Gene CG3608 (Fruit Fly)

CG3608

Species: Fruit Fly
Alias: SFO227x, CG3608
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 60D15--16,

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-B

Sequence

Name Sequence Type Origin Length Description Download
CG3608.AA Protein Various 518 None Fasta, JSON
CG3608.kin_dom Protein Kinase Domain None 8 None Fasta, JSON

Protein domain

Protein domains of CG3608.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ABC1 CG3608.AA ABC1 137-253 44 2.7e-64 218.44 Pfam 1-126 (126) Show / Hide 
Range on Protein: 137-253
Range on HMM: 1-126/126
Sequence Identity: 44% (56 aa)

QDLHCNPEEIFDSFEREPLGTASLAQVHKARLKT-GELVAVKVQHPYVKGNSRVDMKTMELAVNVLARIFPD-----FKIHWLVEESKKNLPIELDFLNE
..|.|..||||..|..||...||.||||.||||. || |||||||| || ....|...|.. .....|.||.     |...|.|.| .|||| |||...|
EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE

GRNAEKVAKQFKKY---SWLRVPKIY
..|.|.... |...   .|..|||.|
AKNMERFRENFRHWHRQPWVYVPKVY
Kinase CG3608.AA ABC1-B 137-253 46 4e-61 209.4 In-house 1-125 (125) Show / Hide 
Range on Protein: 137-253
Range on HMM: 1-125/125
Sequence Identity: 46% (59 aa)

QDLHCNPEEIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMELAVNVLARIFP------DFKIHWLVEESKKNLPIELDFLNE
.||  |.|..|  |. .|...|||||||.| |..|| |||||||| .. ... ||..||| | |.   ||      .|...|...| .|||| ||||.||
KDLG-NIEDVFSEFDQKPIAAASLAQVHRAKLHDGETVAVKVQHPWLRKQFHYDMMMMELFVKVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELDFYNE

GRNAEKVAKQFK---KYSWLRVPKIY
.|||||.. .||   ..  |.||.|.
ARNAEKCRQMFKKFKHFDFLYVPRIH
Kinase CG3608.AA ABC1 137-253 44 2.8e-55 189.96 In-house 1-123 (123) Show / Hide 
Range on Protein: 137-253
Range on HMM: 1-123/123
Sequence Identity: 44% (55 aa)

QDLHCNPEEIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMELAVNVLARIFP-----DFKIHWLVEESKKNLPIELDFLNEG
|||  |.|..| .|. .|...||.||||.|.||.|. |||||||| |. ... |...||. |...   ||     .|. .|.|.| .|.|| |.||.||.
QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKDGQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEA

RNAEKVAKQFK--KYSWLRVPKIY
|||||.. .||  ..  ..||.|.
RNAEKCRQLFKKFHWPFFYVPRIH
Kinase CG3608.AA ABC1-A 150-184 54 2.1e-10 32.42 In-house 1-35 (216) Show / Hide 
Range on Protein: 150-184
Range on HMM: 1-35/216
Sequence Identity: 54% (19 aa)

FEREPLGTASLAQVHKARLKTGELVAVKVQHPYVK
||  |   ||  |||.|.|| |  ||||.| | |.
FEEMPFACASIGQVHQAVLKDGREVAVKIQYPGVA
Kinase CG3608.AA S_TKc 149-463 14 7e-06 -90.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 149-463
Range on HMM: 1-231/231
Sequence Identity: 14% (51 aa)

SFEREPLGTASLAQVHKARLKT-GELVAVKVQHPYVKGNSRVDMKTMELAVNVLARIFPDFKIHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYSWL
    ...|  . ..|.|.| |  |..||.|. .                                      ...  |.. | .  . . . | .  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------------------------------EHIRREIQILKK--HHPNIVKLYDVFQD-

RVPKIYWKYSSSRVLVMEYLEG--GHVTDLDYIRRNKIDS--FAVANRIGQLYSEMIFRT-------GFVHSDPHPGNILVRRTPENSLEIVLLDHGLYA
          ..  .||||..|  | .  .|||....     |       . |   |..        |..| |  | |||. .      .| . | || .
----------DHLYMVMEYCDGDLGDL--FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLAR

NLTDKFRYDYSNLWLS--ILKVDRKAMRQHSEQLGI-KGDLYGL---FACMVTGRP-WETVMQGLTKVKYSKEEKNTLQNNTSLVLPHISDVLEQVDRQM
 |     .  .  ...  .|            . |  | | . .   .. |..|.| ..  || . |.                                
QL---TTFCGTPWYMAPEVL------------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG------------------------------

LLILKTNDLIRGIESTLR--TQNRMTAFWVMS-------KCCV
     . ...  |.  |.   ..|.||  ..           .
-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG3608.AA ABC1-C 299-317 73 1e-05 13.38 In-house 128-146 (307) Show / Hide 
Range on Protein: 299-317
Range on HMM: 128-146/307
Sequence Identity: 73% (14 aa)

MIFRTGFVHSDPHPGNILV
|||   ||| | |||||||
MIFVDNFVHADLHPGNILV
Kinase CG3608.AA IKK 150-182 32 0.00016 11.59 In-house 2-35 (297) Show / Hide 
Range on Protein: 150-182
Range on HMM: 2-35/297
Sequence Identity: 32% (11 aa)

FEREPLGTASLAQVHKARLK-TGELVAVKVQHPY
. ...||. . ..| ..|.| ||. ||||. ...
EMCDRLGQGAFGNVYHWRHKKTGRKVAVKHCNHM
Kinase CG3608.AA ABC1-C 174-201 39 0.078041 0.95 In-house 1-28 (307) Show / Hide 
Range on Protein: 174-201
Range on HMM: 1-28/307
Sequence Identity: 39% (11 aa)

VAVKVQHPYVKGNSRVDMKTMELAVNVL
||||| || .     .|.  | .   ||
VAVKVLHPGLLAQVHMDLLLMKIGSRVL
Kinase CG3608.AA ABC1-A 248-269 40 0.332724 0.26 In-house 99-120 (216) Show / Hide 
Range on Protein: 248-269
Range on HMM: 99-120/216
Sequence Identity: 40% (9 aa)

RVPKIYWKYSSSRVLVMEYLEG
.||..   |...||| ||  .|
YVPHVIDEYCTDRVLTMELMYG