Gene inaC (Fruit Fly)

inaC

Species: Fruit Fly
Alias: PKC 53E, ePKC, eye-PKC, PKC, Protein-kinase-2, dPKC53E(ey), Dpkc2, InaC, Pkc2: Protein-kinase-2, eye-specific PKC, pkc-2, eye PKC, Protein kinase-c2, dPKC53E, protein kinase C, PKC-eye, inaC, CG6518, SFO029
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 53E4,

Classification

Group: AGC
Family: PKC
Subfamily: PKCa

Sequence

Name Sequence Type Origin Length Description Download
inaC.AA Protein Various 700 None Fasta, JSON
inaC.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 259 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of inaC.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C1_1 inaC.AA C1_1 72-124 38 7.1e-21 80.29 Pfam 1-55 (55) Show / Hide 
Range on Protein: 72-124
Range on HMM: 1-55/55
Sequence Identity: 38% (21 aa)

HRFGVR-FFKNPTYCGHCKDFIWG-FGKQGFQCEECRFNIHQKCCKFVVFKCPGK
|.. .. .||.||.| ||..|.|| .|.||..|..| .|.|..|...|. .|...
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 inaC.AA C1 72-121 33 3.2e-16 61.13 SMART 1-61 (61) Show / Hide 
Range on Protein: 72-121
Range on HMM: 1-61/61
Sequence Identity: 33% (21 aa)

HRFGVRFFKNPTYCGHCKDFIWGFGKQ-----GFQCEECRFNIHQKCCKFVVF-------KC
|..  . | .|||| ||...|||. ||     |..|..|....|.||...|          |
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_1 inaC.AA C1_1 137-189 43 2e-21 82.31 Pfam 1-55 (55) Show / Hide 
Range on Protein: 137-189
Range on HMM: 1-55/55
Sequence Identity: 43% (24 aa)

HGWIST-TYTTPTFCDECGLLLHG-VAHQGVKCENCNLNVHHACQETVPPMCGAD
| |. . ..  ||||. || ...|  .|||.||..|..|.|| |.. |||.|| .
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 inaC.AA C1 137-186 27 4.1e-16 60.77 SMART 1-61 (61) Show / Hide 
Range on Protein: 137-186
Range on HMM: 1-61/61
Sequence Identity: 27% (17 aa)

HGWISTTYTTPTFCDECGLLLHGVAHQ-----GVKCENCNLNVHHACQETVPP-------MC
| |. ... .||.|. |. .. |...|     |..|..|....|. |.. ||.       ||
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C2 inaC.AA C2 208-295 48 1.2e-36 127.46 Pfam 1-90 (90) Show / Hide 
Range on Protein: 208-295
Range on HMM: 1-90/90
Sequence Identity: 48% (44 aa)

LKVDIKEAANLIPMD--TNGFSDPYIAVQMHPDRSGRTKKKTKTIQKNLNPVFNETFTFE-LQPQDRDKRLLIEVWDWDRTSRNDFMGSFS
|.| ..|| || |||   ||.||||  |....|..  .|.|||.|...||||.||||||.   |.  . .| ..|||||| .|.||.| ..
LRVHVIEARNLPPMDWDKNGKSDPYVKVYLGGDPKDTQKYKTKVIKNTLNPVWNETFTFDVPPPDLQH-TLRFTVWDWDRFGRDDFIGQCC
C2 inaC.AA C2 207-310 27 7.5e-29 103.09 SMART 1-92 (92) Show / Hide 
Range on Protein: 207-310
Range on HMM: 1-92/92
Sequence Identity: 27% (34 aa)

NLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTKKKTKTIQKNL---NPVFNE---TFTFELQPQDRDKRLLIEVWDWDRTSRNDFMGSFSFS---
 |.| |.|| ||.        |||. |.           |||.....|   |||.||   ||.|...|    . | .||||.      ||.| ....   
TLTVHIIEARNLP--------DPYVKVY-----------KTKVVKNTLSGFNPVWNEWMETFYFDVHP----Q-LRFEVWDH------DFIGHCCIPPNN

-----------LEELQKEPVDGWY
           |.... .. . |.
PHWHQWDGCIHLSDIL-GYRH-WW
Kinase inaC.AA Alpha 371-629 66 1.1e-219 736.07 In-house 1-259 (259) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-259/259
Sequence Identity: 66% (171 aa)

FNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKES
|||..|.||||||||.||||.|||||||.|.|.||||||.||.|..|.||..|||.|.|||||.|||||||||||.|||||..|||||||.||.|.|||.
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP

VAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPF
.|.|||.|.||.||||||..||||||||||..||.|||.|..|||..||...|.||||||||||.|.||||..|.||....|||.|||||.|.||||.||
HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF

EGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFF
.|.||...|..|.......||..|.||.||...||||.||.|||.|....|.|..||||
DGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF
Kinase inaC.AA PKC 371-629 59 3.9e-194 634.86 In-house 1-262 (262) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-262/262
Sequence Identity: 59% (156 aa)

FNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKES
|||.||.||||||||.||||.||||.||.|||.||||||.||.| .|.||..|||....|||...|.||||||||||||||..|||||.|.||..||||.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

VAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPF
.|.|||.|...||.||||..||||||||||.||| |||.|..|||..||......||.||||||.|.||||..|..|. . |||.||||..|.||||.||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

EGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYA---RQEITTHPFF
.|.||...|..| ... ..|...|.||..|...|.||.|..|||.....   .|.|..||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase inaC.AA AGC 371-629 32 1.1e-177 464.18 In-house 1-395 (395) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-395/395
Sequence Identity: 32% (130 aa)

FNFVKVIGKGSFGKVLLAERR------GTDELYAVKVLRKDV-IIQTD--DMELPMNE------------KKILALSGR---------PPFLVS-MHSCF
|.|.||||||||||| |....      .|...||.|||.|.. |....  ..|  |.|            ..||..             ||.|. .|..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTMDR--LFFVMEYCK---------GG-DLMYHMQ---QYGRFKESVAIFYAVE-------VAIALFFLHE-RDIIYRD-LKLDNILLDGEGHVKLVDFG
|. |.  |.|||||..         || .|..|.|   ..||| |..| ||| |       .. || .||. ..||.|| ||..||||| .||.||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKEGVTER--------------------------------------------------QTTRTFCG--TPNYMAPEIVSYDPYSIAADWWS--FGVLLF
|.|||....                                                  ..| ||||  ||.||||||.    |. |.||||  .|.|..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFMAGQAPFEGD----------DETTVFRNIK------DKKAVFP----------KHFSVEAMDIITSFLTKKPNNRLGAGRYA-----RQEITTHPFF
|...|. || ||          ..  .| .|.       .|  ||          ..||.||.|.|. .|.| |..|||.|.        .||  ||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase inaC.AA Eta 371-629 56 5.5e-132 444.77 In-house 1-261 (261) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-261/261
Sequence Identity: 56% (148 aa)

FNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKES
|||.||.||||||||.||||.||||.||.|||.|||||| ||.|  | ||.||.|  . ||| ..|.|||| |||||||||  |||||...|.  .| |.
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

VAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPF
 | ||| || .|| |||....||||||||||||| ||| || |||. |||. . .|| |||||| |.||||.    |  . ||| .|||..| |.||.||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

EGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGR--YARQEITTHPFF
| | |  .|  | .   ..|   . ||. |. .|.|| |. |||.       ..|  ||||
EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase inaC.AA SGK 371-629 42 6.1e-122 378.51 In-house 1-283 (283) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-283/283
Sequence Identity: 42% (120 aa)

FNFVKVIGKGSFGKVLLAERRGT------------------DELYAVKVLRKDVII-------QTDDMELPMNEK-KILALSGRPPFLVSMHSCFQTMDR
| | |||||||||||..... ..                  | .||.|||.|. ||       .     . | |. .|| .  . ||.|. |  ||| . 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNM-KHPFIVNLHYAFQTKWK

LFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSY
|.|||.|  ||.. ||.|  ..|.|..| ||| |.. ||  ||. |||||||| .||||| .||..| ||||.|||. . .|| |||||| |.|||.   
LYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRK

DPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFF
 |.. . |||. | .|.|.| |  ||.  .  . . ||  ... .|. .|..| |.|.  |.| | .|||. | .. ||  ||||
QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFM-EIKNHPFF
Kinase inaC.AA Delta 371-629 49 4.3e-119 401.95 In-house 1-259 (259) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-259/259
Sequence Identity: 49% (128 aa)

FNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKES
|.| ||.||||||||.||| .|... ||.| |.|||... ||.|  | |...|||. . |||  .   ||| . |||||||  |||||||.|| .||.|.
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

VAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPF
 | ||| |. ..| |||...||||||||||.||| .||.|. |||..|| ..  ... |||||| |.||||.  . |. . ||||||||..| . ||.||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

EGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFF
.|.||  .|. |   .  .|.. . || |..   . ..|. |||  .  . .|  |.||
HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase inaC.AA Akt 371-629 46 7.79999999999e-115 368.54 In-house 1-264 (264) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-264/264
Sequence Identity: 46% (123 aa)

FNFVKVIGKGSFGKVLLAERRGTDELY-AVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKE
|.|.||.||||||||.|..   |...| | |||.||.||| .  |  . |..||      ||.|..|  ||| |.|.|||.||.||.| ||.|. .||.|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN-HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

SVAIFYAVEVAIALFFLHERDIIYRD-LKLDNILLDGEGHVKLVDFGLSKEG-VTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWS-FGVLLFEFMAG
. | ||. |.  |. .||...||||| ||. |||.| .||..| ||||.||. ... ..| |||||| |.|||| .   .. |.|||. .|....|.| |
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

QAPFEGDDETTVFRNIKDKKAVFP--KHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFF
. ||  .|  . | .|| ..  ||  . .| |. |.|.. |.| |..|||.|    |||  ||.|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase inaC.AA AktR 371-629 41 6.30000000001e-111 374.83 In-house 1-268 (268) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-268/268
Sequence Identity: 41% (110 aa)

FNFVKVIGKGSFGKVLLAERR-GTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKE
| . |..||| |||| |....  ....|| |...|  ||.   |.   .|..|..   . ||.| .| |||| . |||.||||.||.| .| .. ..|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

SVAIFYAVEVAIALFFLHER-DIIYRDLKLDNILLDGEGHVKLVDFGLSK-EGVT-ERQTTRTFCGTPNYMAPEIVSY-DPYSIAADWWSFGVLLFEFMA
..| ||.... .|| .||.. .||||||| .||||| .||||..|||||| ...  .......||||| |||||..   ...  ..|||.||....| ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GQAPFEGDDETTVFRNIKDKK-AVFPKH--FSVEAMDIIT-SFLTKKPNNRLGAGRYARQEITTHPFF
|. ||. .. .. | .|| |    ||..  || ...|.|.   | | ||.||| ..   .||  ||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase inaC.AA Iota 371-629 47 4.5e-105 350.99 In-house 1-271 (271) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-271/271
Sequence Identity: 47% (128 aa)

FNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKES
|. ..|||.||. |||..| . |. .||.||..|... . .|..    ||..       |||| .||||||  |||||.|. .|||||.|||.  .  | 
FELIRVIGRGSYAKVLMVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLPEE

VAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPF
 | ||. |...|| ||||| ||||||||||.||| |||.|| |.|. |||. .  || ||||||||.||||.  . |  . |||  |||.|| ||| .||
HARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF

E--G----DDETT---VFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYA---RQEITTHPFF
.  |     |. |   .|  | .|.   |.  || |  .. .|| | | .|||  . .    ..|. ||||
DIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF
Kinase inaC.AA RSK 374-629 39 5.4e-103 348.46 In-house 1-278 (278) Show / Hide 
Range on Protein: 374-629
Range on HMM: 1-278/278
Sequence Identity: 39% (110 aa)

VKVIGKGSFGKVLLAERR---GTDELYAVKVLRKDVIIQTD-DMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGR---
.|| |.|..||| |  .     |. .||.|||.| .|.|.. | .  | | .||..... ||.|. |  ||| . |. .||||.||.| .| |. ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDG---EGHVKLVDFGLSKEGVTE-RQTTRTFCGTPNYMAPEIVS---YDP-YSIAADWWSFGV
| |. | ||. |.. |. .||...||.||||..|||.|    |||.||.|||..|... .  | | |||.| .|||||..     .  .. |.||||.||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLFEFMAGQAPFEG---DDETTVFRNIKDKK--AVFP--KHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFF
|..|  .|. || |   ..   ....|. .|    .|  .  | || |.|.  |.. |..|||.|.   .||  ||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase inaC.AA S_TKc 371-629 35 2.3e-98 333.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-231/231
Sequence Identity: 35% (95 aa)

FNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKG--GDLMYHMQQYGR--
. ....||||.|||| ..  ..|....|.|...          |  ..| .||    . |..| .. .||. |.|..||||| |  |||. .....||  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSI-AADWWSFGVLLF
    | | .| ||. ... || ..|.. ||.|||| .|||||   |.|. ||||...        .||||||.|||||..   .|.  ..||||.|..|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYAR--QEITTHPFF
|...|. ||.  .. ..|..|.          | || |.|   |.| |..|..|    .  ..|  ||.|
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase inaC.AA Pkinase 371-629 30 3.2e-79 274.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 371-629
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

FNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDME---LPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGG----DLMYHMQ-
. ....||.||||.| .. ..|| ...|||...|. .    |..   |  .| .|..   . |. | .. .|.. |.. .||||| ||    ||. ... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-QYGRF--KESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHV----KLVDFGLSKEG-VTERQTTRTFCGTPNYMAPEIVS-YDPYSIAADW
 ..|.|   | ...||. ... .| ..|.. ||.||||..|||.| .||.    |. ||||.|       . . ||||||.|||||..  . .|. ..|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGVLLFEFMAGQAPFEGD------DETTVFRNIKDKKAVFPKHFS---------------------VEAMDIITSFLTKKPNNRLGAGRYARQEITTH
||.|..|.|.. |. || |.      |.  ....|....  |.   .                      |. |.|.. |.|.|. |..      ..|  |
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQH

PFF
|.|
PWF
Kinase inaC.AA S_TK_X 630-693 37 8e-27 96.35 SMART 1-79 (79) Show / Hide 
Range on Protein: 630-693
Range on HMM: 1-79/79
Sequence Identity: 37% (30 aa)

RNVDWDKAEA--CEMEPPIKPMIK----HRKDISNFDDAFTKEKTDLTPTDKLFMMNLDQND---------FIGFSFMN
|..|||| ..  .|.|||.|| ||    .  |.||||. ||.|. .|||.|.  ... .||.         |.||....
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase inaC.AA Pkinase_Tyr 371-572 26 1.5e-21 73.59 Pfam 1-218 (270) Show / Hide 
Range on Protein: 371-572
Range on HMM: 1-218/270
Sequence Identity: 26% (59 aa)

FNFVKVIGKGSFGKVLLAERR----GTDELYAVKVLRKDVIIQ---TDDMELPMNEKKILALSGRPPFLVSMHSCFQ-TMDR--LFFVMEYCKGGDLMYH
  | |..|.|.||.| ... .    .|.   |||.|. .   .    .|.   |.| ||.   |. | .|... .     .   .. ||||...|||  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF---MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

MQQY----GRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEG-VTERQ-TTRTFCGTP-NYMAPEIVSYDPYSIAADW
 ..     .... .  . .....| .. .|... .| |||   |.|.. ...||  ||||..    ..   ..|. .  |   ||||  .|  .... | 
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

WSFGVLLFEFMA-GQAP-FEG
||||||..| .  |. | ..|
WSFGVLMWEIFTYGEQPTYPG
Kinase inaC.AA TyrKc 371-623 23 7.3e-17 49.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 371-623
Range on HMM: 1-280/280
Sequence Identity: 23% (67 aa)

FNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSG-RPPFLVSMHSCFQTM-------DRLFFVMEYCKGGDLMYHMQ
  . |..| | ||.| ... .   .  |||.|..|       .|  |.| .|.   | . | .| .. .  .        . |. ||||...|||  . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QYGR-FKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTE-------RQTTRTF--CGTP----NYMAPEIVSYDPYS
 ... .. .  . ... .|    .||.. .| |||   |.|.. ...||  |||||...  .          . .   .|        ||||   |  ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

IAADWWSFGVLLFE-FMAGQAPFEG-----DDETTVFRNIKDK-KAVFPKH--------FSVEAMDIITSFLTKKPNNRLGAGRYARQEI
.. | |||||...| |  || | .|      . . |....|.      |..         . |  .|...    .|..|       ....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase inaC.AA Pkinase_C 649-695 42 3.7e-15 56.59 Pfam 1-46 (46) Show / Hide 
Range on Protein: 649-695
Range on HMM: 1-46/46
Sequence Identity: 42% (20 aa)

MIKHRKDISNFDDAFTKEKTDLTPTDKLFMMNLDQNDFIGFSFMNPE
 .|.. |.||||. ||.|.  .|| |.  |.. ||. |.||.. ||.
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD