Gene gish (Fruit Fly)

gish

Species: Fruit Fly
Alias: CKI-related, SFO050, ms(3)89B, CG6963, Hrr25, CKIg-like, gish, gilgamesh, CKIgamma
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 89B16--17,

Classification

Group: CK1
Family: CK1
Subfamily: CK1-G

Sequence

Name Sequence Type Origin Length Description Download
gish.AA Protein Various 422 None Fasta, JSON
gish.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 283 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of gish.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase gish.AA CK1-G 21-284 77 3.6e-227 760.98 In-house 1-266 (266) Show / Hide 
Range on Protein: 21-284
Range on HMM: 1-266/266
Sequence Identity: 77% (207 aa)

FRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHAEGVPEVYYFGPCGKYNALVMELLGPSLEDLFDICGRRFTLKSVLL
.||||||||||||||..|||.|||||||||.|||||.|||||.||||||.|....||.|.|||||.|||||..||.|||||||||||.|.|.|..|.|..
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM

IAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMY
.|||..||.|||||.|||||||||.||||||.|.|....|||||||.||.|||..|..||||||||||||||||||||||.|||||||||.|||||||||
VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY

FLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDG--HPEEFATYLRYVRRLDFFETPDYDFL
||||||||||||||..||||||||||||.|.||.||..  .||.|||||||||||||||.||||.|
FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase gish.AA CK1 21-282 57 1.6e-188 632.6 In-house 1-271 (271) Show / Hide 
Range on Protein: 21-282
Range on HMM: 1-271/271
Sequence Identity: 57% (157 aa)

FRVGKKIGCGNFGELRLGKNLYNNEH---VAIKMEPMKSKAPQLHLEYRFYKLLGS-----HAEGVPEVYYFGPC--GKYNALVMELLGPSLEDLFDICG
.|||.|||.|.||...||.|. .|..   ||||.|..|||.|||| |...|| |       ...|.| .|..|..  |.||..||.||||||||||..|.
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCN

RRFTLKSVLLIAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDD
|.|.|| ||.|| |...||||||....|.||.||.|||.|| . |......||||||||.|.| .|..||||||.|.|||||||.|||||.|.|||||||
RKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR-YGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD

LEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDG-HPEEFATYLRYVRRLDFFETPDYD
.|.||...|||||||||||||||.| |..|.||...|. ||.|.|| | .|.|||.||.|.|.|.|.|.|||.
MESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase gish.AA CK1-Unclassified 21-256 53 8.10000000001e-151 448.32 In-house 1-244 (244) Show / Hide 
Range on Protein: 21-256
Range on HMM: 1-244/244
Sequence Identity: 53% (131 aa)

FRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHA------EGVPEVYYFGPC--GKYNALVMELLGPSLEDLFDICGRR
.||..|||.| |||  ...|. .||.||||.|  .|| |||  | .... |  ..       |.| .|..|    | || .||.|||||||||| .|.|.
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK

FTLKSVLLIAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDL-DTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDL
|.|| ||.|| |.. ||||.|....|.|| ||.|||.|. . |. ....||||||.| |||   |..|||||| |.||||||| |||.| | ||||||||
FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGK-LGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDL

EALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLC
|.||  ..|||.||||||..||.. ||.|.|| . |  ||.| ||
ESLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase gish.AA CK1-D 21-284 56 8.49999999999e-135 454.12 In-house 1-261 (261) Show / Hide 
Range on Protein: 21-284
Range on HMM: 1-261/261
Sequence Identity: 56% (149 aa)

FRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHAEGVPEVYYFGPCGKYNALVMELLGPSLEDLFDICGRRFTLKSVLL
.|.|.||| | ||.. .|.|. .|| ||||.|..|.| ||||.| .|||.. .   |.||. ..|  | ||..||.||||||||||  |.|.| || ||.
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMM-QGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLM

IAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMY
.| |.. ||||.|.|  | ||.||.|||.|    || ....|||||||| | |  | .||||||.|.||||||| |||||.| |||||||||.|| ..||
LADQMICRIEYIHCRNFIHRDIKPDNFLMGL--GKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMY

FLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFL
| ||||||||||| | ...|..| . |  |.|..||.|.|.||..|. |.|.| | . ||| .|
FNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase gish.AA CK1 21-284 34 1.1e-122 413.89 In-house 1-339 (339) Show / Hide 
Range on Protein: 21-284
Range on HMM: 1-339/339
Sequence Identity: 34% (117 aa)

FRVGKKIGCGNFG-ELRLG-----KNLYNN-----EHVAIKMEPMKSK--APQLHLEYRFYKLLG------------------SHAEGVPEVYYFGPCGK
..|.||||.| || .  ..     |.. ||     |..|.|.|| ||.   |||. ||..||.|                   ..... | .|... ...
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--YNALVMELLGPSLEDLFD---ICGRRFTLKSVLLIAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTS-----------TKREKIIHIIDFGLAK-EYI
  || .||.||||.||||..    |.|.|..|..| ||||.| ..||.|... |.||.||.||..|| .            ........||||.|.  |.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

DLDTNR-----------HIPYRE---HKSLTG-TARYMSINTHMGREQSRRDDLEALGHMFMYFLRGS--LPWQGLKADTL-------KERYQKIGDTKR
| | ..           |.|.||   .|...| ||||.|||.| |.||.|||||.....|....|.|.  ||||..|. .        |. |..| ..| 
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

ATPIEVLCDG-----HPEEFATYLRYVRRLDFFETPDYDFL
 ||.. || .      |.|| ... |.| |.....|||...
STPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase gish.AA CK1-A 21-284 54 1.1e-115 390.59 In-house 1-261 (261) Show / Hide 
Range on Protein: 21-284
Range on HMM: 1-261/261
Sequence Identity: 54% (143 aa)

FRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHAEGVPEVYYFGPCGKYNALVMELLGPSLEDLFDICGRRFTLKSVLL
.|. .||| | ||.. || |. | | ||||||  | . |||  | . |..| . . |.|.. ..|    ||..||.|||||||||| .| ||||.| ||.
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRIL-QGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLM

IAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMY
.| |.. |||||| .  | ||.||.|||.|    .    ...||||||| | |  | .|||||| | ||||||| ||| |.| |||||||.|..| ..||
LADQMIMRIEYVHEKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMY

FLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFL
| ||.|||||.|| | | .| || . | .||||.|| | | ||. |. |.| | | |.||| .|
FNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase gish.AA TTBKL 21-288 26 1.8e-50 168.64 In-house 1-288 (288) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-288/288
Sequence Identity: 26% (78 aa)

FRVGKKIGCGNFGELRLGKNLYN-NEHVAIKMEPMK-SK-APQLHLE-YRFYKLLGSHAEGVPEVYYFGPCGKYNALVMELLGPSLEDLF-DICGRR-FT
... |.|| | ||.  ..... . ... | |.|... ..    ...| . ..||   ..  .|.... |  ..|| .||.|.||.| ||  ... .. |.
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

LKSVLLIAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTS--TKREKIIHIIDFGLAKEYIDLDTN----------RHIPYRE---HKSLTGTARYMSINT
  ... |.||.|. . ..|.   | ||||| |. .| ..  ..|......||||.|. |.. | .          .. . |.   . .. || ||.|.| 
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HMGREQSRRDDLEALGHMFMYFLRGSLPWQGLK-ADTLKERYQKIGDTKRATPIEVLCDGHP------EEFATYLRYVRRLDFFETPDYDFLRRLF
|...||.| ||| ..  |..... | |||.... ..       .|. .|...  |.|. ..|       ||.   ...|.|.. ..|||. .. .|
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKM-------EIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase gish.AA TTBK 21-284 35 9e-47 161.71 In-house 1-257 (257) Show / Hide 
Range on Protein: 21-284
Range on HMM: 1-257/257
Sequence Identity: 35% (95 aa)

FRVGKKIGCGNFGELRLGKNLYNN-EHVAIKMEPMKSKAPQLHLEYRFYKLLGSHAEGVPEVYYFGPCG---KYNALVMELLGPSLEDLFDICGR-RFTL
 .| |||| | |||   .|.. |. |.||||.|  . .   | .|    | |     | . |  |  ||   |.| .||.|.| .| ||     |  |.|
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKL----QGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSL

KSVLLIAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALG
 . | . .|.|  || .||     ||.|| || .||.. .. ... ..|||||  |.    .   | ||     ||.|| ||| |  ||  |.|||  | 
STTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTC-RKCYMLDFGLARQYTNACGEVRPP-REVAGFRGTVRYASINAHRNREMGRHDDLWSLF

HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFL
 |   |. | |||  .|    |.   ..| .|      .| .  |.|| ...  .. |.....||| ..
YMLVEFVQGQLPWRKIKD---KD---QVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase gish.AA Worm6 21-284 29 8.8e-46 158.41 In-house 1-279 (279) Show / Hide 
Range on Protein: 21-284
Range on HMM: 1-279/279
Sequence Identity: 29% (83 aa)

FRVGKKIGCGNFGELRLGKNLYNNE--HVAIKMEP--MKSKAPQLHLEYRFYKLLGSH-AEGVPEVYYFGPCGK--YNALVMELLGPSLEDLFDIC-GRR
. |.|||| | ||   . ..  ...  ..|.| |    ..| ..| .|.   |... | .......   |  ..  .| .||.|.|..|.||   . .|.
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FTLKSVLLIAIQLLHRIEYVHSRHLIYRDVKPENFLIGR---TSTKREKIIHIIDFGLAK--EYIDLDTNRHIPYR-EHKSLTGTARYMSINTHMGREQS
|..   | |||| | .|| .|. . | ||||| || |||    . . ...| ..|||...   |.. .. .. | | ..    || ||.... | |.||.
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTP-RWTACGFRGTVRYAPLACHKGQEQC

RRDDLEALGHMFMYFLRGSLPWQGLKADTLKE-RYQKIGDTKRATPIEVLCDGHPE-EFATYLRYVRRLDFFETPDYDFL
|.||.|    |   ...| |||...|..  .| .. .. ...||.  . .  . |  ||   . |.  ......|||.|.
RKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase gish.AA Pkinase 21-247 22 1.1e-35 127.27 Pfam 1-234 (293) Show / Hide 
Range on Protein: 21-247
Range on HMM: 1-234/293
Sequence Identity: 22% (56 aa)

FRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLH----L--EYRFYKLLGSHAEGVPEVYYFGPCGKYNALVMELLGPSLEDLFDIC-----
...|.||| |.||. .....  ... ||.|  . ... .. .    .  | .  | | .|   |   ..|   ...  .|||...  |. ..| .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-KDHIYMVMEYCEGGLY-VMDLFDYIST

--GRRF--TLKSVLLIAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHM-GRE
  ...|  . . .  .. |.|  .|| ||.  |.||.||||.|| .. .  . ...|.|||||| .       . ...  ....|| .||.   .. |..
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQY

QSRRDDLEALGHMFMYFLRGSLPWQGL----KADTLKERYQKIGDTK
 ... |  ..| .. ..| | .|..|     . .. ......|....
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPP
Kinase gish.AA S_TKc 21-306 20 3e-22 81.14 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-306
Range on HMM: 1-231/231
Sequence Identity: 20% (63 aa)

FRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHAEGVPEVYYFGPCGKYNALVMELLGPSLEDLFDICGRR--------
.....||| | ||. .....   ...||||. .      ..  | .  |    | . .   |..    ..  .|||... .| ||||.  .|        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK---HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FTLKSVLLIAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSR-RDDL
|.   .  .. |..  .|| ||.. |.||.|||| |. .        | |.|||||...              ... ||  ||.         .. . | 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDW

EALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQ-DLFDRKGYTDEGE-------F
 ..| ..  .| |  |..     .... ..|||                                  .  ||.|...| |  .| .  .  .        
WSCGCILYEMLCGYPPFP-----QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

DWT
 | 
PWF
Kinase gish.AA Ciliate-E2 104-196 26 8.9e-15 47.13 In-house 120-255 (365) Show / Hide 
Range on Protein: 104-196
Range on HMM: 120-255/365
Sequence Identity: 26% (39 aa)

DLFDICG-------------RRFTLKSVLLIAIQLLH---------------RIEYVHSRH-LIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDL
||||..               .||.| .. |  |.|                 .|| ||..  |.|| |||| |.          | ||||||.|.| | 
DLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------IKIIDFGLSKKYDDD

DTNRHIPYREHK-------------------------SLTGTARYMS
  || .  ...|                         .. ||. ||.
NQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMA
Kinase gish.AA TyrKc 21-288 20 2e-06 -119.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

FRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLG-SHAEGVPEVYYFGPCG------KYNALVMELLGP-SLEDLFDICGRR
 . |||.|.|.||| ..|.     . ||.||    .    .. | |  . || .|   |  . .    |      .   .|||.    .| |    ....
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

FTLKSVLLIAIQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTN--RHIPYRE--HKSLT--GTARYMSINTHMGREQS
...|  | ...|     || ||...| ||    | |.|.       .. | ||||...  | |..  ..  ||   ||.       | |..         
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP---------

RRDDLEALGHM--------FMY-------FLRGSLPWQGLKA--DTLKERYQKIGDTKRATPIEVLCDG-----HPEEFATYLRYVRRLDFFETPDYDFL
     |.. .         ...       | .|  |. |      . .| .... . .|  . .  .        |.|  .  .   . |  . |    .
-----ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

RRLF
...|
HECF
Kinase gish.AA Ciliate-E2 21-52 37 7.9e-05 12.49 In-house 1-32 (365) Show / Hide 
Range on Protein: 21-52
Range on HMM: 1-32/365
Sequence Identity: 37% (12 aa)

FRVGKKIGCGNFGELRLGKNLYNNEHVAIKME
. . |||| ||||  ...|.  ... .|||..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKII
Kinase gish.AA Pkinase_Tyr 21-51 37 0.000869 13.45 Pfam 1-35 (270) Show / Hide 
Range on Protein: 21-51
Range on HMM: 1-35/270
Sequence Identity: 37% (13 aa)

FRVGKKIGCGNFGELRLGKNL----YNNEHVAIKM
 . |||.| |.||| ..|.       .. .||.||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKM
CK1gamma_C gish.AA CK1gamma_C 308-393 31 9.6e-31 110.3 Pfam 1-121 (121) Show / Hide 
Range on Protein: 308-393
Range on HMM: 1-121/121
Sequence Identity: 31% (38 aa)

K------------TMSTPVGSLQT-GHEVIISP------NKDRHNVTAK---------TN------AKGGVAAWPDVPKPGATLGNLTPADRHGSVQVVS
|            .|.||.|.... .......|      ....|| ...         .|      .....|.|...|........|.|.|..|||||||
KIEFFSRYFFNFDQMPTPHGYIHPHPPDPSVQPRQPPNMHRQHHNHVQRYVPSMQQQQRNQTGWHRRRNWQAQWGRHPQTSYYYQQLPPQDHQGSVQVVS

STNGELN-PDDPTAGHSNTPI
|||||||  |||..||||.||
STNGELNQTDDPNTGHSNAPI