bt

Species: Fruit Fly
Alias: projectin, titin, l(2)2, Projectin, l(4)2, CT8086, lethal(4) Powell, Tennessee-2, CG1479, l(4)21, l(4)23, C-protein, l(2)23, bt, CG10285, l(4)102CDa, myosin LCK, PROJECTIN, SFO055, l(4)PT-2, Prj: Projectin, l(4)38, l(4)37, twitchin
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 102D5--E1,

Classification

Group: CAMK
Family: MLCK

Sequence

Name Sequence Type Origin Length Description Download
bt.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 256 Kinase domain by global Sugen HMM Fasta, JSON
bt.AA Protein Various 1038 None Fasta, JSON

Protein domain

Protein domains of bt.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
I-set bt.AA I-set 3-46 28 6.5e-10 36.15 Pfam 31-76 (92) Show / Hide
Range on Protein: 3-46
Range on HMM: 31-76/92
Sequence Identity: 28% (13 aa)

EVQWLRNGEEIKP-DKRIQIVKDG-RKRKLVIKDCKVTDAGQFKCT
.|.|...|....| ..|.|.. ||    .| |....  |.|. .|.
QVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCV

I-set bt.AA I-set 94-147 25 6e-06 22.66 Pfam 34-92 (92) Show / Hide
Range on Protein: 94-147
Range on HMM: 34-92/92
Sequence Identity: 25% (15 aa)

WKFNGEPIVP-SESIEIKNMGGGKHQLIFSSLDMSNEGEITC----ESGQLSSKCKLSI
|. .|.|. | |. . ... |.| . |..|  . . ||. ||    ..|. .....| .
WFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IG bt.AA IG 68-148 11 0.036217 9.77 SMART 1-58 (58) Show / Hide
Range on Protein: 68-148
Range on HMM: 1-58/58
Sequence Identity: 11% (10 aa)

LKDTEAVEREKLILDIELQDQTAPCDWKFNGEPIVPSESIEIKNMGGGKHQLIFSSLDMSNE---GEITCESG--QLSS--KCKLSIR
 . ....| | . |    .       |.                       |.. .. ....   |. .|.    | .|    .|...
PP-VTVKEGETVTLTC-VS----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ

I-set bt.AA I-set 191-242 25 0.070778 8.88 Pfam 35-89 (92) Show / Hide
Range on Protein: 191-242
Range on HMM: 35-89/92
Sequence Identity: 25% (14 aa)

FKDGKPLPV--KDVEVAVTD-DKVTFKIKKPSRDLSGPYQIKISNGQGEDTKDVQ
||||.||..  . . .  .. .  |. |..  .| .| | .. .|  ||......
FKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAE

FN3 bt.AA FN3 249-334 22 3.1e-15 57.87 SMART 1-69 (69) Show / Hide
Range on Protein: 249-334
Range on HMM: 1-69/69
Sequence Identity: 22% (23 aa)

PQPPQD---VDITDVYQT------SCVVSFNPPSDDGGTPITKYVIERQDLSKKHGWESVAEVLPSEPCLKKIDDLIPK----KQYRFRIRAVNA--IGQ
| ||..   . .|||  |      |...| .||       |. |.                          ....| |     ..|.||.||||.   |.
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGE

S
.
G

FN3 bt.AA FN3 352-435 29 9.1e-19 69.59 SMART 1-69 (69) Show / Hide
Range on Protein: 352-435
Range on HMM: 1-69/69
Sequence Identity: 29% (29 aa)

PGKPKA---VDLTDWDKD------HADLKWEAPETDGGDPITAYIVEYKEKFSNDWVSGKEVDGDARTATVDGLKEG----QQYEFRVRAVNR--AGPG
|| |.    . .||....      .. |.|..|           ||.|.                   .||.|||.|    ..|||||||||.  ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-----------IVGYR-------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

I-set bt.AA I-set 453-544 28 5.3e-13 46.63 Pfam 1-92 (92) Show / Hide
Range on Protein: 453-544
Range on HMM: 1-92/92
Sequence Identity: 28% (27 aa)

