Gene CG1951 (Fruit Fly)
CG1951
Sequence
Protein domains of CG1951.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | CG1951.AA | SCY1 | 46-314 | 31 | 2.3e-130 | 439.4 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 46-314 Range on HMM: 1-337/337 Sequence Identity: 31% (107 aa) WKVYNGHKKSTKQEVSVFVFEKKSLERWSKDDRETMLETLRRG-VQQLTKIRHPHVLTVQHPLEESRDSLAFATEPVFASLANVVG--DNVRS------- ||..||.||.|.||.|||||.||..|.|.||..... ...... ...|...|||..|...||||||.|....|||..|..|.||.. ||..| WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQKTQ -----------------EKKLYDVEIRHGLLQLFDGLQFLHQDAKIVHRNISAETIVINKNRSWKLFG---------FDFCIANQPATDGTPHWPFREY- ..||...|...|..|..|.|.|||.|...||.||..|.|..|||..||..| .||....|......|..|..|. DVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFPCQEWR ------------TTSLHVLAQPSLEYTAPELALN-------------SVNTPDSDLFSLGVLIFTIY-AGKPLKMFGSD-YSSFRRYANDLNQRKYPPMN .. .. ..||.....||| ... ...|..||.||||.||...| .||.....|. ||.|.||....|........ EMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWNAMSHCWWD AVPSELTES----LKALLHPSANLRPKLHELKQIAYF .|.||.|. ..|||.....||......|..|| HIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF |
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S_TKc | CG1951.AA | S_TKc | 34-314 | 17 | 3.1e-13 | 17.11 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 34-314 Range on HMM: 1-231/231 Sequence Identity: 17% (50 aa) LEQVCTAGVGLMWKVYNGHKKSTKQEVSVFVFEKKSLERWSKDDRETMLETLRRGVQQLTKIRHPHVLTVQHPLEESRDSLAFATEPVFA---SLANVVG | . . | | . ||| ...|.|...| . . |..|| .| | | .||.. . .. |.| . .| . .| . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIK DNVR--SEKKLYDVEIRHGLLQLFDGLQFLHQDAKIVHRNISAETIVINKNRSWKLFGFDFCIANQPATDGTPHWPFREYTTSLHVLAQPSLEYTAPELA .. | ... ..|. . |....|...|. .|.|| . | | ... |. | .. . . ...| |||. KRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------------------TTFCG-TPWYMAPEVL LNSVNTPDSDLFSLGVLIFTIYAGKPLKMFGSDYSSFRRYANDLNQRKYPPMNAVPSELTESLKALLHPSANLRPKLHELKQ-------IAYF . ... .| |.|.... ..|.|. .. |.. ..|. . .. .|. . || |. | .| --GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | CG1951.AA | Ciliate-E2-Unclassified | 130-254 | 19 | 8.3e-10 | 30.23 | In-house | 126-268 (352) | Show / Hide |
Range on Protein: 130-254 Range on HMM: 126-268/352 Sequence Identity: 19% (31 aa) GDNVRSEKKLYDVEIR-----HGLLQLFDGLQFLHQDAKIVHRNISAETIVINKNR---SWKLFGFDFCI---------------------ANQPATDGT ..| .. |.. . ... . . |. .||..||. .|.||.| | |....| |. .| ... .. . || FHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGT PHW-PFREYTTSLHVLAQPSLEYTAPELALNSVNTPD----SDLFSLGVLIFTIYAGKP | | . |||||. . . .| .||||... . |.. PNYMP-Q---------------YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY |
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Kinase | CG1951.AA | AGC | 221-314 | 18 | 2e-06 | 10.83 | In-house | 272-395 (395) | Show / Hide |
Range on Protein: 221-314 Range on HMM: 272-395/395 Sequence Identity: 18% (24 aa) EYTAPELALNSVNTPDSDLFS--LGVLIFTIYAGKPLKMFGSD---------YSSFRRYANDL-------NQRKYPPM--------NAVPSELTESLKAL || ||| .. | | ||.|.. .|.| | .| .. . . . . .. |.|. . .|. .| | EYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPP--FYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKL LHPSANLRPK----------LHELKQIAYF |.. . |. |.|. .| LCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | CG1951.AA | Dicty3 | 132-189 | 16 | 1e-05 | 14.61 | In-house | 101-184 (351) | Show / Hide |
Range on Protein: 132-189 Range on HMM: 101-184/351 Sequence Identity: 16% (14 aa) NVRSEKKLYDVEIRHGLLQLFDGLQFLHQDAKIVHRNISAETIVINKNRS--------------------------WKLFGFDF .... ... . ||. . .| .| ..| . .|.||.| . |....... |||..|.. KKHKNNRFNEHEISKIICDLVKTLNYIHKNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGL |
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Kinase | CG1951.AA | Pkinase | 219-314 | 14 | 1.5e-05 | 20.71 | Pfam | 174-293 (293) | Show / Hide |
