Gene GL50803_95717 (G.lamblia)

GL50803_95717

Species: G.lamblia
Alias: GL50803_95717, GK230
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_95717.AA Protein None 1025 None Fasta, JSON
GL50803_95717.kin_dom Protein Kinase Domain None 273 None Fasta, JSON

Protein domain

Protein domains of GL50803_95717.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_95717.AA S_TKc 9-281 30 1.1e-67 232.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-281
Range on HMM: 1-231/231
Sequence Identity: 30% (87 aa)

YEYIGSIGQGAFGRVVKARNTDTTTEVACKIVSYEGVKDPESMFKESRILKHMHHPHIVQCYDVIDDKENCTLYVFMELCES---DLQRLIDDSKSKK--
|| .  ||.||||.| |.|...|  .||.||..       |.. .| .|||. |||.||..|||..|     ||..||.|.    || ..|.. ....  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

RMVPEAAIWGFLAQAIQALTYLHSPFNKKYQDEEGVTHNIGKVYHRDIKPANLLLDKEGNIKLADFNVSTAIKGDKLNSTKCGTPLYAPPEIHEGVREYH
.  ||  .. ...| ..|| |.||                 .. |||.||.|.|||.  .||..|| ... .      .| |||| | .||.       .
FPFPE-HARFYMYQICCALEYCHS---------------H-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-----GY

GG-AVDIWSLGCTIYHVCALRPPFVAVGMGPLIRMIRSGVYPEMPQFYSKELHEVIENMIRPKPACRISTADLLQ-------HNRI
|. ..|.||.||..|  .. .|||    |  ....|.           |.|. . |... .  |. |..  ..||       |  .
GKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase GL50803_95717.AA Pkinase 9-278 25 6e-59 206.94 Pfam 1-290 (293) Show / Hide 
Range on Protein: 9-278
Range on HMM: 1-290/293
Sequence Identity: 25% (80 aa)

YEYIGSIGQGAFGRVVKARNTDTTTEVACKIVSYEGVKD--PESMFK--ESRILKHMHHPHIVQCYDVIDDKENCTLYVFMELCESDLQRLIDDS----K
|. .. ||.|.||.| |... .|  .||.||..... |.  ... ..  | .|.|...||.||..||.  |  .  .|. ||.|| .|  ..| .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLY-VMDLFDYIST

SKKRMV--PEAAIWGFLAQAIQALTYLHSPFNKKYQDEEGVTHNIGKVYHRDIKPANLLLDKEGNI----KLADFNVSTA--IKGDKLNSTKCGTPLYAP
.... .  .|  .  .. | ...| |.||                 .. |||.||.|.|.|..|.|    |..|| ..    .  .  ..| |||| |..
WRHGCFYFSEWECKFYMYQILRGLEYCHSM----------------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMA

PEIHEGVREYHGGAVDIWSLGCTIYHVCALRPPFVAV------GMGPLIRMIRSGVYPEMPQFYS--------------------KELHEVIENMIRPKP
||..   ..|.| .||.||.||..| ..  ||||          .  .|..|... ...  .  .                    .|. ..|.......|
PEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP

ACRISTADLLQH
..|.. ...|||
KKRPTAEQILQH
Kinase GL50803_95717.AA NEK 9-195 31 3.9e-40 139.16 In-house 1-195 (286) Show / Hide 
Range on Protein: 9-195
Range on HMM: 1-195/286
Sequence Identity: 31% (66 aa)

YEYIGSIGQGAFGRVVKARNTDTTTE-----VACKIVSYEGV--KDPESMF-KESRILKHMHHPHIVQCYDVIDDKENCTLYVFMELCES--DLQRL---
||.|  ||||.||.| |.| . .  .     .. | .....   |. .    .| ||||...||.||  || . ...| .|.  || ||   ||...   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IDDSKSKKRMVPEAAIWGFLAQAIQALTYLHSP--FNKKYQDEEGVTHNIGKVYHRDIKPANLLLDKEGN----IKLADFNVSTAIKGD--KLNSTKCGT
|   | |. . .|  || ...| . || |.|.                  .|. ||||||.|. |.|..|    .|. ||..|   . .  ....|  ||
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGP-------------QRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGT

PLYAPPEI
| |. ||.
PYYMSPEV
Kinase GL50803_95717.AA CAMK 141-278 20 5.2e-34 106.45 In-house 196-422 (425) Show / Hide 
Range on Protein: 141-278
Range on HMM: 196-422/425
Sequence Identity: 20% (47 aa)

HNIGKVYHRDIKPANLLLDKE-----------------GNIKLADFNVSTAIKG------------------------DKLNSTKCGTPLYAP-PEIHEG
|. . . |||.|| |.|||.                  .|||..||  .. ...                        ... .| |||| |.. ||. .|
HSHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

V------------REYHGGAVDIWSLGCTIYHVCALRPPFVAV-------------GMGPLIRMIRSGVYPEMPQFYSK---------------------
             ..|.| ..|.||.|.  |     .||| .               .  | ..|..| |   | . |.                     
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

--ELHEVIENMIRPKPACRISTADLLQH
  |    | .| .. |  |.. .. |.|
SQECKDLIRKMLQVDPEKRMTIEQCLNH
Kinase GL50803_95717.AA CAMKL 141-278 31 2.8e-31 96.95 In-house 144-294 (297) Show / Hide 
Range on Protein: 141-278
Range on HMM: 144-294/297
Sequence Identity: 31% (49 aa)

HNIGKVYHRDIKPANLLLDKEG--NIKLADFNVSTAIK-G----DKLNSTKCGTPLYAPPEIHEG-VREYHGGAVDIWSLGCTIYHVCALRPPFVAV---
|. | . |||||| |.|||. |  |||..||  |. .. .    ... .| ||.| |..||| .|  ..|.| .|||||.| . |     . || .    
HSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN

-----GMGPLIRMIRSGVYPE-MPQFYSKELHEVIENMIRPKPACRISTADLLQH
         | ..|..| | .  . . | ...  |  |  ..|  |..  ....|
KQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH
Kinase GL50803_95717.AA MARK 141-281 35 9.4e-28 87.94 In-house 121-262 (262) Show / Hide 
Range on Protein: 141-281
Range on HMM: 121-262/262
Sequence Identity: 35% (51 aa)

HNIGKVYHRDIKPANLLLDKEG--NIKLADFNVSTAIKGDKLNSTKCGTPLYAPPEIHEGVREYHGGAVDIWSLGCTIYHVCALRPPFVAVG--MGPLIR
|... . |||||| |.|.|..|  |||..||  |. |. ... .| |||| |..||| .. ..| | .|||||||   |     . || . .  .  | .
HSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLK-KPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYK

MIRSGVYPEMPQFYSKELHEVIENMIRPKPACRISTADLLQHNRI
 |..|.|.  | . |||..  |  .. . |  |..  ....|  .
KILRGKYD-IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase GL50803_95717.AA CAMK 14-127 17 1.4e-27 85.4 In-house 1-197 (425) Show / Hide 
Range on Protein: 14-127
Range on HMM: 1-197/425
Sequence Identity: 17% (35 aa)

SIGQGAFGRVVKARNTDTT------------TEVACKIVSYEGVK----------------------------DPESMFKESRILKH-------MHHPHI
 .|.|.|| | ..... ||            ..||.||.. . .|                            | .....| .|.|.       ..||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQCYDVIDDKE---------NCT---------LYVFM---ELCES-DL-QRLIDDSKSK--------------KRMVPEAAIWGFLAQAIQALTYLHS
...|.|..|..         . .         .| .|   |.|.  .| ..| |  ...              .. ..|.    .  | ..|. |.||
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHS
Kinase GL50803_95717.AA STE 148-281 23 1.3e-26 91.04 In-house 175-359 (359) Show / Hide 
Range on Protein: 148-281
Range on HMM: 175-359/359
Sequence Identity: 23% (45 aa)

