Gene CG8726 (Fruit Fly)

CG8726

Species: Fruit Fly
Alias: SFO008, CG8726
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 44A2

Classification

Group: Other
Family: Slob

Sequence

Name Sequence Type Origin Length Description Download
CG8726.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 222 Kinase domain by global Sugen HMM Fasta, JSON
CG8726.AA Protein Various 646 None Fasta, JSON

Protein domain

Protein domains of CG8726.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PX CG8726.AA PX 17-122 26 6.5e-17 60.52 Pfam 1-120 (120) Show / Hide 
Range on Protein: 17-122
Range on HMM: 1-120/120
Sequence Identity: 26% (32 aa)

TQALSCEITAVQ-----EVAGHTEYLLRVWRGAS--NKNYWTVLRRYNDFDRLDKSLRV--SGIEL-PLPRKRIFGN---MRPEFIAERKQALQEYINAV
.. |.....  .        .|..|. ....  .   | .|.| |||.|| .| | |.    .. . |||.|..||.   . .||| .|.|.|..|...|
DHFLQVHVVDPETHKHYGDKMHYYYVYEIHMNTNPFQKKEWHVWRRYSDFHWLHKQLKRHFPMCIIPPLPPKHWFGRYNNFDEEFIEKRRQMLEQYLQRV

LMNPILAS-SLPAKRFVDPE
. .| |.. .   ..|  |.
CQHPELCNHCEVFHDFLHPD
PX CG8726.AA PX 17-122 17 2.2e-09 38.4 SMART 1-142 (142) Show / Hide 
Range on Protein: 17-122
Range on HMM: 1-142/142
Sequence Identity: 17% (25 aa)

TQALSCEITAVQ------EVAGHTEYLLRVWRGASN-KNYWTVLRRYNDFDRLDKSL--RVS----GIELP-LPRKRIFGN------------------M
.. . . ..  .          |. |. .. .. .| . .||| |||.||  |.. |  .      .. .| ||.| .|..                  .
DHIFIITVVEFFTHGKHYHDGKHYYYVYEIHTKTNNHVKMWTVYRRYSDFHWLHHQLKRHFPQEKRMCIIPPLPPKHWFVRYRYWMEHMSMMWWYSFNNF

RPEFIAERKQALQEYINAVLMNPILAS----SLPAKRFVDPE
 ..|| .|.. |..|..... .|....    .   ..| ...
DEDFIEKRRRGLERYLQRLCHHPEWINHYMVCEVVYEFFESS
Kinase CG8726.AA Slob 152-169 33 0.000794 8.97 In-house 1-18 (268) Show / Hide 
Range on Protein: 152-169
Range on HMM: 1-18/268
Sequence Identity: 33% (6 aa)

MGAIGWRLRKHYFKVTTK
.. ||||.|| .. .. .
LDHIGWRHRKNWCMMKND
Kinase CG8726.AA Slob 209-432 49 3.4e-145 488.67 In-house 19-268 (268) Show / Hide 
Range on Protein: 209-432
Range on HMM: 19-268/268
Sequence Identity: 49% (123 aa)

LDPGSEVVAEWLEYGPD----KFIDEKEIGGIMKSLMGLQHPHIEPVL----LAAHTENGCLVIRKFHKHGTLKDVLCMAANPKNTFLSKYGN-------
..||.|.|..|..||||    |...|||....||.||...||.|.||.    ...|..|.|.|||.|.|.|.|||....|. ||.....||.|       
MQPGEECVQSWIDYGPDCCPWKMLNEKECQCFMKILMSCHHPYIYPVINLVFFINHKHNYCCVIRFFNKRGSLKDFIYKAK-PKMPWARKYCNKQPKSSS

---------PKGRTALSMKQVATYGKQILEALIFLHSKGYAYGHLHSGNIVIVD--DCVKLLDIENFLLGVPAFYRPFFMQHSKIHAIETIDVYCFGHVL
         .|....|.||||..|..|||||||||||||..||||||||..|.|  ||..|.||||.|||.|.||....|.|.|||.||..|||||||.|
SSSSSSSSSHKKQNGLPMKQVQKYCRQILEALIFLHSKGFPYGHLHSGNVMIDDSNDCCRLSDIENCLLGMPPFYNDYIMWHRKIHEIENVDVYCFGHCL

