Gene Pitslre (Fruit Fly)
Pitslre
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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Pitslre.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 294 | Kinase domain by global Sugen HMM | Fasta, JSON |
Pitslre.AA | Protein | Various | 952 | None | Fasta, JSON |
Protein domains of Pitslre.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | Pitslre.AA | PITSLRE | 558-851 | 71 | 1.1e-237 | 795.91 | In-house | 1-295 (295) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-295/295 Sequence Identity: 71% (215 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKME--KEKEGFPITSLREINTLLKG-QHPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRK |||||||.|||||||||||||||.||||||||||| |||||||||||||||..|.. ||||||.|.|||.|||||||..||.|||||||||||.||.|. FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN QSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAEF |.|.|||.|||.|||||.|.|.|||||.||||||||||.|||||||..|||||||||||||.||..|||||||||||||....||||.|.|||||||||| QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF LQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQ--EKTSEMGLSLLQGLLTYDPKQRLSADAALKHGFF ..| |||.||||||..|.||||.|||.||||||.||||..|.| . |..||...|||.|. ...|..|..||...|||.||.|..|..||||..| ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNN----FPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF |
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Kinase | Pitslre.AA | CDK | 558-851 | 43 | 3.7e-171 | 552.01 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-284/284 Sequence Identity: 43% (144 aa) FQCLNRIEEGTYGVVYRAKDKRTN-----EIVALKRLKMEK-----EKEGFPITSLREINTLLKGQHPNIVTVREIVVGSNMD---------KIFIVMDY ...|..| ||||||||.|.||.|. .|||||...||. ||||||||..|||..| . |||||.........||| |...|..| YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY VEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGI-----LKVGDFGLAREYGS------PIKKYTSLVVTLWYR ..||||..|. .||...||||.....|.|||.|||||..|.|....|. ||..||||||..|. |...||. ||||||| MDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYR APELLLCSPVYS--TPIDVWSVGCIFAEFLQ---MLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQEKTSE |||||| | || ||||.|||||||||... |||||.|||| | .||. .|||.|..||| |.|| APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------- MGLSLLQGLLTYDPKQRLSADAALKHGFF ||...|.||||.|.||..||.| .| ---DLLNKMLCYDPKKRISAEQALQHPYF |
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Kinase | Pitslre.AA | CDC2 | 558-851 | 44 | 3.5e-138 | 427.55 | In-house | 1-301 (301) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-301/301 Sequence Identity: 44% (137 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEG--FPITSLREINTLLKGQ-HPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRK .|....| ||||||||..||..||.|||||. . | | || .| |..||| .| . . |||||. ..... |...| .|...||| .|. . . YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN QSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYT--SLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFA ... | || .. |.|..|...| . |.||||| .|.|.. || .|..|||||| | ||..|| ||||||||||.|| . ||||.|.||.||||| KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA EF---LQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQEK--------TSEMGLSLLQGLLTYDPKQRLS |. . |||.|.||||.| .||. ||||||..||| |.|| || | ... ..|.|.. . . . |..||. .| ||| .|.| EMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNT------FPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRIS ADAALKHGFF |..||.| .| AKEALQHPYF |
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Kinase | Pitslre.AA | CMGC | 558-851 | 26 | 3.5e-137 | 453.81 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-513/513 Sequence Identity: 26% (136 aa) FQCLNRIEEGTYGVVYRAKDKRTN--------------EIVALKRLK---MEK------EKEGFPITSLREINTLLKGQ-----------------HPNI ......| ||||||||...||||| ||||.|..| .| ||.||||..|||| | . . |.|| YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI VTVREIVVGSNMD---------------KIFIVMDYVEHDLKSLMETMKN-----RKQSFFPGE------------VKCLT------QQLLRAVA--HLH |. ..|.. .|.| ....|..|..|||. ... ... |.. . . . .|... .|.||... ..| VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH DNW--ILHRDLKTSNLLLSHK--------------------GILKVGDFGLAREYGSP---------------------IKKYTSLVVTLWYRAPELLLC .| |.||||| .|.|..|. |.||..|||||| |... . ||. |||.||||||.|| SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG SPVYS---------TPIDVWSVGCIFAEFLQM--------LPLFPGKSE-----------IDELNRIFKELGTPN---------------EKIWPGYTEL .. |. ||||.||||||||| .. |||||.|| || |..||| ||||. |..||....| WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL P--------------------AVKNMLSQNSQFTEYPVSQLRKHFQE----------------------------------KTSEMGLSLLQGLLTYDPK | ..| ...| .| ..| ... | . .. .. ||...|.|||. PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD QRLSADAALKHGFF .|..|. ||.| .| KRITAEQALQHPYF |
