Gene CG11573 (Fruit Fly)

CG11573

Species: Fruit Fly
Alias: CT33540, CG11573, SFO092
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 26C2,

Classification

Group: TK
Family: DDR

Sequence

Name Sequence Type Origin Length Description Download
CG11573.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 290 Kinase domain by global Sugen HMM Fasta, JSON
CG11573.AA Protein Various 820 None Fasta, JSON

Protein domain

Protein domains of CG11573.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
F5_F8_type_C CG11573.AA F5_F8_type_C 10-148 24 5.5e-24 84.53 Pfam 1-140 (140) Show / Hide 
Range on Protein: 10-148
Range on HMM: 1-140/140
Sequence Identity: 24% (36 aa)

QITASSAHDMGNVGPQHARLKIDNN-G--GAWCP-KHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPG-LK-KWIRWRSLQG
|||||| .. .. ..... . ||.|    ..|.. |.  . .  ...||||  .. ......|.| . |.  ... .| |.|   |  . .|.  .. .|
QITASSQWSGYWGNGWPPDNAIDGNGYPNTFWHSQKWS-NNDDPQWIQVDLGKPYKITGVVYQWRQDGGN--GWVKKYKIQYSNDGGDESNWTTYKDHDG

KEVLPGNINTYSEVENVLQPSVFASKVRLYPY-SQYDRTVCLRAEI
  | .|| .    | |.. |.. |  ||..|   ..    ..|.|.
-KVFYGN-DND-PVKNMFFPPIKARYVRIHPTSWNNHNWWAMRWEF
FA58C CG11573.AA FA58C 1-151 21 1.7e-08 35.43 SMART 8-199 (199) Show / Hide 
Range on Protein: 1-151
Range on HMM: 8-199/199
Sequence Identity: 21% (41 aa)

MESGAIADFQITASSAHDMG------NVGPQHARLKIDNN-----GGAWCPKHMVS------RGLTEYLQVDLLG-VHLVSAIRTQGRF------GKGQG
||.|.|.|.||||||.|  .      . .| .|||  .       ..||||.. .          .. ..|||.. .|.|... |....        ...
MEGGHIPDWQITASSSHYWNRDMPWWYWWPHIARLNGNGSNHDYWDNAWCPWKNDYEDWIFDYHCPHWWLVDLGRKTHRVTGV-TITGRRRRGHGWGHDD

QEYTEAY-VIEYWRPGL-----KKWIRWR------SLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQ------YDRTVCLRAEIVGC
. ..  . .  ..|...     . |. ..      .. . .| .||..    . |.. | . |  .|..|         . ...|.| |. ||
WWTYYWMMYKDDRRDNNERQNGHTWTTYKDFWIEHGTGNSMVFYGNWDNNHPWHNMFHPPMVARYIRIWPTWWNTNATGWHHNYCMRWELYGC
Kinase CG11573.AA DDR 515-804 56 4.6e-211 707.46 In-house 1-306 (306) Show / Hide 
Range on Protein: 515-804
Range on HMM: 1-306/306
Sequence Identity: 56% (173 aa)

LVIVEKLGSGVFGELHLCETNVLNDLTEFDSHCS-----ATLVAVATLRPGANDHLRKEFRSKAKQLAQLS-DPNVARLVGACLRDEPICIVQDYSHCLG
|..|||.|.|.|||.||||.....|..|||.||.     .|||||..|||.|..|.|..|....|...|.. .||..||||.|..|||.|....|...||
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG

DLNQFLQEHVAETSGLMAKK---------SLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGFTGR
|||||..||.||.||||..|         ..|..|.|||.||||||||.||.|||||||||||.|..|.|...|.|..|||..|..|..||...||||||
DLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGR

QSQPMPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIY-DLMCECWQRDESSRPSFR
|...||||||||||.||||||||||||.|.|..||...|.||||||.|.|..||||.....|...|...|||||.||.||| .|||.||.||.|.||||.
QRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPMCPYEIYNQLMCRCWRRDQSQRPSFE

EIHLYL
|||..|
EIHKFL
Kinase CG11573.AA TK 515-804 21 3e-85 285.66 In-house 1-486 (486) Show / Hide 
Range on Protein: 515-804
Range on HMM: 1-486/486
Sequence Identity: 21% (106 aa)

LVIVEKLGSGVFG---ELHLCETNVLNDLTEFDSHC--------------SATLVAVATLRPGANDHLRKEFR----------------SKAKQLAQ--L
.....|||.| ||   | ...| . .|.. . ...|                | |||..|..|.... . .|                 . .|.. .  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SDPNVARLVGACLRD------------EPICIVQDYSHCLGD----LNQFLQEHVAETSGLMAKKS----------------------------------
  ||. ||.|.|...            ||..||  |  ..||    | ..|...  ...    ...                                  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYM-PHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------LSFGCLVYIATQIASGMKHLEQM------NFVHRDLATRSCIIGPELC-----------VKVCSIGTV
                                |.  .|. .. |||.|| .|...      ||||||||.| | .| ..            .|..  |  
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------INRSAYA-SDYCQLEGFTGRQ------------------SQPMPIRWMAWESVL---------LGKFTTKSDVWSFAVALWEILTFAREQPYEH
        |  |  .||.  .. ...                   .  .||||||.|...          |||||||||||| | .|||.|...|..|. 
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

LSD---------KSVIENIGLIYR-------DYKMHELLPMPPNCP--------------REIYDLMCECWQRDESSRPSFREIHLYL
.|.         . |.|..    |       .      .| ||.||               |.||||..||..| . ||.|...| .|
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase CG11573.AA TyrKc 515-804 32 1.5e-71 244.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 515-804
Range on HMM: 1-280/280
Sequence Identity: 32% (103 aa)

LVIVEKLGSGVFGELHLCETNVLNDLTEFDSHCSATLVAVATLRPGANDHLRKEFRSKAKQLAQL--SDPNVARLVGACLRD-------EPICIVQDYSH
..  .|||.| ||| .... .              . ||| .|...|    |..|.. |. . .|  . ||. ||.|.|. .       ||..||  |  
ITLGKKLGEGAFGEVYKGTWK--------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEY-M

CLGDLNQFLQEHVAETSGLMAKKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAY------ASDYCQLEGFTGR
..|||...|..|  .         |.   |.....|||.|| .|...|..|||||.| | .| ...||..  |   .   .       . | . |.  |.
PHGDLKDYLRKHRPK---------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

QSQPMPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEH-----LSDKSVIENIGLIYRDYKMHELLPMPPN----CPREIYDLMCECWQRD
   ..||||||.|.   |||||||||||| | .|||.|.  .|||.      .|.. |||..   ||  .... .  |      || |.|..| .||..|
T--MLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYG-QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MSFVCCPDEMYQIMKQCWHED

ESSRPSFREIHLYL
 ..||.|.||| ..
PEDRPTFSEIHECF
Kinase CG11573.AA Trk 515-804 34 2.8e-61 206.47 In-house 1-275 (275) Show / Hide 
Range on Protein: 515-804
Range on HMM: 1-275/275
Sequence Identity: 34% (102 aa)

LVIVEKLGSGVFGELHLCETNVLNDLTEFDSHCSATLVAVATLRPGANDHLRKEFRSKAKQLAQLSDPNVARLVGACLRDEPICIVQDYSHCLGDLNQFL
.|.   || | ||   | |   |    .       ..||| ||.  ..   ||.|.  |. | .|  ... .. | |  ..|. .|  | .  ||||..|
IVLKWELGEGAFGKVFLAECYNLCPEQD------KMMVAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKH-GDLNKYL

QEHVAETSGLMAKKS------LSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYA-SDYCQLEGFTGRQSQPMPIR
. |    . ..  .       |  . . .|| ||||||  . .  |||||.||| | .| .| ||.   |    |  |  .||  ... |      .|||
RQHGPDAMCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFG--MSRDVYSHTDYYRVGHHTM-----LPIR

WMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLYL
||  ||..  |||. |||||| | .||..|. . ||.  || . ||| |       .  . |  |  ||.|.||.|  ||||.   | . ..||  .
WMPPESIMYRKFTYESDVWSFGVVMWECFTYGK-QPWYQLSNHEVIECI------HQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase CG11573.AA UTK 515-804 30 1.3e-59 202.55 In-house 1-296 (296) Show / Hide 
Range on Protein: 515-804
Range on HMM: 1-296/296
Sequence Identity: 30% (95 aa)

LVIVEKLGSGVFGELHLCETNVLNDLTEFDSHCSATLVAVATLRPGAN-DHLRK---EFRSKAK---QLAQLS-DPNVARLVGACLRDEPICIVQDYSHC
. . ..||.| ||| |...      .|. . |    .||| .....|.  . .    .|.  |.    ..|..  |||.|||| |...||..||  |  .
VQLGRQLGQGAFGEVHKAR------FTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEY-ME

LGDLNQFLQEHVAETSGLMAKKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPE-------LCVKVCSIG-----TVINRSAYASDYCQLE
 ||| ..|. |  ..    .  .|.  .... | .||.|| .|....||||||| | | ..         . .|..  |       .|.   .. | . .
NGDLRSYLRRHRPTPP--ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESY

GFTGRQSQPMPIRWMAWESVLLG-KFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESS
 .. .. ...|||||| |..  . .|||||||||| | .|||.|..| .||...|.  |.....  .|      ..| |. ||...|.|| .||. | . 
YYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGR-LPYPGMSNMQVWHQVCNGGR-----YRMPCPWDCPHPVYRLMHRCWHYDPQE

RPSFREIHLYL
||.|...   .
RPDFEDLVQQM
Kinase CG11573.AA Ror 515-801 36 6e-59 202.16 In-house 1-272 (308) Show / Hide 
Range on Protein: 515-801
Range on HMM: 1-272/308
Sequence Identity: 36% (107 aa)

LVIVEKLGSGVFGELHLCETNVLNDLTEFDSHCSATLVAVATLRPGANDHLRKEFRSKAKQLAQLSDPNVARLVGACLRDEPICIVQDYSHCLGDLNQFL
.   |.|| . ||  .  .      |.      ....||. |..  |.  ....||  ..  |.|  ||.  | |.|. |.| | .  |    |||  ||
VRFMEELGECQFGKVYKGH------LMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEY-MNHGDLHEFL

QEHVAETSGL-------MAKKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGFTGRQSQPMPIR
  ..             | |.||. .  ..||.|||.||  |  . |||||||.| | .| .. ||.   |    |  |.|||  . .    .|  ||||
IMRSPHSDHGCSSDDDRMVKSSLDHPDFLHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFG--LMRDIYSSDYYRMQH----KSW-MPIR

WMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIH
||. |... |||.. ||.||| | ||||  . . |||.  |   |||   .|        ||| | |||  || || |||    | || | .||
WMSPEAIMYGKFSEDSDIWSFGVVLWEIWSYGM-QPYYGYSNQEVIE---MI----RNRHLLPCPHNCPTWIYSLMIECWHEIPSRRPRFKDIH
Kinase CG11573.AA Musk 550-804 33 1e-56 185.88 In-house 30-282 (282) Show / Hide 
Range on Protein: 550-804
Range on HMM: 30-282/282
Sequence Identity: 33% (91 aa)

TLVAVATLRPGANDHLRKEFRSKAKQLAQLSDPNVARLVGACLRDEPICIVQDYSHCLGDLNQFLQEHVAETSGLMAKKSLS--------------FGCL
|.|||  |.  | . . . |   |  .|. . ||. .| | |    |.|    |    |||| ||.     ..     ....                 .
TMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEY-MAYGDLNEFLHSCSPHRTCSRTHQDRGMRAQVSSPGPPQLKCYHQ

VYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGFTGRQSQPMPIRWMAWESVLLGKFTTKSDVWSFAVALWEI
  .| ||| ||  |  | ||||||||| | |. .  ||.   |    |  |  ||     . | .    |||||. ||..  .||. ||||.. | ||||
LCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFG--LSRYIYHQDY-----YKGHENDHIPIRWMPPESIWYNQFTYESDVWAYGVCLWEI

LTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLYL
  .| .|||  ..   ||  |       .    |  | ||| ..| || .|||.  . ||.| .||  .
FSYA-LQPYYGMTHEEVIYYI-------RQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase CG11573.AA Eph 515-804 33 2e-53 177.75 In-house 1-264 (264) Show / Hide 
Range on Protein: 515-804
Range on HMM: 1-264/264
Sequence Identity: 33% (98 aa)

LVIVEKLGSGVFGELHLCETNVLNDLTEF--DSHCSATLVAVATLRPGANDHLRKEFRSKAKQLAQLSDPNVARLVGACLRDEPICIVQDYSHCLGDLNQ
. | . .|.| |||.      . .  .|   |      .||. ||. |. .  | .| | |  . | . ||. || |   . .|. ||  |   .| | .
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVD------PVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYME-NGSLDS

FLQEHVAETSGLMAKKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGFTGRQSQPMPIRWMAWE
|| .|            .. . || .   |||||| |  ||.|||||| |.  .  .|. ||   |     |    |   .|.    ..   |||| | |
FLRQHDG---------QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGL----SRVLEDDPSVEATYTTRGGKIPIRWTAPE

SVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLYL
 .  .|||. |||||. . .||....  | ||  .|.. ||. |   ||       || |..||. .. || .|||.| ..|| | .|.  |
AIAYRKFTSASDVWSYGIVMWEVMSYG-ERPYWDMSNQDVIKAIEQGYR-------LPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase CG11573.AA CTKA 636-804 38 7.9e-43 141.66 In-house 134-290 (290) Show / Hide 
Range on Protein: 636-804
Range on HMM: 134-290/290
Sequence Identity: 38% (66 aa)

VYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGFTGRQSQPMPIRWMAWESVLLGKFTTKSDVWSFAVALWEI
|| | ||| ||  |  | ||||||| | |..|    .|.   |    ..  . .|      .   .  ||.|||| | .  |||.. ||||.| | ||||
VYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYY------YVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEI

LTFAREQPYEHLSDKSVIENIGLIYRDYKMH--ELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLYL
.... | |. |.||. | .        |  |  . ||.|.|||  .| .| |||.     ||.|  .   |
MSMG-EKPWRHMSDQEVCQA-------YTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase CG11573.AA Pkinase_Tyr 703-804 50 1.8e-38 130.94 Pfam 175-270 (270) Show / Hide 
Range on Protein: 703-804
Range on HMM: 175-270/270
Sequence Identity: 50% (53 aa)

PMPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQP-YEHLSDKSVIENI-GLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREI
..||.||| |.   |||||||||||| | .|||.|. . || |. .|.  |.| |    ||       .|.|.||| ||||||..||. | . ||.|.||
KLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGE-QPTYPGMSNEEVYEYIYEDGYR-------MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI

HLYL
|  |
HEQL
Kinase CG11573.AA Pkinase_Tyr 515-675 34 4.5e-33 112.62 Pfam 1-153 (270) Show / Hide 
Range on Protein: 515-675
Range on HMM: 1-153/270
Sequence Identity: 34% (58 aa)

LVIVEKLGSGVFGELHLCETNVLNDLTEFDSHCSATLVAVATLRPGANDHL--RKEFRSKAKQLAQL-SDPNVARLVGACL-RDEP--ICIVQDYSHCLG
... .|||.| ||| .... .        |     . ||| .|..|| ..   |..| . || . || . ||. ||.|.|. ..||  |.||  |  ..|
ITFGKKLGEGAFGEVYKGTWKG-------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYM-PHG

DLNQFLQEHVAETSGLMAKKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVC
||  .|..|       . |..|.   |. ...|||.|| .||..|..|||||.| | .. ...||.|
DLLDYLRKHR------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKIC
Kinase CG11573.AA TK-Unique 699-804 42 5.9e-32 107.54 In-house 193-294 (294) Show / Hide 
Range on Protein: 699-804
Range on HMM: 193-294/294
Sequence Identity: 42% (47 aa)

RQSQPMPIRWMAWESVL--LGKF-TTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNC-PREIYDLMCECWQRDESSR
......|||||| || .   | . |||||||||.| .|||.|.   .||  ...|...|.|   ||       .| |..| ..|.| || .|||.....|
CSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGA-CPYPGMPWKDIMECIRDGYR-------MPQPEHCCSHEMYNLMKSCWQWEPEER

PSFREIHLYL
||||.|   |
PSFRQIKHRL
Kinase CG11573.AA Src 697-804 37 1.1e-30 101.48 In-house 155-255 (255) Show / Hide 
Range on Protein: 697-804
Range on HMM: 155-255/255
Sequence Identity: 37% (41 aa)

TGRQSQPMPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYD-LMCECWQRDESSRP
. |.   .||.|.| | .. |.||.||||||| . |.|| |. |  ||.  . . |....   ||       .|.|.||| |.|. .|..||..|   ||
CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGR-VPYPGMTNHEVLQQVERGYR-------MPCPHNCPDELYEQIMLQCWHKDPEQRP

SFREIHLYL
 |  .. .|
TFEYLQWFL
Kinase CG11573.AA TK-Unique 515-675 24 1.1e-27 92.54 In-house 1-175 (294) Show / Hide 
Range on Protein: 515-675
Range on HMM: 1-175/294
Sequence Identity: 24% (44 aa)

LVIVEKLGSGVFGELHLCETNVLNDLTEFDSHCSATLVAVATLRPGANDHLRKEFRSKAKQLAQLS-DPNVARLVGACLRD-EPICIVQDYSHCLGDLNQ
|.. ...|.| ||. . .|   ..      ...  . ||| .|. .|.|. ...| ...... .|   ||. ...|.| .. || .|.  | .| |.|  
LEVGDVIGEGAFGQVWRGEVWGIW-----KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPC-GNLQH

FLQEHVAETSGL-------------MAKKS---LSFGCLVYIATQIASGMKHLEQ--MNFVHRDLATRSCIIGPELCVKVC
.|..   ....               .|..   .| . |. .| |||.||..|..  ...|||||..| . ..  . .|.|
YLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKIC
Kinase CG11573.AA Src 550-675 33 1.6e-21 69.85 In-house 24-139 (255) Show / Hide 
Range on Protein: 550-675
Range on HMM: 24-139/255
Sequence Identity: 33% (42 aa)

TLVAVATLRPGANDHLRKEFRSKAKQLAQLSDPNVARLVGACLRDEPICIVQDYSHCLGDLNQFLQEHVAETSGLMAKKSLSFGCLVYIATQIASGMKHL
| ||| ||.||      . |   |. . .|. ... .|   | ..||| ||. |  . | | ..|..           ..|..  |...|.|.|.||. |
TKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEY-MSHGSLLDYLKK-------DGEGRHLHLPQLIDMAAQVAEGMAYL

EQMNFVHRDLATRSCIIGPELCVKVC
|.||..||||| |   .| ....||.
ESMNYIHRDLAARNVLVGENNVCKVA
Kinase CG11573.AA S_TKc 515-804 16 8.7e-15 39.93 SMART 1-231 (231) Show / Hide 
Range on Protein: 515-804
Range on HMM: 1-231/231
Sequence Identity: 16% (51 aa)