PFIVGEGLKNVTVKKGQTIRFDIKYDGEPEPAATWVKGTDNLKFD--NQRICLDQLE-RNSSITIKKSVRKDTGKYKLVLSNSSGTIESEAQVVV
| ..    |.|.|. |.|.||. . .|.|.|  .| |.  . .    ..|.  .. .  ... ||..  . |.|||. | .||.|. |..|.. |
PKFTQKP-KDVEVQEGETARFECQVTGDPPPQVSWFKD--GQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IG bt.AA IG 460-545 16 1.2e-07 32.65 SMART 1-58 (58) Show / Hide
Range on Protein: 460-545
Range on HMM: 1-58/58
Sequence Identity: 16% (15 aa)

LKNVTVKKGQTIRFDIKYDGEPEPAATWVKGTDNLKFDNQRICLDQLERNSSITIKKSVRKDT---GKYKLVLSNSSGTIES--EAQVVVL
 . |||| |.|...   .        .|                        .|| .  . |.   | |  . .  .|...|  .... |.
PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

FN3 bt.AA FN3 548-632 21 3.4e-14 54.42 SMART 1-69 (69) Show / Hide
Range on Protein: 548-632
Range on HMM: 1-69/69
Sequence Identity: 21% (21 aa)

PLPPGGP--FEPEEIRAS------HIKMKWKRPDDDGGCEISGYALERMDEETGRWIPAGEVGPNETSFDFKGLTPN----KKYKFRVKAINK--EGES
| ||..|  .. ... ..      ..  .||.|       | ||                        . ..||.|.    ..|.|||.|.|.   ||.
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 bt.AA FN3 650-733 26 3.2e-17 64.44 SMART 1-69 (69) Show / Hide
Range on Protein: 650-733
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PSPPSQ---PVIDDYDNK------SVLLKWKRPPSDGGRPITHYIVEIKDKFAPSWSEVAKTDDPNPECNVEGLKEK----MVYQFRVRAVNK--AGPS
|.||.    ... | ..       || |.||.|       |..|.                       . |.|||.       |.|||||||.  ||..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

I-set bt.AA I-set 751-842 29 1.7e-13 48.27 Pfam 1-92 (92) Show / Hide
Range on Protein: 751-842
Range on HMM: 1-92/92
Sequence Identity: 29% (28 aa)

PQIDRSTFKRVTIKSGRTHKWSVDVLGEPIPELHWSWRDDIPLTN-GDRIKIENVD-YHTDFSITNVLRKDSGFYTLKAENRNGIDRETVELVV
|....   |.|... | | . ...| |.| |.  |    . ||.. .||... ... ... . |.|| . |.| || .|.|. | .  |.|| |
PKFTQKP-KDVEVQEGETARFECQVTGDPPPQVSWFKD-GQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IG bt.AA IG 758-843 19 1e-06 29.46 SMART 1-58 (58) Show / Hide
Range on Protein: 758-843
Range on HMM: 1-58/58
Sequence Identity: 19% (18 aa)

FKRVTIKSGRTHKWSVDVLGEPIPELHWSWRDDIPLTNGDRIKIENVDYHTDFSITNVLRKDS---GFYTLKAENRNGIDRE--TVELVVL
 . || | | | . .  |      ...|.                       . | || . ||   | |.  |.  .| .    ...| |.
PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

FN3 bt.AA FN3 846-932 28 5.7e-17 63.63 SMART 1-69 (69) Show / Hide
Range on Protein: 846-932
Range on HMM: 1-69/69
Sequence Identity: 28% (29 aa)

PSSPKGP--LAVSDVTAS------GCKLQWKKPEDDGGVPIKEYVVEKMDTATGKWVRVGRSPGEKEPPSFDVTGLSLG----SEYMFRVSAVNE--EGE
|..|..|  | |.|||..       . |.||.|       | .|.                         . ||||. |    .|| |||.|||.   ||
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGE

S
.
G

FN3 bt.AA FN3 950-1035 21 2.9e-09 38.0 SMART 1-69 (69) Show / Hide
Range on Protein: 950-1035
Range on HMM: 1-69/69
Sequence Identity: 21% (21 aa)

PNKPGT---PEVTDYDNQ------SISLKWAAPNNDGGAPIQKYIIEKKNKNKTEWEKALEIPGDQLEATVAGLQEY----GEYQFRVLVAYKAYLYDG
|  |.    ..||| ..       |..|.| .|       |  |.                       .|| ||...     ||.||| . ..     |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG