Gene CG11870 (Fruit Fly)

CG11870

Species: Fruit Fly
Alias: EMK/KIAA0537, CG11870, SFO039
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 86A5--6,

Classification

Group: CAMK
Family: CAMKL
Subfamily: NuaK

Sequence

Name Sequence Type Origin Length Description Download
CG11870.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
CG11870.AA Protein Various 434 None Fasta, JSON

Protein domain

Protein domains of CG11870.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG11870.AA NuaK 82-333 71 1.1e-265 708.5 In-house 1-252 (252) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-252/252
Sequence Identity: 71% (181 aa)

FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLTEEE
....|.||.||||||.|.....||.|||||.|||||||.|.|.|.||||..||||..||.||||||||||..|.|.|||.|.|||||||.||.|.|.|.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYGSMPFD
||..|||...||.|||||.||||||||||||||...|||||||||||...||..|.||||||||||||||.|.||.|||||||||||||||.|||.||||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GSNFKRLVKQISQGDYYEPRKPSRASTLIRDMLTVCPRKRASIEQICSHWWV
|..||.||||||||.||||.|||.|..|||.||.|.||.||.|..||.||||
GHDFKHLVKQISQGAYYEPCKPSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase CG11870.AA CAMKL 82-333 44 1.1e-151 487.4 In-house 1-297 (297) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-297/297
Sequence Identity: 44% (134 aa)

FDIIKKLGQGTYGKVQLGIN-KETGQEVAIKTIKKCKIEA-------------EADLVRIRREVQIMSSVH---HPNIIHIYEVFENREK------MVLV
..|.| ||.|..|||.|... . ||..|||| |.| ||               |.|. |||||.|||....   |||||..|||.|..|.      ..||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEFAAGGE--LYDYLSER----KVLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKG--NAKIADFGLSNVFDD-----QRLLGTFCGSPLY
|| . |||  |.||. ..    . ..|.||||.|||.  ||.|||.|.|.|||.|.|||||||.|  |.||.|||.|| ...      ..| |||||| |
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ASPEIVEG--TPYQGPEVDCWSLGVLLYTLVYGSMPFDGS--------NFKRLVKQISQGDYYEP---RKPSRASTLIRDMLTVCPRKRASIEQICSHWW
..|||..|  .|| ||.||.||.||.||..|.| .|||.         |. .| ..| .| ||.|   . . ..  ||| ||.|.| ||..|.|| .|.|
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

V
.
M
Kinase CG11870.AA CAMK 87-333 29 3e-132 428.74 In-house 1-425 (425) Show / Hide 
Range on Protein: 87-333
Range on HMM: 1-425/425
Sequence Identity: 29% (126 aa)

KLGQGTYGKVQLGINKETG------------QEVAIKTIKKCKIE-------------------------AEADLVRIRREVQIMSS-------VHHPNI
.||.|..||| |.|.|.|.            |.|||| |.| |.                           . |. ..|||..||..       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IHIYEVFE------------NREK--------MVLVM---EFAAGGEL----YDYLSER---------------KVLTEEEARRIFRQVATAVYYCHKHK
|..|||.|            . .|        |..||   |.. ||||    .||. |.               . .||.||||.|||.. || |||.|.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ICHRDLKLENILLDEK-----------------GNAKIADFGLSNVFDD------------------------QRLLGTFCGSPLYAS-PEIVEG-----
|.|||||.||||||..                 .| ||.|||..|.||.                          .. ||||.| |.. ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------TPYQGPEVDCWSLGVLLYTLVYGSMPFDGS-------------NFKRLVKQISQGDYY-EPRKPSR------------------------AS
         || ||..|.||.||.||... | .||.|.             | ..| ..| .|.|. .| . |                         . 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

TLIRDMLTVCPRKRASIEQICSHWWV
 ||| ||.| | ||..|||. .| |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CG11870.AA AMPK 82-333 48 7.79999999999e-125 372.51 In-house 1-254 (254) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-254/254
Sequence Identity: 48% (122 aa)

FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIYEVF-ENREKMVLVMEFAAGGELYDYLSERKVLTEE
. | |..| ||.||| .|. . ||..|||| . | ||  ...  ||.||..|. .. ||.||  |||  |  . . .|||...||||.||   .. |.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYGSMPF
||.| | |.  .| |||.|.| |||||.||.|||.. | ||.||||||.  |  .| | |||| ||.||...| .| ||||| || || || .. |  ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DGSNFKRLVKQISQGDYYEPRKPSR-ASTLIRDMLTVCPRKRASIEQICSHWWV
| .|   | | | .|.|| |.  |. |. ||. ||.| | ||..|..|  | | 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase CG11870.AA MARK 82-333 45 6.4e-121 396.91 In-house 1-262 (262) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-262/262
Sequence Identity: 45% (120 aa)

FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIYEVFE--NREK-MVLVMEFAAGGELYDYLSER--KV
. ..| .|.|.|.|| |...| ||..||||...| |.     .  ..||..||....|||||  ..|.|  ....  .|.|| | |||||||. ..    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKG--NAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLV
|.||||||||||.  ||.|||.. |.|||.|.||||.||.|  |.||.|||.|. .   ..| ||||.| |..|||... || ||.|| |||||.||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

YGSMPFDGSN--FKRLVKQISQGDYY-EPRKPSRASTLIRDMLTVCPRKRASIEQICSHWWV
 |. ||||..  .| | |.|  |.|   .. .  .  ||. .||| | .|..||.| .| |.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase CG11870.AA S_TKc 82-333 35 2.7e-104 353.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-231/231
Sequence Identity: 35% (96 aa)

FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIYEVFENREKMVLVMEFAAG--GELYDYLSERKV---
..|..|.|.|..||| ....|.||..|||| ||           .||||.||... |||||...|.||.. ... .|||.. |  |.|.||. .|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTL
   ..| .||....|.. |. |||.|.|.||||| |||||||  . ||.||||. ..       ||||.| | .||..   .| ....| ||.|..|| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VYGSMPFDGSNFKRLVKQISQGDYYEPRKPSRASTLIRDMLTVCPRKRASIEQICS-------HWWV
..|  ||.  . ... |.|          .. |  .|| .|.. |.|| .. ..         | |.
LCGYPPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG11870.AA QIK 82-333 43 2e-102 346.58 In-house 1-272 (272) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-272/272
Sequence Identity: 43% (119 aa)

FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKV-----
.|| . .| | .. | |. .. | ..|||| | | ....| .| .. |||||| .  ||.||  |.| |  . | .|.|.. .||..||| .        
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEE-NLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEV
               ..|.||||.| |...||.||||..| ||||| ||||||.  | ||||||.|| |    || |.|||| || ||. ||  | ||.|
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DCWSLGVLLYTLVYGSMPFDGSNFKRLVKQISQGDYYEPRK-PSRASTLIRDMLTVCPRKRASIEQICSHWWV
| ||.||.|| || |..||||.. . | . .  | .  |   ..   .||| ||.| | .| .|.||| | | 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase CG11870.AA Pkinase 82-333 32 9.5e-100 342.49 Pfam 1-293 (293) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-293/293
Sequence Identity: 32% (95 aa)

FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIR-REVQIMSSVHHPNIIHIYEVFENREKMVLVMEFAAGG----ELYDYLS--ER
. |..|.|.|..|.| ....| ||..||.|.|||.... . |  ..| .|.||| ...||||. .|..||.. .. .|||.. ||    .|.||.|  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KVL--TEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNA----KIADFGLSNV--FDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSL
...  .|.|......|.. ...|||...|.|||||.||||.|..|.     ||.||||. .     .. . ||||.| |..||.. | .| ||.|| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLYTLVYGSMPFDGS------NFKRLVKQISQGDYYEPRK----------------------PSRASTLIRDMLTVCPRKRASIEQICSHWWV
|..|| .. |  ||.|.      . . ....| .... ...                       .. .  .|...|...| || ..|||. | |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CG11870.AA CAMK1 82-333 37 1.9e-94 274.94 In-house 1-276 (276) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-276/276
Sequence Identity: 37% (104 aa)

FDIIKKLGQGTYGKVQLGINKET---GQEVAIKTIK-KCKIEAEAD--LVRIRREVQIMSSV---HHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLS
. ..|..| |. ..| |...|||   |...||| |. |  .. . .  . ....|..|| .|   .||||| .||..|  ..  ||||   |||| |   
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

ERKVLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNA---K--IADFGLSNVFDDQR-LLGTFCGSPLYASPEIVEG---TPYQGPEVDC
|... ||..||.| .|.. ||.|.|.. |.||||| ||.|.  | .    |  |||||||  ||..  |. | ||.| |  ||..|.   .|| . ..|.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY-DKACDM

WSLGVLLYTLVYGSMPFDGSN-FKRLVKQISQGDYYEPRK-----PSR-ASTLIRDMLTVCPRKRASIEQICSHWWV
|| || .|.|  |  || ..|  . | ..|. ..|  | .      .  |  .|. ||.| | || ..||.  | |.
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CG11870.AA BRSK 82-333 43 5.4e-91 308.62 In-house 1-254 (254) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-254/254
Sequence Identity: 43% (111 aa)

FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIE-AEADLVRIRREVQIMSSVHHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLTEE
. . | ||.|. |.| ||. . ||. |||| | | |    |  | .. ||. ||  . ||.....|.|.||.  . |..|. .||||.||| ..  ||  
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYGSMPF
|||. |||.  |. .|| | ||||||| || ||||| | ||||||.  .  .  .| | |||| ||.||.. |  | |   | || || || |  | .||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DGSNFKRLVKQISQGDYYEPR-KPSRASTLIRDMLTVCPRKRASIEQICSHWWV
|  |  .|   . .| .  |   .  .  | | |..| | || |...|  | |.
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase CG11870.AA TSSK 82-333 37 9.4e-86 281.42 In-house 1-289 (289) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-289/289
Sequence Identity: 37% (110 aa)

FDIIKKLGQGTYGKVQLGINKETGQE----------------VAIKTIKKCKIEAEADLVR--IRREVQIMSS-VHHPNIIHIYEVFENRE-KMVLVMEF
..  ||.| |.|.|| ..  |..  .                |||| | .   .| .| ..  . || |||   ..|||||..|| ||.   |  .|||.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRK--KAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEY

AAGGELYDYLSER------KVLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDDQR------LLGTFCGSPLYASPE
|..| | .|  .|      . |.||.||. ||| . || ||| | . |||||.||||||. .| |..||| .....  .      |..|||||  ||.||
AEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPE

IVEGTPYQGPEVDCWSLGVLLYTLVYGSMPFDG--SNFKRLVKQIS-QGDYYE----PRKPSRASTLIRDMLTVCPRKRASIEQICSHWWV
|. | ||..  .| ||.|| ||..|.|.||||   || ... .|.. ..  .     .   ...  ||| ||.  |..|..|..||.| |.
ILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase CG11870.AA Ciliate-E2 82-333 26 1.4e-79 270.67 In-house 1-365 (365) Show / Hide 
Range on Protein: 82-333
Range on HMM: 1-365/365
Sequence Identity: 26% (99 aa)

FDIIKKLGQGTYGKVQLGINKETG-----------------------QEVAIKTIKKCKIEAEADLVRIRREVQ----------IMSSVHHPNIIHIYEV
...|||.|||..|.| .. .....                       ...|.|..|| .||.     .| ||..          |.... ||||| .||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--NREKMVLVMEFAAGGELYDYLSER-----------KVLTEEEARRIFRQVAT---------------AVYYCHKHK-ICHRDLKLENILLDEKGNA
|.  ..... ||||.. ||.|.||. ..           | .||.|...|..|..                |. |.|. . |.|||.|.||||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGLSNVFDDQ--------------------------------RLLGTFCGSPLYASPEIVEGTPYQG--------PEVDCWSLGVLLYTLVYGSMP
||.|||||  .||.                                 .  |.||.| | .|||..| .|..         ..| |||||.|| ...|  |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FDGSNFKRLVKQISQGDYYEPRK-------------------PSRASTLIRD----MLTVCPRKRAS-IEQICSHWWV
|         .|| |...  | .                   .  .  ||.     || . | || . .|||  | | 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CG11870.AA Pkinase_Tyr 82-227 32 1.4e-30 104.2 Pfam 1-158 (270) Show / Hide 
Range on Protein: 82-227
Range on HMM: 1-158/270
Sequence Identity: 32% (53 aa)

FDIIKKLGQGTYGKVQLGINK----ETGQEVAIKTIKKCKIEAEAD---LVRIRREVQIMSSV-HHPNIIHIYEVFE-NREK--MVLVMEFAAGGELYDY
  ..||||.| .|.| .|. |    .|...||.|..|     |  .   .    ||..||..  |||||.  | |    .|   . .|||....| |.||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LSE----RKVLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLS
| .    .. || ..   . .|.| .  | . ... ||||   |.|..|.. .||.||||.
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase CG11870.AA TyrKc 82-331 25 2e-23 85.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 82-331
Range on HMM: 1-280/280
Sequence Identity: 25% (74 aa)

FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSV--HHPNIIHIYEVFENR-------EKMVLVMEFAAGGELYDYLS
   .|||| | .|.| .|. |   ..||.|..|...      .  ..|| .||...  |||||. .| |           | . .|||....| | ||| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ERKV-LTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLS-NVFDD-------QRLLGTF--CG---SPL-YASPEIVEGTPYQ
...  |. ..   .  |.|    | |.... ||||   |.|..|.. .||.||||| .. ||       .    .   .|    |.   .||      . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-

GPEVDCWSLGVLLY-TLVYGSMPFDG-----SNFKRLVKQISQGDYYEPRKPSR--------ASTLIRDMLTVC----PRKRASIEQICSHW
 .. | || ||...  . || .|  |      . ....... ||..  ...|          ... . .. . |    | .| . ..|.. .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYR--MPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF