Gene dco (Fruit Fly)

dco

Species: Fruit Fly
Alias: l(3)discs overgrown-1, l(3)dco-1, 0915/10, l(3)S144701, l(3)discs overgrown, double-time, dbt, l(3)rK215, 0538/13, DCO/CKIe, doubletime, 1396/02, dco-1, 1460/09, dco, l(3)dco, 1447/01, SFO215, l(3)S053813, CG2048, Double-time, l(3)j3B9
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 100B2,

Classification

Group: CK1
Family: CK1
Subfamily: CK1-D

Sequence

Name Sequence Type Origin Length Description Download
dco.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 265 Kinase domain by global Sugen HMM Fasta, JSON
dco.AA Protein Various 440 None Fasta, JSON

Protein domain

Protein domains of dco.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase dco.AA CK1 9-267 70 1e-207 696.37 In-house 1-271 (271) Show / Hide 
Range on Protein: 9-267
Range on HMM: 1-271/271
Sequence Identity: 70% (190 aa)

YRLGRKIGSGSFGDIYLGTTINTGEE--VAIKLECIRTKHPQLHIESKFYKTMQG------GIGIPRIIWCGSE--GDYNVMVMELLGPSLEDLFNFCSR
||.|||||.|||||||||. ...|||  ||||||....||||||.|.|.|| .||      ..|||...||| |  ||||.|||.|||||||||||||.|
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCNR

RFSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGL-GKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDLE
.|||||||..|||||.|| |.|...||||||||||||||. ||... ||||||||||..||... .||||||||||||||||||||||||||||||||.|
KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDME

SLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKG-FPSEFVNYLNFCRQMHFDQRPDYC
|||||||||. | ||||||||..|.||||.|.|||.||.. .|||| ||.||..|||.|||.||...|||.
SLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase dco.AA CK1-D 9-269 82 4e-206 691.07 In-house 1-261 (261) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-261/261
Sequence Identity: 82% (215 aa)

YRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLL
||.|||||||||||||.||.|.|.||||||||||.||||||||||||||.||||||||.| |||.|||||||||.|||||||||||.|.|.|||||||.|
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLML

ADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNL
|||||.||.|||.|.|||||||||||||||||.||.||||||||||..||||. .||||||||||||||||||||||.|||||||||||||||||||||.
ADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNR

GALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHL
|.|||||||||.||||||||.|||.||.| .||||.||||..|.|.||...||..||||.|
GSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase dco.AA CK1-Unclassified 9-241 65 1.8e-192 573.31 In-house 1-244 (244) Show / Hide 
Range on Protein: 9-241
Range on HMM: 1-244/244
Sequence Identity: 65% (160 aa)

YRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGI-------GIPRIIWCGSE--GDYNVMVMELLGPSLEDLFNFCSRR
||...|||.||||.||... ..|.||||||||   .||||| .| |... .|.|        |||...||| |  ||||.|||.|||||||||||.| |.
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK

FSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMG-LGKKGNLVYIIDFGLAKKFRDA-RSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDLE
|||||||..|||||.|| |.|.. |||||||||||||| |||. . ||||||||.|...|. .  |||||||||||||||||||||.|||||||||||||
FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLE

SLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLC
||||||.||  | ||||..|| || .|||.| |.|.||..  ||
SLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase dco.AA CK1-A 9-269 69 1.8e-170 572.59 In-house 1-261 (261) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-261/261
Sequence Identity: 69% (182 aa)

YRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLL
||| |||||||||||||| .|. |||||||.|  . .||||  |.| |. .||..|||.. | |.| |||||||.|||||||||||||.|||..||||.|
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLML

ADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNL
|||||.||.|.| . ||||||||||||||.|.  | ...||||||||.||.|. .|||||| ||||||||||||| |||||||||||.||.|||.||||.
ADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNR

GALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHL
| |||||.||..|.||||.|||||.||.| .||||||.||  |.|.||.. |.. ||| .|
GKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase dco.AA CK1-G 9-269 53 1.9e-143 482.87 In-house 1-266 (266) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-266/266
Sequence Identity: 53% (141 aa)

YRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGI-GIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLL
|| |.||| |.|| ...|. . ..| ||||.| .... |||| | .||| . |   |||.. . | .| ||.|||.||||||||||..| |.||.|||..
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM

LADQMISRIDYIHSRDFIHRDIKPDNFLMGL--GKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMY
.| |||.|. |.||.. | ||.|||||| |    |. ....|||||.||...| .  .|||||| | ||||||| ||||||| |||||||.|.|| . ||
VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY

FNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKG--FPSEFVNYLNFCRQMHFDQRPDYCHL
|  | |||||||| | ...|..| ..| .| | .||..  || .|  || . |.. |.  ||| .|
FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase dco.AA CK1 9-269 37 5.8e-137 461.31 In-house 1-339 (339) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-339/339
Sequence Identity: 37% (129 aa)

YRLGRKIGSGSFG-DIYLG-----TTINTG-----EEVAIKLECIRTK--HPQLHIESKFYKTMQGG-------------------IGIPRIIWCGSEGD
.....|||.|.|| .||..     . ....     ||.|.|.| . ..  ||||..|...|| .|||                   ...|...|.. |.|
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--YNVMVMELLGPSLEDLFN---FCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGL------GKKGN--------LVYIIDFGLAK-KF
  ||.|||.||||.||||..   .| |.||.||.| .|.||.... |.|.. |||||||||||.||.      ||. .         ||.||||.|. |.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY

RDA-----------RSLKHIPYRE---NKNLTG-TARYASINTHLGIEQSRRDDLESLGYVLMYFNLGA--LPWQGLKAANK-------RQKYERISEKK
||            .  .|.|.||   .|...| ||||.|||.|||.||.|||||.|..|.|.... |   ||||..|. .|       ..||| |.|||
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK

LSTSIVVLCKG-----FPSEFVNYLNFCRQMHFDQRPDYCHL
.||..  ||..     .|.||  ... .|.. .. ||||  .
MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase dco.AA TTBKL 9-273 27 5.3e-58 194.42 In-house 1-288 (288) Show / Hide 
Range on Protein: 9-273
Range on HMM: 1-288/288
Sequence Identity: 27% (81 aa)

YRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRT-KHPQ--LHIESKFYKTMQ--GGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLF--NFCSRRFS
..  ..||.| || .|..  ... ...|.. |  ..  .    ...| .  . .|  | . .|.....| ..||| |||.|.||.| ||   . . .|||
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

LKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKK----GNLVYIIDFGLAKKFRDARS----------LKHIPYRE---NKNLTGTARYASINT
  |.. .. | .  . ..|.  |||||.|| |. .|. ..      .||.||||.|.....  .          ... . |.      . || ||.|.| 
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKG------FPSEFVNYLNFCRQMHFDQRPDYCHLRKLF
|.. ||.| ||| |. |.......| |||.... .      ..| ..|....  .|.|.      .||||       |.. . .||||  ....|
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase dco.AA TTBK 9-269 37 3.2e-56 193.11 In-house 1-257 (257) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-257/257
Sequence Identity: 37% (100 aa)

YRLGRKIGSGSFGDIYLGTTINTG-EEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSR-RFSLKTVL
 .  .||| | || || .. . .  |.||||.|  ...   | .|    | .||   . | | || . ..| |||.|.| .| ||    .|  ||| | |
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

LLADQMISRIDYIHSRDFIHRDIKPDNFLMG-LGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMY
 |  |..  |  |||  | |||||| || || . .. . .|..||||| ..  |      | ||     ||.|||||| |.  |  |.||| || |.|  
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPP-REVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVE

FNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHL
|  | |||  .|        . . | |     ..| |  |.||  ...  . . .  ||||  .
FVQGQLPWRKIKDK------DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase dco.AA Worm6 9-269 28 6.8e-52 178.72 In-house 1-279 (279) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-279/279
Sequence Identity: 28% (79 aa)

YRLGRKIGSGSFGDIYLGTTINTGE--EVAIKLEC--IRTKHPQLHIESKFYKTM--QGGIGIPRIIWCGSEGD--YNVMVMELLGPSLEDLFNFC-SRR
. ...|||.|.||..|. .   ...  ..|.|.|      |...| .|    |.   ... . ..|. .|  .   .| .||.|.|..|.||  ..  |.
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGL-----GKKGNLVYIIDFGLAK-KFRDARSLKHIPYR-ENKNLTGTARYASINTHLGIEQSR
||. | | .| |.. .|   |.  |||||.|| ||  |       ..   .|..|||... |. . .  . .. | ..    || |||... | |.||.|
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCR

RDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKG-FPS-EFVNYLNFCRQMHFDQRPDYCHL
.||.||  |..  . .| |||...|. .  .|. .   ....  .  .  | .|  ||.  .    |. .  |||| ..
KDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase dco.AA Pkinase 9-251 25 9.5e-45 159.31 Pfam 1-252 (293) Show / Hide 
Range on Protein: 9-251
Range on HMM: 1-252/293
Sequence Identity: 25% (67 aa)

YRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHI------ESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFC------
|..||||||||||  |... ..||..||.|  . |..... ..      | .  | ..    .  . |. . .|.  ||||...  |. ..  .      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLY-VMDLFDYISTW

-SRRF--SLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKKGNL---VYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHL-GIE
 ...|  | ...   . |... ..|.||. .||||.||.|.|.   ..|..   | |.||||||.|.      . ... .. ..|| .|..   .. | .
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQY

QSRRDDLESLGYVLMYFNLGALPWQGL----KAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNY
 ... |  |.| .| .. .| .|..|     . ....|...|| ...|. ..  .| . ... ...
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH
Kinase dco.AA VRK 80-213 39 4.8e-26 80.75 In-house 106-240 (284) Show / Hide 
Range on Protein: 80-213
Range on HMM: 106-240/284
Sequence Identity: 39% (54 aa)

MVMELLGPSLEDLFN-FCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLT--GT
|||. .| .|. .    .  ||| |||| || .|.    |.|. .  | |||  | | |. |  . || .|.||| .. .    || .| |..     ||
MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCPNG--KHRQYKEDPRRCHNGT

ARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPW
  . |.  |.|   ||| |||.||| .|.   | |||
CEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPW
Kinase dco.AA S_TKc 9-273 22 4e-16 59.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-273
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

YRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRR--------F
|...||||.|.||  |... ..||..||||         ..  | .  |   .   | ... .  . |.  ||||... .| ||| .  .|        |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSR-RDDLESL
.  ..  .. |... ..|.||. .||||.||.| |.        . |.|||||...              . . ||  | .         .. . |  |.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHLRK---------LF
| .|  .  |  |..     .  . ...|                ..|. . .. | |.  ..||    . .          |
GCILYEMLCGYPPFP-----QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase dco.AA TyrKc 9-273 18 2.5e-08 -88.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-273
Range on HMM: 1-280/280
Sequence Identity: 18% (56 aa)

YRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTM-QGGIGIPRIIWCGSEG-------DYNVMVMELLGP-SLEDLFNFCSRR
 .||.|.|.| || .|.|| .   ..||.|     . .  .. | .  .        | |.. . ...       .   .|||.    .| |    . ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

FSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDA------RSLKHIPYRENKNLTGTARYASINTHLGIEQSRR
...|. |  . |  .  .|.||. .||||.   | | | ..    | | ||||...  |        . ..   .....     |  ..           
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP-----------

DDLESL-GY------------VLMY--FNLGALPWQGLKA--ANKRQKYERISEKKLSTSIVVLCKG-----FPSEFVNYLNFCRQMHFDQRPDYCHLRK
   |..  .            |.|.  | .|. |. |      . .. .|.. . .        .        |.|  .    | .   ..||    ...
---ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

LF
.|
CF
Kinase dco.AA Pkinase_Tyr 9-38 41 4.9e-07 24.44 Pfam 1-34 (270) Show / Hide 
Range on Protein: 9-38
Range on HMM: 1-34/270
Sequence Identity: 41% (14 aa)

YRLGRKIGSGSFGDIYLGTTI----NTGEEVAIK
 ..|.|.|.|.||..|.||      ||. .||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK
Kinase dco.AA VRK 9-25 64 9e-06 14.87 In-house 1-17 (284) Show / Hide 
Range on Protein: 9-25
Range on HMM: 1-17/284
Sequence Identity: 64% (11 aa)

YRLGRKIGSGSFGDIYL
.|||..||.| || |||
WRLGKPIGQGGFGCIYL
Kinase dco.AA Pkinase_Tyr 117-129 46 4.3831 0.91 Pfam 125-137 (270) Show / Hide 
Range on Protein: 117-129
Range on HMM: 125-137/270
Sequence Identity: 46% (6 aa)

DYIHSRDFIHRDI
.| .|. .||||.
EYLESKNCIHRDL