Gene Par-1 (Fruit Fly)

Par-1

Species: Fruit Fly
Alias: C-TAK1-like, CG11960, CG8201, DPAR-1, l(2)k06323, Par-1, SFO033, PAR-1
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 56D8--11,

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
Par-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
Par-1.AA Protein Various 938 None Fasta, JSON

Protein domain

Protein domains of Par-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Par-1.AA MARK 253-504 57 3.4e-181 596.79 In-house 1-262 (262) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-262/262
Sequence Identity: 57% (151 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLDHPNIVKLFQVIE--TEKT-LYLIMEYASGGEVFDYLVLH--GR
||..||||.|..|||||| |..||..|||||..|..||.  ......||..|||.||||||.|||.|||  ||.. .|||||||||||..||.. |  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

MKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSEL--NIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLV
..|.|||. ||||||||.|||.|.|.|||.|.||.|.|..   ||||.|||||....||.||.||||.|||.|||.|..|.||||.||.|||||.||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

SGSLPFDGST--LRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM
.|..||||.|  . ||....|||||.||...|..|.||....|..|| .|...| || ..||
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase Par-1.AA CAMKL 253-504 49 8.9e-171 549.36 In-house 1-297 (297) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-297/297
Sequence Identity: 49% (148 aa)

YKLIKTIGKGNFAKVKLAKH-LPTGKEVAIKIID--KTQLNPGSLQK-----------LFREVRIMKMLD---HPNIVKLFQVIETEKT------LYLIM
|...||.|||.|.|||||.| . ||..|||||||  |....| ....           ..||..|||||.   ||||.||..||||...      .||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYASGGE--VFDYLVLH----GRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSEL--NIKIADFGFSNEFTP-----GSKLDTFCGSPPYA
||.||||   |||.| |    |||.|.|||  ||||||||.|||...|.|||.|.||.|||.    ||||.||||||...|     | ||.||||||||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFQG--KKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLR---------ELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM
|||.|||  |.||||.||.||.|||||..| | ||||. |.          ....... ....|....| ||..|.|| |. || ||.... || ..||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase Par-1.AA QIK 253-504 58 1.8e-164 552.72 In-house 1-272 (272) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-272/272
Sequence Identity: 58% (159 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGR------
| . .|||||||| ||||.|  | ..||||||||.||.   |||..||| |||||.||.|.||.||.||.. .|...||.|.|| ||||. |||      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------MKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVD
              |.|.||| .| ||.|||.|||.. |.||||||||.|||...||||||||||| |..|  | |.||||||||||.|.||.||||.||
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

VWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM
.||.||.|| ||.|.|||||.|| .||.||| ||.||||.||.||| | |. ||..|..| . . |.  .||
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase Par-1.AA CAMK 258-504 31 1.4e-143 465.93 In-house 1-425 (425) Show / Hide 
Range on Protein: 258-504
Range on HMM: 1-425/425
Sequence Identity: 31% (134 aa)

TIGKGNFAKVKLAKHLPTG------------KEVAIKIIDKTQLN--------------------------PGSLQKLFREVRIMKM-------LDHPNI
|.|.|.|.||||..|  |.            ..||||||||..|                           | ......||..|||.       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLFQVIE------------TEKT--------LYLIM---EYASGG----EVFDYLVLH---------------GRMKEKEARVKFRQIVSAVQYCHQKR
.||..|.|            | ..        .|..|   ||.|||    ..|||.| |               ||..|.|||  ||||.|||.|||.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKAENLLLDSE-----------------LNIKIADFGFSNEFTP------------------------GSKLDTFCGSPPYAA-PELFQG-----
|.||||| ||.|||.                   ||||.||||.|.|.|                        | |. ||||.|.|.| ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KKYDGPEVDVWSLGVILYTLVSGSLPFDGS-------------TLRELRERVLRGKYR-IPFYMST-----------------------DCE
        |.|.||..|.||.|||||....| .||.|.             ...|| |....|||. .|.|.|.                       .| 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLLRKFLVLNPAKRASLETIMGDKWM
.|.|| |. .| ||...| .. ..||
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Par-1.AA AMPK 253-504 48 6.7e-141 421.0 In-house 1-254 (254) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-254/254
Sequence Identity: 48% (122 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLDHPNIVKLFQVI-ETEKTLYLIMEYASGGEVFDYLVLHGRMKEK
| . ||||.| | |||...|  ||..|||||..|. .   . . .. ||..|.|.. ||.|..|..|| ||.. ....|||.|||| ||| | |||..|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF
||.  | ||.|.| |||.  | ||||| |||||| . ||||.||| ||  . | .| | |||| |||||. .||.| |||||.|| ||||| .. | |||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM
| .  ..|  ... |.| || ..|.....|... |  .| ||.. . |. ..| 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase Par-1.AA NuaK 253-504 48 2.3e-136 361.22 In-house 1-252 (252) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-252/252
Sequence Identity: 48% (123 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKE
|...|| ||| . |||||    ||.||||| | |     .  . .  ||..||  |.||.|.. . | |    . ..|||||||| .||.   ... |.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD
||  |||||||| |||. ||.||||| || ||| . |.|||||| || .  .  | |||||| || ||   |. | ||||| |||||.|||.| |..|||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM
|.  ..|   . .|.|. |   |. |. | |. |  || .||... |    |.
GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV
Kinase Par-1.AA NIM1 253-504 43 1.1e-117 347.22 In-house 1-258 (258) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-258/258
Sequence Identity: 43% (112 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIID--KTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEK
| . . || ||| ||||. |  | . |||||.|  || .    .  | ||.  |  . |||||.|. |.||   ..|.||||.||| . .    | . | 
YRFCGEIGRGNFSKVKLGVHQLTKEKVAIKIMDLDKTKMDQKTQRMLSREIQCMECMHHPNIVRLYEVVETLTRVHLVMEYARGGELYTHIHQEGKLREI

EARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTP----GSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSG
..   | ||||||.  | . |.|||.|||| .. |.  .|..|||||         . .|.|||||||||||||||   | |. |||| ||..||  . |
HCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEYVDVWALGILLYFMMTG

SLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM
  ||   |  ..   .| |.| || | |  |  | |  |   |. |.  . .| . ||
VMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase Par-1.AA BRSK 253-504 52 3e-111 375.9 In-house 1-254 (254) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-254/254
Sequence Identity: 52% (134 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLN--PGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEK
|.| || |||   .|||  |  ||| |||||| |  |   .  |.|  ||. |||. |||.. |.. | |. | ||||.|. |||| |||||  ||.. |
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF
|||  ||||.||. .|| . | ||||| |||||| . ||||||||       .. |.| |||| || ||  .| ||||   |||| ||||| |  | |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM
|   ||.| |.| || . .| .   || .|||. .  .|.|| ||. |    | 
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase Par-1.AA S_TKc 253-504 35 1.2e-109 371.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-231/231
Sequence Identity: 35% (96 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASG--GEVFDYLVLHGR----
|.....|||| |.||....|  ||..||||||.         ... ||..|.|. .|||||||. |... . ||..|||..|  |..|||.. .||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--MKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLV
  . | .||  ..||..|..|||...||||||| ||.|||.  .|||.|||.. ..      .||||.| | |||..   .|.....|.||.|.||| ..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMG-------DKWM
.|  ||.  .. .. ....          | .. ...|| |. .|.|| .   ..        . |.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Par-1.AA SNRK 253-504 48 3.8e-105 345.31 In-house 1-254 (254) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-254/254
Sequence Identity: 48% (123 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGR-MKEKE
| | ||.|.| || ||||.|. ||. ||.|.||||..   |  .||.||| ||.  |||||.|. ||.|   ||||.|   |....||.. | . ..|. 
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL

ARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELN-IKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF
||  |.||. |..||||....||||| || .    .  .|. ||||||.| || ||.|.|||  |.|||.  | .|| | ||.|||||||| || | .||
ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF

DGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM
.     |   ...  || .|  .|..| .|. . || .| |||||| |    |.
QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase Par-1.AA Pkinase 253-504 34 2.7e-102 350.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-293/293
Sequence Identity: 34% (101 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFR--EVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGG----EVFDYLV--LH
|.....||.|.|..|....|  |||.||.|||.|   ... .| ..|  |..|||.|.|||||.|. . |... .|..|||. ||    . |||.    |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRM--KEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNI----KIADFGFSNE--FTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL
|..   |.|..  ..||.....|||...||||||| ||.|.|.. .|    ||.|||..      ..| ..||||.|.|.|||. .| .|.||.||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYTLVSGSLPFDGS------TLRELRERVLRGKYRIPFY---------------------MSTDCENLLRKFLVLNPAKRASLETIMGDKWM
|.||| ...| .||.|.      . ... .|....... ...                     .| .|  .... | ..|.|| . | |. ..|.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Par-1.AA TSSK 253-504 36 1.9e-101 333.73 In-house 1-289 (289) Show / Hide 
Range on Protein: 253-504
Range on HMM: 1-289/289
Sequence Identity: 36% (106 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKE----------------VAIKIIDKTQLNPGSLQK-LFREVRIMKM-LDHPNIVKLFQVIETEK-TLYLIMEYAS
|.. |.||.|..|||..| .  . ..                |||||||..   .  |.| | ||  ||.. |.||||..... .||.    |..||||.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

