Gene PKCdelta (Fruit Fly)
PKCdelta
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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PKCdelta.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 259 | Kinase domain by global Sugen HMM | Fasta, JSON |
PKCdelta.AA | Protein | Various | 515 | None | Fasta, JSON |
PKCdelta.NA | RNA | None | 1548 | None | Fasta, JSON |
Protein domains of PKCdelta.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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C1_1 | PKCdelta.AA | C1_1 | 17-69 | 40 | 1e-18 | 72.38 | Pfam | 1-55 (55) | Show / Hide |
Range on Protein: 17-69 Range on HMM: 1-55/55 Sequence Identity: 40% (22 aa) HRFVAK-FFRQPTFCAFCNLFLWG-FGKQGYQCIICQTVVHKKCHDKLLGKCSGS |..|.. .|.|||||. |. |.|| .|.||..| |. ..|..|| |. .| .. HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN |
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C1 | PKCdelta.AA | C1 | 17-66 | 35 | 7.9e-16 | 59.82 | SMART | 1-61 (61) | Show / Hide |
Range on Protein: 17-66 Range on HMM: 1-61/61 Sequence Identity: 35% (22 aa) HRFVAKFFRQPTFCAFCNLFLWGFGKQ-----GYQCIICQTVVHKKCHDKLLG-------KC |..... | .||.|. |. ..||. || ||.|. |. ..|||||||.. | HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC |
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C1_1 | PKCdelta.AA | C1_1 | 89-141 | 41 | 9.8e-21 | 79.77 | Pfam | 1-55 (55) | Show / Hide |
Range on Protein: 89-141 Range on HMM: 1-55/55 Sequence Identity: 41% (23 aa) HRFKPH-TFMSPTFCDHCGSLM-GGFFIQGLKCEECDVNCHKKCERLTANLCGVN |....| .| .||||.|||... |... ||.||..| .|||..| .. ...|| | HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN |
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C1 | PKCdelta.AA | C1 | 89-138 | 30 | 8.6e-18 | 66.35 | SMART | 1-61 (61) | Show / Hide |
Range on Protein: 89-138 Range on HMM: 1-61/61 Sequence Identity: 30% (19 aa) HRFKPHTFMSPTFCDHCGSLMGGFF-----IQGLKCEECDVNCHKKCERLTAN-------LC |... ..| .||.|.||.....|.| .||..|..|...||||| . .. | HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC |
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Kinase | PKCdelta.AA | PKC | 187-445 | 61 | 1.4e-200 | 656.06 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-262/262 Sequence Identity: 61% (162 aa) FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEE |.|| ||||||||||.|||...|..|||||.|||||...||||..|..|..||||..|||.|.||.|.|||...|||||||.||||||||||...||.|| FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE RARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPF .||||.||||..|.|||.||||||||||||||||.|||..|||||||| ... ..|...|||||||.||||.....|...||||.||||.|||..||||| HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF SGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSP---AGDIADHIFF .|.||||||.||... |..|...| ||..|.||...|...||.|..... ..|| .| || HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF |
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Kinase | PKCdelta.AA | Delta | 187-445 | 72 | 6.1e-186 | 624.01 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-259/259 Sequence Identity: 72% (189 aa) FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEE |||..||||||||||.||||.....||||||||||||||||||..|..||.||||...||.||||||||||..|||||||||||||||.|||...||.|. FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK RARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPF |||||..|||.||.||||||||||||||||||||..||..|||||||| ..|..|.|..|||||||.|||||||.|||..|||||||||.|||||||||| RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF SGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF .|.|||||||||||..||.|..|..||...||.|.|.|..||.|.||.|.|||..|.|| HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF |
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Kinase | PKCdelta.AA | AGC | 187-445 | 31 | 1e-173 | 453.65 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-395/395 Sequence Identity: 31% (125 aa) FHFLAVLGKGSFGKVLLAELR------DTTYYYAIKCLKKDV-VLEDD--DVDSTLIE------------RKVLALGTK---------HPYLCH-LFCTF |.|| |.|||||||| |.. . || |||.|.|||.. ..... .|. |..| |..|.. . ||.... |...| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QTESH--LFFVMEYLN---------GG-DLMFHIQ---ESGRFSEERARFYGAE-------IISGLKFLHK-KGIIYRD-LKLDNVLLDYEGHVRIADFG |...| |.|||||.. || .|..|.| .|||.||||||| || |...| .||. .|||.|| ||..|.||| .||....||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG MCKLQIYLD--------------------------------------------------KTADSFCG--TPDYMAPEIIKGEKYNQNVDWWS--FGVLLY .|| . . ... .||| ||.||||||. |.. .|||| .|.|.| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EMLIGQSPFSGC----------DEDELFWSIC------NEIPWFP----------VYISAEATGILKGLLEKDYTKRIGSQYSP-----AGDIADHIFF |||.|..||.| ...|.| .|. |. . || ...| || ..|.||.|| .||.|.. . | .| .| .| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | PKCdelta.AA | Alpha | 187-445 | 59 | 6.7e-139 | 467.74 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-259/259 Sequence Identity: 59% (153 aa) FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEE | || ||||||||||.||| . | |||| |||||. ||||. |..|..||||. | |.| . .||| |.||||| ||||||.||| |.| | FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP RARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPF | || ||| || |||.|||||||||||||.|| |||..|||||||| .. |.| |||||||.||||| . | ||||.||||||||. || || HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF SGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF | |||||| .| . . .| .| || | ||.| | || |. . || | || DGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF |
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Kinase | PKCdelta.AA | Eta | 187-445 | 55 | 3.2e-132 | 445.56 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-261/261 Sequence Identity: 55% (144 aa) FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEE |.|. ||||||||||.|||...| |||| |||||.. ||||. |. |...|.| |||.| |.|.|||. ||||||| |||||||.|| . .| | FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP RARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPF ||||| ||... |.|||..|.|||||||||.||| ||| ..||||||| | ..| |||||||.||||.. .| |||| .|||.|||. ||.|| RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF SGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGD--IADHIFF ||.|| || .. .||... ||..|||. . | .||.|. . |. | | || EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF |
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Kinase | PKCdelta.AA | Akt | 187-445 | 46 | 2.6e-119 | 383.05 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-264/264 Sequence Identity: 46% (122 aa) FHFLAVLGKGSFGKVLLAELRDTTYYY-AIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSE | || ||||||||||.|.. || .| |.| ||||. .. . | |. ||..| ..||.. | |||. .|.|||.| |||.| .|.| .|||| FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQ-HCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE ERARFYGAEIISGLKFLHKKGIIYRD-LKLDNVLLDYEGHVRIADFGMCKLQ-IYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWS-FGVLLYEMLIG .|||||.||||... .||.|.||||| ||. |.|.|..||....|||.|| | . ....||||| |.||||..| . . ||||. .|...|||. | DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG QSPFSGCDEDELFWSICNEIPWFP--VYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF . || | ...| | |. || .|| |. ...|||.||..|| |. .. | .| .| .| RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | PKCdelta.AA | SGK | 187-445 | 38 | 6e-113 | 350.23 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-283/283 Sequence Identity: 38% (109 aa) FHFLAVLGKGSFGKVLLAELRDT------------------TYYYAIKCLKKDVVL-------EDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHL |.|| |.||||||||.... |. ||.| |.|. .. . ...||.|. ||| . | |||. | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL FFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGE .|||.|.|||.. .|.| ..|.| ||||| |||.. | ||.. ||||||| .|.||| .||... ||| ||..| .| .||||| |.|||..... YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ KYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF . ||||. | .||||..| || . ... | |. .| ..|..| ...|||.|| .|| |. ...| .|.|| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF |
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Kinase | PKCdelta.AA | PKN | 187-445 | 50 | 8.49999999999e-106 | 357.79 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-260/260 Sequence Identity: 50% (131 aa) FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALG--TKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFS |...||||.| ||||||.... | ||||| ||| .. |.|.| ..|..... ..||.| || ||||.| .|||||. ||||| || | || FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHED-VFS EERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQI-YLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQ | ||.|| | .. ||..||.. ||||||||||.||| ||.|.|||||.|| . | |.|. |||||...|||.. . | |||| |||.||||.| EPRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTS-TFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGE SPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF .||.| ||.|.| .| |. .| ..|.|| |.. || | .|.|. | || . || CPFPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQPFF |
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Kinase | PKCdelta.AA | Iota | 187-445 | 47 | 7.69999999999e-103 | 343.43 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-271/271 Sequence Identity: 47% (129 aa) FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEE |. . |.|.||. |||..|.. | ||.| .||..| .|.|.| |..| ||.| | ||||| ||||.|. ||||||||.| . || FELIRVIGRGSYAKVLMVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLPEE RARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPF |||| |||. |.|||..||||||||||||||| |||... |.|||| | | ||||| |.||||..|| |. |||| |||..||. | ||| HARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF SGCD---------EDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSP---AGDIADHIFF || || | | .| |...||| | || . |.| . || .| || DIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF |
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Kinase | PKCdelta.AA | RSK | 190-445 | 38 | 7e-102 | 344.78 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 190-445 Range on HMM: 1-278/278 Sequence Identity: 38% (107 aa) LAVLGKGSFGKVLLAELR---DTTYYYAIKCLKKDVVLEDD-DVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGR--- | |||.|..||| | || .|| | ||| .. . |. |. ||..|.. ..|| ...|. .||||..|. .|||..||.| |.|. .. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDY---EGHVRIADFGMCKL-QIYLDKTADSFCGTPDYMAPEIIK---GEK-YNQNVDWWSFGV |||..|.|| |||.. ...||..|||.||||..|.|.| |||... ||| ||. . . ...||.| .|||||..| ... .....||||.|| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV LLYEMLIGQSPFSG---CDEDELFWSICNEI--PWFP--VYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF |.|||| |..|| | . .|.. |.. . .| |.|.|| .....|..| ||.|. . | .| .| .| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | PKCdelta.AA | S_TKc | 187-445 | 35 | 2e-96 | 327.6 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-231/231 Sequence Identity: 35% (96 aa) FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNG--GDLMFHIQESGR-- ...| ..|||.|||| .. ..| ..|||..| .... |...| .||....|. .||. .||..||||..| |||. .|.. || YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG ----FSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQ-NVDWWSFGVLLY |.| .|||| ..|...|...|..|||.|||| .|.||| |. |.|||.... ..|||||.|||||.. .|. .||||.|..|| LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY EMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPA--GDIADHIFF ||| |. ||. .....| |. | || .....|.|| .||.. . ||. | .| EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | PKCdelta.AA | Pkinase | 187-445 | 32 | 4.3e-85 | 293.81 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-293/293 Sequence Identity: 32% (97 aa) FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTL-IERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGG----DLMFHIQ--E .|.. ..|.||||.| .. ..| .|.|..||. .. |. .. | .... .||. . |...|....|. .||||..|| ||. .|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR SGRF--SEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHV----RIADFGMCKLQ-IYLDKTADSFCGTPDYMAPEIIK-GEKYNQNVDWWS .|.| ||. ..|| .|..||...|..|||.||||..|.|.| .||. .|.||| .|. . . ...|||||.|||||.|. |..| . ||.|| HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS FGVLLYEMLIGQSPFSGC----DEDELFWSICNEIP-------WFPVYIS-----------------AEATGILKGLLEKDYTKRIGSQYSPAGDIADHI .|..||||| |. ||.|. . .. . ||. . . . || |. ..|..|.|| .||.. | .| | CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHP FF .| WF |
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Kinase | PKCdelta.AA | S_TK_X | 446-509 | 41 | 7.5e-24 | 86.48 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 446-509 Range on HMM: 1-79/79 Sequence Identity: 41% (33 aa) RPIDWGLLEK--RQIEPPFKPQVK----HPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQ---------FHGFTYTN | ||| |.. ..|||||||..| .| || .|| ||.| ..|||.|. ...||.|.. | |||| . RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | PKCdelta.AA | Pkinase_C | 465-511 | 51 | 8.9e-20 | 72.8 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 465-511 Range on HMM: 1-46/46 Sequence Identity: 51% (24 aa) QVKHPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQFHGFTYTNPH |||.|.||..|| ||.|....|| |.. . |.|| .|.||||.|| QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD |
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Kinase | PKCdelta.AA | TyrKc | 187-445 | 24 | 7.6e-15 | 17.3 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 187-445 Range on HMM: 1-280/280 Sequence Identity: 24% (73 aa) FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALG-TKHPYLCHLF--CTFQTE-----SHLFFVMEYLNGGDLMFHIQ ... .|| | ||.| ..... . |.|.||.| . . | ... .|| . |. || | . |. |||| .||| ... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR ESGR-FSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLD----KTADSFC-----GTPD-----YMAPEIIKGEKY .... .. . . | .| .||.|..| ||| |.|.. ...|.|.|||... || | | |. . |||| |. |. KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRD-IYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF NQNVDWWSFGVLLYEML-IGQSPFSG-----CDEDELFWSICNE-IPWFPVY--------ISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF . | |||||...|.. ||.| .| .. .|.. . . . | . ..| | | . | .| . | .| TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-------HECF |
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Kinase | PKCdelta.AA | Pkinase_Tyr | 353-398 | 39 | 5.8e-07 | 24.21 | Pfam | 181-228 (270) | Show / Hide |
Range on Protein: 353-398 Range on HMM: 181-228/270 Sequence Identity: 39% (19 aa) MAPEIIKGEKYNQNVDWWSFGVLLYEMLI-GQSP-FSGCDEDELFWSI |||| |. |.. | ||||||..|.. |..| . |.. |.. | MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI |
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Kinase | PKCdelta.AA | Pkinase_Tyr | 253-335 | 29 | 9.4e-07 | 23.5 | Pfam | 73-160 (270) | Show / Hide |
Range on Protein: 253-335 Range on HMM: 73-160/270 Sequence Identity: 29% (26 aa) CTFQTES-HLFFVMEYLNGGDLMFHIQE----SGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKL || | |. ... |||| .||| . .. .... .. . ..| .|. .|. |..| ||| |.|.. ...|.|.|||.... CTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD |
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Kinase | PKCdelta.AA | Pkinase_Tyr | 187-221 | 30 | 4.4e-05 | 17.85 | Pfam | 1-39 (270) | Show / Hide |
Range on Protein: 187-221 Range on HMM: 1-39/270 Sequence Identity: 30% (12 aa) FHFLAVLGKGSFGKVLLAELR----DTTYYYAIKCLKKD .|. .||.|.||.| ..... .|.. |.|.|| . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG |