Gene Src64B (Fruit Fly)

Src64B

Species: Fruit Fly
Alias: src64, DSrc64B, HD-358, Dsrc, c-src, CG7524, src1, D-src, DSrc64, dsrc, DmHD-358, SFO087, Dm SRC1, Src, DSRC64, src, dSrc, Src64, Dsrc64B, Dsrc64, Src64B, DSrc, SRC 64B, Src1, C-src1
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 64B12--13,

Classification

Group: TK
Family: Src
Subfamily: Src-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
Src64B.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 253 Kinase domain by global Sugen HMM Fasta, JSON
Src64B.AA Protein Various 552 None Fasta, JSON

Protein domain

Protein domains of Src64B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3_1 Src64B.AA SH3_1 101-148 44 4.1e-24 84.16 Pfam 1-49 (49) Show / Hide 
Range on Protein: 101-148
Range on HMM: 1-49/49
Sequence Identity: 44% (22 aa)

VALYDYKSRDESDLSFMKGDRMEVIDDTES-DWWRVVNLTTRQEGLIPL
||||||. .....|||.||| ..||..... |||.. ...|.|||..| 
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3 Src64B.AA SH3 98-155 39 1.5e-23 85.46 SMART 1-58 (58) Show / Hide 
Range on Protein: 98-155
Range on HMM: 1-58/58
Sequence Identity: 39% (23 aa)

RVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEER
..|.|||||..... .||| ||| ..|.......||.. . .| |||..| |.|.| .
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 Src64B.AA SH3_2 99-154 23 3.2e-10 38.69 Pfam 1-68 (68) Show / Hide 
Range on Protein: 99-154
Range on HMM: 1-68/68
Sequence Identity: 23% (16 aa)

VVVALYDYKS-RDESD-----LSFMKGDRMEVI---DDTESDWWRV-VNLTTRQE--GLIPLNFVAEE
..... ||.. .....     |.| |||  .||   |    .||..  .......  |..| ..|.| 
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 Src64B.AA SH2 162-244 51 2.4e-46 137.87 Pfam 1-81 (81) Show / Hide 
Range on Protein: 162-244
Range on HMM: 1-81/81
Sequence Identity: 51% (43 aa)

WFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAY
|.. .. |.|| .||....||.||||||.|| .|..|.|||.|. .  |..||||||. .|||||||.....|.||| ||. |
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP--GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 Src64B.AA SH2 160-250 45 5.2e-36 126.86 SMART 1-87 (87) Show / Hide 
Range on Protein: 160-250
Range on HMM: 1-87/87
Sequence Identity: 45% (42 aa)

EDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIAT--NQTFPSLQALVMAYSKNALG
. |.. |. |.||..||.....| |.||||.||.||..|.|||..       .||||||...|.|.|||..  . .||||  ||  |..|.||
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-----GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase Src64B.AA Src-Unclassified 284-536 61 2.1e-219 735.19 In-house 1-284 (284) Show / Hide 
Range on Protein: 284-536
Range on HMM: 1-284/284
Sequence Identity: 61% (175 aa)

IQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREG---TMSTAAFL--------QEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGD
..||||||||.||||.|||||...||||||.|.|   |||..|||        |||.||||.||..||.||||||||||.||..|||..||||..||||.
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

GRYLHFEDL------------IYIATQVASGMEYLESKQLIHRDLAARNVLIGENN-----VAKICDFGLA--RVIADDEYCPKQGSRFPVKWTAPEAII
|.|||..|.            ..||.||||||.|||||...||||||||||||.||     |.|.||||||  ....||.||...|..||.||.|||..|
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQ-LLLQCWDAVPEKRPTFEFLNHYF
||.||||||||||||||.|..|.||.||||||.|||.|..|||.|||||||||.||.||. ....||...|..||||..|.|||
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase Src64B.AA Src 284-536 64 1.5e-186 626.06 In-house 1-255 (255) Show / Hide 
Range on Protein: 284-536
Range on HMM: 1-255/255
Sequence Identity: 64% (167 aa)

IQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLR-EGDGRYLHFEDLI
|.|.||||.|.||||..|.|.....||||||..||||..|||||| ||||.||..||.||||||||||||||.||||.|||||.|. .|.||.||...||
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

YIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIA--DDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVP
..|.|||.||.||||...|||||||||||.|||||.|..||||||.|   |||||...|..||.|||||||| ||.|.|||||||.||||.|..|||.||
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMHSREVIENIERGFRMPKPTNHYFPDNIYQ-LLLQCWDAVPEKRPTFEFLNHYF
||||. .||....|||.|||.|.|  .||..|. ..||||.. ||.|||||.|....
YPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Src64B.AA SFK-Src 284-540 55 3.2e-156 466.9 In-house 1-259 (259) Show / Hide 
Range on Protein: 284-540
Range on HMM: 1-259/259
Sequence Identity: 55% (144 aa)

IQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIY
|.| .||| | ||.|. |.| |. .||||||. |.||   |||||..||| || .|. |||||   |||||. | |  |||||.|.|  || |    |. 
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

IATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIA-DDE-YCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPY
 | |||.|| ||| .  .||||||||||.|.||| |. |||..||.| ||| | ...| .||.|||||||  . .|||||||||.|||.||. ||| .||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMHSREVIENIER--GFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFS
|||   ||.  ..|  | |||.|.|   ||  |.....||   |. ||||| |    | | 
PGMTNMEVLQQVDRPEGYRMPCPPN--CPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase Src64B.AA TyrKc 284-536 47 1.6e-145 490.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 284-536
Range on HMM: 1-280/280
Sequence Identity: 47% (135 aa)

IQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKF--RHNRLVALYAVCSQE-------EPIYIVQEYMSKGSLLDFLREGDGR
|.|..|||.|.||||. |.|.  |.||||.|.|..   ..|..|| ||.|.  .|  .|.||.||.|.       ||..|| |||..|.|.|.||.  ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

YLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADD--------EYCPKQ--GSR--FPVKWTAPEAIIYGKFSIKSD
 |  .||.....|.|.|||||.||..|||||||||.|.|||...||.||||.| | ||         | .|.  |..  .|..|.|||.| ||||..|||
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSYGILLMELFTYGQVPYPG-----MHSREVIENIERGFRMPKPTNHY------FPDNIYQLLLQCWDAVPEKRPTFEFLNHYF
|||.|... |.||||| ||||     |  .||||....|.|||.| |.|       || .||. .|||.. ||.||||. . ..|
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Src64B.AA Pkinase_Tyr 284-536 52 9.60000000001e-143 484.06 Pfam 1-270 (270) Show / Hide 
Range on Protein: 284-536
Range on HMM: 1-270/270
Sequence Identity: 52% (143 aa)

IQLLRKLGRGNFGEVFYGKWR-----NSIDVAVKTLREGTMST----AAFLQEAAIMKKF-RHNRLVALYAVCS-QEEP--IYIVQEYMSKGSLLDFLRE
|....|||.|.||||. |.|.     . |.||||.|.||.|.     ..|..||.|||.. .|  .| ||.||. |.||  |||| ||| .|.|||.||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

G--DGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI-ADDEY-CPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSY
   |.. |  .||. ...|.|.||||||||..|||||||||.|..||||.||||||||| |  ||.|   ..|...|.||.|||.| ||||..||||||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLMELFTYGQVP-YPGMHSREVIENI-ERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYF
|.|. |.||||. | ||||   ||.| | |.| |||.|  .. || ||.|..|||.. ||.||||. . . .
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCP--ENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Src64B.AA SrcA 284-536 59 1.6e-138 440.61 In-house 1-250 (250) Show / Hide 
Range on Protein: 284-536
Range on HMM: 1-250/250
Sequence Identity: 59% (150 aa)

IQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIY
|.| |.||.| ||||. | |  .  ||.|||. ||||  |||.|| |||| ||..|| |||| | ||||||| |||.||||||||....|.||.  .|. 
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVS-EEPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

IATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPG
.| |||.|| |.|    ||||| | |.|.||| . || ||||||.| |.|| ..||..||.||||||| .||.| |||||||.|||| || | | |||||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG

MHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYF
|  |||.| .|||..|| | .   |  ...|. |||   || |||||.|  . 
MNNREVLEQVERGYHMPCPQD--CPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase Src64B.AA Frk 284-540 55 7e-125 421.17 In-house 1-260 (260) Show / Hide 
Range on Protein: 284-540
Range on HMM: 1-260/260
Sequence Identity: 55% (145 aa)

IQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLR--EGDGRYLHFEDL
|||.|.|| | ||||. |.| |.. ||||||. |||    ||.|| |||| || .|. |||||  ||||||. | | .|||...|.  .. || .... |
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

IYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLAR-VIADDE--YCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQ
. .| |||.|| ||||.  |||||||||||.||.|. || |||||| .. |.|  |  ..| |||.|||||||. | ||.|||||||.||||.|. |||.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

VPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFS
.|||||  .||.. ...|.|||.|.|   | ..|...|.|| . |.|||||| |   .| . 
MPYPGMTNAEVLQMVDHGYRMPQPPN--CPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase Src64B.AA SrcB 284-537 54 2.7e-123 415.92 In-house 1-251 (251) Show / Hide 
Range on Protein: 284-537
Range on HMM: 1-251/251
Sequence Identity: 54% (138 aa)

IQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIY
..| .||| | ||||. | ..|.. |||||...||||  |||.|| .||.  |.||| |||| ..| ||||. ||| ||.|||||.  .|  |. . || 
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPG
.. |.| || |.| .  ||||| | |.|. |  . || ||||||.| |.||  . | .||.|||||||| .| | |||||||.||||||. |||..||||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

MHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFE
|   |||.|.|||.|||.| |   |. .|... .||   || ||||..|    .
MTNPEVIRNLERGYRMPRPDN--CPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase Src64B.AA Src-Echino1 284-536 54 1.1e-122 413.83 In-house 1-252 (252) Show / Hide 
Range on Protein: 284-536
Range on HMM: 1-252/252
Sequence Identity: 54% (138 aa)

IQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIY
 .. .|.|.|..|||. | |    .||||||.|.||| |.|| || .||| ||. .| .||||| .|||||| | ||.|.|.|.|..|... . .  || 
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPG
.  ..||||.||.|| ..||||||||||.|. || || ||||||.. .|.|| ||| ..|.|||||||..||.| |||||||.|||. |. |.|..||||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPG

MHSREVIENIERGFRMPKPTNHYFPDNIYQL-LLQCWDAVPEKRPTFEFLNHYF
|. |||.....||.||||.  |  || .|.. ...||   | .||||||| ..|
MMNREVLDQVDRGYRMPKM--HHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase Src64B.AA TK 284-536 27 2.2e-122 412.36 In-house 1-486 (486) Show / Hide 
Range on Protein: 284-536
Range on HMM: 1-486/486
Sequence Identity: 27% (135 aa)

IQLLRKLGRGNFG---EVFYGKWRNS--------------------------IDVAVKTLREG-TMSTAA--------------FLQEAAIMKKFR----
|.|..|||.|.||   ||. |.||.                           ..||||.|.|| .|| ..              ||.||..||...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HNRLVALYAVCSQE------------EPIYIVQEYMSKGS----LLDFLR--EGDGRY-----------------------------------------
 |  .| ||.||.|.            ||..|| |||..|.    |.|.||   ....                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------LHFEDLIY-------------------IATQVASGMEYLESK------QLIHRDLAARNVLIGENNV-----------AKICDFG----
           |.. ||..                   .. |.|.|||||.||      ...||||||||.|.|||||           .||.|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LARVI-ADDEYCPKQ------------------------GSRFPVKWTAPEAII---------YGKFSIKSDVWSYGILLMELFTYGQVPYPG-MH
    ||| |  ||.|. |.                        | ..|..|.|||..          ||||..||||||.|.|. |.|||||.||.| |.
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