GGEVFDYLVLH------GRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGS------KLDTFCGSPPYAAPELF
.| ...|   .      |...|..||  |||.||||.||| . . ||||| ||.|||   |||..||||........      .. |||||  ||||| .
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

QGKKYDGPEVDVWSLGVILYTLVSGSLPFDG--STLRELRERVL-RG-KYRI--PFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM
.|..||.  .||||.|||||..| |..|||   | .. . ...  .. ....      |..| .|.|. | ..| .|.... |. . ||
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase Par-1.AA TyrKc 253-503 25 2e-29 105.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 253-503
Range on HMM: 1-280/280
Sequence Identity: 25% (74 aa)

YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML--DHPNIVKLFQVIETE-------KTLYLIMEYASGGEVFDYLVL
 .|.|..| |.| .| ...      .||.| . .       .. . || |||..|  .|||||.|. |. ..       . |...|||...|   |||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HGR-MKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPG------SKLDTF----CGS--PPYA--APELFQGKKYDG
|..  . |.      || .  .| |.|..||||| | | |..... .||.||| | . . .      ..  .     .|    |.   ||| .. .|.  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-

PEVDVWSLGVILYTLVS-GSLPFDG-----STLRELRERVLRG-KYRIPFY--------MSTDCENLLRKFLVLNPAKRASLETIMGDKW
.. |||| || .. . . |  |  |      . .|..|.| .|   ..| .        ....  .. ..    .|..| . ..|  ...
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase Par-1.AA Pkinase_Tyr 253-395 31 2.8e-29 99.81 Pfam 1-156 (270) Show / Hide 
Range on Protein: 253-395
Range on HMM: 1-156/270
Sequence Identity: 31% (50 aa)

YKLIKTIGKGNFAKVKLAKHL----PTGKEVAIKIIDKTQLNPGS--LQKLFREVRIMKML-DHPNIVKLFQVIE-TEKT--LYLIMEYASGGEVFDYLV
 ...|..|.|.| .|....       |. .||.|.. | .  .    .....||..||| | .|||||.|  |.   ..   .|..|||. .|   ||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

LH----GRMKEKEARVKF-RQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFG
 |    .. . |.  ... .|| .. .| ..|..||||| | | |..... .||.|||
KHREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase Par-1.AA Pkinase_Tyr 432-470 34 0.204269 5.42 Pfam 196-236 (270) Show / Hide 
Range on Protein: 432-470
Range on HMM: 196-236/270
Sequence Identity: 34% (14 aa)

DVWSLGVILYTLVS-GSLP-FDGSTLRELRERVLRGKYRIP
|||| || .. ... |  | . | .  |. |.. .  || |
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMP
UBA_CAMKL Par-1.AA UBA_CAMKL 525-562 36 2.2e-14 49.7 In-house 1-41 (41) Show / Hide 
Range on Protein: 525-562
Range on HMM: 1-41/41
Sequence Identity: 36% (15 aa)

DPKRIEALVAM--GYNRSEIEASLSQVRY-DDVFATYLLLG
|...|. ...|  |..| ||. ||.. .| ... |||.||.
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL
UBA Par-1.AA UBA 525-562 23 5.8e-09 37.02 SMART 1-38 (38) Show / Hide 
Range on Protein: 525-562
Range on HMM: 1-38/38
Sequence Identity: 23% (9 aa)

DPKRIEALVAMGYNRSEIEASLSQVRYDDVFATYLLLG
. ..|. |. ||..| |....|..  ...  |...|. 
YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS
KA1 Par-1.AA KA1 892-938 41 5e-21 73.72 Pfam 1-48 (48) Show / Hide 
Range on Protein: 892-938
Range on HMM: 1-48/48
Sequence Identity: 41% (20 aa)

TDSLVQWEIEVCKLP-RLSLNGVRFKRISGTSIGFKNIASRIAFDLKL
... |..||.|||.| ||.|.||.|||.|| .  .|.....|  ...|
EPEVVKFEIQVCKVPGRLGLYGVDFKRVSGNQWQYKDLCTKILKEMRL