Gene auxillin (Fruit Fly)

auxillin

Species: Fruit Fly
Alias: CG1107, auxillin, SFO128, GAK, Auxilin
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 82A1,

Classification

Group: Other
Family: NAK
Subfamily: GAK

Sequence

Name Sequence Type Origin Length Description Download
auxillin.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 271 Kinase domain by global Sugen HMM Fasta, JSON
auxillin.AA Protein Various 1165 None Fasta, JSON

Protein domain

Protein domains of auxillin.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase auxillin.AA GAK 50-319 64 5.4e-228 763.72 In-house 1-277 (277) Show / Hide 
Range on Protein: 50-319
Range on HMM: 1-277/277
Sequence Identity: 64% (180 aa)

LRIKCVIAEGGYAFVYVAQDVQTGTEYALKRLIGADMQASTAIINEINIHKQLSGHENIVAFVGSSYTAP--STQLGAQYLLLTELCKGGSLVDCFR--T
.|..|||||||.||||||||||||.||||||....||||..||||||...|.|.||||||.|...||...  |.|..|.||||.|.||...||||..  .
YRVRCVIAEGGFAFVYVAQDVQTGREYALKRMLSHDMQANRAIINEICMMKKLQGHENIVQFCDASYISREESNQSQAEYLLLMEYCKFSQLVDCLKRME

NNAPFNPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGSASTEVLSPTFEWSANQRSMLEDQLNTVTTPMYRSPEMLDTWSNN
...||...|||||||||.|||...|||.|||.|||||||||||||.|.|||||||||.|....|...|||..|||.||.....||||||||||.|..||.
CYKPFSCDCVLRIFYQMCRAVQHMHSQKPPIIHRDIKIENFLIGNQKTIKLCDFGSATTKSHYPDYSWSAQKRSMVEDEMFRHTTPMYRSPEMCDLYSNW

PIGPKVDIWALGCILYFLCYRKHPYEDGGKLRIINANYM--LPP-DPQYQCFSDIIRGCLKVNPFERLDITMVLEGL
|||.|.||||.||.|||.|||.||.|||.||||||.|||  .|| |.||.||.|.||.||.|||.|||||.||.|..
PIGHKQDIWAMGCMLYFMCYRQHPFEDGAKLRIINGNYMKPIPPQDNQYMCFHDLIRACLQVNPDERLDIAMVVEYM
Kinase auxillin.AA NAK 50-319 39 7.79999999999e-150 503.41 In-house 1-299 (299) Show / Hide 
Range on Protein: 50-319
Range on HMM: 1-299/299
Sequence Identity: 39% (118 aa)

LRIKCVIAEGGYAFVYVAQ---------DVQTGTEYALKRLIGA-DMQASTAIINEINIHKQLSGHENIVAFVGSSYTAPS-TQLGAQYLLLTELCKGGS
.......||||...||..|         ....|..|||||.|   |.|.  |...||...|.|..|.||| ...|... .. .. . ...|| |.|..||
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS

LVDCF--RT--NNAPFNPTCVLRIFYQMARAVASLHSQSP--PIAHRDIKIENFLIG---NDKQIKLCDFGSASTEVLSPTFEWSANQRSMLEDQLNTVT
|.| .  |.  .. .|.  ..|.||......|. .|.. |  ||.||||||||.|..   .|...|||||||..|....|. .|.|..|||..|. |. |
LWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINKYT

TPMYRSPEMLDTWSNNPIGPKVDIWALGCILYFLCYRKHPYED------GGKLRIINANYM--LPPD-PQYQCFSDIIRGCLKVNPFERLDITMVLEGL
|||||.|||.|..||.||. |||||||||.||..|...||.||      ..||.|.|.||.   |..  ..|.. |.||..|...| .|..| .||. |
TPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHPFEDCYQRHDSSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL
Kinase auxillin.AA NAK-Unclassified 50-321 22 2.2e-67 230.15 In-house 1-405 (405) Show / Hide 
Range on Protein: 50-321
Range on HMM: 1-405/405
Sequence Identity: 22% (92 aa)

LRIKCVIAEGGYAFVYVAQ--------D------VQTGTEYALKRLIGADMQASTAIINEINIHKQLSGHENIVAFVGSSYT-APSTQLGAQYLLLTELC
 .|   .|||| .|||...        |        ..  |.||| |  | .   .  .||.. | . .|.|||   ...   .   . .  ...| |.|
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQSYEVFMLMEYC

KGGSLVDCFR---------TNNAPFNPTCVLRIFYQMARAVASLHSQSP--------------------------------------------PIAHRDI
..|||.|            |    |    .|.|... ..... .|...|                                            |..||||
SRGSLQDFMNNQRTIYQRLTEQTRFHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHRDI

KIENFLIG----------------------------------------------------------NDKQIKLCDFGSASTEVLSPTFEWSANQRSMLED
|||| |.                                                           ..   |||||||....   ..    . ... |.|
KIENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIE---NRQEMQYLQD

QLNTVTTPMYRSPEMLDTWSNNPIGPKVDIWALGCILYFLCYRKHPYEDGGKLR-------IIN--ANYMLPPDPQY-QCFSDIIRGCLKVNPFERLDIT
  |. ||| ||.|||.|. .. ||  |.||||||| || .|.   | |..| |        |..  ..|  |. ..|   .   |. .| ..| .|. | 
WINMHTTPQYRAPEMIDLYRCCPIDEKIDIWALGCFLYKMCFYTTPFEMCGQLHNASVTYKILHGLGKYEFPSNHNYSNQLHNLIKIMLNEDPIQRPNIY

MVLEGLAA
 ||. .  
QVLNHICQ
Kinase auxillin.AA S_TKc 50-322 24 3.2e-61 210.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 50-322
Range on HMM: 1-231/231
Sequence Identity: 24% (69 aa)

LRIKCVIAEGGYAFVYVAQDVQTGTEYALKRLIGADMQASTAIINEINIHKQLSGHENIVAFVGSSYTAPSTQLGAQYLLLTELCKG--GSLVDCFRTNN
 .|  .| .|... || .... || ..|.|..          |..||.|.|.  .|.||| . .. ..         . . .|.| |  |.| |  . ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRG

AP-----FNPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGSASTEVLSPTFEWSANQRSMLEDQLNTVTTPMYRSPEMLDTW
 .     |..  . ...||...|.. .||.   | |||.| || |. .  .||.||||.|                         . || |..||.|   
RHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL-------------------TTFCGTPWYMAPEVL---

SNNPIGP-KVDIWALGCILYFLCYRKHPYEDGGKLRIINANYMLPPDPQYQCFSDIIRGCLKVNPFERLDITMVLE-G-----LAAL
   . |. |.|.|..||||| ..... |..     ....           . . |.||.||...| .|. .  .|. .        .
---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase auxillin.AA BIKE 50-291 34 4.3e-55 189.34 In-house 1-239 (267) Show / Hide 
Range on Protein: 50-291
Range on HMM: 1-239/267
Sequence Identity: 34% (85 aa)

LRIKCVIAEGGYAFVYVAQDVQTGTEYALKRLIGADMQASTAIINEINIHKQLSGHENIVAFVGSSYTAPSTQLGAQYLLLTELCKGGSLVDCF--RTNN
  .  ..||||.| |....| . |. .||||     ..   .   |. | ||.||| ||| .| .. .. . .     ..|.| |..  .|.    | . 
VTVEEQLAEGGFAMVFLVRD-HKGNKCALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIGNGV-WECMILMEYCRH-QVVNMMNQRLQQ

A-PFNPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDK--QIKLCDFGSASTEVLSPTFEWSANQRSMLEDQLNTVTTPMYRSPEMLDTWSN
   |    ||.||  .. ||. ||    || ||| |.|| |. . .     ||||||| . .|.|  . . |   . .|     ||  ||.||| | .| 
GQYFTEQEVLQIFCDVCEAVSRLHHCQTPIIHRDLKVENILLHDHGPPHYVLCDFGSATNKFLNPQKH-GVN---YVKDEIEKYTTMCYRAPEMIDLYSG

NPIGPKVDIWALGCILYFLCYRKHPYEDGGKLRIINANYMLPPDPQY
 .|. | |||||||.|| ||.   |..   .| | . |. .|  ..|
KEITTKADIWALGCMLYKLCFFCLPFGE-SQLAICDGNFTIPDNSKY
Kinase auxillin.AA CAMK 55-317 17 3.2e-46 146.52 In-house 1-421 (425) Show / Hide 
Range on Protein: 55-317
Range on HMM: 1-421/425
Sequence Identity: 17% (73 aa)

VIAEGGYAFVYVAQDVQTG------------TEYALKRLIGADMQAS----------------------------TAIINEINIHKQLSG------HENI
.. .|... |. ... .|.            ...| | .    .. .                              . .||.|.|.|.|      |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VAFVGSSYTAPSTQLGA--------------QYLLLT---ELCKGG----SLVDCFRTNNA--------------PFNPTCVLRIFYQMARAVASLHSQS
. .     ..  .  ..              .. . .   |.| ||     | |  . .                 |.   . |.| |.. ||. .||. 
IKLYEVYEDPHYFK-NTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

PPIAHRDIKIENFLIGNDK-----------------QIKLCDFGSA--STEVLSPTFEWSANQRSMLEDQ----------LNTVT-TPMYRS-PEMLDTW
  |.|||.| || |. ...                 .||..||| |   ..  . ... . .... . ..          ..|.  || | . ||.|   
--IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK

S-----------NNPIGPKVDIWALGCILYFLCYRKHPYEDG-----------------GKLRIINANYMLPPDPQY-----------------------
.           . ..|||.|.|..|.|||..   . |...                   . .|....|  ||..                         
GHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS

QCFSDIIRGCLKVNPFERLDITMVLE
|   | ||..|.|.| .|. |. .|.
QECKDLIRKMLQVDPEKRMTIEQCLN
Kinase auxillin.AA TKL 56-319 18 2.8e-39 136.81 In-house 1-364 (364) Show / Hide 
Range on Protein: 56-319
Range on HMM: 1-364/364
Sequence Identity: 18% (69 aa)

IAEGGYAFVYVAQDVQ--------TGTEYALKRLIG------------------------ADMQASTAIINEINIHKQLSG--HENIVAFVGSSYTAPST
| .||.. || ..  .        ||.. | |..                           |. || .   |..  ...|   |.||| |.|..   |..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

Q-------LGAQYLLLTELCKGGSLVDCFRTNNAPFNPTCVLRIFYQMARAVASLHSQS------PPIAHRDIKIENFLIGNDKQ--------------I
.          |. . .|.|.|||| . .        .   .|. ...||... |||.       |||.|||.| .| |. .. .              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLCDFGSAS-TEVLSPTFEWSANQR------SMLEDQLNTVTTPMYRSPEMLD---TWSN----------NPIGPKVDIWALGCILYFLCYRKHPYEDGG
|.|||| .   .  .    .. ...      .  .   . . || . .||.|.     ..           .  .|.|... | .|. .. |..||.| .
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

KLR-----------IINANYMLPPDPQ------------YQC---FSDIIRGCLKVNPFERLDITMVLEGL
              .....  |.| .              .|   .....  | . .| .|.  . .|. |
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase auxillin.AA Ciliate-E2 50-317 18 2e-35 119.06 In-house 1-361 (365) Show / Hide 
Range on Protein: 50-317
Range on HMM: 1-361/365
Sequence Identity: 18% (69 aa)

LRIKCVIAEGGYAFVYVAQDVQTGT-----------------------EYALKRLIGADMQASTA---IINEINIHK----------QLSGHENIVAFVG
  .  .| .|... || ... ...                        .||.|...  . ..      |..|||. .          ..  | ||. .. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMYE

SSYT-APSTQLGAQYLLLTELCKGGSLVD--CFRTNNAPFNPT--------CVLRIFYQMAR---------------AVASLHSQSPPIAHRDIKIENFL
. ..   ..     . | .|.|.||.| |    .  . .....         ...|..| ..               |. .|||. . | ||||| || |
CFQEKDDNN-----IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENIL

IGNDKQIKLCDFGSASTEVLSPTFEWSANQRS-MLEDQLN--------------------TVTTPMYRSPEMLDTWS------NNPIGPKVDIWALGCIL
.     ||..||| .     .   .   .|.. .. .  |                    .. ||.| .||.|   .       .. . |.|||.||.||
F-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

YFLCYRKHPYEDGGKLRIINA-NYMLP-----------------PDPQYQCFSDIIRG----CLKVNPFERLD-ITMVLE
|.... |.|.     ...|   .. .|                 ..   |   |.|.     .|...| .|.. .  .|.
YEMLFGKPPF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase auxillin.AA Pkinase 50-202 27 1.2e-31 113.03 Pfam 1-159 (293) Show / Hide 
Range on Protein: 50-202
Range on HMM: 1-159/293
Sequence Identity: 27% (47 aa)

LRIKCVIAEGGYAFVYVAQDVQTGTEYALKRLIGADMQASTAIIN----EINIHKQLSGHENIVAFVGSSYTAPSTQLGAQYLLLTELCKGG----SLVD
..|. .| .|... || .... || ..|.|..   .   .  ...    || |.| | .|.||| . .. ..      .  . . .|.| ||    .| |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFD

CFR-TNNAPF--NPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQI----KLCDFGSA
  .  .. .|   .  . ...||..|... .||.   | |||.| ||.|| |. .|    |.||||.|
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase auxillin.AA TKL-ciliate1 124-319 23 1.7e-30 101.58 In-house 67-279 (279) Show / Hide 
Range on Protein: 124-319
Range on HMM: 67-279/279
Sequence Identity: 23% (52 aa)

GAQY----LLLTELCKGGSLVD-CFRTNN--APFNPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGSASTEVLSPTFEWSAN
...|     . .|.| .|...| | |.     .      .|. .  |. .  ||.  .|. |||.|..| | . . | | |.|..  .     .   .  
ISFYDNNFYIIMEHCHKGTMFDICHRKHSQIYMIKWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRI---RNC

QRSMLEDQLNTVTTPMYRSPEMLD--TWSNNPIGPKVDIWALGCILYFLCYRKHPYEDGGKLRIINANYMLPPDP------------QY-QCFSDIIRGC
    .  .    ||.... || .|    .| ||  |.||.|.| ..| || || |..   |.  ||     .  |             . | | ...  |
SFQDMQNEMQRNTTFHWMAPEQMDPHIFPNYPINEKIDIYAYGIVMYILCFRKTPFQQ--KMSVINIMCYWCEFPGRPNLGPQFIHFDCPQNFHNLMMRC

LKVNPFERLDITMVLEGL
.  ||  | .   ... |
WCQNPNKRPNFNEIIQIL
Kinase auxillin.AA STE 50-309 21 4.2e-29 99.97 In-house 1-345 (359) Show / Hide 
Range on Protein: 50-309
Range on HMM: 1-345/359
Sequence Identity: 21% (76 aa)

LRIKCVIAEGGYAFVYVAQDVQ---------------TGTEYALKRLIGADM-----------------QASTAIINEINIHKQLSG-HENIVAFVGSSY
...  .| .|..  || | ..                ||. .| |..   .                  .    |..||.|.|...  |.||| . |. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TAPS-TQLGAQYLLLTELCKGGSLVDCFRTNNAPFNP-------------TCVLRIFYQMARA-VASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGS
     .. . .  .  |.. |||| |  ...  ...|             . . .| .|  ..  . |||.   | |||||  | |.     .|||||| 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLCDFGV

AS--TEVLSPTFEWSANQRSM----LED-QLNTVT-TPMYRSPEMLDTWS---NNPIGPKVDIWALGCILYFLCYRKHPYEDGGKL----RIINANYML-
..  |. ..   . |.|          . . ||.. || . .||...  .   ... . |.||| ||| .  ..  |.|. |.  .    .|.. ..|  
CGQLTDSMANI-Q-SNN-I-IDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ

------------PPDPQY---------------------QCFSDIIRGCLKVNPFER
            || |.                      ..| | |. ||. .| .|
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKR
Kinase auxillin.AA CAMKL 50-202 26 4.8e-23 70.25 In-house 1-176 (297) Show / Hide 
Range on Protein: 50-202
Range on HMM: 1-176/297
Sequence Identity: 26% (47 aa)

LRIKCVIAEGGYAFVYVAQD-VQTGTEYALKRLI--GADMQASTA-------------IINEINIHKQLS--GHENIVAFVGSSYTAPS-TQLGAQYLLL
 ||  .. .|... |  |..   ||...| | .   .. .   .              |  ||.|.|.|.  .|.||. .    .|     .   .. | 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

TELCKGGS--LVDCFRTNN---APFNPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDK--QIKLCDFGSA
.|.| ||.  | |  . .     .. .    |.| |.  ||. .||.   |.||||| || |. ...  .||..||| .
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG--IVHRDIKPENILLDENGNNNIKIIDFGFS
Kinase auxillin.AA Pkinase 230-319 21 3e-14 51.47 Pfam 174-293 (293) Show / Hide 
Range on Protein: 230-319
Range on HMM: 174-293/293
Sequence Identity: 21% (26 aa)

TPMYRSPEMLDTWSNNPIGPKVDIWALGCILYFLCYRKHPYEDG------GKLRIINANYMLPPDPQY------------------------QCFSDIIR
|| |..|| .   .....|||||.|..||||| .. .. |. .        .. .|. . . |.. ..                        . . |.|.
TPWYMAPEVIR--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

GCLKVNPFERLDITMVLEG--L
.||...| .|. .. .|.   .
WCLCKDPKKRPTAEQILQHPWF
Kinase auxillin.AA TyrKc 50-319 18 4.3e-10 -59.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 50-319
Range on HMM: 1-280/280
Sequence Identity: 18% (57 aa)

LRIKCVIAEGGYAFVYVAQDVQTGTEYALKRLIGADMQASTAIINEINIHKQL-SGHENIVAFVGSSYTAPSTQLG------AQYLLLTELCKGGSLVDC
.. . .. || .  || ..     .. | | |         ....|..| ..|   |.|||...|   .      |       ......|....|.| | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQ-----GRNFMYIEPLMIVMEYMPHGDLKDY

FRTNNAPFNPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGSASTEVLSPTFEWSANQRSMLED-------QLNTVTT-PMYR
 | .   ...   | . .| |.  . |||.  .. |||.   | |.|.....| .|||      ||         |   .|       .  ....    .
LRKHRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFG------LS---------RDIYDDDQQGESKDYYRKKEHKGGK

--------SPEMLDTWSNNPIGPKVDIWALGCILY-FLCYRKHPYED------GGKL---RIINANYMLPPDP---------QYQCFSDIIRGCLKVNPF
        .|| .     .   .| |.|. |  ..  . | . ||..        .    .. . ..| .|.              .. |.. | . .| 
TMLPIRWMAPECI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPE

ERLDITMVLEGL
.|   . . | .
DRPTFSEIHECF
Kinase auxillin.AA CAMKL 248-317 31 2.1e-09 26.03 In-house 214-293 (297) Show / Hide 
Range on Protein: 248-317
Range on HMM: 214-293/297
Sequence Identity: 31% (26 aa)

GPKVDIWALGCILYFLCYRKHPYEDGG-----------KLRIINANYMLPPDPQY-QCFSDIIRGCLKVNPFERLDITMVLE
|||||||..| |||.. . . | .|             ...|.   |. |. ..  .|  |.||. |.||| .|  |  ...
GPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVSDC-RDLIRKMLQVNPEKRPTIHQIMN
Kinase auxillin.AA Pkinase_Tyr 83-200 28 2e-06 22.34 Pfam 39-156 (270) Show / Hide 
Range on Protein: 83-200
Range on HMM: 39-156/270
Sequence Identity: 28% (35 aa)

GADMQA--STAIINEINIHKQLSGHENIVAFVGSSY--TAPSTQLGAQYLLLTELCKGGSLVDCFRTN---NAPFNPTCVLRIFYQMARAVASLHSQSPP
||. ..  . . ..|..| |||  |.||| ..|  .    |.     |... .|....|.| |  |..   . |...   | . .| |.. . |.|.   
GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-----QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--

IAHRDIKIENFLIGNDKQIKLCDFG
. |||.   | |.......| ||||
CIHRDLAARNCLVTENNVVKICDFG
PTEN_C2 auxillin.AA PTEN_C2 581-715 23 8.4e-35 126.63 Pfam 1-141 (141) Show / Hide 
Range on Protein: 581-715
Range on HMM: 1-141/141
Sequence Identity: 23% (33 aa)

PHYKNTTLVSLSC-QPVPRMTKARDGC-RIYMEVYCNGNLLLSTLQDYEKMRLY-QAGPGKIVLPINLTACGDVTVVLFHAR-KGMVRPQGLKICQFQFN
|. |  .|... . ...|.. |...|| |.|...|.| . ...|...|.... | |.. .....|.... .||| .  .| . .  . .   ....|.||
PPPKPLFLHCIIMDHGIPNF-KQGGGCWRPYIQIYQNDQKVFYTCKKYWHCKKYKQQKCCIFKFPQPCPVQGDVKIQCYHKGPSDLPWMYEECMFRFWFN

TGFIPEPETLITFTNQDLDDLPDP---EQVTPRFCVSLSLAV
|.||.. ....||. ..||.. ..   .. .| |.| . .  
TCFIEHNNNRLTFPKNELDKAWKDKKWKRFPPDFKVEVVFSE
DnaJ auxillin.AA DnaJ 1110-1150 41 4.6e-08 32.88 Pfam 13-52 (65) Show / Hide 
Range on Protein: 1110-1150
Range on HMM: 13-52/65
Sequence Identity: 41% (17 aa)

TPTEVKKAYRRACLAVHPDKHNGTENEEIAKLIFMELNNAW
.. |.|||||. .| .||||. . .  | |.  |.|.|.|.
SDEEIKKAYRKLALKYHPDKNPDDPE-EEAEEKFKEINEAY
DnaJ auxillin.AA DnaJ 1081-1158 20 2.8e-05 23.28 SMART 1-72 (72) Show / Hide 
Range on Protein: 1081-1158
Range on HMM: 1-72/72
Sequence Identity: 20% (18 aa)

NNIRALLCSMHTVLWDNAKWQRCEMSTMVTPTEVKKAYRRACLAVHPDKHNGTEN----------EEIAKLIFMELNNAWTDFENDAT
 .  ..|   ..                 .. |.|||||. .. .||||..| .           .| |.  |.|.| |.    ..  
RDYYEILGVPRD----------------ADDDEIKKAYRKLAKKYHPDKNPGDPERSCWKLCWEEKEEAEEKFKEINEAYEVLSDPEK