Gene Fak56D (Fruit Fly)

Fak56D

Species: Fruit Fly
Alias: DmFAK, FAK, DFak56, Dfak, focal adhesion kinase homolog, DFAK, Fak, DFak, CT28129, Dfak56, SFO032, CG10023, Fak56, Fak56D
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 56D15,

Classification

Group: TK
Family: FAK

Sequence

Name Sequence Type Origin Length Description Download
Fak56D.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 280 Kinase domain by global Sugen HMM Fasta, JSON
Fak56D.AA Protein Various 1200 None Fasta, JSON

Protein domain

Protein domains of Fak56D.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B41 Fak56D.AA B41 18-267 12 1e-06 24.53 SMART 1-232 (232) Show / Hide 
Range on Protein: 18-267
Range on HMM: 1-232/232
Sequence Identity: 12% (34 aa)

NSEEYLIHVHMPNKSFKAVRFNVKETVFHVIRRTVEDLGTDGRTPSIQRYACRMLNMITKEVIWLARSTSMQKVLSHILTPGCSNVDCPNNQSELDEVLL
....  ..|.... . . .... . |.  ...  .. .|.     . . .. .. ..  .                               .. ||  . 
SPKPRFCRVYFMDGTTLEFEVDSSTTGQDLCDHVCRHCGI--SPREHWYFGLWYEDPHED-------------------------------RHWLD--HW

EHGRRITDN----RVWRVELRVRYVPNNI---QELFEEDKATCFYYFNQVKEDFIQANVTAIDTEVAVQLCCLGIRHYFKNITVKAPDKKQHIDYIEKEI
 . ...  .      |.. .||.. |..    .....||...  |.. |...|..| . .  ..| ..||..| ... ...   .....| . ....|..
KTIMKQDVKWHKSEPWTLHFRVKFYPPDWHGFPNQLQEDPTRYNYFYLQCRHDILQGRHPCPHEEECLQLAALQVQIEYGDYDPEETNNKKMTKHVQKYK

GFKSFLPQSVIATSK---------PKNLKKLIQVGYKKVYNYNDIEYLTRFFDLLKNIY-LTNFEQF
. | |||...| . |         .| ..| |.  .|.. . .  |   ... ...    .   | |
SYKRFLPKQWIDSIKQSFMHYQMHHKEWRKRIMEWHKNHCGMTPEEAKLKYLQICQRWPPMYGVEHF
Kinase Fak56D.AA FAK 457-741 72 2.6e-234 784.69 In-house 1-285 (285) Show / Hide 
Range on Protein: 457-741
Range on HMM: 1-285/285
Sequence Identity: 72% (208 aa)

ITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVMPIWI
||....||.|||||||.|.||..|.|||||||||||||||||||||||||.|||||||||...|....|.|..|||||..||||||..|||||..|||||
ITLNRCIGEGQFGDVYQGVYTNHKNGKGKNLAGNGKNSNSDQRNADSRPDKIQVAIKTCKKCCDDDNKEKFMQEAYIMKQFDHPHIVKLIGICEEMPIWI

VMELAKLGELRAYLKTNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWMSPESINF
.|||.|.||||.||..|...|.|.||..|||||..|..||||||||||||||||||||||.||||.|||||||..|.|||...|...|||||||||||||
IMELCKYGELRHYLQRNKNSLKHATLILYCYQLCMAMAYLESKKFVHRDIAARNVLVSSPDCVKLGDFGLSRWMHDHSYYKASPKGKLPIKWMSPESINF

RRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETLHEILI
|||||||||||||||.|||||.||||||.|||.|||...|||||||.||||||.|||||..||||.|.|||.||..|..| .|  
RRFTTASDVWMFGVCMWEILMYGVKPFQWVKNNDVIGRIENGERLPMPPNCPPTLYSLMTRCWAYDPSKRPRFKELKCQLKDIYQ
Kinase Fak56D.AA TyrKc 457-736 37 1.5e-125 424.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 457-736
Range on HMM: 1-280/280
Sequence Identity: 37% (117 aa)

ITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEKTENFLAEAYIMQKF--DHPHIIRLIGICSV---
||   |.| |.|| || ||..                              ||||.|..|..      | |. || || |.  .||.|.||.|.|.    
ITLGKKLGEGAFGEVYKGTWK------------------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGR

-----MPIWIVMELAKLGELRAYLKTNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQ-------SYYHST
      |..||||....| |. ||. . ..|.. .||..|.| .   .||.||...|||.||||.||... .|| .|||||| . |        .||...
NFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKK

---PTVA-LPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQG-----VKNSDVILKLENGERLPLPPN--------CPPRLYSLMSQCWAYE
    . . |||.||.||.||...|||.||||.||||.|||. .| .|  |     ..|..|| ....|.|.| |||        ||. .|..|.|||...
EHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHED

PLKRPNFKRIKETL
| .||.|. |.| .
PEDRPTFSEIHECF
Kinase Fak56D.AA Pkinase_Tyr 457-736 40 2.2e-125 425.24 Pfam 1-270 (270) Show / Hide 
Range on Protein: 457-736
Range on HMM: 1-270/270
Sequence Identity: 40% (119 aa)

ITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEK--TENFLAEAYIMQKF-DHPHIIRLIGICS-V-
||   |.| |.||.|| ||..                        |   . |.||.|..| . ..|    | |..|| || .. .||.|.||.|.|.   
ITFGKKLGEGAFGEVYKGTWKG-----------------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQG

MP--IWIVMELAKLGELRAYLKTN---SERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWV-SDQSY-YHSTPTVAL
 |  |.||||....| |. ||...    ..|.. .||..|.| . ...|||||...|||.||||.||... .|| .||||.| . .|  | . .. .  |
EPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-L

PIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKP-FQGVKNSDVILKL-ENGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETL
|||||.||.||...|||.||||.|||..|||. .| .| ..|..|..|. .. |.|.|.| |.|||. .|.|| |||.|.| .|| |. | | |
PIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Fak56D.AA TK 457-736 23 1.9e-111 375.04 In-house 1-486 (486) Show / Hide 
Range on Protein: 457-736
Range on HMM: 1-486/486
Sequence Identity: 23% (117 aa)

ITPSAKIGVGQFG---DVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEKTE-------------NFLAEAYIMQKFD--
||   |.| ||||   .|| |..  .. ..||. . . . .    .  ...  ...||.|..|. |. ...|             .||.|| .|....  
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMT-V-TLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHS

---HPHIIRLIGICSV-------------MPIWIVMELAKLGE----LRAYLKTNSER------------------------------------------
   ||.|.||.|.|.               |..||||....|     || ||......                                          
LGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQ

---------------------------------LSHGTLLKYCYQLSTALSYLESK------KFVHRDIAARNVLVSSPTC-----------VKLADFG-
                                 |.  .|| .|.|.. ...||.||      .|||||.||||.||..              .|.|||| 
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL

-------LSRWVSD------------------------QSYYHSTPTVALPIKWMSPESIN---------FRRFTTASDVWMFGVCIWEILMLGVKPFQG
       |.| . .                        |.||....   |||.||.||..|         ...|||.||||.|||..|||...| .|. |
SRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYG

-VKN---------SDVILKLEN------------GERLPLP--PNCP--------------PRLYSLMSQCWAYEPLKRPNFKRIKETL
 . |          .|. .|..            |.|...|  |.||              . .| || |||.|.| .||.|. ..| |
GMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Fak56D.AA Ack 506-736 38 1.1e-86 292.37 In-house 26-266 (266) Show / Hide 
Range on Protein: 506-736
Range on HMM: 26-266/266
Sequence Identity: 38% (93 aa)

DVIQVAIKTCKAN--DDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVMPI-WIVMELAKLGELRAYLKTNSERLSHG---TLLKYCYQLSTALSYLESK
..||||.|  .      |.  . || |. || . ||||..|| |.    |    |.||| .| |   |.    | ..    ||. .| |. ....|||.|
KHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRK-HCRTAFFLIHTLCDFCMQIAMGMRYLEMK

KFVHRDIAARNVLVSSP-TCVKLADFGLSRW-VSDQSYYHSTPTV--ALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKL
 ..||| ||||.|. |.   || .||||.|       || . ...   .|. |. ||....|.|. |||||||||..||    | .|. |.  .... |.
RCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGVTLWEMFSYGEEPWAGCNGYQILQKI

E-NGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETL
. .||||| |. ||...|..| |||. .| .|| |  |.. |
DKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase Fak56D.AA UTK 509-736 34 3.3e-86 292.69 In-house 31-296 (296) Show / Hide 
Range on Protein: 509-736
Range on HMM: 31-296/296
Sequence Identity: 34% (93 aa)

QVAIKTCKANDDPEKTEN----FLAEAY---IMQKFD-HPHIIRLIGICSV-MPIWIVMELAKLGELRAYLKTNSE-------RLSHGTLLKYCYQLSTA
.||.|.|.. .| ....     |. ||    .|..|. ||...||.|.|.  .|..||.|... | ||.|| ....        |.  ..|..... . .
DVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARG

LSYLESKKFVHRDIAARNVLVSSP-------TCVKLADFG---LSRWVS---------DQSYYHSTPTVALPIKWMSPESINFR-RFTTASDVWMFGVCI
..||.|..|||||.||||.|| .        . .|.||||   .|| |.         .. || ...  ..||.||.||... . ||||.|||| |||  
MQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVC

WEILMLGVKPFQGVKNSDVILKLENG--ERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETL
|||.. | .|. |  | .|.. ..||   |.| |. || ..| || .||.|.| .||.|... ...
WEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase Fak56D.AA Syk 507-730 40 1.3e-83 284.08 In-house 31-257 (257) Show / Hide 
Range on Protein: 507-730
Range on HMM: 31-257/257
Sequence Identity: 40% (91 aa)

VIQVAIKTCK-ANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVMPIWIVMELAKLGELRAYLKTNSERLSHGTLLKYCY-QLSTALSYLESKKFVHR
.|.||||. |    .|  .. |..|| .|.. |||.|.|.||||   .   |||.| || .  ||. . .  .    |.  . | .    |||.|.||||
WIKVAIKMLKADHNQPADKQEFMREAQVMCQLDHPCIVRMIGICHAEMMMMVMEMAELGPMHKYLQQHRHEITANNVLELWHTQVAMGMCYLEEKHFVHR

DIAARNVLVSSPTCVKLADFGLSRWV-SDQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPL
| ||||||    .  |  |||.|.    | .|| .|     |.||  ||.|... |  .|||| ||| .|| . .| ||  . |...|.  .|||.|.. 
DLAARNVLLVNRHYAKISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEMKGQEVMKFIENGHRMNC

PPNCPPRLYSLMSQCWAYEPLKRPNFK
|. ||. .|.||..|| |..  || | 
PNGCPQEMYQLMNKCWIYKWCDRPTFV
Kinase Fak56D.AA TK-Unique 457-736 30 1.5e-83 283.86 In-house 1-294 (294) Show / Hide 
Range on Protein: 457-736
Range on HMM: 1-294/294
Sequence Identity: 30% (96 aa)

ITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEKTENFLAEAYIMQKFD-HPHIIRLIGICS-VM-P
..   .|| |.|| |. |... ..                      .. . ..||.|..|.| ....  .|| |. .|.. . ||.|....|.|     |
LEVGDVIGEGAFGQVWRGEVWGIW---------------------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEP

IWIVMELAKLGELRAYLKTNSER-------------------------LSHGTLLKYCYQLSTALSYLES--KKFVHRDIAARNVLVSSPTCVKLADFGL
  |.|| .  | |. ||.|.                            .| ..|. ...|.  ...||.|  ||.||||..|||||...   .|..|||.
WMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGM

SRWVSDQSYYHST-PTVALPIKWMSPESIN--FRRF-TTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNC-PPRLYSLMSQCWAY
.| |..   | ..     .||.||.|||.    . . || ||||.||| .|||. ||  |. |....|.. ....| |.|.|..| ....|.||..|| .
ARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQW

EPLKRPNFKRIKETL
|| .||.|  ||  |
EPEERPSFRQIKHRL
Kinase Fak56D.AA Eph 457-736 36 7.9e-83 278.06 In-house 1-264 (264) Show / Hide 
Range on Protein: 457-736
Range on HMM: 1-264/264
Sequence Identity: 36% (103 aa)

ITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIG-ICSVMPIW
|.  . || |.||.|. |.  ||.  . . .                      ||||| ||     .  .||.|| ||  ||||.|||| | . .  |. 
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVD--------------------PVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVM

IVMELAKLGELRAYLKTNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQS----YYHSTPTVALPIKWMSP
|| |   .| | ..|... .... . |.   . .  .  || .  .|||| ||||.||.|  . | .|||||| . |..     | ..     ||.|  |
IVTEYMENGSLDSFLRQHDGQFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAP

ESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETL
| | .|.||.||||| .|. .||..  | .|.    | |||   | | ||| |..||. |. || .||.... .|| |. |  .|
EAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase Fak56D.AA Fer 457-737 31 3.5e-81 276.03 In-house 1-283 (283) Show / Hide 
Range on Protein: 457-737
Range on HMM: 1-283/283
Sequence Identity: 31% (96 aa)

ITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNAD---SRPDVIQVAIKTCKANDDPEK-TENFLAEAYIMQK-FDHPHIIRLIGICS-
.|   |.| | ||.|| |.                     ...  .   . .. . |. |.||..|. ..  . |..||.||.. .|||......|.|. 
VTLGKKLGEGAFGEVYKGR-------------------R-TLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVD

VMPIWIVMELAKLGELRAYLKTNSER-LSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVK---LADFGLSRWVSDQSYYHSTP--TVAL
  || ||||... | |. |||.|... .|  .....||| .  . ||.||. .||||||||.|..    .|   ..|||.||  ||  |  . .     .
EQPIMIVMEFCNGGSLDSYLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKV

PIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQG----VKNSDV----ILK-LENGERLPLPPNCPPRLYSLMS-QCWAYEPLKRPNFKRIKE
||.|..||..... .....||| ||| .||| . | .|. |    .|.  |    . .  ..| ..|.|...||.....|  |||...| .||..| |..
PIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQ

TLH
.|.
KLK
Kinase Fak56D.AA Src 508-736 41 5.7e-79 267.94 In-house 24-255 (255) Show / Hide 
Range on Protein: 508-736
Range on HMM: 24-255/255
Sequence Identity: 41% (97 aa)

IQVAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVM-PIWIVMELAKLGELRAYLK-TNSER-LSHGTLLKYCYQLSTALSYLESKKFVHR
..||.|| |. .   ..| ||.|| || |..|.....|  .||   || || |. . | | .||| .  .| |.  .|.    | .   .||||....||
TKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHR

DIAARNVLVSSPTCVKLADFGLSRWVS--DQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLP
| |||||||.   ..| ||||| | .   |  |  ..    .||||. || ||..|||. |||| ||. ..||   |  |  | .| .|. ..|.| |.|
DLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARH-GAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMP

LPPNCPPRLYS-LMSQCWAYEPLKRPNFKRIKETL
 |.|||..||  .| |||  .| .|| |... . |
CPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Fak56D.AA EGFR 508-737 39 1.8e-78 260.11 In-house 29-258 (258) Show / Hide 
Range on Protein: 508-737
Range on HMM: 29-258/258
Sequence Identity: 39% (90 aa)

IQVAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVMPIWIVMELAKLGELRAYLKTNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIA
| ||||  . . .|. .| .| |||.|   ||||..||.|.|    . .|  .  .| |  |.. . ...    || .|.|    ..||| .. |||| |
IPVAIKVLREQTGPKANEEMLDEAYVMASVDHPHLVRLLGVCMHSQMQLVTQYMPYGCLLDYVRQHKDNIGSQHLLNWCVQIAKGMQYLEEHRMVHRDLA

ARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNC
|||||| ||  || .||||..  .  .         .|||||  |.| .|..| .|||| .|| .||..  | ||..|.. ...   ||.||||| ||.|
ARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQGGKMPIKWMALECIHHRCYTHQSDVWSYGVTCWELMTFGQKPYDGIPAREIPDLLEKGERLPQPPIC

PPRLYSLMSQCWAYEPLKRPNFKRIKETLH
   .| .| .||   .  || || . | ..
TIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase Fak56D.AA S_TKc 457-740 22 1.8e-48 168.24 SMART 1-231 (231) Show / Hide 
Range on Protein: 457-740
Range on HMM: 1-231/231
Sequence Identity: 22% (66 aa)

ITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVMPIWI
 .   ||| | || || .. .                            .  .||||  |        |... |  |..| .||.|..|....    ...
YEILRKIGKGAFGKVYKCRHKK---------------------------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYM

VMELAKL--GELRAYLKTNSER-----LSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWM
|||..    |.|. |.| .  .     ..  .  .|.||.  || |. |....|||.   |.|...  ..|..||||.| .          |.     .|
VMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYM

SPESINFRRFTT-ASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKE-----TLHEIL
.|| .    ... ..|.| .|....| |  |  ||.   . ....|.            .| . .....|. ..| |||    . .      .|. .
APEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Fak56D.AA Pkinase 457-736 21 1.4e-39 141.07 Pfam 1-293 (293) Show / Hide 
Range on Protein: 457-736
Range on HMM: 1-293/293
Sequence Identity: 21% (70 aa)

ITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKT-CKANDDPEKTENFLA--EAYIMQKFDHPHIIRLIGIC-SVM
..   ||| | || || ..                                 .||.|. .| .....| .. .   |..||....||.|.||.... .  
YHIGRKIGSGSFGCVYKCHHKGTGK---------------------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKD

PIWIVMELAKLG----ELRAYLK-TNSERL--SHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVS-SPTC---VKLADFGLSR---WVSDQSYYHS
 |..|||..  |    .| .|..  .. ..  |  .. .|.||.  .| |. |....|||.   |.|..  ...   ||..||||..   . ... ... 
HIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF

TPTVALPIKWMSPESIN-FRRFTTASDVWMFGVCIWEILMLGVKPFQGV----KNSDVILKLENGERLPLPPNCP-----------------------PR
. |    . .|.|| |.  .  ....|.| .|. ..| |  |  ||.|     .  | . ....  . ||. ..|                       . 
CGT----PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEE

LYSLMSQCWAYEPLKRPNFKRIKET--L
. .... |... | |||... |..   .
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Fak56D.AA Src 457-476 45 0.000108 11.82 In-house 1-20 (255) Show / Hide 
Range on Protein: 457-476
Range on HMM: 1-20/255
Sequence Identity: 45% (9 aa)

ITPSAKIGVGQFGDVYVGTY
|.   |.| ||||.|. |..
IKLCRKLGQGQFGEVWMGYW
Kinase Fak56D.AA UTK 457-477 28 0.000131 11.69 In-house 1-21 (296) Show / Hide 
Range on Protein: 457-477
Range on HMM: 1-21/296
Sequence Identity: 28% (6 aa)

ITPSAKIGVGQFGDVYVGTYT
. .....| |.||.|.....|
VQLGRQLGQGAFGEVHKARFT
Focal_AT Fak56D.AA Focal_AT 945-1083 56 4.3e-92 317.04 Pfam 1-139 (139) Show / Hide 
Range on Protein: 945-1083
Range on HMM: 1-139/139
Sequence Identity: 56% (79 aa)

SRPPNRADDEVYCATTLVVKSIMALSQGVEKANTEGYLELVKNVGVKLRNLLTSVDKISIIFPAQALKEVQMAHQVLSKDMHELVSAMRLAQQYSDTTLD
... .|.||.|||... ||||.|.....|.|...|.|...|||||..||.||.|||.|. ..|||...|..||| ||.||||||.|.|||||||..||||
TANMDRSDDYVYCNVMQVVKSVMEMKNKVHKLPSEEYVNMVKNVGLELRKLLQSVDEIYPSLPAQCHREIEMAHKVLNKDMHELISKMRLAQQYAMTTLD

CEYRKSMLSAAHVLAMDAKNLFDVVDSIRQRYQHLFPPS
 |..|.||.||||||||||||.|.||..|.|.||...| 
QECKKQMLTAAHVLAMDAKNLLDAVDQARVRMQHAHMPH