Gene CG11859 (Fruit Fly)
CG11859
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| CG11859.AA | Protein | Various | 538 | None | Fasta, JSON |
| CG11859.kin_dom | Protein Kinase Domain | None | 8 | None | Fasta, JSON |
Protein domains of CG11859.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | CG11859.AA | RIO2 | 73-310 | 50 | 3.6e-137 | 462.02 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 73-310 Range on HMM: 1-260/260 Sequence Identity: 50% (132 aa) YRLTNTGYDYLALKSLTLRGSVSSFGNQIGIGKESNIYVVADEEGTPICLKLHRLGRTCFRNVKAKRDYHGRRHKASWLYLSRISATREFAYMSALYDRG ||||| |||||||| | | | | |||.|.|||| || ...|.| . .|.|||||| |.|.| .|||| .|| .||.|||| || |...|..|| |. YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHRHQYSWMYLSRLSAMKEYQFMDMLYKRN FPVPKPIDFNRHCVLMDLVKGWPMTQVHELLDAPQVYDDLMNLIVRLGNSGVIHGDFNEFNLMVTDAGK------PILIDFPQMMSTSHENAEFFFERDV |||||||| ||| | |.|. | || | |. . |.|||..| .|||| |.| ||.||||||||. | .. |.|||||| ||.| ||...|.||| FPVPKPIDYNRHIVVMELINGYPMCQIHHHDNPPYVYDQCMCFIVRLANHGLIHCDFNEFNLMIDDNDHDENDCGFIMIDFPQMVSTQHQNAQWYFDRDV NCVREMFRRKFGYESEDYP------------------KFSDLVREDDLDAEVHCTGYGFTKE |.. |...| ||.. .| | | |.| || || ||.|. DCIHRFFMKRFNYEPKPFPSMLDTEGFGDGYKYAYPDFFRDIQRTDTLDEEVQAS--GFNKK |
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| Kinase | CG11859.AA | RIO | 73-301 | 34 | 3.9e-100 | 338.99 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 73-301 Range on HMM: 1-276/276 Sequence Identity: 34% (94 aa) YRLTNTGYDYLALKSLTLRGSVSSFGNQIGIGKESNIYVVADEEGT-----------PICLKLHRLGRTCFRNVKAKRD---YHGRRHK-ASWLYLSRIS |..|| .|...... . || | | ||.||.||||.|| ...|.| . .|.||.||| |...| .|| |. || ..|.|..|.. YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW ATREFAYMSALYDRGFPVPKPIDFNRHCVLMDLVKG-------WPMTQVHELLDAPQVYDDLMNLIVRLGNSG-VIHGDFNEFNLMVTDAGK------PI | |...|..|| .|||.|.||| .|| . | . . || | ||. . . ||...| ...|| ... .|.||||||.|. | .. . AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY LIDFPQMMSTSHENAEFFFERDVNCVREMFRRKFGYESEDYPKFSDLV------------------REDDLDAEVH .|||||| ...| .|...| ||. ||. | ..| ||.. . . | | |.| ||.|. MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM |
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| Kinase | CG11859.AA | RIO1 | 108-287 | 33 | 1.4e-95 | 298.57 | Pfam | 1-200 (200) | Show / Hide |
Range on Protein: 108-287 Range on HMM: 1-200/200 Sequence Identity: 33% (67 aa) NIYVVAD-EEGT-PICLKLHRLGRTCFRNVKAKRDYHGR----RHKASWLYLSRISATREFAYMSALYDRGFPVPKPIDFNRHCVLMDLVK---GWPMTQ |.|.... |.|. ....|..|.|.|||...| .|||. | .|. .|.|..|..| .||......| .|.|.|||||.|||...|... |||. . NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR VHELL--------DAPQVYDDLMN--LIVRLGNSGVIHGDFNEFNLMVTDAGKPILIDFPQMMSTSHENAEFFFERDVNCVREMFRRKFGYE-SEDYPKF .... .|...||... ..... . |..|||..|.|..|.| ||| .||.||.....|..|..|.|||.... ..||||...| ..|.... LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI |
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| RIO | CG11859.AA | RIO | 66-289 | 21 | 2.5e-60 | 207.67 | SMART | 1-253 (253) | Show / Hide |
Range on Protein: 66-289 Range on HMM: 1-253/253 Sequence Identity: 21% (55 aa) RGKKYDGYRLTNTGYDYLALKSLTLRGSVSSFG--NQIGIGKESNIYVV----ADEEGTPICLKLHRLGRTCFRNVKAKRDYHGRRH----KASWLYLSR ..|..|... ......|... || ... . ..|. |||.|.|.. .|..|... | .|...|.|.... .... | . ...|....| DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR ISATREFAYMSALYDRGFPVPKPIDFNRHCVLMDLVKG--WPMTQVHELLDAP-------QVYDDLMNLIVRLGNSG-VIHGDFNEFNLMVT-----DAG ..| .|| .. .| |.|.||||...|| ..|... . ||. .. .. . . .|...| .... ... .|.|..|.|.... ... LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC KPILIDFPQMMSTSHENAEFFFERDVNCVREMFRRKFGYES----EDYPKFSD |. .||..| ....|. ...|.|||..... |||| .. |.. .. . KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG |
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| Rio2_N | CG11859.AA | Rio2_N | 9-91 | 60 | 2.4e-51 | 175.63 | Pfam | 1-84 (84) | Show / Hide |
Range on Protein: 9-91 Range on HMM: 1-84/84 Sequence Identity: 60% (51 aa) LRYLTKEDFRVLTAIEMGMKNHELVPGPLAAAIANLK-SGGVHKLLKELCKHKLLAYERGKKYDGYRLTNTGYDYLALKSLTLR .|||.|||||||||.||||.|||.|| | . |..|. ||.|..|..||||||......|||||||||. |||||||.... | MRYLSKEDFRVLTAVEMGMRNHEWVPTELIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR |
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| Kinase | CG11859.AA | APH | 200-247 | 20 | 2e-06 | 22.48 | Pfam | 150-199 (248) | Show / Hide |
Range on Protein: 200-247 Range on HMM: 150-199/248 Sequence Identity: 20% (11 aa) HELLDAPQ-VYDDLMNLIVRLGNSGVIHGDFNEFNLMVT--DAGKPI--LIDF ...... | ....| .. ...||||. |.|.. . | .. .||. DRQWWLWQRLWAWLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDW |
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| Kinase | CG11859.AA | APH | 120-181 | 20 | 0.0757 | 7.18 | Pfam | 1-63 (248) | Show / Hide |
Range on Protein: 120-181 Range on HMM: 1-63/248 Sequence Identity: 20% (14 aa) ICLKLH--RLGRTCFRNVKAKR-DYHGRRHKASWLYLSRISATREFAYMSALYDRGF--PVPKPIDF . .. . .||..| . | .| ||. .. .. .. ||.. . .| ..|. |||..... WWRPISGGWSNRTYYRTTDD-RPRYVLRRYPPP---WWAEELHREHRWLRHLAAHGIPVPVPRVLWG |
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