Gene GL50803_9196 (G.lamblia)

GL50803_9196

Species: G.lamblia
Alias: GK164, GL50803_9196
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_9196.AA Protein None 297 None Fasta, JSON
GL50803_9196.kin_dom Protein Kinase Domain None 268 None Fasta, JSON

Protein domain

Protein domains of GL50803_9196.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_9196.AA S_TKc 14-281 23 1.3e-43 152.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-281
Range on HMM: 1-231/231
Sequence Identity: 23% (67 aa)

IDDKMLIGEGTFGNVYLVRTLAGDQQRALKVIDMQRAPERYKPSSYSDLENLTSMVHQNLVRYHDVFYDSQENKAYLVMDYHER--CCLADIIVFYHSHK
 .   .||.|.|| ||..|    ... |.|.|.          . .. .. | .  | |.|...|||.|   .. |.||.| .     | |.|. . .|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

KY--IPESVVWRVLAHMMAALCYYHTPFKSGASHMGRMVHRDIKPANIFLAADGYCKLVD---SASFRLLDKTTINSTIFGTLGYCSPEVLKMEQYSD-K
..  .|| ....... .  || |          |  . .|||.||.||.|      |. |   .. .         .|. ||. |..||||   .|.  |
LRFPFPE-HARFYMYQICCALEY---------CHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCK

SDIWALGATIYAMCMQRPLCKETDPEKQREAISSIESIDITSAGYSTQLNTILNFMLASNPAKRFSASDLYS-------FPAL
.|.|..| ..| |.  .|.    ....  . |             | ..  ... .|  .|.|| .| ..          | .
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_9196.AA STE 14-281 19 5.2e-34 117.52 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-281
Range on HMM: 1-359/359
Sequence Identity: 19% (72 aa)

IDDKMLIGEGTFGNVYLVRTL------AGDQQ---------RALKVIDMQRAP---------------ERYKPSSYSDLENLTSMV--HQNLVRYHDVFY
 ..   ||.|.|| ||. .          ...          | |......                 .  . .   ... .  .   |.| |.|.. ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----DSQENKAYLVMDYHERCCLADIIVFYHSHKK----------YIPESVVWRVLAHMMAA-LCYYHTPFKSGASHMGRMVHRDIKPANIFLAADGYC
     ...... ...| | .  .| |||  .....|          ..|||.. ...     . | | |       ||    .|||||||||.|     .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLH-------SHH--IIHRDIKPANILL-----V

KLVD-SASFRLLDKTT----------------INSTIFGTLGYCSPEVLKM------EQYSDKSDIWALGATIYAMCMQRPLCKETDPEKQREAISSI--
||.|   . .| |. .                 . |. ||  . .|||..        .|. |.||| || ||  |.  .| . .  | .   .|     
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH

-------------ESIDITS------------------AGYSTQLNTILNFMLASNPAKRFSASDLYS--FPAL
             ..  . .                    .|  ..  .|  |  .| || .||.| .   | .
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_9196.AA NEK 11-223 31 9.7e-33 112.82 In-house 1-224 (286) Show / Hide 
Range on Protein: 11-223
Range on HMM: 1-224/286
Sequence Identity: 31% (74 aa)

YTEIDDKMLIGEGTFGNVYLVRTLAGDQQ-----RALKVIDMQRAPERYKPSSY-SDLENLTSMVHQNLVRYHDVFYDSQENKAYLVMDYHE-RCCLADI
|..|     ||.| || ||.||     ..      ..| |.|..  |. |  .. .    | .. |.| |.|.| |.. | |. . ||.| |    |.. 
YEIIK---KIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQK

---IVFYHSHKKYIPESVVWRVLAHMMAALCYYHTPFKSGASHMGRMVHRDIKPANIFLAADGY----CKLVD--SASFRLLDKTTI-NST-IFGTLGYC
   |  .   .||..|...|.....|  || | |     .    .. .||||||.|||| ...      |. |   .  ..|..||   .|   ||  | 
IKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRK-GP---QRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGIS--KVLNHTTDMAYTTQVGTPYYM

SPEVLKMEQYSDKSDIWALGATIYAMCMQ--RP
||||.. . |. |||||.||  .| ||..  ..
SPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKH
Kinase GL50803_9196.AA Ciliate-E2-Unclassified 14-281 18 4e-32 108.72 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-281
Range on HMM: 1-352/352
Sequence Identity: 18% (65 aa)

IDDKMLIGEGTFGNVYLVRTLAGDQQ----RALKVIDMQ----RAPERYKPSSYSDLENL--------------TSMVHQNLVRYHDVFYDSQENKAYLV
      ||.| || ||...    .|.     . |...      .  .  .  .   ..|.                  |............ .... |.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MDYHERCCLADIIVFYHS-------------HKKYIPESVVW-----RVLAHMMAALCYYHTPFKSGASHMGRMVHRDIKPANIFLAADG---YCKLVDS
|.| |   | ..|  ...             ..| ..|  .      . .|.   .|.|.|        | .  .|||||| ||..  .|   |.|. | 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLH--------HKNNIIHRDIKPENILFDNNGKNYYIKIIDF