Range on Protein: 219-314 Range on HMM: 174-293/293 Sequence Identity: 14% (18 aa) SLEYTAPELAL-NSVNTPDSDLFSLGVLIFTIYAGKPLKMFG----SDYSSFRRYANDLN---QRKYPPMNAVP-----------------SELTESLKA ...| |||. . .. .| .| .|.|.... . |.|. . .. ...... . .| . .. .|. . .| TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW LLHPSANLRPKLHELKQIAYF .|.. . || ....| .| CLCKDPKKRPTAEQILQHPWF |
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Kinase | CG1951.AA | Ciliate-E9 | 149-179 | 38 | 3.1e-05 | 12.25 | In-house | 118-148 (298) | Show / Hide |
Range on Protein: 149-179 Range on HMM: 118-148/298 Sequence Identity: 38% (12 aa) LQLFDGLQFLHQDAKIVHRNISAETIVINKN .|| |. ..|| | || . | ..|.|| KQLIDSIEYMHQYQNICHRDLKPENMLIDKN |
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Kinase | CG1951.AA | Ciliate-E7 | 135-195 | 32 | 5.6e-05 | 13.8 | In-house | 92-151 (290) | Show / Hide |
Range on Protein: 135-195 Range on HMM: 92-151/290 Sequence Identity: 32% (20 aa) SEKKLYDVEIRHGLLQLFDGLQFLHQDAKIVHRNISAETIVINKNRSWKLFGFDFCIANQP |. | | |. . | | ..| .||.| . | || | . | .| ||.|.| SRQQLTDEHIKWFMYQILRALHYIHS-QKIYHTQLTPRFIQINQNCDIKISDFIWCIGNFP |
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Kinase | CG1951.AA | Ciliate-E2 | 150-314 | 13 | 9.2e-05 | 12.26 | In-house | 168-365 (365) | Show / Hide |
Range on Protein: 150-314 Range on HMM: 168-365/365 Sequence Identity: 13% (30 aa) QLFDGLQFLHQDAKIVHRNISAETIVINKNRSWKLFGFDFC-IANQPATDGTPHWPFREYTTSLHV---LAQP----------------SLEYTAPELAL .. ..|..||. .|.||.| | |.. |. | .. ..... ..| . .. . .. . ...| ||| CIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILN NSV---------NTPDSDLFSLGVLIFTIYAGKPLKMFGSDYSSFRRYANDLNQRKYPPMNA-----------------VPSELTESLKA----LLHPSA . . .|..||||... ||| . . ... | . .. | .| .| GKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDP NLRPK-LHELKQIAYF . |. .... .| EKRITGWEQILNHPWF |
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Kinase | CG1951.AA | RSKL | 222-256 | 27 | 0.000243 | 4.6 | In-house | 344-378 (436) | Show / Hide |
Range on Protein: 222-256 Range on HMM: 344-378/436 Sequence Identity: 27% (10 aa) YTAPEL-ALNSVNTPDSDLFSLGVLIFTIYAGKPLK |.||| . . |. .| |.|.. . |..|. YCAPEVGQI-WELTEACDWWSYGAVLYELLCGMSLY |
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Kinase | CG1951.AA | Dicty1 | 148-191 | 35 | 0.000265 | 10.29 | In-house | 140-183 (327) | Show / Hide |
Range on Protein: 148-191 Range on HMM: 140-183/327 Sequence Identity: 35% (16 aa) LLQLFDGLQFLHQDAKIVHRNISA-ETIVINKNRSWKLFGFDFCI | || .. |.| | ..|| . || ...| ||. | ||. LYQLLMTIKFMHS-AGVIHRDLDPENTIFVDQNYCIKLTEFYFCF |
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Kinase | CG1951.AA | NZAK | 219-254 | 27 | 0.000821 | 8.12 | In-house | 235-270 (329) | Show / Hide |
Range on Protein: 219-254 Range on HMM: 235-270/329 Sequence Identity: 27% (10 aa) SLEYTAPELALNSVNTPDSDLFSLGVLIFTIYAGKP . .| ||| |. . || .|.|.... . . | THHYMAPENKNNHRINEKSDVWSFGCTVWQMFGYNP |
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Kinase | CG1951.AA | NZAK | 148-187 | 25 | 0.001299 | 7.44 | In-house | 111-149 (329) | Show / Hide |
Range on Protein: 148-187 Range on HMM: 111-149/329 Sequence Identity: 25% (10 aa) LLQLFDGLQFLHQDAKIVHRNISAETIVINKNRSWKLFGF .. . .. .||. .|.|| | .. ..|. || | IADIAETMSYLHKH-HIIHRDIKSNNVILDFNKNLKLIDF |
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Kinase | CG1951.AA | Pkinase | 75-167 | 18 | 0.01351 | 10.26 | Pfam | 35-132 (293) | Show / Hide |
Range on Protein: 75-167 Range on HMM: 35-132/293 Sequence Identity: 18% (19 aa) KDDRETMLETLRR--GVQQLTKIRHPHVLTVQHPLEESRDSLAFATEPVFASLANVVGDN----VRSEKKL--YDVEIRHGLLQLFDGLQFLHQDAKIVH ..... ...|.|| .| . ...||.... . |. .|.. . .| . | | ....... . |... ..|.. ||...|. .|.| RHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIH R | R |