Gene CkIalpha (Fruit Fly)

CkIalpha

Species: Fruit Fly
Alias: CKIa, dmckI, CG2028, dmCK1, CkIalpha, Casein kinase 1, SFO076, CK I
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 11B11,

Classification

Group: CK1
Family: CK1
Subfamily: CK1-A

Sequence

Name Sequence Type Origin Length Description Download
CkIalpha.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 279 Kinase domain by global Sugen HMM Fasta, JSON
CkIalpha.AA Protein Various 337 None Fasta, JSON

Protein domain

Protein domains of CkIalpha.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CkIalpha.AA CK1-A 20-280 82 1.8e-204 685.59 In-house 1-261 (261) Show / Hide 
Range on Protein: 20-280
Range on HMM: 1-261/261
Sequence Identity: 82% (216 aa)

YRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLML
||..||||||||||||||..|..||||||||||..||||||.||||.||||.|.||.|..|..|.||..|..||||||||||||||||.|.||.||||||
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLML

VDQMIGRLEYIHLKCFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVMMYFNR
.||||.|.||.| |.||||||||||||||||||||||||||||||||.||..||.||.||||||||||||||||||||||||||||||||.|||||||||
ADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNR

GVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLRFEEQPDYMYL
|.||||||||.||.||||||||||||||||.||||.||||.||.||||.||||||||||||
GKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase CkIalpha.AA CK1 20-278 69 1.9e-203 682.19 In-house 1-271 (271) Show / Hide 
Range on Protein: 20-278
Range on HMM: 1-271/271
Sequence Identity: 69% (187 aa)

YRVIRKIGSGSFGDIYLGMSIQSGEE--VAIKMESAHARHPQLLYEAKLYRILSG------GVGFPRIRHHGKE--KNFNTLVMDLLGPSLEDLFNFCTR
|||.||||.|||||||||. ...|||  ||||.|.....||||.||||.|.|| |      ..|.|.... |.|  ...| .|||||||||||||||| |
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCNR

HFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGI-GRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDME
.|..|||||..|||| |.||.| |.||||||||||||||. |.||.....|||||||..||. |. || |||.|||||||||||||.|||||||||||||
KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDME

SLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKG-SPAEFSMYLNYCRSLRFEEQPDYM
|||||.|||.|| |||||.|||||.||||||.|||||||.|.||||  |.|| |||||||.|.|||.||||
SLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase CkIalpha.AA CK1-Unclassified 20-252 61 7.1e-185 550.53 In-house 1-244 (244) Show / Hide 
Range on Protein: 20-252
Range on HMM: 1-244/244
Sequence Identity: 61% (151 aa)

YRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGV-------GFPRIRHHGKE--KNFNTLVMDLLGPSLEDLFNFCTRH
||||.|||.||||.||... .|..||||||.|.. ..||||.||||....| .|        |.|.. . |.|   ..| .||||||||||||||.| | 
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK

FTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKFRDP-HTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDME
|..|||||..|||| |.||.| |.||||||||||||||  |.. .....|||||.|...|.  |  || |||.|||||||||||||||||||||||||.|
FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLE

SLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLC
|||||..|| .| ||||. |||.|..||||| |.|||||.| ||
SLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase CkIalpha.AA CK1-D 20-280 68 7.4e-172 577.22 In-house 1-261 (261) Show / Hide 
Range on Protein: 20-280
Range on HMM: 1-261/261
Sequence Identity: 68% (178 aa)

YRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLML
||. ||||||||||||.|  ||..||||||.|.....|||| .|.|.|....||.| |.||  |.| ..| .||||||||||||||.| |.| .||||||
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLML

VDQMIGRLEYIHLKCFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVMMYFNR
 |||| |.|||| . ||||||||||||||.|.. |  ..|||||||..||..|..|| |||.||||||||||||| |.|||||||||.||||||.|||||
ADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNR

GVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLRFEEQPDYMYL
| |||||.|| ||.||||.|.||||||.|..|||| | ||. |.||||.|.|...|||.||
GSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase CkIalpha.AA CK1-G 20-280 52 1.4e-135 456.73 In-house 1-266 (266) Show / Hide 
Range on Protein: 20-280
Range on HMM: 1-266/266
Sequence Identity: 52% (140 aa)

YRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGV-GFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLM
||| .||| |.|| ...|  .  .| ||||.|  . | |||  | . |.||.| . | |..   | .  .| .|||||||||||||..| |.|..|||.|
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM

LVDQMIGRLEYIHLKCFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVMMY
.  ||| |.||.| .  | ||.|||||| |    .. .....||||.||...||.|. || ||| | ||||||| ||| ||| |||||||||.|| . ||
VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY

FNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKG--SPAEFSMYLNYCRSLRFEEQPDYMYL
| || |||||.|| .  ..|.|| ..| .|.||.||..   | .|  || | |.| |.|.||| ||
FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase CkIalpha.AA CK1 20-280 36 1.9e-135 456.26 In-house 1-339 (339) Show / Hide 
Range on Protein: 20-280
Range on HMM: 1-339/339
Sequence Identity: 36% (126 aa)

YRVIRKIGSGSFG-DIYLG-----MSIQSG-----EEVAIKMESAHAR--HPQLLYEAKLYRILSGG-------------------VGFPRIRHHGKEKN
..|..|||.|.|| .||..     ......     ||.|.|.|.....  ||||..|...|..| ||                   ...|.... ..|..
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--FNTLVMDLLGPSLEDLFN---FCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGI------GRHCN--------KLFLIDFGLAK-KF
  .| .||.||||.||||..   .|.|.|. ||.||. .||. .|||.| ..|||||||||||.||.      |.| .        ....||||.|. |.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY

RDPHTRH-----------HIVYRE---DKNLTG-TARYASINAHLGIEQSRRDDMESLGYVMMYFNRGV--LPWQGMKANTK-------QQKYEKISEKK
||..  .           |. .||    |...| ||||.|||.|||.||.||||..|..|.......|   ||||.||...|       ..|||.|.|||
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK

MSTPIEVLCKG-----SPAEFSMYLNYCRSLRFEEQPDYMYL
||||.. ||..     .| || ....|.|||.... |||...
MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase CkIalpha.AA TTBKL 20-284 28 1.1e-56 189.95 In-house 1-288 (288) Show / Hide 
Range on Protein: 20-284
Range on HMM: 1-288/288
Sequence Identity: 28% (85 aa)

YRVIRKIGSGSFGDIYLGMSIQS-GEEVAIKMESAH-ARHPQLL-YEAKLYRILS--GGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRH--FT
......||.| || .|....... ... | |.|.   .. .. .  |...   |.  |   ||..   ||.|..| .|| |.||.| || .   .   |.
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

IKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGIGRH----CNKLFLIDFGLAKKFRDPHT-------RHHIVYREDKN------LTGTARYASINA
  |.. .  | .  | ..| ..|||||.|| |. .|.  |    |  ..|||||.|.......        .     |. .|      . || ||.|.|.
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKG------SPAEFSMYLNYCRSLRFEEQPDYMYLRQLF
|.. ||.| ||. |. |...... | |||..|.        ..| ..|...  |.|.|.      .| || .   . ||||. ..|||......|
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase CkIalpha.AA Worm6 20-280 27 2.3e-53 183.61 In-house 1-279 (279) Show / Hide 
Range on Protein: 20-280
Range on HMM: 1-279/279
Sequence Identity: 27% (79 aa)

YRVIRKIGSGSFGDIYLGMSIQSGE--EVAIKMES--AHARHPQLLYEAKLYRIL--SGGVGFPRIRHHGKEKN--FNTLVMDLLGPSLEDLFNFC-TRH
. | .|||.|.||..|.    . ..  ..|.| |.  . . ...|  |.     .  ... .|..|  .|| .|  || .|| |.|..|.||  .. .|.
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGI-----GRHCNKLFLIDFGLAK--KFRDPHT-----R-HHIVYREDKNLTGTARYASINAHL
|.  | | .  |.. ..|  |   |||||.|| ||  |       .   .....|||...  |...  .     | ... .|      || |||....| 
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFR------GTVRYAPLACHK

GIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQ-KYEKISEKKMSTPIEVLCKGSPA-EFSMYLNYCRSLRFEEQPDYMYL
|.||.|.||.||  |.|  . .| |||..||.   ..  ....  .. ..  . . .. |. ||.  . |  ...... ||| ..
GQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase CkIalpha.AA TTBK 20-280 36 4.8e-49 169.25 In-house 1-257 (257) Show / Hide 
Range on Protein: 20-280
Range on HMM: 1-257/257
Sequence Identity: 36% (97 aa)

YRVIRKIGSGSFGDIYLGMSIQSG-EEVAIKMESAHARHPQLLYEAKLYRILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTR-HFTIKTVL
 .|..||| | || || .. ..   |.||||.|||..    |  |    . | |     |    | . .|| .||.|.| .| ||     |  |.. | |
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

MLVDQMIGRLEYIHLKCFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVMMY
 |  |..  .| ||   | |||||| || ||     |.| ...||||| ..   .       ||     ||.||||||||.  |  |.||. || |..  
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPP-REVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVE

FNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLRFEEQPDYMYL
|  | |||  .|        ... | |      .| |  | ||.....  .|| .|..|||  .
FVQGQLPWRKIKDK------DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase CkIalpha.AA Pkinase 20-271 20 6.6e-31 110.36 Pfam 1-258 (293) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-258/293
Sequence Identity: 20% (57 aa)

YRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLY------EAKLYRILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFC------
|...|||||||||  |... . .|..||.|  . . .... ..      |... . |.       ..    ...   .||....  |. ..  .      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLY-VMDLFDYISTW

-TRHF--TIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHL-GIEQS
  . |  . ... . . |..  |||.| . .||||.||.|.|.   |  . .. ..||||||.|.      .  ..  . ..|| .|..   .. | . .
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

RRDDMESLGYVMMYFNRGVLPWQGM----KANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLRF
.. || |.| .. ..  | .|..|     . ....|....| ... . ... .| .|. .  ..   .. ...
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWT
Kinase CkIalpha.AA VRK 91-243 35 2.5e-23 71.96 In-house 106-256 (284) Show / Hide 
Range on Protein: 91-243
Range on HMM: 106-256/284
Sequence Identity: 35% (56 aa)

LVMDLLGPSLEDLFN-FCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTR-HHIVYREDKNLT--G
.||. .| .|. .    .   |. |||| |  .|.  |||.| .   | |||  | | |     .. .|.|.||| .. .   .  | .| ||.     |
MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCP---NGKHRQYKEDPRRCHNG

TARYASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKK
|  . |. ||.|   ||| | |.||| ||.   | |||   ... .||  ||.   |
TCEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPW---MDCLQQQDPEKVQDAK
Kinase CkIalpha.AA S_TKc 20-296 18 1.5e-14 36.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-296
Range on HMM: 1-231/231
Sequence Identity: 18% (54 aa)

YRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRH--------F
|...||||.|.||  |..  . .|..||||. .      ... | .. .   .     ..  .  . ..  .||.... .| ||| .  ..        |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSR-RDDMESL
.  ..  .. |..  |||.| . .||||.||.| |.        . ..|||||...              . . ||  | .         .. . |. |.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLRFEEQPDYMYLRQLFRI-------LFRTLN-------HQYD
| ..  .  |  |..     . |. ..||                                  ..    .|....            |.       |.. 
GCILYEMLCGYPPFP-----QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CkIalpha.AA Pkinase_Tyr 20-66 30 3e-06 21.96 Pfam 1-56 (270) Show / Hide 
Range on Protein: 20-66
Range on HMM: 1-56/270
Sequence Identity: 30% (17 aa)

YRVIRKIGSGSFGDIYLGMSI----QSGEEVAIKMESAHARHPQ-----LLYEAKL
 . ..|.|.|.||..|.|       . . .||.||   .| |.|     .. |||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKI
Kinase CkIalpha.AA TyrKc 20-284 16 5e-06 -125.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-284
Range on HMM: 1-280/280
Sequence Identity: 16% (56 aa)

YRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRIL---------SGGVGFPR-------------------------IRHHGKE
 . ..|.|.| || .|.|. .   ..||.||  ..| .  .. ||.. . |           ||                             .| |...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

KNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGIGRHCNKLFLI---DFGLAKKFRDPHTRH------HI
                         .. |. |    |     ||.| |..||||.   | | | ..       .   ||||...    .. .      . 
-------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRD----IYDDDQQGESKD

VYREDK--NLT--GTARYASINAHLGIEQSRRDDMESL-GY------------VMMY--FNRGVLPWQGMKA--NTKQQKYEKISEKKMSTPIEVLCKG-
.||  .  .       |  ..              |..  .            |.|.  | .|  |. ||     . |. .|.. . ..  . .  .   
YYRKKEHKGGKTMLPIRWMAP--------------ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PM

----SPAEFSMYLNYCRSLRFEEQPDYMYLRQLF
     |.|  .    |     |. |    ....|
SFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CkIalpha.AA VRK 20-36 52 0.005545 5.89 In-house 1-17 (284) Show / Hide 
Range on Protein: 20-36
Range on HMM: 1-17/284
Sequence Identity: 52% (9 aa)

YRVIRKIGSGSFGDIYL
.|. ..||.| || |||
WRLGKPIGQGGFGCIYL
Kinase CkIalpha.AA Pkinase_Tyr 127-140 50 2.25143 1.89 Pfam 124-137 (270) Show / Hide 
Range on Protein: 127-140
Range on HMM: 124-137/270
Sequence Identity: 50% (7 aa)

LEYIHLKCFIHRDI
.|| . | .||||.
MEYLESKNCIHRDL