .. | .||| |.||||.||| HFRGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLC |
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Kinase | SRPK.AA | YAK | 170-319 | 31 | 1e-21 | 70.19 | In-house | 1-148 (347) | Show / Hide |
Range on Protein: 170-319 Range on HMM: 1-148/347 Sequence Identity: 31% (48 aa) YHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTV-RETDPSNPR-RHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIR | | || | | | | . .|.|..|. . . |. ||.||. || | . . |.| | | | |.||| | || .. YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFF----VHKNHFCLVFEMLSNNLYEYLK KSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCV-DEPHVR ...| ... | |.|.|. | .||| | ||||..|| . | .. QNKFCGFSFQLIRQWTKQILDGMCVLEN-KQIIHCDLKPENIMLCKPNKPEIK |
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Kinase | SRPK.AA | DyrkP | 602-703 | 36 | 2.7e-16 | 49.51 | In-house | 146-241 (323) | Show / Hide |
Range on Protein: 602-703 Range on HMM: 146-241/323 Sequence Identity: 36% (37 aa) HVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSF .||| | | .|.. | .| | || ||||| | |.|| |.. || || || || .| ..||.| .. | | QVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVLFQNDNIQGL------LARVIGIIGPFPEWMMQEGRLVQNFF TR || TR |
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Kinase | SRPK.AA | DYRK1 | 603-703 | 34 | 9.1e-16 | 51.4 | In-house | 145-239 (321) | Show / Hide |
Range on Protein: 603-703 Range on HMM: 145-239/321 Sequence Identity: 34% (35 aa) VKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFT .|| | | .| ... . || | ||| ||..| |... |.|| |.. |. ||. || || . . | . .|.| || |.... . | | |. IKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLF---SGSN---EVDQMNKIVEVLGMPPKHMIDQAPKAHKYFE R . K |
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Kinase | SRPK.AA | DYRK2 | 603-684 | 37 | 5.7e-15 | 44.8 | In-house | 143-219 (318) | Show / Hide |
Range on Protein: 603-684 Range on HMM: 143-219/318 Sequence Identity: 37% (31 aa) VKIADLGNACWVDR-HFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLG .|..| | | ... .. .||.| ||. |||.| |... |.|| | . || || || || . | .| ..|.|| IKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLF---PGENE---NDQFACMMEVLG |
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Kinase | SRPK.AA | PRP4 | 170-310 | 32 | 4.1e-13 | 44.42 | In-house | 1-138 (320) | Show / Hide |
Range on Protein: 170-310 Range on HMM: 1-138/320 Sequence Identity: 32% (47 aa) YHVIRKLGWGHFSTVWLCWDLQAMG-YVAIKIVKSAPHFAETARDEIKILKTVRET--DPSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLI | |. . | | ||.| | |. |||||. . . | |. ||. .. |. | . | |.| . |. |.|.||| . || .. YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDK-NDKFH-CVRMFRHFNHR----QHMCLVFECMSMNLREVL RK-SNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVL | | | | ..| . | | |.|.| |||| |.| KKYGKDVGLHLKAVRSYAQQLFLALKHLKK-CNILHADIKPDNIL |
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Kinase | SRPK.AA | CLK | 743-763 | 57 | 6.8e-11 | 28.16 | In-house | 330-350 (350) | Show / Hide |
Range on Protein: 743-763 Range on HMM: 330-350/350 Sequence Identity: 57% (12 aa) MLEFDPNKRATAAECLQHPWL |||.||.|| |... ||||. MLEYDPSKRITCKDALQHPFF |
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Kinase | SRPK.AA | Pkinase | 725-763 | 24 | 3.6e-09 | 33.49 | Pfam | 236-293 (293) | Show / Hide |
Range on Protein: 725-763 Range on HMM: 236-293/293 Sequence Identity: 24% (14 aa) KYEWSQKDA-------------------ASFASFLTPMLEFDPNKRATAAECLQHPWL ...|.... .. .|.. .|..||.|| ||...|||||. HFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | SRPK.AA | YAK | 603-654 | 44 | 4.6e-09 | 26.52 | In-house | 147-198 (347) | Show / Hide |
Range on Protein: 603-654 Range on HMM: 147-198/347 Sequence Identity: 44% (23 aa) VKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFEL .|| | | .| . . || | ||| |.|.. | || | || | | || IKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAEL |
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Kinase | SRPK.AA | PRP4 | 604-661 | 37 | 5.5e-09 | 29.1 | In-house | 147-205 (320) | Show / Hide |
Range on Protein: 604-661 Range on HMM: 147-205/320 Sequence Identity: 37% (22 aa) KIADLGNACWV-DRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLF |. | | | . . | . | ||. |.||| | . |.||..| .||.|| .| KMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMF |
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Kinase | SRPK.AA | DYRK2 | 735-763 | 37 | 1.2e-07 | 20.64 | In-house | 290-318 (318) | Show / Hide |
Range on Protein: 735-763 Range on HMM: 290-318/318 Sequence Identity: 37% (11 aa) SFASFLTPMLEFDPNKRATAAECLQHPWL .|. |.. .| || .| |... |.|||. NFIDFIKRCFEWDPSERMTPSQALKHPWI |
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Kinase | SRPK.AA | DyrkP | 282-311 | 53 | 6.4e-07 | 18.1 | In-house | 111-139 (323) | Show / Hide |
Range on Protein: 282-311 Range on HMM: 111-139/323 Sequence Identity: 53% (16 aa) ITRQVLEGLDYLHTCCKIIHTDIKPENVLL || |.| .|||.| ..|| |.||||.|. ITQQILIALDYIH-SLRLIHCDLKPENILM |
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Kinase | SRPK.AA | TyrKc | 170-382 | 13 | 2e-06 | -119.91 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 170-382 Range on HMM: 1-280/280 Sequence Identity: 13% (42 aa) YHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTV-RETDPSNPRRHKTVQMLDDFKITGVNG---------THICMVFE-VL . ..||| |.| .|... ||.| .|. | ..|..|.. . .|. . .. || ...|.| . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGG--------HHPNI-----VRLYGVCTQQGRNFMYIEPLMIVMEYMP GDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVR------SLATEAT-------QLYCM----NSKM------ . .|.. .||. . .... . |. .| .||| ..|| |. |.|. . .|. | . . . | . ..|. HGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW ----------------------------------YPS----------LVSRAPKEYREPPITG-------KMSKNRKKKL-----KKKAKKRMELFKQQR || .. . . || |. ... . . . ....| |.. . MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPT-FSEIH DYL ... ECF |
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Kinase | SRPK.AA | DyrkP | 736-763 | 46 | 2e-06 | 16.2 | In-house | 296-323 (323) | Show / Hide |
Range on Protein: 736-763 Range on HMM: 296-323/323 Sequence Identity: 46% (13 aa) FASFLTPMLEFDPNKRATAAECLQHPWL | | .| | .| || | |||||. FIDFVRQCLQIDFTRRPTAKEALQHPWF |
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Kinase | SRPK.AA | YAK | 736-763 | 28 | 8e-06 | 15.26 | In-house | 320-347 (347) | Show / Hide |
Range on Protein: 736-763 Range on HMM: 320-347/347 Sequence Identity: 28% (8 aa) FASFLTPMLEFDPNKRATAAECLQHPWL | |.. .|. .|..| .. ||| . FIDFINQLLQLNPRERWKPMQAMQHPFI |
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Kinase | SRPK.AA | DYRK1 | 729-763 | 34 | 1.2e-05 | 15.23 | In-house | 287-321 (321) | Show / Hide |
Range on Protein: 729-763 Range on HMM: 287-321/321 Sequence Identity: 34% (12 aa) SQKDAASFASFLTPMLEFDPNKRATAAECLQHPWL | .| | . ||..||..| | . |||... SVEDYLKFKDLIKRMLQYDPKQRITPYYALQHSFF |
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Kinase | SRPK.AA | PRP4 | 739-763 | 44 | 1.7e-05 | 16.14 | In-house | 296-320 (320) | Show / Hide |
Range on Protein: 739-763 Range on HMM: 296-320/320 Sequence Identity: 44% (11 aa) FLTPMLEFDPNKRATAAECLQHPWL .| .| || || | | |.|| . LLDKCLMLDPKKRITCNEALKHPFI |
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Kinase | SRPK.AA | HIPK | 603-654 | 35 | 2e-05 | 12.52 | In-house | 144-196 (329) | Show / Hide |
Range on Protein: 603-654 Range on HMM: 144-196/329 Sequence Identity: 35% (19 aa) VKIADLGNACWVDRHFTED-IQTRQYRSLEVIIGAGYNTSADIWSTACMVFEL ||. | | | | . .. .| | || |.|.| .. . |.|| | . || VKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAEL |
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Kinase | SRPK.AA | DyrkP | 170-219 | 30 | 8.3e-05 | 11.01 | In-house | 1-50 (323) | Show / Hide |
Range on Protein: 170-219 Range on HMM: 1-50/323 Sequence Identity: 30% (15 aa) YHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILK | .. || || | |.| . .||. . . . ||||.|. YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLR |
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Kinase | SRPK.AA | HIPK | 718-763 | 32 | 0.000302 | 8.73 | In-house | 284-329 (329) | Show / Hide |
Range on Protein: 718-763 Range on HMM: 284-329/329 Sequence Identity: 32% (15 aa) LMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWL |.| . | . | .| . | |. |..|| | .| |.||. LVDPERQDYRVEKIDRREFVHVLKKMCTWDAHKRITPCEALNHPFV |