LVIVEKLGSGVFGELHLCETNVLNDLTEFDSHCSATLVAVATLRPGANDHLRKEFRSKAKQLAQLSDPNVARLVGACLRDEPICIVQDYSHC-LGDLNQF
  |..|.|.| ||. ..|  .            .  .||.  ..    .|.|.| .   |       ||. .| ...   . ...| .|    |||| ..
YEILRKIGKGAFGKVYKCRHKK-----------TGRIVAIKIIK----EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY

LQEHVAETSGLMAKKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVC--SIGTVINRSAYASDYCQLEGFTGRQSQPMPIRWMAW
....  .      .. ..     ... ||....... .....||||      .    ..|.|   . ...                   ..     .|| 
IKKRGRHG----LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFCGTPWYMAP

ESVLLGKFTT-KSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHL--------
| .   .... |.|.||. . |.| |.  .. |..   .. ....||                  ..|  |... |.|.| . ||.  |.          
EVL---GYGKCKCDWWSCGCILYEMLC--GYPPFP--QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

-YL
 ..
PWF
Kinase CG11573.AA CTKA 515-596 28 1.5e-10 31.51 In-house 1-83 (290) Show / Hide 
Range on Protein: 515-596
Range on HMM: 1-83/290
Sequence Identity: 28% (24 aa)

LVIVEKLGSGVFGELHLCETNVLNDLTEFDSHCSA-TLVAVATLRPGANDHLRKEFRSKAKQLA--QLSDPNVARLVGACLRDEP
. |  |.|.| .|.    .     |  .|       ..|||  |.  |..  |..|   |  |.  ... ||| ||.| |....|
HCIMFKIGEGHYGQVF--RAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKP
Kinase CG11573.AA Pkinase 720-804 17 7.3e-09 32.43 Pfam 190-293 (293) Show / Hide 
Range on Protein: 720-804
Range on HMM: 190-293/293
Sequence Identity: 17% (19 aa)

TTKSDVWSFAVALWEILTFAREQPYEHL------SDKSVIENIGL---IYRDYKMHELL-----------PMPPNCPREIYDLMCECWQRDESSRPSFRE
..|.|.||. . |.| |.  .. |. .       ... .|..|.     .  .. ..             .  .| ..|  |... |...| ..||....
GPKVDMWSCGCILYEMLC--GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQ

I--HLYL
|  | ..
ILQHPWF
Kinase CG11573.AA Pkinase 582-659 23 5.3e-05 18.76 Pfam 60-134 (293) Show / Hide 
Range on Protein: 582-659
Range on HMM: 60-134/293
Sequence Identity: 23% (20 aa)

PNVARLVGACLRDEPICIVQDYSHCLG-----DLNQFLQEHVAETSGLMAKKSL--SFGCLVYIATQIASGMKHLEQMNFVHRDL
||. || ... ..  |..|..|  | |     ||  ...         ......  |   .  ...||..|.... .|...||||
PNIVRLYDWFEDKDHIYMVMEY--CEGGLYVMDLFDYIST--------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDL
Kinase CG11573.AA Src 515-528 50 0.002747 6.97 In-house 1-14 (255) Show / Hide 
Range on Protein: 515-528
Range on HMM: 1-14/255
Sequence Identity: 50% (7 aa)

LVIVEKLGSGVFGE
.  ..|||.| |||
IKLCRKLGQGQFGE
Kinase CG11573.AA Pkinase 515-528 50 0.514749 4.67 Pfam 1-14 (293) Show / Hide 
Range on Protein: 515-528
Range on HMM: 1-14/293
Sequence Identity: 50% (7 aa)

LVIVEKLGSGVFGE
..|..|.||| ||.
YHIGRKIGSGSFGC