FEMAMGYPLQESVVRQITECP-EALKCLLESILSKEACKAGLPTLEQLLGH
.||..|||.|...||....|| .||.|..|.|||.|.||...||..|||  
YEMCCGYPMQNHSVRNFPPCPFIALFCDKEHILSCEICKHCMPTMRQLLQM
Kinase CG8726.AA S_TKc 227-435 17 5.6e-07 -74.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 227-435
Range on HMM: 1-231/231
Sequence Identity: 17% (45 aa)

FIDEKEIG---------GIMKS--------------------LMGLQHPHIEPVLLAAHTENGCLVIRKFHKH--GTLKDVLCMAANPKNTFLSKYGNPK
.   ..||         .. |.                    |.  .||.|   . . .. .   ..  .  .  |.|.|...           |.| ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIK-----------KRGRHG

GRTALSMKQVATYGKQILEALIFLHSKGYAYGHLHSGNIVIVDDCVKLLD-----IENFLLGVPAFYRP---FFMQHSKIHAIE-TIDVYCFGHVLFEMA
.|  ..  ... | .||..|| ..||.|  .  |   || . . ..|. |     .    . .  .|..   .       .     .|.. .| .|.||.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEML

MGYP---LQESVVRQITECPEALKCLLESILSKEACKAGLPTLEQLLG-------HRFF
 |||    .. . ..|   .. .| ... .| |.  |   ||  ..|        | .|
CGYPPFPQMQMMFKKIG--SPEAKDFIRKCLQKDPEK--RPTA-EALQDEWDIKCHPWF
Kinase CG8726.AA MLCK 304-325 27 0.000153 7.33 In-house 98-119 (257) Show / Hide 
Range on Protein: 304-325
Range on HMM: 98-119/257
Sequence Identity: 27% (6 aa)

QVATYGKQILEALIFLHSKGYA
.|..| .||.|.. ..|.....
EVIHYMRQICEGVHHMHWQNIV
Kinase CG8726.AA Aur 303-323 42 0.000171 7.22 In-house 101-121 (257) Show / Hide 
Range on Protein: 303-323
Range on HMM: 101-121/257
Sequence Identity: 42% (9 aa)

KQVATYGKQILEALIFLHSKG
.. |.| .|| .||...|||.
QRAAKYMYQICNALDYCHSKN
Kinase CG8726.AA CDK-Unclassified 297-323 37 0.00025 9.99 In-house 115-141 (324) Show / Hide 
Range on Protein: 297-323
Range on HMM: 115-141/324
Sequence Identity: 37% (10 aa)

RTALSMKQVATYGKQILEALIFLHSKG
|  ||| |.  . .|.|| . .||...
RYNLSMCQIRNFMHQMLEGIAYLHCNK
Kinase CG8726.AA Ciliate-E2-Unclassified 300-390 17 0.000565 9.7 In-house 135-268 (352) Show / Hide 
Range on Protein: 300-390
Range on HMM: 135-268/352
Sequence Identity: 17% (24 aa)

LSMKQVA-----TYGKQILEALIFLHSKG-YAYGHLHSGNIVIVDD----CVKLLDIENFL---------------------------LGVPAFY----R
.. .|..     .| .|||..| .||.|.   .  .   ||.. ..    ..|. |  ..                             | | .      
FTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTA

PFFMQHSKIHAI--ETIDVYCFGHVLFEMAMGYP
|  .|  .      . .|....| .|.|| .||.
PEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY
Kinase CG8726.AA CMGC 300-345 19 0.000788 7.44 In-house 179-247 (513) Show / Hide 
Range on Protein: 300-345
Range on HMM: 179-247/513
Sequence Identity: 19% (14 aa)

LSMKQVATYGKQILEALI--FLHSKG--YAYGHLHSGNIVIVDDC---------------------VKLLD
... ..  | .|||..|   ..||..       |   || | ..|                     .|. |
FMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICD