Gene PDK (Fruit Fly)
PDK
Sequence
Protein domains of PDK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| BCDHK_Adom3 | PDK.AA | BCDHK_Adom3 | 31-194 | 36 | 4.9e-79 | 273.58 | Pfam | 1-199 (199) | Show / Hide |
Range on Protein: 31-194 Range on HMM: 1-199/199 Sequence Identity: 36% (73 aa) SPLSIKQFMDFGQ-NACEKK---SYIFLRKELPVRLANIMKEIALLPDNLLHTRSVSEVSSWYVKSFEDVLV-Y-------------EKAEPTHDN---- .|||..|.|.||. |.|||. |..|...|||.|||....|. .||..|... ....| .||..|||... . |....|... TPLSLRQMMQFGRPNPCEKTLFKSAQFCHEELPIRLAHRIRELQNLPYGLNKMPHIQQVYNWYYQSFEELRECFPKPISELKHLRYYEPPPKTLEDWLHD -LQKFVADLDLIRNRHN-DVVQTMAQGVIEMK-ENEGGQVDAPTES----SIQYFLDRLYMSRISI---RMLINQHTLLFG---GNPHA--GGRHIGCLD .||. | |..||. .||.||||||.|.| . . ..| ... .||||||| |||||.| ||||.||..||. |||. ...|. . YNEKFCDMLRDIKDRHDRNVVPTMAQGVLEWKCRYY--GQDNQPDDLHWFQIQYFLDRFYMSRIGINFIRMLIGQHIALFEFNYHNPHHFEHPDYVGIIC P . T |
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| Kinase | PDK.AA | PDHK | 242-368 | 63 | 1.8e-74 | 253.72 | In-house | 1-125 (125) | Show / Hide |
Range on Protein: 242-368 Range on HMM: 1-125/125 Sequence Identity: 63% (81 aa) YVPSHLYYMLFELFKNSMRAVVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQPSKSDLHTVPLAGYGYGLPISRLY ||||||| ||||||||.||| ||| |.| .||.|| . ||||. .|.||.|||.| . | || |||||||.|. .||||.||||||.||| YVPSHLYHMLFELFKNAMRATVEH--HENRKIYPPIKVMVTLGKEDLTIKMSDRGGGVPLRKIDRLFNYMYSTAPRPQMETSRAAPLAGFGYGLPICRLY ARYFHGDIVLLSCEGFGTDAIIYLKAL |.|| ||. | | ||.||||.|||||| AKYFQGDLKLYSMEGYGTDAVIYLKAL |
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| Kinase | PDK.AA | PDHK | 242-368 | 53 | 2.6e-71 | 243.25 | In-house | 1-140 (140) | Show / Hide |
Range on Protein: 242-368 Range on HMM: 1-140/140 Sequence Identity: 53% (76 aa) YVPSHLYYMLFELFKNSMRAVVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQ----PSK----------SDLHTVP |||.|||.||||||||.||| .||| | .|| || . |.|| .|.|| |||.| . | || ||||||| |. . .| YVPMHLYHMLFELFKNAMRATMEHH-EDRPYNYPPIKVMVALGDEDLTIKMSDRGGGVPHRKIDRLFNYMYSTAPRSTQDPRMSPLFGHLDMHETSRAAP LAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKAL ..|.||||||.||||.|| || | | ||.||||.|||||| MHGFGYGLPICRLYAKYFQGDLQLYSMEGYGTDAVIYLKAL |
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| Kinase | PDK.AA | HATPase_c | 242-368 | 20 | 4e-18 | 65.3 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 242-368 Range on HMM: 1-120/120 Sequence Identity: 20% (28 aa) YVPSHLYYMLFELFKNSMRAVVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPR------SQTDQLFKYMYSTAPQPSKSDLHTVPLAG--YGY .| .|. .. .| |.... | . ..| . . ...... ..| | ||| . ...| |.| |. . | |. GDPDRLHQVVWNLVDNAIKHTPEG---------GHITVRVHRDDDHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-----SR-RKYGGGLTGL GLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKAL || |.| ... ..|.| . | .| || ...|. GLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE |
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| Kinase | PDK.AA | HATPase_c | 242-369 | 20 | 3.2e-13 | 51.18 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 242-369 Range on HMM: 1-130/130 Sequence Identity: 20% (29 aa) YVPSHLYYMLFELFKNSMRAVVEHH----GHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPR------SQTDQLFKYMYSTAPQP--SKSDLHTVPLA | .|. .| .| .|. .. | | .|| ... ..| . .. ..| | ||| . ...| .|.|...| ...| .. GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYG G--YGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKALS | |.||.|.. ... ..|.| . | ...|. GGLTGLGLSICKRIVEQHGGTIWVE------TTFTFTLPLER |
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