S---------REVIENIER------------GFRMPKPTNHYFP--------------DNIYQLLLQCWDAVPEKRPTFEFLNHYF
.         .||.|...|            | ||..|   . |              . .|.|..|||.. ||.||||. | ...
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Src64B.AA SRM 285-537 49 9.79999999999e-120 402.26 In-house 2-253 (253) Show / Hide 
Range on Protein: 285-537
Range on HMM: 2-253/253
Sequence Identity: 49% (125 aa)

QLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGT-MSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIY
 | |||| | ||||. | |. .. ||.|  .    |  . . .|   ||| || ....|.||||  .|.||. | | ||.|. .||. |.. |   .|. 
TLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLD

IATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPG
.| ||| || |||... |||||||||||.|.||. |. |||||| | || | |  ... |.|||||||. |. .|.||||||.|||| |.|||||.||||
FACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPG

MHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFE
|   | .  |.||.||| |     | ... |.|.||   ||.||.|  |     
MTNHETFQQIDRGYRMPCPAE--CPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase Src64B.AA Tec 284-538 44 1.6e-116 393.4 In-house 1-254 (254) Show / Hide 
Range on Protein: 284-538
Range on HMM: 1-254/254
Sequence Identity: 44% (115 aa)

IQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFE-DLI
. ... ||.| || | .||||...|||.|...||.||   |..|| .|.|  | .|| || ||||. ||||| |||..|.||..|||  ..       |.
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

YIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYP
..  .|  ||.|||... ||||||||| |.|...| |. |||..| . ||.|    |. ||||| .||   | ..| |||||..|.|  | |. | .||.
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE

GMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFES
 |   ||.| . .|.|. .|  |  .. |||   .||   ||.||||. |    . 
NMSNSEVVEHVSQGHRLYRP--HLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase Src64B.AA S_TKc 284-536 26 8.9e-57 195.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 284-536
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

IQLLRKLGRGNFGEVFYGKWRN-SIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSK--GSLLDFLREGDG----RYL
 ..|||.|.| ||.|. .....    ||.| ..        ...| .|.|| .|  .| || |.   . .|.| ||..   |.|.|....  .    ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

HFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSI-KSDVWSYGILLMELFT
.  .  ... |.....||. |.. |||||   |.|. |  . |||||||||..                . ||| .   ...  |.|.|| |..| |...
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

YGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLN--------HYF
 |. |.|  .  .....|              ..   ... .|..  |||||| | |.         .|
-GYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase Src64B.AA Pkinase 284-536 25 3e-51 181.35 Pfam 1-293 (293) Show / Hide 
Range on Protein: 284-536
Range on HMM: 1-293/293
Sequence Identity: 25% (77 aa)

IQLLRKLGRGNFGEVFYGKWRNSID-VAVKTLREGTMST----AAFL-QEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKG----SLLDFLREGDG
....||.|.|.||.|. ...... . ||||...  . .     .... .|..|||...|   | || ..  .  ||.|.||. .|    .| |...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RYL--HFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVA----KICDFGLARV--IADDEYCPKQGSRFPVKWTAPEAII-YGKFSIKSDVW
. .    .... ...|...|.||. |.  |||||   |.|| .|..     ||||||||..  .  ...    |...   . ||| |  . . . |.|.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPW---YMAPEVIRGGQYYGPKVDMW

SYGILLMELFTYGQVPYPGM----HSREVIENIERGFRMPKPTNHYFP---------------------DNIYQLLLQCWDAVPEKRPT-FEFLNH-YF
|.|..| |... |. |.||     . .. .. |.|  . | . . . .                     ..  ...  |..  |.||||  . |.| .|
SCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF