Gene Pk61C (Fruit Fly)

Pk61C

Species: Fruit Fly
Alias: SFO079, dPDK-1, Phosphoinositide dependent kinas, dPDK1, Pk61C, DSTPK61, PDK1, serine/threonine protein kinase., Phosphoinositide dependent kinase 1, Dstpk61, CG1201, CG1210
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 61B1,

Classification

Group: AGC
Family: PDK1

Sequence

Name Sequence Type Origin Length Description Download
Pk61C.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 262 Kinase domain by global Sugen HMM Fasta, JSON
Pk61C.AA Protein Various 752 None Fasta, JSON

Protein domain

Protein domains of Pk61C.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Pk61C.AA PDK1 162-487 41 2.2e-200 620.22 In-house 1-307 (307) Show / Hide 
Range on Protein: 162-487
Range on HMM: 1-307/307
Sequence Identity: 41% (149 aa)

FIFGRYIGEGSYSIVYLAVDIHS----RREYAIKVCEKRLILRERKQDYIKREREVMHQMTN----VPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYIN
||||..|||||||.||||.....    ...||||.||||.|.||.|..|..||.|.|....|    .||.|.|..||||...||||..|...||.|.|..
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYMK

R--VGSFDVACTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSA---KVMTA---------------HERALATEHCSEQRRSNSDE
.  .||||..|.|.||||...|.||.|.....||||||||||||.|||..|.|||.|   |....               | ..                
KQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQQHNKGMD--------------

DDEDSDRLENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRYNRHRKASFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGS----
                                        .     ..|..||||||.|||||.|.....||..|.||||||.|||.||.|||||.    
----------------------------------------KPEEDKQTRCKSFVGTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDAT

-NDYVIFKEILDCAVDFPQG--FDKDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFF
 |.|..|..|..|..|||..  |...|.|||.|||..||.|||...||.|.|..|.|||||
NNEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTSCDECGGYQQIKAHPFF
Kinase Pk61C.AA AGC 162-487 23 5.3e-137 356.51 In-house 1-395 (395) Show / Hide 
Range on Protein: 162-487
Range on HMM: 1-395/395
Sequence Identity: 23% (108 aa)

FIFGRYIGEGSYSIVYLAVDIH------SRREYAIKVCEKRL-ILRER--KQDYIKRE------------REVMHQMTN---------VPGFVN-LSCTF
| | . ||.||.. |||. . .      . . ||.||..|.  |.. .  .......|            |... .. .          |  |. | ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDQRS--LYFVMTYAR---------KG-DMLPYIN---RVGSFDVACTRHYAAE-------LLLACEHMHR-RNVVHRD-LKPENILLDEDMHTLIADFG
||..   ||||| |.           | ... ..    . |.||  ..|.||||       ..|| |..|. ....||| ||||||||||| |  ..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

SAKV----------------------------MTAHERALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRY
..|.                            |.  . .                                                       ..... 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMD--T-N-----------------------------------------------------K-CNPNNW

NRHR--------------KASFVG--TAQYVSPEVLQNGPITPAADLWA--LGCIVYQMIAGLPPFRGSN----------DYVIFKEIL------DCAVD
.|..                .|.|  |..|..||.|     ..|.| |.  |||. |.|..|.|||.| |           . .|. |.       . | 
QRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVK

FP----------QGFDKDAEDLVRKLLRVDPRDRLGA-QDEFG--YYESIRAHPFF
||          . |...| ||..||| .||..|||. .. ||   .| |..||.|
FPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase Pk61C.AA S_TKc 162-487 26 3.8e-89 303.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 162-487
Range on HMM: 1-231/231
Sequence Identity: 26% (89 aa)

FIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARK--GDMLPYINRVGS--
. ..| ||.|... ||....... |..|||.            . |.||......  . |  |.|  .|||  .||.|| |.    ||.. || . |.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FDVACTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHERALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDRDS
    |.   .|.|......| |..|.....|||||||||||||  |  |.|||.|...                                          
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------------

EELDDGDDEQQQEEMDSPRHRQRRYNRHRKASFVGTAQYVSPEVLQNGPITP-AADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDFPQGFDKD
                               .|.||  |..||||   . .. ..| |..|||.| |..| |||.  .....|| |.          ...
------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPE

AEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFF
| |..||.|..||..|..| . . . . |..||.|
AKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Pk61C.AA RSK 168-487 25 1.6e-69 237.24 In-house 7-278 (278) Show / Hide 
Range on Protein: 168-487
Range on HMM: 7-278/278
Sequence Identity: 25% (89 aa)

IGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERK-QDYIKREREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVGS---FDVACT
.| |.....   ..  ....|| || .|. | .  | . . ..||...   .. |  |.|  .||..  || .| | | |...  . . ..   |.    
GGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEA

RHYAAELLLACEHMHRRNVVHRDLKPENILLDE---DMHTLIADFGSAKVMTAH-ERALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDRDSEELDDG
. |.||. || ||.| . ..||||||||||.|.   . |  . ||| .| . .. .  . |                                       
CFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT---------------------------------------

DDEQQQEEMDSPRHRQRRYNRHRKASFVGTAQYVSPEVLQ----NGPITPAADLWALGCIVYQMIAGLPPFRG---SNDYVIFKEILDCA--VDFP--QG
                          |..|..|. ||.|     .|  . |.|.| ||.. | | .| |||.|   .|  .|.| |. .   ...|  | 
--------------------------FCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQY

FDKDAEDLVRKLLRVDPRDRLG-----AQDEFGYYESIRAHPFF
  ..| ||.||.| .|| .|||     |..       |..||.|
LSQEAKDLIRKMLHRDPHKRLGCGPQDAEE-------IKQHPWF
Kinase Pk61C.AA CAMK 167-487 18 6.9e-69 220.87 In-house 1-425 (425) Show / Hide 
Range on Protein: 167-487
Range on HMM: 1-425/425
Sequence Identity: 18% (90 aa)

YIGEGSYSIVYLAVDIHSR------------REYAIKVCEKRLIL-------------------------RERKQDYIKREREVMHQM------TNVPGF
 .|.||...|.|......             ...|||. .|. .                          |..... ..|| |.| ..       . |  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNLSCTFQD-------------------QRSLYFVM---TYARKG----DMLPYINRVGS---------------FDVACTRHYAAELLLACEHMHRRNV
..|  ...|                   .. .|.||    |.  |    |.. || . |.               |. . .|.|   .. | ...| .|.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENILLDEDM-----------------HTLIADFGSAKVMTAHER--------------ALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDR
|||||||||||||...                    |.||| |....  |               .                                  
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQW---------------------------------

DSEELDDGDDEQQQEEMDSPRHRQRRYNRHRKAS--------FVGTAQYVS-PEVLQN--------------GPITPAADLWALGCIVYQMIAGLPPFRG
                                 .        |.||  |.. ||||.                ...|..| |..|.| | |  | |||.|
-------------------------------TTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYG

S-------------NDYVIFKEILDCAVDFPQGFDKD------------------------AEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFF
.             ||| .|. |. .  |||  . ..                        . ||.||.|.||| .|. ...       . .||..
DCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQ-------CLNHPWM
Kinase Pk61C.AA MAST 162-487 25 6.5e-65 196.99 In-house 1-337 (337) Show / Hide 
Range on Protein: 162-487
Range on HMM: 1-337/337
Sequence Identity: 25% (94 aa)

FIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMHQMTNVPGFVNLSCTFQD--QRSLYFVMTYARKGDMLPYINRVG-SF
| | . |. | |  |||.  . .. ..|.||  .. ...   .| .. || .  . .| |  |.. ..||    . |..|| |   ||    .. .| ..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQN-PFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCM

DVACTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKV-----MTAHERA-----LATEHCSEQRRSNSDEDDEDSDRLENEDEDF
..  ...| ||. |. |  |    |||||||.|.|.| . |  ..||| .||      | |.       .  .                    .  .|. 
PEWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGK--------------------NHFNEYH

YDRDSEELD-----------DGDDEQQQEEMDSPRHRQRRYNRHRKASFVGTAQYVSPEVLQNGP-ITPAADLWALGCIVYQMIAGLPPFRGSNDYV-IF
.... ....           .  ..||..        .|  | |.. . .|| .| .|||.   .   ...| |..| |.|  ..|.||| |..    ||
IQKNYQQFQQDFGINGNTNKNQIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIF

KEILD--CAVDFPQG--------FDKDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFF
  |.     . .| .        . ..| ||..|||...|..||||.   | .| |  ||||
QNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN---GADE-IKQHPFF
Kinase Pk61C.AA AktR 162-487 26 1e-63 218.02 In-house 1-268 (268) Show / Hide 
Range on Protein: 162-487
Range on HMM: 1-268/268
Sequence Identity: 26% (91 aa)

FIFGRYIGEGSYSIVYLAVDI-HSRREYAIKVCEKRLILRERKQDYIKREREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDV
| . . .|.| .. |||. .   . . ||.|.  |  | ........ .|| .|  . | |..|.|  .||... |.|.| | . |... .... . |. 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ACTRHYAAELLLACEHMHRR-NVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHERALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDRDSEELDDG
  .| |.|. ||| |. | . |.. ||||||||||||| |  |.||| .|                                                  
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK--------------------------------------------------

DDEQQQEEMDSPRHRQRRY-NRHRKASFVGTAQYVSPEVLQN-GPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCA-VDFPQG--FDKDAE
               |    .. .  ||.|| .|..||....  . . ..|.||.|. .| |..|.|||  .|.  .|. |. .  . ||.   | . . 
--------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCK

DLVR-KLLRVDPRDRLG-----AQDEFGYYESIRAHPFF
||.  |||  .|. |||     ...       |. ||.|
DLIQRKLLCKNPNKRLGYYCNGWEE-------IKSHPWF
Kinase Pk61C.AA Ciliate-E2 162-487 18 1.5e-56 192.59 In-house 1-365 (365) Show / Hide 
Range on Protein: 162-487
Range on HMM: 1-365/365
Sequence Identity: 18% (84 aa)

FIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRL------------------ILRERKQDYIKREREVMH---------------QMTNVPGFVNLSC
..| . ||.|....||.. ..  ....|||. . ..                  |.....  .||.|  .|                .  | |  ...  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

TFQ--DQRSLYFVMTYARKGDMLPYIN------------RVGSFDVACTR---------------HYAAELLLACEHMHRRN-VVHRDLKPENILLDEDM
.||  |. ..|.|| |.  ||.. ||.              ..|.    .               .|.|...|| |..| .| ..|||.||||||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

HTLIADFGSAK-----------------------------VMTAHERALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDRDSEELDDGDDEQQQEEMD
   |.||| .|                              |      .                                                   
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD-----Q---------------------------------------------------

SPRHRQRRYNRHRKASFVGTAQYVSPEVLQNGP---------ITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDFP--------------
       .   .   ...||. |..||.|....          . ..|.|.||.| |.|. | |||        ...|..| .|||              
-------IIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCK

----QGFDKDAEDLVRK----LLRVDPRDRLGAQDEFGYYESIRAHPFF
    .  .... || .|    .| .||  |..       .| |  ||.|
WKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT------GWEQILNHPWF
Kinase Pk61C.AA SGK 162-309 34 1.3e-38 116.53 In-house 1-173 (283) Show / Hide 
Range on Protein: 162-309
Range on HMM: 1-173/283
Sequence Identity: 34% (59 aa)

FIFGRYIGEGSYSIVYLAVDIHS------------------RREYAIKVCEKRLIL-------RERKQDYIKREREVMHQMTNVPGFVNLSCTFQDQRSL
|.|   ||.||.  ||...                         ||.||  |  |.       .  .| .|. ||.|  .  . |  |||   || .  |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YFVMTYARKGDMLPYINRVGSFDVACTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAK
|||| |.  |.|  ...| ..|     | ||||. .| |. |  ....||||||||||| . |  . ||| .|
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCK
Kinase Pk61C.AA Pkinase 162-314 32 1.1e-37 134.33 Pfam 1-165 (293) Show / Hide 
Range on Protein: 162-314
Range on HMM: 1-165/293
Sequence Identity: 32% (54 aa)

FIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIK-REREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKG----DMLPYIN--R
. .|| ||.||.. ||..... .....|.|. .|| .  . .|  .. .| ..|. . | |  | | ..|.| ...|.|| |...|    |   ||   |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

VGSF--DVACTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHT----LIADFGSAKVM-TAH
 |.|  .    ..|. ..| . |..|.....||||||||||.|...|.     |.|||.||.. . .
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-N
Kinase Pk61C.AA PKA 162-312 37 1.8e-36 127.52 In-house 1-152 (263) Show / Hide 
Range on Protein: 162-312
Range on HMM: 1-152/263
Sequence Identity: 37% (57 aa)

FIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMHQMTNVPGFVN-LSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDV
| . . .| ||.  |.|. . || . ||.|.  |. | |.. .. .. |. .. .... |  |. .  |||| | ||.|| |. .|.|  |. ..|.|. 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKH-PFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN

ACTRHYAA-ELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMT
  .. ||| .  || | .|  | ..|||||||||.|.. |  |.||| || ..
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVD
Kinase Pk61C.AA PKC 162-309 35 1.3e-33 106.22 In-house 1-148 (262) Show / Hide 
Range on Protein: 162-309
Range on HMM: 1-148/262
Sequence Identity: 35% (53 aa)

FIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDVA
| | . .| ||.  | ||    ... |||||  | .|.     .    |. |. . .. |  ..| |.|| .  |.||| | . ||    | ... |...
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

CTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAK
 .| |||| ..|   .|..... |||| .|.|||.. |  ||||| .|
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCK
Kinase Pk61C.AA Pkinase 385-487 24 6.4e-30 106.87 Pfam 170-293 (293) Show / Hide 
Range on Protein: 385-487
Range on HMM: 170-293/293
Sequence Identity: 24% (32 aa)

SFVGTAQYVSPEVLQ-NGPITPAADLWALGCIVYQMIAGLPPFRGS------NDYVIFKEILDCAVDFPQGFD---------------------KDAEDL
.|.||  |..|||.. . ...|..| |..|||.|.|. | |||.|.      ........|... ..|.   .                     ... |.
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF

VRKLLRVDPRDRLGAQDEFGYYESIRAHPFF
....|..|| .|..        | |  ||.|
IKWCLCKDPKKRPT-------AEQILQHPWF
Kinase Pk61C.AA PKA 388-487 35 2e-28 100.78 In-house 160-263 (263) Show / Hide 
Range on Protein: 388-487
Range on HMM: 160-263/263
Sequence Identity: 35% (38 aa)

GTAQYVSPEVLQNG-PITPAADLWALGCIVYQMIAGLPPFRGS--NDYVIFKEILDCAVDFPQGFDKDA---EDLVRKLLRVDPRDRLGAQDEFGYYESI
|| .|  ||..|.  .   . | ||||...| | || |||. .  .   |.. |... ..||. ||.||    ||..||| ||.  |.| ...    ..|
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKN--GVNDI

RAHPFF
. |..|
KNHKWF
Kinase Pk61C.AA PKC 384-487 32 2.8e-27 85.35 In-house 158-262 (262) Show / Hide 
Range on Protein: 384-487
Range on HMM: 158-262/262
Sequence Identity: 32% (34 aa)

ASFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDFPQGFDKDAEDLVRKLLRVDPRDRLGAQDEF-GYYESIR
..| ||  |..||.||  . ... | ||.|   |.| || .|| | .   .|. |..  . .|  . |.| ..  ...  .| .|||.. .  .  . ||
STFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIR

AHPFF
.||||
EHPFF
Kinase Pk61C.AA SGK 385-487 39 1.5e-25 75.49 In-house 184-283 (283) Show / Hide 
Range on Protein: 385-487
Range on HMM: 184-283/283
Sequence Identity: 39% (41 aa)

SFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDFPQGFDKDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAH
.| ||  |  ||||.  |   . | | |||. | |. |||||   |    .  |.     .|...  || ||   ||  ||..|||. . |   . |. |
TFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDF---MEIKNH

PFF
|||
PFF
Kinase Pk61C.AA TyrKc 162-384 14 1.1e-08 -82.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 162-384
Range on HMM: 1-280/280
Sequence Identity: 14% (43 aa)

FIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMHQM-TNVPGFVNLSCTFQDQ-------RSLYFVMTYARKGDMLPYIN
  .|. .||| . .||... .   .. |.|.. .        .  . || ..|..   . |  |.|     .|         |. || |. .|| . |. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RVGS-FDVACTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAH-------ERALA----TEH-----------CSEQRRSN
. .  . ..   ...      .|. |..|..||||   |.|..|. .  |.||| ..  . .       .   .     ..           |   .. .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

SDED-------------DEDSDRLE-----NEDEDFYDRDSEELDDGDDEQQQEE---------------------MDSPRHRQRRYNRHRKA
.  |             . ..   .      .... . .    ...|.   | ..                     .  |  | .  . |.. 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEY----VKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
PDK1_PH Pk61C.AA PDK1_PH 579-678 57 1.1e-62 214.51 In-house 1-112 (112) Show / Hide 
Range on Protein: 579-678
Range on HMM: 1-112/112
Sequence Identity: 57% (64 aa)

DKWHVFA--DGEVILKKGFVNKRKGLFA----RKRMLLLTTGPRLIYIDPVQMIKKGEIPWS-PDLRAEYK-----NFKIFFVHTPNRTYYLDDPEGYAI
..|| |.  .||.||| | |.|||||||    ..|.|.||.||||.|.||..| .||||||| .||..|||     |||.||.||||||||. ||.|.|.
TPWHQFLMPEGEHILKCGWVYKRKGLFAKPKKKRRQLILTDGPRLFYVDPMTMVIKGEIPWSSKDLYVEYKPDRKNNFKHFFIHTPNRTYYFEDPKGCAN

HWSEAIENMRKL
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KWCEAIEKVCKR