ASFRLLD----------------KTTINSTIFGTLGYC----SPEVLKMEQYSDK----SDIWALGATIYAMCMQRPLCKETDPEK--------------
 ... ..                |  . .|. ||..|     .||||. ..|...    .|||.||  .|.|.....  . .. |.              
GISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYR

--QREAI-SSIESIDITS-----AGYSTQLNTILN----FMLASNPAKRFSASDLYSFPAL
  ... |   . ...  .      . | .   ..|     ||  || || .....   | .
KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_9196.AA Pkinase 14-281 21 1.2e-29 105.88 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-281
Range on HMM: 1-293/293
Sequence Identity: 21% (66 aa)

IDDKMLIGEGTFGNVYLVRTLAGDQQRALKVIDMQRAPERYKPSSYS--DLENLTSMVHQNLVRYHDVFYDSQENKAYLVMDYHERC----CLADIIVFY
.  .  ||.|.|| ||. .     .. |.|.|. ... .  . .      .. . .. | | ||..|.|.|  ... |.||.|.|       |.|.|   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST-

HSHKKYI--PESVVWRVLAHMMAALCYYHTPFKSGASHMGRMVHRDIKPANIFLAADGYC----KLVD---SASFRLLDKTTINSTIFGTLGYCSPEVLK
 . .. .  .| .. ...  .  .| | |           . .|||.||.||..  .|..    |. |   .. |. . . . ..|. ||..|..|||..
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR

-MEQYSDKSDIWALGATIYAMCMQRPLCKET----DPEKQREAISSIESIDITSAGY----------------------STQLNTILNFMLASNPAKRFS
  . |. |.|.|..| ..| |.  ||....     .   |.. |  | . .. .  .                      |  .  ... .|. .|.|| .
GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

ASDLYSFPAL
| ..   | .
AEQILQHPWF
Kinase GL50803_9196.AA NEK6 13-218 32 7.5e-27 85.21 In-house 2-196 (252) Show / Hide 
Range on Protein: 13-218
Range on HMM: 2-196/252
Sequence Identity: 32% (69 aa)

EIDDKMLIGEGTFGNVYLVRTLAGDQQRALK---VIDMQRAPERYKPSSYSDLENLTSMVHQNLVRYHDVFYDSQENKAYLVMDYHERCCLADIIVFYHS
.|. |  || | |  ||  . |  |.. |||   . .|  |  |       ||  | .. |.|...| . | .  .|.  .|..  .   .. .| ..  
QIEKK--IGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDL--LKQLNHPNVIKYYASFIE--NNELNIVLELADAGDMSRMIKHFKK

HKKYIPESVVWRVLAHMMAALCYYHTPFKSGASHMGRMVHRDIKPANIFLAADGYCKLVDSASFRLL-DKTTINSTIFGTLGYCSPEVLKMEQYSDKSDI
 |. |||  .|.    .  ||            |  |..||||||||.|. |.|  || |    |    |||    . ||  | ||| .. . |  ||||
QKRLIPERTIWKYFVQLCSALEHM---------HSKRVMHRDIKPANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDI

WALGATIYAM
|.||  .| |
WSLGCLLYEM
Kinase GL50803_9196.AA Ciliate-E2 148-281 20 2e-22 73.78 In-house 183-365 (365) Show / Hide 
Range on Protein: 148-281
Range on HMM: 183-365/365
Sequence Identity: 20% (40 aa)

VHRDIKPANIFLAADGYCKLVDSASFRLLDKTTINST--------------------------------IFGTLGYCSPEVLKMEQ---------YSDKS
.|||||| ||..     .|..|    . .|.  .| |                                | ||.|| .||.|....         |. |.
IHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKC

DIWALGATIYAMCMQRPLCKETDPEKQREAISSIESIDITSA-----------------GYSTQLNTILNF----MLASNPAKRFS-ASDLYSFPAL
|||.|| ..| |.. .|           . .     ||. ..                   | .   ...     ||  .| ||.. ....   | .
DIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_9196.AA NEK10 13-223 28 1.1e-21 68.01 In-house 2-218 (279) Show / Hide 
Range on Protein: 13-223
Range on HMM: 2-218/279
Sequence Identity: 28% (66 aa)

EIDDKMLIGEGTFGNVYLVRTLAGDQ------QRALKVIDMQR-APERYKPSSYSDLENLTS--------MVHQNLVRYHDVFYDSQENKAYLVMDYHER
|. |..  | | || || ||  |.          |.| | |.  |  . .  . . .|.. |        | | | |||  .|   | .. | ||.  | 
EVYDHL--GTGAFGCVYKVRKKAQQHSENPAKLLAMKEIFMHNPAFGKNDKERDKSIEDMISELKIIKEQMRHPNIVRYYRTFVEPQNHRMYIVMELIEG

CCLADIIVFYHSHKKYIPESVVWRVLAHMMAALCYYHTPFKSGASHMGRMVHRDIKPANIFLAADGYCKLVDS--ASFRLLDKTTINSTIFGTLGYCSPE
| | . .      ..   |  .|...  |. || | |           . |||| .| || .  .      |   |  .  |   . | . ||  |  ||
CPLYEHFNSMKEKHHHFEEERIWHMFIQMCLALRYLH--------KEKQIVHRDLTPNNIMMGDKDRVTITDFGLAKQKQPDPSKMTSVV-GTILYSCPE

VLKMEQYSDKSDIWALGATIYAMCMQRP
... | |  | |.|| |  .| ||  .|
IVQSEPYGEKADVWAFGCCLYQMCTLQP
Kinase GL50803_9196.AA NEK2 70-163 30 3.2e-19 61.28 In-house 57-162 (319) Show / Hide 
Range on Protein: 70-163
Range on HMM: 57-162/319
Sequence Identity: 30% (34 aa)

HQNLVRYHDVFYDSQENKAYLVMDYHERCCLADIIVFYHSHKKYIPESVVWRVLAHMMAALCYYHT----------------PFKSGASHMGRMVHRDIK
|.| ||| |   | |.   |.|| | |.  |. .|  . . ..|..|...||... .  ||   |                 . . .    .   |||||
HPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQYMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGK----HTILHRDIK

PANIFLAADG
|||||| .|.
PANIFLDYDH
Kinase GL50803_9196.AA STE20 14-212 24 8.3e-19 65.6 In-house 1-214 (288) Show / Hide 
Range on Protein: 14-212
Range on HMM: 1-214/288
Sequence Identity: 24% (55 aa)

IDDKMLIGEGTFGNVYLVRTLAGDQQ----RALKVIDMQRA-PERYKPSSYSDLEN----LTSMVHQNLVRYHDVFYDSQE--NKAYLVMDYHERCCLAD
 ..   ||.|..| ||...    ...     | |....  . .|.    .  |...    .    |.| |.|.. .. . .  .. ..||.| .  .| |
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ---DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTD

IIVFYHSHKK-----YIPESVVWRVLAHMMAALCYYHTPFKSGASHMGRMVHRDIKPANIFLAADGYCKLVDSASFR---LLDK----TTI--NSTIFGT
|. .. ...|      . |. .  ..  .  .| | |           ...||||| .|| |  || .||.|   |     |.|    |      |. ||
IMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHS---------NHIIHRDIKADNILLTEDGEVKLAD---FGVCAQLTKHGRDTMQFKRNTFVGT

LGYCSPEVLKM-----EQYSDKSDIWALG
  . .|||..       .|  |.|||.||
PYWMAPEVIQCMEGPDKGYDYKCDIWSLG
Kinase GL50803_9196.AA CAMK 19-132 13 5e-13 37.61 In-house 1-194 (425) Show / Hide 
Range on Protein: 19-132
Range on HMM: 1-194/425
Sequence Identity: 13% (27 aa)

LIGEGTFGNVYLVRTLAGD------------QQRALKVIDMQRAPE-------------------------RYKPSSYSDLENLTSMV--------HQNL
 .|.|.|| |.|..                 |. | |.|| .....                          ..  .     .. ...        | |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYHDVFYDSQ-----------------ENKAYLVM---DYHERCCL----ADIIVFYHSHK-----------KYIPESVVWRVLAHMMAALCY
.. ..|. |..                 ... |.||   .| .  .|     | ||   .             ....|. . |.   .  |. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHY
Kinase GL50803_9196.AA CAMK 148-218 22 2.4e-12 35.38 In-house 201-327 (425) Show / Hide 
Range on Protein: 148-218
Range on HMM: 201-327/425
Sequence Identity: 22% (28 aa)

VHRDIKPANIFLAADG----------------Y-CKLVDSASFRLLDKTTINS------------------------TIFGTLGYCS-PEVLKM------
||||.|| || |  ..                .  |..|    . .|.   |                         | .||..|.. ||||.       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EQYSDKSDIWALGATIYAM
        . |. |.|.|..|   |.|
QNATDEEKPYYGPKCDMWSCGVILYIM
Kinase GL50803_9196.AA ULK 148-281 19 6.9e-12 38.52 In-house 148-324 (324) Show / Hide 
Range on Protein: 148-281
Range on HMM: 148-324/324
Sequence Identity: 19% (35 aa)

VHRDIKPANIFLAAD------------GYCKLVDSASFRLLDKTTINSTIF----------GTLGYCSPEVLK----MEQYSDK-SDIWALGATIYAMCM
.||||||.|| .  .            | .|. |    . .|. . . ...          ||  | .|..|.     ..|.|. .||| ||  .| |  
IHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLY

QR-P----LCKETDPEKQREA---------ISSIESIDITSA---GYSTQLNTILNFMLASNPAKRFSASDLYSFPAL
 . |     ... .  .|..          |                | ..  ..  ||  .. .|.|  .... | .
GKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_9196.AA Ciliate-E2 14-94 19 2.8e-11 34.97 In-house 1-115 (365) Show / Hide 
Range on Protein: 14-94
Range on HMM: 1-115/365
Sequence Identity: 19% (22 aa)

IDDKMLIGEGTFGNVYLVRTLAGDQQRALK--------------VIDMQRAPERYKPSSYSDLENLTSMV--------------------HQNLVRYHDV
..   .||.|.|| ||...    ..| |.|              |  .. | ...|..    ...  ..                     | |.......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FYDSQENKAYLVMDY
|.. ..|. ||||.|
FQEKDDNNIYLVMEY
Kinase GL50803_9196.AA NEK2 191-219 51 8e-10 29.13 In-house 230-258 (319) Show / Hide 
Range on Protein: 191-219
Range on HMM: 230-258/319
Sequence Identity: 51% (15 aa)

YCSPEVLKMEQYSDKSDIWALGATIYAMC
| |||...   |..|||||..|  || ||
YMSPEQMHGQKYNEKSDIWSVGCLIYEMC
Kinase GL50803_9196.AA ULK 14-94 23 1.7e-09 29.91 In-house 1-98 (324) Show / Hide 
Range on Protein: 14-94
Range on HMM: 1-98/324
Sequence Identity: 23% (23 aa)

IDDKMLIGEGTFG-NVYLVRTLAG---DQQRALKVID---MQRAPERY-----KPSSYSDLENLTSMV---HQN--LVRYHDVFYDSQENKAYLVMDY
.  .  .|.|.||  ||  |       .|. | |.||   |.  . ..     . .  .  ...  .    |.|   |...|.|..|..|  |..|.|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEY
Kinase GL50803_9196.AA NEK 250-281 28 2.4e-07 22.35 In-house 255-286 (286) Show / Hide 
Range on Protein: 250-281
Range on HMM: 255-286/286
Sequence Identity: 28% (9 aa)

YSTQLNTILNFMLASNPAKRFSASDLYSFPAL
||..|. ....||  .| .| |.... ..| .
YSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_9196.AA TyrKc 14-279 14 2.7e-07 -104.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-279
Range on HMM: 1-280/280
Sequence Identity: 14% (46 aa)

IDDKMLIGEGTFGNVYLVRTLAGDQQRALKVIDMQRAPERYKPSSYSDLEN----LTSM--VHQNLVRYHDVFYDSQE-----NKAYLVMDYHERCCLAD
|  .  .||| || ||. .     .| | |..               |. .    ...    |.|.|| . |  ....        ..|| | .  .| |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

IIVFYHSHKKYIPESVVWRVLAHMM----AALCYYHTPFKSGASHMGRMVHRDIKPANIFLAADGYCKLVDSASFRLLDKT--------TIN-----STI
 .  .. .       . .. | ...    .   | |           . .|||.   |. ..... .|  |    | ..          ..      .. 
YLRKHRPK-------LCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

F-GTLGYCSPEVLKMEQYSDKSDIWALGATIYAMCMQRPLCKETDPE------KQREAISSIESIDITSAGYS-------TQLNTILNFML---ASNPAK
.   .  ..||...   .. |||.|. | ... ..    ....  |.      . .|.|  ... .      .       .    . . |.   . .|..
TMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFT---YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPED

RFSASDLYSFP
| . |..... 
RPTFSEIHECF
Kinase GL50803_9196.AA NEK2 250-281 31 0.011519 4.66 In-house 288-319 (319) Show / Hide 
Range on Protein: 250-281
Range on HMM: 288-319/319
Sequence Identity: 31% (10 aa)

YSTQLNTILNFMLASNPAKRFSASDLYSFPAL
||. || |  ||.. .. .| |   .   | .
YSRHLNEIIHFMINVDHYHRPSIEEILQHPQI
Kinase GL50803_9196.AA STE20 250-281 28 0.118025 2.18 In-house 257-288 (288) Show / Hide 
Range on Protein: 250-281
Range on HMM: 257-288/288
Sequence Identity: 28% (9 aa)

YSTQLNTILNFMLASNPAKRFSASDLYSFPAL
.|....  .. .|  .|.|| .||.| . | .
WSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI