Gene Drl-2 (Fruit Fly)

Drl-2

Species: Fruit Fly
Alias: CG3915, dnl, CG12463, SFO017, Drl-2, doughnut-like, DNT-like
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 49F3--4

Classification

Group: TK
Family: Ryk

Sequence

Name Sequence Type Origin Length Description Download
Drl-2.AA Protein Various 562 None Fasta, JSON
Drl-2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 257 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of Drl-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
WIF Drl-2.AA WIF 38-169 37 1.5e-66 228.77 Pfam 3-145 (145) Show / Hide 
Range on Protein: 38-169
Range on HMM: 3-145/145
Sequence Identity: 37% (54 aa)

LSLRPVGSFIPAGLEADLFYVHEGAINTYAMH-----F------TVPVPADVHELEFSWQSLIAYPLPYAISIEYNNDQEALGTPTLSIPHKGLVPQEIE
.. . |  .|  |..|...|.|.|..|.||..     |      ..|||..||...|.||||......|.....|..||.....|||.|.|.| ||.|..
INEHQVMMLI--GVSAEIYYIHNGHVNHYAHDPNFSHFRKAQQRMPPVPSNVHYVNFTWQSLGKHKYHYNFQVLYSSDQQIMKRPTLNISHQGRVPHEAK

SFLVYLPCTGNASLQMPVNVNMVVRAPPRF--NDTRLHFKRNKIC
.| ..|||.||.|.|....||..|......  |.|.|.|||.|||
EFSIDLPCSGNRSGQATFTVNLEVMHRRSKPNNNTPLRFKRKKIC
WIF Drl-2.AA WIF 35-171 31 4.1e-33 117.25 SMART 1-146 (146) Show / Hide 
Range on Protein: 35-171
Range on HMM: 1-146/146
Sequence Identity: 31% (47 aa)

HPQLSLRPVGSFIPAGLEADLFYVHEGAINTYAMHF------TVPVPADVHELEFSWQSLI-AYPLPYAISIEYNNDQEALGTPTLSIPHKGLVPQEIES
|  . . ..      |..|.|.|| ||.|| ||  |       .||||..| . | ||..  | ...| |...   |||... |.. |||.| ||...  
HVNMWINKHEMRRLIGVDAELYYVREGHINHYAHNFRKAQQRMYPVPANIHYMHFTWQAVGQAHYVHYFINVQ-SDDQEVMPMPIVNIPHQGTVPHTLQV

FLVYLPCTGNAS--LQMPVNVNMVVRAP-PRFNDTRLHFKRNKICAK
. | ..|.|  .   .  |.... |       | | | |.| |||..
WQVEYKCSGHRDGVAEFMVTMYVMVKYNRSTKNFTHLNFRRKKICYQ
Kinase Drl-2.AA Ryk 295-551 50 3.8e-210 671.06 In-house 1-292 (292) Show / Hide 
Range on Protein: 295-551
Range on HMM: 1-292/292
Sequence Identity: 50% (148 aa)

LSYEELVKEGTFGRIYAGKLG------------------ESCEALVKTVIDGASLTQVACLLQDASLLIGVS-HQHILAPLLAN--------TELPGPPE
..|..||.||||||||.|...                  ......||||.|.||..||.|.||...||.|.| ||.||..|...        .|...||.
IQYSCLVQEGTFGRIYHGIWNQVDDVNNGDVDDEEDTFCDCQDVFVKTVKDHASQMQVHCMLQESCLLYGISPHQNILPVLHVCSFGRFDRPIEDHDPPF

IAYPHPS-KGNLKMYLQKS----RESSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEE---SYVKICDSALSRDLFPDDYDCLGDNENR
..|||.. .||||..||..    .....|.||.|||.....||.|...||...|||||||||||..||.   ..||||||||||||||.||.||||||||
VCYPHMNNWGNLKQFLQDCRHDKPKCHQAISTHQLVHMAIQITMGMMHLHKHRIVHKDIATRNCVIDEQNGRLQVKICDSALSRDLFPMDYHCLGDNENR

PLKWLSLESLQKRVYATQGDVWALGVTYWELVTLAQMPHEEVDIFELTNYLAAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLSYL
|.||.||||||...|....|||..|||.|||.||.|||..|.|.||...||..|.||.||.|||||.||||.|||||....|||..||...|
PVKWMSLESLQHKHYSHASDVWSFGVTMWELMTLGQMPYMEIDPFEMYHYLKDGYRLQQPFNCPDELFTVMACCWHCMPEERPTFQQLVQCL
Kinase Drl-2.AA TK 295-551 17 4.8e-72 240.58 In-house 1-486 (486) Show / Hide 
Range on Protein: 295-551
Range on HMM: 1-486/486
Sequence Identity: 17% (84 aa)

LSYEELVKEGTFG---RIYAG--------------------------KLGESCEALVKTVIDGASLTQVACLL----------------QDASLLIG--V
. ...   || ||   ..| |                          | |. ..  ||.. .|.. .| . ..                . ....     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHQHILAPLLANTELP-----------GPPEIAYPHPSKGN----LKMYLQKSRESSTA-----------------------------------------
 |..|.  . . |.             .|. |   . ..|.    |. ||.|.|.  .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSTRQLVEFGLHITKGLAYLHSL------GIVHKDIATRNCYLDEESY-----------VKICDSA---
                               |...||. . . | .|..||||.      ..|| |.|.||| ..|.             .||.|     
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRDLFPDDYDCLGD------------------------NENRPLKWLSLESLQKRV---------YATQGDVWALGVTYWELVTLA-QMPHEEV
     |.||. .||. .  .                        .   |..|.. |.|..||         . |. |||..||. ||..|.. .......
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DI---------FELTNYLAAG--------------FRLEQPVNCP--------------DEFFTVMNCCWHCEAKQRPTPSQLLSYL
.           |. .|| .|              .|..||..||              .|.. .| .||| ....||| |||...|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Drl-2.AA Pkinase_Tyr 295-551 30 8.9e-66 223.39 Pfam 1-270 (270) Show / Hide 
Range on Protein: 295-551
Range on HMM: 1-270/270
Sequence Identity: 30% (83 aa)

LSYEELVKEGTFGRIYAGKLG-----ESCEALVKTVIDGASLTQ--VACLLQDASLLIGV-SHQHILAPLLANTELPGP--PEIAYPHPSKGNLKMYLQK
..  .   || ||..| |..      . ..  ||.. .||.  |   . ... |...    .|..|.  . . |.  .|  . |  ..  .|.|. ||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

SRESSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDLFPDDYD-CLGDNENRPLKWLSLESLQKRVYATQGDVWAL
 ||.  .|.. .|... . | ||..||.| ...| |.|.||| ..|.  |||||  |.||...|||    ...   | ||...|... ... |. |||. 
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GVTYWELVTLAQMP-HEEVDIFELTNYL-AAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLSYL
||. ||..|. ..|  .... .|. .|.   | |...| |||||  ..|  ||| ....||| |.... |
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Drl-2.AA TyrKc 295-551 28 5.6e-65 223.1 SMART 1-280 (280) Show / Hide 
Range on Protein: 295-551
Range on HMM: 1-280/280
Sequence Identity: 28% (82 aa)

LSYEELVKEGTFGRIYAGKLGESCEALVKTVIDGASLTQVACLLQDASLLIGV--SHQHILAPLLANTELP-------GPPEIAYPHPSKGNLKMYLQKS
.. ..   || ||..| |..    .  ||.. ..|    .. ... |...  .  .|..|.. |..    .       .|. |   . ..|.|| ||.|.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVR-LYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

RESSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDLFPD-------DYDCL--GDNEN--RPLKWLSLESLQKRVY
|.    |....|..| . | .| .|||| ...| |.|.||| ..|.  |||.|  ||||.  |       ||     .....   |..|...|.......
RPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

ATQGDVWALGVTYWELVTLAQMPHEE-----VDIFELTNYLAAGFRLEQPVN--------CPDEFFTVMNCCWHCEAKQRPTPSQLLSYL
 |. |||. ||. ||. |. |.|...     .. .|. .|. .|.|..|| |        |||| ...| .||| ....||| |.. ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Drl-2.AA TK-Unique 295-551 26 1.6e-55 189.93 In-house 1-294 (294) Show / Hide 
Range on Protein: 295-551
Range on HMM: 1-294/294
Sequence Identity: 26% (79 aa)

LSYEELVKEGTFGRIYAGKLGE-------SCEALVKTVIDGASLTQVACLLQDASLLIGVS-HQHILAPLLANT-ELPGPPEIAYPHPSKGNLKMYLQKS
|  .... || || .. |.. .          ..||.. |.|..|... .|. ....  .  |..|.  | . |    .|. |.... ..|||  ||...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTC

R---------------------ESSTA-LSTRQLVEFGLHITKGLAYLHS--LGIVHKDIATRNCYLDEESYVKICDSALSRDLF-PDDYDCLGDNENRP
|                     . .|. .| ..|. |.  | .|..||.|   .|||.|...||. | |   .||||  ..||.  . .|.  .  .  |
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP

LKWLSLESLQ--KRVY-ATQGDVWALGVTYWELVTLAQMPHEEVDIFELTNYLAAGFRLEQPVNC-PDEFFTVMNCCWHCEAKQRPTPSQLLSYL
..|...|||.  ...|  |..|||..||. ||..|| ..|  ...  .. . . .|.|..|| .| ..|.. .| .||. |...||. .|... |
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase Drl-2.AA Met 386-545 37 4.1e-48 155.67 In-house 95-271 (271) Show / Hide 
Range on Protein: 386-545
Range on HMM: 95-271/271
Sequence Identity: 37% (66 aa)

RESSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDL-FPDDYDCLGDNEN---RPLKWLSLESLQ---------KR
|  . ..  |.|.||.. . ||  |..|.  || | | ||| |||.  ||. |  |.||.     |    .       |.||. .|.||          |
RNPQNNPCVRDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHHTHPARLPVKWMAPECLQQGVCLGCPTYR

VYATQGDVWALGVTYWELVTLAQMPHEEVDI-FELTNYLAAG--FRLEQPVNCPDEFF-TVMNCCWHCEAKQRPTPS
.. |. |||  ||  ||| | .  |  .||  | .| .|. |   || ||  |||     || |||| .. .||. |
QFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEYCPDHLYTDVMLCCWHANPEDRPQFS
Kinase Drl-2.AA RTKB 376-551 32 5.7e-48 159.8 In-house 87-264 (264) Show / Hide 
Range on Protein: 376-551
Range on HMM: 87-264/264
Sequence Identity: 32% (59 aa)

GNLKMYLQKSRES-STAL--STRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDLFPDDYDCLGDNENRPLKWLSLESLQKR
|||  || ..| | . ..  . .|||.| . | .| |.||. ...| | . ||  .| .   |||| ...| .  ..|    .    | ||.  ||. .|
GNLRDYLRMCRASQHNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCT--RLPIKWMAPESWAHR

VYATQG-DVWALGVTYWELVTLAQMPHEEVDIFELTNYLAAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLSYL
 | |.  |||..||| ||  .|   |  .   ... ..|. |.||..|   | ... .|  ||  || .||. . |.. .
IYTTKSGDVWSFGVTMWEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase Drl-2.AA UTK 295-551 21 5.2e-47 158.87 In-house 1-296 (296) Show / Hide 
Range on Protein: 295-551
Range on HMM: 1-296/296
Sequence Identity: 21% (65 aa)

LSYEELVKEGTFGRIYAGKL-------GESCEALVKTVIDGASLTQVA---CLLQDAS---LLIGVS-HQHILAPLLANTELPGPPEIAYPHPSKGNLKM
.   ..  .| || .. ...       .|.  |. . . .... .. .    ..  |    ..  .. |...|  |..     .|. |.. . ..|.|  
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLR-LVGVCTQEEPWMIVTEYMENGDLRS

YLQKSRE----SSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEE-------SYVKICDSA---LSRDLFP--------DDYDCLGDNEN
||...|.      ..|. .|.... ..|  |..|||| |.|| |.| |||....        . .||.|     .||..          ..| .  .. .
YLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQD

R-PLKWLSLESLQKR-VYATQGDVWALGVTYWELVTLAQMPHEEVDIFELTNYLAAG--FRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLSYL
| |..| . |.| ..  . |. |||..||. ||..| ...| ..    ...  . .|   |...|  ||.. ...|. ||| .   ||.. .|.. .
RWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase Drl-2.AA Axl 366-549 38 2.9e-45 156.69 In-house 82-267 (267) Show / Hide 
Range on Protein: 366-549
Range on HMM: 82-267/267
Sequence Identity: 38% (71 aa)

PEIAYPHPSKGNLKMYLQKSR--ESSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDLFPDDYDCLGDNENRPLKW
| .  |    | |  .|  ||  .    | .  || | . |  |. || .   .|.|.| ||| | |.  | . |  ||. ..  ||   |     | ||
PMVILPFMKHGDLHTFLLYSRLGDQPFYLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGCIAKMPVKW

LSLESLQKRVYATQGDVWALGVTYWELVTLAQMPHEEVDIFELTNYLAAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLS
. .|||  |||  . |||| ||| ||..|  | |   |.  |. .||  | || ||..| || . .|  ||. . |.||. |.|  
IAIESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPEDCMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase Drl-2.AA EGFR 376-552 32 4.8e-45 147.41 In-house 85-258 (258) Show / Hide 
Range on Protein: 376-552
Range on HMM: 85-258/258
Sequence Identity: 32% (58 aa)

GNLKMYLQKSRESSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDLFPDDYDCLGDNENRPLKWLSLESLQKRVYA
|.|  |... ..   ..  ..|. ... | ||. ||    .|| | |.||  .   . ||| |  |.. | .|. .   .    | ||. ||....|.| 
GCLLDYVRQHKD---NIGSQHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQGGKMPIKWMALECIHHRCYT

TQGDVWALGVTYWELVTLAQMPHEEVDIFELTNYLAAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLSYLQ
 | |||. ||| |||.|  | |.. .   |  . |  | ||.|| .|    . ||  ||.  .. |||  .| . ..
HQSDVWSYGVTCWELMTFGQKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase Drl-2.AA FGFR 386-551 36 7.5e-39 130.03 In-house 119-293 (293) Show / Hide 
Range on Protein: 386-551
Range on HMM: 119-293/293
Sequence Identity: 36% (64 aa)

RESSTA--------LSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDLFPDDYDCLGDNENRPLKWLSLESLQKRVYATQ
| ..          |. ..|| .   . .|  || |  ..| | | ||    ..   ||||  |.||    ||     |   | ||  .|.|. ||| .|
RKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGRLPIKWMAPEALFDRVYTHQ

GDVWALGVTYWELVTLAQMPHEEVD-IFELTNYLAAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLSYL
 |||  ||  ||  |. . |   .  . ||  ||  | |.| | ||. | . .|  ||| ...||||  ||  ||
SDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase Drl-2.AA Trk 379-551 30 3.4e-37 123.57 In-house 100-275 (275) Show / Hide 
Range on Protein: 379-551
Range on HMM: 100-275/275
Sequence Identity: 30% (54 aa)

KMYLQKSR-ESSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDLFP-DDYDCLGDNENRPLKWLSLESLQKRVYAT
..|.|     . . |   |.      |. |. |. |. .|| |.|||||   ... ||| | ..|||..   ||  .|     |  |.  || . | . .
MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFTY

QGDVWALGVTYWELVTLAQMPHEEVDIFELTNYLAAGFR-LEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLSYL
  ||| .||. ||  |  . |       |  ..  .|   ||.|  || | . .|  ||. | .|| .  ..   .
ESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase Drl-2.AA S_TKc 295-551 17 6.6e-14 27.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 295-551
Range on HMM: 1-231/231
Sequence Identity: 17% (47 aa)

LSYEELVKEGTFGRIYAGKLGE-SCEALVKTVIDGASLTQVACLLQDASLLIGVSHQHILAPLLANTELPGPPEIAYPHPSK--GNLKMYLQKSRE--SS
    ... .|.||. | ..  .   .  .| .           ...  ..|    | .|   . .  .  .   .   . .   |.|. |..| .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

TALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDLFPDDYDCLGDNENRPLKWLSLESLQKRVYAT-QGDVWALGVTYW
  ..  .   .   | ..|.|.||.||.| |.   |  |||   .||||  |.| |    . . |      . ... | |    | .   |.|..|.. .
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCG-----TPWYMAPEVL---GYGKCKCDWWSCGCILY

ELVTLAQMPHEEVDIFELTNYLAAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLS---------YL
|...  . | .  ..... . .            ..|.   .. |.. . ..|||  ..|          ..
EMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Drl-2.AA Pkinase 386-438 28 1.2e-05 21.04 Pfam 97-155 (293) Show / Hide 
Range on Protein: 386-438
Range on HMM: 97-155/293
Sequence Identity: 28% (17 aa)

RESSTAL--STRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYV----KICD
.......  | ...  . . | .||.|.|| ||.| |.   |. .|.. ..    ||||
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICD
Kinase Drl-2.AA Pkinase 469-551 14 0.004643 11.9 Pfam 183-293 (293) Show / Hide 
Range on Protein: 469-551
Range on HMM: 183-293/293
Sequence Identity: 14% (16 aa)

LQ-KRVYATQGDVWALGVTYWELVTLAQMPHEEV-------DIFELTNYLAAGFRLEQPVNCP-------------------DEFFTVMNCCWHCEAKQR
..  . | .  |.|..|.. .|...  . |  .        ... . . . . .. . |  |.                   .|.  ....|..   |.|
IRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKR

PTPSQLLSY--L
||. |.|    .
PTAEQILQHPWF