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Kinase | Pitslre.AA | CDK10 | 558-851 | 50 | 5.5e-124 | 418.21 | In-house | 1-285 (285) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-285/285 Sequence Identity: 50% (148 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSF | |||. |||||.||||.| |..||||||. .|.|||.| || .|||| |.. .|.||| ..|.||| .| ||.||.| | || ||.. | | | FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNM---PQPF FPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAEFLQM .|||.. |.||.. ||||...||||| ||||.. || .|| |||||| || |.| | .|||||||||||| . | ||.| |||| .| | TETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVH LPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALKHGFF ||.|| ||| .. | . ||||.|.||||...||.| || . | |.. |. |. |. ||. |. |.||.| |. .|. .| KPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMV-----QNFTLKKQPYNNLKHKFH-WLSQSGRRLLNFLFMYNPKKRATAEECLESSYF |
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Kinase | Pitslre.AA | CDK5 | 558-851 | 43 | 1.6e-119 | 379.43 | In-house | 1-287 (287) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-287/287 Sequence Identity: 43% (128 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSF .. ...| |||||.||.|..| | ||||||| ... | || | | .||| | .|.||| .. . |. .| .. ||| |. .. YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEK--KLTLVFEFCDQDLKKYMDSCNG---EM FPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAEFL-Q . .| . |||. .| |.. .|||||| ||| . .|.|| .|||||| .| |.. |.. |||||||.| |. | .|||.||.||.|||||| DMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA MLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQ-LRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALKHGFF ||||| .. |.| |||| .|||.| ||. |.|| | |. ||. | . .. .. .| |. |||..| ..|.||.||.|||.| .| GRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNH---QQYPMYPAHQSWQQIVPK-LDEKGMDLLQKMLQCNPNQRISAKAALHHPYF |
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Kinase | Pitslre.AA | CDK7 | 558-851 | 38 | 1.9e-119 | 319.86 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-288/288 Sequence Identity: 38% (115 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLK----MEKEKEGFPITSLREINTLLKGQHPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNR .. . | ||....||.| |. |..||| |. | . | | | .||| | ||.|.. . | . | |.|. . || . | YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFM--HKSNIQLVFDFMDWDLE---VVIKDK KQSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAE . . | ..| . ..|. . ..| ||||||||| |||.. |.||..|||||| |||| . ||. ||| |||||||| | | .|.||||||||| SIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAE FLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPV---SQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALKHGF . | .|| |.|| | |||. ||||.|. ||. .... .|...| ||. | . . | |..|..| .| .|... .||. . LMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDY-------IKFKDFPGYSRTPLRHIFTAASDDL-LDLMCGMWTMNPCKRWTCTQCLKMPY F | F |
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Kinase | Pitslre.AA | CRK7 | 558-851 | 35 | 1.2e-99 | 337.31 | In-house | 1-343 (343) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-343/343 Sequence Identity: 35% (124 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKE---KEGFPITSLREINTLLKGQHPNIVTVREIVVG------SNMDK--IFIVMDYVEHDLKSL .. .. | ||||| || ||.|.|.|.||||...|. | |||||||. ||| | .|.|||. .|||. .. .| .. | .|. ||| | YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL METMKNRK--QSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPI--KKYTSLVVTLWYRAPELLLCSPVY---- .| | . | ....||. ||| .. .|.. .||||.| ||.|. .|..| |||||| | | ..|| |.|||||.||||| | LES----KEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQH ----------------------------------STPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQF . ||.||.|||..| . |.|.|. |.. | |.| |.|| || ..|| |.. . |. ILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWW-NTMKPKRQY TEYPVSQLRKHFQE-----KTSEMGLSLLQGLLTYDPKQRLSADAALKHGFF . . ||. | . .. | || ..|..||| | .| .| |..| N----RRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF |
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Kinase | Pitslre.AA | S_TKc | 558-851 | 26 | 1e-93 | 318.54 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-231/231 Sequence Identity: 26% (82 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNIVTVREIVVGSNMDKIFIVMDYVEH---DLKSLMETMKNRK .. |. | .|..|.||....|.|..|||.|..| .. .|||. | | .|||||. .. . |....||.|... ||..... .. .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG --QSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYST-PIDVWSVGCIF . | . .......|...|....|...|.||||| .|.||.. .|..||||||.. |....|.||.|||.| |.. ..|.||.|||. LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL AEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALK---- .|.| |.|| .....|| .| |. ........|..||..|..| ||. YEMLCGYPPFP------QMQMMFKKIG------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD ---HGFF | .| IKCHPWF |
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Kinase | Pitslre.AA | Pkinase | 558-851 | 29 | 1.3e-87 | 302.13 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-293/293 Sequence Identity: 29% (92 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLR--EINTLLKGQHPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETM----K .... .| .|..|.||....| |..|||.|..| ..||.....| .| || ... .|||||. .... |.| .||.|.|..|. .|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLY-VMDLFDYIST NRKQSF--FPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGIL----KVGDFGLAREY-GSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDV |. .| . |.|. |.||.....|...|.||||| .|.|....| . |..|||||. . . .|....|.||.|||... .. |....|. WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM WSVGCIFAEFLQMLPLFPGK----SEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRL ||.|||..|.| |.|||. . .|.. .|.. .|.|.. || . . . . . . . .. | ..|| ..... ..|..|||.|. WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H--------F-HWTF-HNWSEECKDFIKWCLCKDPKKRP SADAALKHGFF .|. .|.| .| TAEQILQHPWF |
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Kinase | Pitslre.AA | CDK4 | 558-851 | 39 | 8.5e-84 | 284.7 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-290/290 Sequence Identity: 39% (119 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKE--GFPITSLREINTLLK----GQHPNIVTVREIVVGSNMDK----IFIVMDYVEHDLKSLM .||.. | || || |||| | | .||||. . . | | |. .||| .... ||||| .. . | | .|. .. ||. .. YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREI-SVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYL ETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSV . | . | .| .. ||||.| || . | ||||| |.|.. | .| ||||||.|.. . |..|||||||||| || |. | ||.| ||| D--KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQM-ALTPVVVTLWYRAPEVLLQSY-YNTPVDMWSV GCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALK |||||| |||.|.|| | | .||. |.| |. || || . | . .. | | .. |. ||| |.|... |.|| ..|. GCIFAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLPW--------DHFPQRHPRPF-KDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQ HGFF |..| HPYF |
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Kinase | Pitslre.AA | PFTAIRE | 558-851 | 38 | 7.9e-78 | 264.87 | In-house | 1-287 (287) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-287/287 Sequence Identity: 38% (114 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKG-QHPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQS .. |.. ||.| ||... . .. .|||| ....| || | | || |||. .| |||. |. .| ||. ||. |. . YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQE-EGTPFTAIREA-SLLKNLKHANIVCLHDIIHTKET--LTFVFEYVHTDLCQYMDKHPG---G FFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAEFLQ | |. |||| . | .|||||| |||.||.| || |||||| | . | . ||||||| | || | ||| .|.| ||||| | .. MHPNNVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMW MLPLFPGK-SEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFT--EYPVSQLRKHFQEKT-SEMGLSLLQGLLTYDPKQRLSADAALKHGFF |.||| | |..||| ||||.| ||| ..|| | .|. | .|.. . . .|....| . |..|.||..|..| .| GQPAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPH-----WFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF |
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Kinase | Pitslre.AA | TyrKc | 558-851 | 19 | 1e-12 | -17.1 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 558-851 Range on HMM: 1-280/280 Sequence Identity: 19% (65 aa) FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKG--QHPNIVTVREIVVGS-----NMDKIFIVMDYVEH-DLKSLMET . . . || .|.||... | . || | || .. .| | .||.. . | .||||| ... . . ..||| |..| |||. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDF----MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK MKNRKQSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSP-----IKKYTS------LV--VTLWYRAPELLLCSP ... . . . | . ..||.. . |||| . | |...... |..||||.|. .. |.| . . . ||| . HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG VYSTPIDVWSVGCI------FAEFLQ--M----LPLFPGKSEIDELNRIFKELG----TPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQEKT ...| |||| | . . | .. . ... .| . | . . KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------------------FVCCP SEMGLSLLQGLLTYDPKQRLSADAALKHGFF .|| . . .||..| . . | .| DEMYQ-IMKQCWHEDPEDRPTFSEI--HECF |
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Kinase | Pitslre.AA | Pkinase_Tyr | 566-708 | 30 | 2.2e-11 | 39.21 | Pfam | 9-159 (270) | Show / Hide |
Range on Protein: 566-708 Range on HMM: 9-159/270 Sequence Identity: 30% (48 aa) EGTYGVVYRAKDK----RTNEIVALKRL---KMEKE--KEGFPITSLREINTLLKG-QHPNIVTVREIVV--GS-NMDKIFIVMDYVEH-DLKSLMETMK || .|.||... | |. || | | |... .| | .||.... . .||||| ... | | .|.||| |..| ||.. . . EGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF----MREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYLRKHR NRKQSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAR . ||.. . . . .| .. ..|... . |||| . | |...... |..|||||| EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR |