Gene CG3008 (Fruit Fly)
CG3008
Sequence
Protein domains of CG3008.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | CG3008.AA | RIO1 | 289-499 | 39 | 9.3e-113 | 352.11 | Pfam | 1-200 (200) | Show / Hide |
Range on Protein: 289-499 Range on HMM: 1-200/200 Sequence Identity: 39% (87 aa) VILHANSDANYTGSNEHGHQSGVLVPPQLLPRECAIKIFKTTLNEFKQRDRYIKDDYRFKDRFSKQNHRVIINMWAEKEMHNLMRMQAIGLNVPDVVVLK .. || | . .... |||.||..|....||...||...|.||..|....|.|....||||||..||.||...|...| .. .. NVYHAYS----MEDGKD---------------ECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWN KHVLVMRFIG-DNHNAAPKLKDAR----LSDAELSCAYEEIVA-AMHKLYNEAKLVHADMSEYNILWFEG-KCWFIDVAQSVEPKHPSALEFLMRDCGNI .|||||.||| ... .||.|||. ||. |... |.||. |...|.|..|||.|.||||||.... |.|.||..|.||. || |||||.|||.|| RHVLVMEFIGDKDGWPAPRLKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNI VNFFERRGLPN-IYTKEQL .|||.|.| .. ... ... INFFRRKGVDERVMDFREI |
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RIO | CG3008.AA | RIO | 247-505 | 41 | 2.6e-104 | 353.77 | SMART | 1-253 (253) | Show / Hide |
Range on Protein: 247-505 Range on HMM: 1-253/253 Sequence Identity: 41% (112 aa) KHEKVATAEMGLDAGTRLLLYKLINNQILEQIN--GIISTGKEAVILHANSDANYTGSNEHGHQSGVLVPPQLLPRECAIKIFKTTLNEFKQRDRYIKDD |. ||.| .| ||..|||..|. ..| || |.|||||||.. || . . ..|||.||..|...||| ..|||..| DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGG-----------------DFDKNGNECAVKIYRTSTTEFKRMWRYIQGD YRFKDRFSKQNHRVIINMWAEKEMHNLMRMQAIGLNVPDVVVLKKHVLVMRFIGDNHNAAPKLKDARLSDAELS---CAYEEIVAAMHKLYNEAKLVHAD |||..... | |... .|||||..||.||.. |...| .. ...||||| ||||. .||.|||. . ..| .|. |. |.|.|.|..||||| FRFKHGYHHINWRKMVRLWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHAD MSEYNILWF------EGKCWFIDVAQSVEPKHPSALEFLMRDCGNIVNFFERRGLPNIYTKEQLFEFITG .||||.|. ..| |.||..||||. || .|||| ||. || |||.|.| .. . ...||.||| LSEYNMLYHDLEDENDCKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG |
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Kinase | CG3008.AA | RIO3 | 252-514 | 53 | 5.6e-100 | 338.0 | In-house | 2-254 (254) | Show / Hide |
Range on Protein: 252-514 Range on HMM: 2-254/254 Sequence Identity: 53% (140 aa) ATAEMGLDAGTRLLLYKLINNQILEQINGIISTGKEAVILHANSDANYTGSNEHGHQSGVLVPPQLLPRECAIKIFKTTLNEFKQRDRYIKDDYRFKDRF .||| .| ||||.||..| .|| | | |.||||.|..|| | || | .. ...| .||||.|||||||||.||.|||||.|||||| STAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHA-----YGGSMEDEKEDS-----KVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRF SKQNHRVIINMWAEKEMHNLMRMQAIGLNVPDVVVLKKHVLVMRFIGDNHNAAPKLKDARLSDAELSCAYEEIVAAMHKLYNEAKLVHADMSEYNILWFE || | | | |||||||||| ||| |. .| ||.||||.||| ||| . |||||. .| |. || . . | .|| | |||||.||||.|| SKLNPRKIHRMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHA GKCWFIDVAQSVEPKHPSALEFLMRDCGNIVNFFERRGLPNIYTKEQLFEFITGLNSEVHTAA || |.|||.||||| || ||||.||| |. ||.. |. . .. .||. ..||| | GKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEA |
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Kinase | CG3008.AA | RIO | 254-513 | 30 | 4.4e-90 | 305.58 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 254-513 Range on HMM: 1-276/276 Sequence Identity: 30% (89 aa) AEMGLDAGTRLLLYKLINNQILEQINGIISTGKEAVILHANSDANYTGSNEHGH----QSGVLVPPQLLPRECAIKIFKTTLNEFKQRDRYIKDDYRFKD .| .| ||...||..| ...| ... |..|||..| |. ||| | | | .| ||||||..|....|| |..|......||. YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHC--------SNENGEDEKEDSKV------IPTECAIKIHRTGRTSFKDRKKYRDGEFYFKH RFSKQNHRVIINMWAEKEMHNLMRMQAIGLNVPDVVVLKKHVLVMRFIGDNHNAAPKLKDARLS-DAELSCAYEEIVAAMHKLYNEAKLVHADMSEYNIL |..| | | .. .||||||.|. |.. | .| .. .|.||||| ||. . .|||....... . . .| . .. | .||... |||.| .|.|.. RHCKHNWRYMHRLWAEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMM WFEGKC-------WFIDVAQSVEPKHPSALEFLMRDCGNIVNFFERRGLPNIYTKEQLFEFI------------------TGLNSEVHTA | .|| . ||. |.||..|| ||... ||| .. ||..|. . . .|.| .... .. WHDGKHDENDCGFYMIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM |
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Kinase | CG3008.AA | RIO1 | 321-499 | 40 | 9.3e-56 | 191.01 | In-house | 47-225 (225) | Show / Hide |
Range on Protein: 321-499 Range on HMM: 47-225/225 Sequence Identity: 40% (72 aa) ECAIKIFKTTLNEFKQRDRYIKDDYRFKDRFSKQNHRVIINMWAEKEMHNLMRMQAIGLNVPDVVVLKKHVLVMRFIGDNHNAAPKLKDARLSDAELS-C | ||||.|| || |..|. .|| .| | | | .|||||| || |. | ...| .||.| ||| . |||.|||. ... . EYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRIYQSEIPCPEPIMVKSNVLMMEFIGKDGMAAPRLKDYQYKERDQYFH AYEEIVAAMHKLYNEAKLVHADMSEYNILWFEGKCWFIDVAQSVEPKHPSALEFLMRDCGNIVNFFERRGLPNIYTKEQL | ... | .| . |||||.||||.| ...| ||| ||||. || .|||| .|| |. .|.... |.. . YYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHDHPHSLEFLRMDCKNVNMYFMKHNV-IIFPVRDI |
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Kinase | CG3008.AA | RIO1 | 258-293 | 47 | 3.7e-08 | 24.45 | In-house | 3-38 (225) | Show / Hide |
Range on Protein: 258-293 Range on HMM: 3-38/225 Sequence Identity: 47% (17 aa) LDAGTRLLLYKLINNQILEQINGIISTGKEAVILHA .| ||..|.|.. |. ||| ||||||. || IDPRTRMILFKMLTRGIITEINGCISTGKETNVYHA |