HRDIKPANLLLDKEGNIKLADFNVSTAIKG-----------------DKLNSTKCGTPLYAPPEIHEG-V---REYHGGAVDIWSLGCTIYHVCALRPPF
|||||||| ||     .||.|| |.. .                   .. . | .||| .  ||. ..     .  ..  .||||||||| . .  .||.
HRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPW

VA-VGMGPLIRMIRS--------------GVYPEMPQ-------------------FYSKELHEVIENMIRPKPACRISTADLLQ--HNRI
     |  . .....              |  |  |.                    .|.|... |..  .  |  | .. .||.  |  |
HDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_95717.AA CAMKL 9-127 26 8.1e-26 79.25 In-house 1-145 (297) Show / Hide 
Range on Protein: 9-127
Range on HMM: 1-145/297
Sequence Identity: 26% (38 aa)

YEYIGSIGQGAFGRVVKARNTDTT-TEVACKIVSYEGVK-DPESMFK--------------ESRILKHMH---HPHIVQCYDVIDDKEN----CTLYVFM
|. .  .|.|.|| |  |... || ..|| ||.  .. . || .. .              | .|.|...   ||.|.. |.||...|.      .| .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCESD---LQRLIDDSKSKKRMVPEAAIWGFLAQAIQALTYLHS
|.|..    |.  |.  . ...  ||     .  | . |. |.||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHS
Kinase GL50803_95717.AA Ciliate-E2 145-281 22 3.7e-25 83.28 In-house 181-365 (365) Show / Hide 
Range on Protein: 145-281
Range on HMM: 181-365/365
Sequence Identity: 22% (44 aa)

KVYHRDIKPANLLLDKEGNIKLADFNVSTAIKGD-----------KLNSTK----------------------CGTPLYAPPEIHEGV-------REYHG
.. |||||| |.|.     ||..||  |. .. |           ..   |                      |||| | .|||..|        .....
NIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYD

GAVDIWSLGCTIYHVCALRPPFVAVGMGPLIRMIRSGVYPEMPQF-----------------YSKELHEVIEN----MIRPKPACRIS-TADLLQHNRI
 ..||||||...|  .  .|||        .. |  . .   ...                  |.|    | .    |.  .|  ||.   ..|.|  .
YKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_95717.AA NEK 207-281 36 1.7e-24 83.48 In-house 205-286 (286) Show / Hide 
Range on Protein: 207-281
Range on HMM: 205-286/286
Sequence Identity: 36% (30 aa)

VDIWSLGCTIYHVCAL--RPPFVAV--GMGPLIRMIRSG-VYPEMPQF--YSKELHEVIENMIRPKPACRISTADLLQHNRI
.||||||| .|. |.|  ..|| |    |  |.  |. |  ||  |..  ||..|...|..|... |  | |. ..|..  |
SDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_95717.AA STE 9-127 22 4.4e-24 82.0 In-house 1-170 (359) Show / Hide 
Range on Protein: 9-127
Range on HMM: 1-170/359
Sequence Identity: 22% (39 aa)

YEYIGSIGQGAFGRVVKARNT------DTTTE---------VACKIVSYEGV-----------------KDPESMFKESRILKHMH--HPHIVQCYDVID
.| |. ||.|||| |.||.|       .|  .         .| |....|                   .. ..  || .|.|...  ||.||..|.   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DKENC-----TLYVFMELCE-SDLQRLIDDSKSKKRM----------VPEAAIWGFLAQAIQA-LTYLHS
.. ..     .|...||...   |  .|.  ......          .||  |  .. | ... | ||||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHS
Kinase GL50803_95717.AA STE11 148-281 27 2.1e-23 81.64 In-house 139-303 (303) Show / Hide 
Range on Protein: 148-281
Range on HMM: 139-303/303
Sequence Identity: 27% (46 aa)

HRDIKPANLLLDKEGN-IKLADFNVSTAIKGDKLNSTK-----------CGTPL--------YAPPEIHE-GVREYHGGAVDIWSLGCTIYHVCALRPPF
|||||.||.|||..|| .|||||  .. .... ....             |||         .  ||.   . |. .| ..||||||||..  .  .||.
HRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPW

VAVG---MGPLIRMIRS-GVYPEMPQFYS------KELHEVIENMIRPKPACRISTADLLQHNRI
   .   |  . . ... . .|. |.  |       |... . .   . |  | . ..||||. |
HNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase GL50803_95717.AA NEK2 9-169 27 3.1e-23 74.97 In-house 1-208 (319) Show / Hide 
Range on Protein: 9-169
Range on HMM: 1-208/319
Sequence Identity: 27% (58 aa)

YEYIGSIGQGAFGRVVKARNTDTTTEVACKIVSYEGVKDPE--SMFKESRILKHMHHPHIVQCYDVIDDKENCTLYVFMELCES-DLQRLIDDSKSKKRM
||  ..||.| |||. | |   .    . |   |.     |      |  ||.   || ||. || | |..| |||. || ||  ||  .|   .. .. 
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

VPEAAIWGFLAQAIQALTYLHS-----PFNKKYQDEEGVTHNIGKVYHRDIKPANLLLDKEGN-------------------------------------
 .|  ||. ..|   ||   |           |        . . . ||||||||. || ..|                                     
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--IKLADF
  .|| ||
VVVKLGDF
Kinase GL50803_95717.AA ULK 148-281 26 2.2e-22 75.0 In-house 153-329 (329) Show / Hide 
Range on Protein: 148-281
Range on HMM: 153-329/329
Sequence Identity: 26% (47 aa)

HRDIKPANLLLDKE------------GNIKLADFNVSTAIKGD-----KLNSTK-----CGTPLYAPPEIHEGV--REYHG-GAVDIWSLGCTIYHVCAL
||||||.| |...             | .|.|||  .  .  |      . ...     ||||||  |.| .|   .. ..   .||||||| .|     
HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYG

RPPFVAVGMGPLI-----RMIRSG------VYPEMPQFY--------SKELHEVIENMIRPKPACRISTADLLQHNRI
.|||.|    ...     . |. .      .  . .||.        |.|... |  |.  ..  |||  .|..|  .
KPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_95717.AA ULK 148-281 24 1e-21 73.87 In-house 149-324 (324) Show / Hide 
Range on Protein: 148-281
Range on HMM: 149-324/324
Sequence Identity: 24% (44 aa)

HRDIKPANLLLDK------------EGNIKLADFNVSTAIKGDKLNSTKC----------GTPLYAPPEIHEGV--REYHG-GAVDIWSLGCTIYHVCAL
||||||.|.|. .            .| .|.|||  .  .  . .. ..|          |||||  |.| .|   .. ..   .||||||| .|     
HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYG

RPPFVAVGMGPLI----RMIRSG------VYPEMPQFY--------SKELHEVIENMIRPKPACRISTADLLQHNRI
..||..    ...    ..|. |      .. .  ||.        |.|... |  |.  ..  |||  ....|  .
KYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_95717.AA NEK2 208-281 43 3.6e-21 67.93 In-house 246-319 (319) Show / Hide 
Range on Protein: 208-281
Range on HMM: 246-319/319
Sequence Identity: 43% (32 aa)

DIWSLGCTIYHVCALRPPFVAVGMGPLIRMIRSGVYPEMPQFYSKELHEVIENMIRPKPACRISTADLLQHNRI
||||.|| ||  |||.||| |     |   |. | .   |  ||..| |.|  ||  ..  | |.  .||| .|
DIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMINVDHYHRPSIEEILQHPQI
Kinase GL50803_95717.AA ULK 9-127 25 7.1e-21 69.66 In-house 1-148 (329) Show / Hide 
Range on Protein: 9-127
Range on HMM: 1-148/329
Sequence Identity: 25% (37 aa)

YEYIGSIGQGAFGRVVKARNTDTT----TEVACKIVSYEGVKDPE----------SMFKESRILKHMH--------HPHIVQCYDVIDDKENCTLYVFME
|. .  .|.|.||.| |.|| .|       ||||... .  .  .          .  .| .|.| ..        ||.||. ||.  .. .. .| .||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCES-DLQRLIDDSKS------KKRMVPEAAIWGFLAQAIQALTYLHS
.|.  ||. .|   |       .|.  .|  .  |. | .... .||.
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK
Kinase GL50803_95717.AA ULK 9-127 25 4.2e-20 68.06 In-house 1-144 (324) Show / Hide 
Range on Protein: 9-127
Range on HMM: 1-144/324
Sequence Identity: 25% (37 aa)

YEYIGSIGQGAFG-RVVKARNTDTT---TEVACKIVSYEGVKDPESM----------FKESRILKHMH---HPH--IVQCYDVIDDKENCTLYVFMELCE
|. .  .|.|.||  | |.|| .|      ||||...  . .. ...           .| .|.| ..   ||.  ||. ||.  .. .  .| .||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

S-DLQRLIDDSKS-----KKRMVPEAAIWGFLAQAIQALTYLHS
  ||. .|   |      .|.  .|  . .|. | .... .||.
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHK
Kinase GL50803_95717.AA MARK 9-90 27 2.1e-19 60.26 In-house 1-86 (262) Show / Hide 
Range on Protein: 9-90
Range on HMM: 1-86/262
Sequence Identity: 27% (24 aa)

YEYIGSIGQGAFGRVVKARNTDTTTEVACKIVSYEGVKDPES---MFKESRILKHMHHPHIVQCYDVID--DKENCTLYVFMELCES
|. .  ||.|... | .|... | ..|| ||.  .   ||..    . | .|.|...||.|.....||.  .... ..|. ||....
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQH-QIYLIMEYASG
Kinase GL50803_95717.AA Ciliate-E2 9-127 21 1.3e-17 57.06 In-house 1-178 (365) Show / Hide 
Range on Protein: 9-127
Range on HMM: 1-178/365
Sequence Identity: 21% (38 aa)

YEYIGSIGQGAFGRVVKARNTDTTTEVA--------------------CKIVSYEGVKDPESMFKESRILKHMH----------------HPHIVQCYDV
|. |  ||||.|| | |...  .  ..|                     . . .   .. |....| .|.. ..                ||.|...|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IDDKENCTLYVFMELCES-DLQRLIDDSKSKKRMVPE-------AAIWGFLAQAIQ---------------ALTYLHS
  .| . ..|  ||.|.  ||. .| ..| |.   .|         |  . .| .|               || ||||
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHS
Kinase GL50803_95717.AA STE11 15-89 28 5.5e-15 50.88 In-house 7-96 (303) Show / Hide 
Range on Protein: 15-89
Range on HMM: 7-96/303
Sequence Identity: 28% (26 aa)

IGQGAFGRVVKARNTDTTTEVACKIVSYEGVK--------DPES------MFKESRILKHMHHPHIVQCYDVIDDK-ENCTLYVFMELCE
||.||||.| |..|.|| ...| | . ... .          .|        .| ...||..|..||. |..  .. .| ....||| |.
IGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCP
Kinase GL50803_95717.AA Pkinase_Tyr 9-89 31 3.7e-13 45.2 Pfam 1-90 (270) Show / Hide 
Range on Protein: 9-89
Range on HMM: 1-90/270
Sequence Identity: 31% (29 aa)

YEYIGSIGQGAFGRVVKARNT----DTTTEVACKIVSYEGVKDP----ESMFKESRILKHM-HHPHIVQCYDVID-DKE-NCTLYVFMELCE
 . .  .|.||||.|.|.. .    .|...|| |..  ||  ..    |....| .|.|.. |||.||..| |.  ..| |  .|. ||...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMP
Kinase GL50803_95717.AA TyrKc 9-281 19 5.4e-13 -12.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-281
Range on HMM: 1-280/280
Sequence Identity: 19% (61 aa)

YEYIGSIGQGAFGRVVKARNTDTTTEVACKIVSYEGVKDPESMFKESRILKHM--HHPHIVQCY-DVIDDKEN----CTLYVFMELCES-DLQRLIDDSK
 . .  .| ||||.|.|.. .   ..|| | .  .     | . .| ||...   |||.||..|  ......|      |.. ||...  ||.  . ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

SKKRMVPEAAIWGFLAQAIQALTYLHSPFNKKYQDEEGVTHNIGKVYHRDIKPANLLLDKEGNIKLADFNVSTAIKGD-------KLNSTK---CGTPL-
 |   .. .    |  |. .   ||||                 .. |||.   | |..... .| .||  | .|. |       .  ..|   .|  . 
PK---LCMKDLLSFCWQIACGMEYLHSK----------------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTML

---YAPPEIHEGVREYH--GGAVDIWSLGCTIYHVCAL-RPPFVA-----VGMGPLIRMIRSGVYPEMPQF--------YSKELHEVIENMIRPKPACRI
     .||       |.    . |.|| | ... .. .  .|        .    .|. ...| ... |.          ..|......   . .|..| 
PIRWMAPECI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP

STADLLQHNRI
. ...  | ..
TFSEI--HECF
Ank GL50803_95717.AA Ank 674-700 37 0.213068 9.3 Pfam 1-26 (33) Show / Hide 
Range on Protein: 674-700
Range on HMM: 1-26/33
Sequence Identity: 37% (10 aa)

EGNTRLIRACKRSSYTDAISNLVQAGA
.|.| |  ||..  .|. .. |.|.||
DGFTPLHLACRCG-HTEVVKMLLQHGA
Ank GL50803_95717.AA Ank 704-731 21 0.004804 15.24 Pfam 1-28 (33) Show / Hide 
Range on Protein: 704-731
Range on HMM: 1-28/33
Sequence Identity: 21% (6 aa)

KGETALLWAAFFNNSDLCRLLVDKEAKL
 |.|.| .|.. .. . ...|... | .
DGFTPLHLACRCGHTEVVKMLLQHGADV
Ank GL50803_95717.AA Ank 735-758 41 0.000925 17.82 Pfam 1-24 (33) Show / Hide 
Range on Protein: 735-758
Range on HMM: 1-24/33
Sequence Identity: 41% (10 aa)

DGTTALMKAAGHGSTSTVELLLNY
|| |.|. |. .|.|. |..||..
DGFTPLHLACRCGHTEVVKMLLQH
Ank GL50803_95717.AA Ank 766-786 42 0.002704 16.14 Pfam 1-21 (33) Show / Hide 
Range on Protein: 766-786
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

DGLTALMFATMNHHTKCVELL
|| |.|. | .. ||..|..|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_95717.AA Ank 797-817 42 0.054695 11.43 Pfam 1-21 (33) Show / Hide 
Range on Protein: 797-817
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

DGSTSLIMAATRGYDDIVKIL
|| | | .|. .|. ..|| |
DGFTPLHLACRCGHTEVVKML
Ank GL50803_95717.AA Ank 828-851 37 0.006912 14.67 Pfam 1-24 (33) Show / Hide 
Range on Protein: 828-851
Range on HMM: 1-24/33
Sequence Identity: 37% (9 aa)

DGKTALMEASLQGKLACAKILCQY
|| |.|. |.. | . ..| | |.
DGFTPLHLACRCGHTEVVKMLLQH
Ank GL50803_95717.AA Ank 859-879 38 0.018476 13.13 Pfam 1-21 (33) Show / Hide 
Range on Protein: 859-879
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

DGKTALIFAASKGNPALVQLL
|| |.|  |...|..  |..|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_95717.AA Ank 921-941 33 0.000227 20.02 Pfam 1-21 (33) Show / Hide 
Range on Protein: 921-941
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

DGRTALMIAATYNRAECCEVL
||.|.|..|. ....|... |
DGFTPLHLACRCGHTEVVKML
Ank GL50803_95717.AA Ank 890-920 36 0.002995 15.98 Pfam 1-33 (33) Show / Hide 
Range on Protein: 890-920
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

RSYTGLMYAAMNGHPEVCKILLG--AEHGSCDK
  .| |..|...||.||.| ||.  |.    |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_95717.AA Ank 980-1000 38 9.446981 3.36 Pfam 1-21 (33) Show / Hide 
Range on Protein: 980-1000
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

YGLEALDVALREGHKDIVDEL
.|  .| .| | ||...| .|
DGFTPLHLACRCGHTEVVKML