Gene GL50803_8350 (G.lamblia)

GL50803_8350

Species: G.lamblia
Alias: GL50803_8350, GK168
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_8350.AA Protein None 617 None Fasta, JSON
GL50803_8350.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of GL50803_8350.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_8350.AA S_TKc 11-279 30 7.4e-75 255.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 11-279
Range on HMM: 1-231/231
Sequence Identity: 30% (87 aa)

YEILDVIGQGGFGKVYKVRYIPTEALYAYKLISYANETSEVQGLIESEIKLTRHLSHPNIIKFHHVYHSEERKEYHIIMDLCEG--GDLRQFIDKRQR--
||||..||.|.||||||.| . |  ..| | |.           |..||.. ..  ||||.|.. |...   ......|..|.|  |||...|.||.|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

MQTSLEEELIWLYMGQILLALAYLHCPFKSGIQQHGRIIHRDIKPANIFIKGSNTLIVGDLGICKDIGRHSSTDAKIGTPAYMAPEVLMNVKQGYNE-KS
 .  . |  .. || ||..||.|.|        .| .|||||.||.||..    .. ..| |... .      .  .||| |||||||     ||.  |.
LRFPFPE-HARFYMYQICCALEYCH--------SH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-----GYGKCKC

DIWSLGLIVYELCTFERLVSGATVADAIESIEYINFPIIVEGYSLELVEVINGMIDPNIMTRFSAHDLLA-------HPRL
|.||.| |.||... . . .  ...  .. |            | |. . |... . .   | .| ..|.       || .
DWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase GL50803_8350.AA Pkinase 11-279 27 4e-67 234.1 Pfam 1-293 (293) Show / Hide 
Range on Protein: 11-279
Range on HMM: 1-293/293
Sequence Identity: 27% (85 aa)

YEILDVIGQGGFGKVYKVRYIPTEALYAYKLISYANETSEVQGLIES--EIKLTRHLSHPNIIKFHHVYHSEERKEYHIIMDLCEGG----DLRQFIDKR
|.|. .||.|.||.||| . . |. ..| | |.. .| |...       ||.. ..|.||||.........  .......|..||||    ||  .|   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST-

QRMQTSL--EEELIWLYMGQILLALAYLHCPFKSGIQQHGRIIHRDIKPANIFIKGSNTL----IVGDLGICKD--IGRHSSTDAKIGTPAYMAPEVLMN
 ......  .|. .  || ||| .|.|.|           .|||||.||.||.|.  ...     ..| |..|   . . | ..   ||| ||||||.. 
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-

VKQGYNEKSDIWSLGLIVYELCTFERLVSGA----TVADAIESIEYINFPIIVEGYS-----------------------LELVEVINGMIDPNIMTRFS
  |.|  |.|.||.|.|.||... . . .|.    . .| .. |. |  |.. . ..                        |. ..|.......   | .
GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

AHDLLAHPRL
|...| || .
AEQILQHPWF
Kinase GL50803_8350.AA NEK 11-222 37 2.1e-65 223.57 In-house 1-224 (286) Show / Hide 
Range on Protein: 11-222
Range on HMM: 1-224/286
Sequence Identity: 37% (88 aa)

YEILDVIGQGGFGKVYKVRYIPTEAL-----YAYKLISYANETSEVQGLIE-SEIKLTRHLSHPNIIKFHHVYHSEERKEYHIIMDLCE-GGDLRQF---
|||. .|||| |||||||| . ..       |. | |.. | ... .     .|... ..| ||||.|..  .  |.    .|.|. || |||| |.   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IDKRQRMQTSLEEELIWLYMGQILLALAYLH---CPFKSGIQQHGRIIHRDIKPANIFIKGSNT----LIVGDLGICKDIGRHSS-TDA-KIGTPAYMAP
| |..   . .||| || .. |..||| |.|    |        ..|.||||||.|||.  .|.    . .||.|| |  .. ..      .||| ||.|
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGP-------QRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSP

EVLMNVKQGYNEKSDIWSLGLIVYELCTF--ER
||.    ..||.|||||||| ..||.||.  ..
EVCQ--NKPYNNKSDIWSLGCVLYEMCTLKPKH
Kinase GL50803_8350.AA Ciliate-E2 11-279 23 3.2e-61 208.89 In-house 1-365 (365) Show / Hide 
Range on Protein: 11-279
Range on HMM: 1-365/365
Sequence Identity: 23% (90 aa)

YEILDVIGQGGFGKVYKVRYIPTEALYAYKLISYAN------------ETSEVQGL-------IESEIKLTR----------------HLSHPNIIKFHH
|... .||||.||.|||.. . .  ..|.|.|   .               ..  .       |..||.. |                .|.||||||.. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VYHSEERKEYHIIMDLCEGGDLRQFIDKRQRMQT-------SLEEELIWLYMGQILL---------------ALAYLHCPFKSGIQQHGRIIHRDIKPAN
.. .. .. . ..|..|.||||...| ...  ..       .. |. |  .| |||                || |||        . ..|||||||| |
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLH--------SKNNIIHRDIKPEN

IFIKGSNTLIVGDLGICKDIG-----------RHSSTDAK----------------------IGTPAYMAPEVLMNVK-------QGYNEKSDIWSLGLI
|..     . . |.|..|..            .   .. |                      .||| |||||.|.. |       .||..|.|||||| |
ILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVI

VYELCTFERLVSGATVADAIESIE--YINFPII---------------VEGYSLELVEVING----MIDPNIMTRFS-AHDLLAHPRL
 ||... ..          .. |.   |.||                  .  |.|    |.     |.. .   |.. . ..| || .
LYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_8350.AA STE 11-279 23 2.2e-58 200.3 In-house 1-359 (359) Show / Hide 
Range on Protein: 11-279
Range on HMM: 1-359/359
Sequence Identity: 23% (89 aa)

YEILDVIGQGGFGKVYKVRYI------PTEAL---------YAYKLISYANETS---------------EVQGLIESEIKLTRHLS--HPNIIKFHHVYH
.|....||.|.||.||| ...      .|  .         .| | ... |...               | .  |. |||. ....  ||||.|..  | 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SE-----ERKEYHIIMDLCEGGDLRQFIDKRQRMQTSLE----------EELIWLYMGQILLA-LAYLHCPFKSGIQQHGRIIHRDIKPANIFIKGSNTL
 |     .. | .|.| ...|| |...|...  .. .|           |..|  .  ||| . |.|||        .|. |||||||||||..      
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLH--------SHH-IIHRDIKPANILL-----V

IVGDLGICKDIGRH-----------------SSTDAKIGTPAYMAPEVLMN--VK--QGYNEKSDIWSLGLIVYELCTFERLVSGATVADAIESIEYI--
   | |.|. .  .                 . ..  .||| .|||||...   .  .||..|.||||||. . |..| .   .  .   |.  |     
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH

-------------NFPIIVE-------------------GYSLELVEVINGMIDPNIMTRFSAHDLLA--HPRL
             . | . .                    .| |. . ||   . .   | .|..||   || .
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_8350.AA Ciliate-E2-Unclassified 11-279 22 4.3e-54 186.03 In-house 1-352 (352) Show / Hide 
Range on Protein: 11-279
Range on HMM: 1-352/352
Sequence Identity: 22% (83 aa)

YEILDVIGQGGFGKVYKVRYIPTEALY-----AYKLISYA-NETSEVQGLIESEIKLTRH----------------LSHPNIIKFHHVYHSEERKEYHII
|.|. .|||||||||||.. . .  .|     . | ..|. .   ... .. ... . ..                |.||.... . .|. . ..   |.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MDLCEGGDLRQFIDKR-----------QRMQT--SLEEELIW-----LYMGQILLALAYLHCPFKSGIQQHGRIIHRDIKPANIFIKGSN---TLIVGDL
|..||||||.|.| ||           ..|..   ..|. .       |. |||..| |||       ...  |||||||| ||... ..    . . |.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLH-------HKN-NIIHRDIKPENILFDNNGKNYYIKIIDF

GICKDIG----------------RHSSTDAKIGTPAYM----APEVLMNVKQGYN--EKSDIWSLGLIVYELCTFERLVSGATVAD--------------
||.| ..                ..  .. ..||| ||    |||||.. ...    .|.|||||| | ||... ..  .. .  .              
GISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYR

-AIESIEYIN-----------FPIIVEGYSLELVE-VINGMIDPNIMTRFSAHDLLAHPRL
  .... . .           .| ..     ....  .  |.. |.  | .. ..| || .
KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_8350.AA CAMK 16-215 20 5.4e-49 155.59 In-house 1-325 (425) Show / Hide 
Range on Protein: 16-215
Range on HMM: 1-325/425
Sequence Identity: 20% (67 aa)

VIGQGGFGKVYKVRYIPTE------------ALYAYKLISYANET--------------------------SEVQGLIESEIKLTRHLS-------HPNI
..|.|.||||.... . |               .| | |.    .                           . .  ...||.. ..|.       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKFHHVYHSEE-----------------RKEYHIIM---DLCEGG----DLRQFIDKR------------QRMQTSLEEELIWLYMGQILLALAYLHCPF
||...|| ...                 .|.....|   ..|.||    || ..| ..              .   ..|.    |. ||. |..|.|   
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCH---

KSGIQQHGRIIHRDIKPANIFIKGS-----------------NTLIVGDLGICKDIGR------------------------HSSTDAKIGTPAYMA-PE
     .|. |.|||.|| || .  .                 |.. . | |  . . .                                |||.||| ||
-----SHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE

VLMNV------------KQGYNEKSDIWSLGLIVY
||               |..|..|.|.||.| | |
VLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY
Kinase GL50803_8350.AA ULK 11-219 30 1.1e-48 168.02 In-house 1-251 (329) Show / Hide 
Range on Protein: 11-219
Range on HMM: 1-251/329
Sequence Identity: 30% (79 aa)

YEILDVIGQGGFGKVYKVRYIPTE----ALYAYKLIS---YANETSEVQ-----GLIESEIKLTRHLS--------HPNIIKFHHVYHSEERKEYHIIMD
|.. ...|.| |||||| | . |.     ..| | |.     ..  | .      |...|||. . |         ||||.|..... .   . . |||.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCEGGDLRQFIDKRQR--MQT----SLEEELIWLYMGQILLALAYLHCPFKSGIQQHGRIIHRDIKPANIFIKGSN------------TLIVGDLGICKD
.|.||||.|.| |...  ..|     |.|. .  .. ||| .. .||        .|. ||||||||.|| |.  .            .| ..| | .| 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELH--------KHN-IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKH

IGRH----SSTDAKI------GTPAYMAPEVLMNV--KQGYN-EKSDIWSLGLIVYELCT
.         . .        ||| ||||..|..   .. |.  |.|||||| | ||. .
VDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLY
Kinase GL50803_8350.AA ULK 11-219 29 3.3e-48 166.47 In-house 1-247 (324) Show / Hide 
Range on Protein: 11-219
Range on HMM: 1-247/324
Sequence Identity: 29% (76 aa)

YEILDVIGQGGFG-KVYKVRYIPTE---ALYAYKLIS---YANETSEVQ-----GLIESEIKLTRHLS---HPN--IIKFHHVYHSEERKEYHIIMDLCE
|.. ...|.| || |||| | . |.    ..| | |.     .  .| .      |...||.. . |    |||  |.|..... .   . . |||..|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLRQFIDKRQR-----MQTSLEEELIWLYMGQILLALAYLHCPFKSGIQQHGRIIHRDIKPANIFIKGSN------------TLIVGDLGICKDIGRH
||||.|.| |...      .  |.|. .  .. ||. .. .||        .|. ||||||||.|| |.  .            .| ..| | .| .   
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELH--------KHN-IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNN

SSTDAKI----------GTPAYMAPEVLMNV--KQGYN-EKSDIWSLGLIVYELCT
.  . ..          ||| ||||..|..   .. |.  |.|||||| | ||. .
NMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLY
Kinase GL50803_8350.AA CAMK-Unique 11-217 22 2.5e-47 154.18 In-house 1-286 (363) Show / Hide 
Range on Protein: 11-217
Range on HMM: 1-286/363
Sequence Identity: 22% (67 aa)

YEILDVIGQGGFGKVYKVRYIPTEALYAYKLISYANETSEVQGL------------------IESEIKLTRHLSHPNIIKFHHV----YHSEER------
|. . .||.|.||.||..  . |. ..| |..  .   ...| .                   . |. . . ..||||||. ..    .. ..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

-------KEYHIIMDLCEGGDLRQFIDKR----------------QRMQTSLEE--ELIWLYMGQILLALAYLHCPFKSGIQQHGRIIHRDIKPANIFIK
        ...|.|..|.|||| . |.|.                .|.|....|   .. ..| ..| |.||.|            |.|||.|. || ..
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMH---------SQDIVHRDLKLENIMVC

GS----------------NTLIVGDLGICKDIGRHSSTD---AKIGTPAYMAP--------------EVLMNVKQGYNEKS----DIWSLGLIVYEL
 |                . . . | |.|...    .     . .||| ||||              ||...  |.| ...    |||||| | |..
YSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINM--QCYDQQCSPASDIWSLGVIMYYM
Kinase GL50803_8350.AA TKL 17-219 20 2.9e-46 160.01 In-house 1-284 (364) Show / Hide 
Range on Protein: 17-219
Range on HMM: 1-284/364
Sequence Identity: 20% (61 aa)

IGQGGFGKVYKVRYIPTE--------ALYAYKLISY-------------------------ANETSEVQGLIESEIKLTRHLSHPNIIKFHHVYHSEE--
||.||||.||| ..  .            | | ..                          ..|.|  .  .| ||.. . |.||||..|  .  ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------RKEYHIIMDLCEGGD-LRQFIDKRQRMQTSLEEELIWLYMGQILLALAYLHC--P--FKSGIQQHGR--IIHRDIKPANIFIKGSNT----
          ....|.|..|.||. | ...            ...   . .| ....|||   |   .          |||||.|..||...  .|    
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCT-------KPPIIHRDLKSKNILVDENWTNVSN

----------LIVGDLGICKDIGRHSSTDA--------------------KIGTPAYMAPEVLMNVKQ--------------GYNEKSDIWSLGLIVYEL
          . ..|.|..... ....  .                    ..|||..||||||..  .               |.||.|..| |.. .|.
YMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEI

CT
.|
LT
Kinase GL50803_8350.AA NEK2 11-155 37 4.9e-35 115.33 In-house 1-157 (319) Show / Hide 
Range on Protein: 11-155
Range on HMM: 1-157/319
Sequence Identity: 37% (59 aa)

YEILDVIGQGGFGKVYKVRYIPTEALYAYKLISYANETS-EVQGLIESEIKLTRHLSHPNIIKFHHVYHSEERKEYHIIMDLCEGGDLRQFIDKRQRMQT
||.| .||.| ||...||| ...  . . | | | . .. | | |. ||. . | | ||||... .    .. .   |.|  |||||| | | |     .
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLV-SECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQ

SLEEELIWLYMGQILLALAYLHC------------PFKSGIQQHGRIIHRDIKPANIF
 .||| ||  | |...||   |               |  |   . |.||||||||||
YMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIF
Kinase GL50803_8350.AA TyrKc 11-279 19 1.2e-16 46.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 11-279
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

YEILDVIGQGGFGKVYKVRYIPTEALYAYKLIS-YANETSEVQGLIESEIKLTRHL--SHPNIIKFHHVYHSEER-----KEYHIIMDLCEGGDLRQFID
 . ....| | ||.||| ...      | | .  .|      .  . .|... ..|  .||||.... |  ...|     . . |.| ....|||.... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KRQRMQTSLEEELIWLYMGQILLALAYLHCPFKSGIQQHGRIIHRDIKPANIFIKGSNTLIVGDLGICKDIGRH-------SSTDAK--IGTP-----AY
|...    |  .    .. ||    .|||           ..||||.   |. ..  .|  ..| | ..||. .       .  ..|   |.        
KHRPK---LCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

MAPEVLMNVKQG-YNEKSDIWSLGLIVYELCTFERLVSGA------TVADAIESIEYINFPIIVEG--------YSLELVEVINGMIDPNIMTRFSAHDL
||||..   . | ...|||.|| |   .|..|.             . ...|| ..  . . . .          . |. ...    . .   | .  ..
MAPECI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

LAHPRL
  | ..
--HECF
Kinase GL50803_8350.AA NEK2 183-219 56 3.7e-15 47.39 In-house 225-259 (319) Show / Hide 
Range on Protein: 183-219
Range on HMM: 225-259/319
Sequence Identity: 56% (21 aa)

IGTPAYMAPEVLMNVKQGYNEKSDIWSLGLIVYELCT
.||| || ||...  |  |||||||||.| ..||.|.
VGTPYYMSPEQMHGQK--YNEKSDIWSVGCLIYEMCA
Kinase GL50803_8350.AA Pkinase_Tyr 143-220 28 2.4e-07 25.5 Pfam 131-210 (270) Show / Hide 
Range on Protein: 143-220
Range on HMM: 131-210/270
Sequence Identity: 28% (23 aa)

RIIHRDIKPANIFIKGSNTLIVGDLGICKDI---GRH-SSTDAKIGTPAYMAPEVLMNVKQGYNEKSDIWSLGLIVYELCTF
..||||.   |. .. .|.  ..| | ..||   .    ...        ||||.... |  ...|||.|| |   .|..|.
NCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK--FTTKSDVWSFGVLMWEIFTY
Kinase GL50803_8350.AA Pkinase_Tyr 11-100 23 9.6e-07 23.46 Pfam 1-97 (270) Show / Hide 
Range on Protein: 11-100
Range on HMM: 1-97/270
Sequence Identity: 23% (23 aa)

YEILDVIGQGGFGKVYKVRYI----PTEALYAYKLISYANETSE--VQGLIESEIKLTRHL-SHPNIIKFHHVYHSEERK-EYHIIMDLCEGGDLRQF
 ... ..|.| ||.||| ..      |.   | | .      ..   . ... |.|. ..| .||||.... |  ....  .. |.| ....|||. .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY
Kinase GL50803_8350.AA NEK 239-279 25 0.0001 13.02 In-house 244-286 (286) Show / Hide 
Range on Protein: 239-279
Range on HMM: 244-286/286
Sequence Identity: 25% (11 aa)

INFPIIVEG--YSLELVEVINGMIDPNIMTRFSAHDLLAHPRL
...| | .   || .| ..|. |. ..   | |. ..|..| .
PQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_8350.AA NEK2 248-279 37 0.000193 10.73 In-house 288-319 (319) Show / Hide 
Range on Protein: 248-279
Range on HMM: 288-319/319
Sequence Identity: 37% (12 aa)

YSLELVEVINGMIDPNIMTRFSAHDLLAHPRL
|| .| |.|  ||. .  .| |   .|.||..
YSRHLNEIIHFMINVDHYHRPSIEEILQHPQI
Ank GL50803_8350.AA Ank 354-368 33 2.827394 5.25 Pfam 1-15 (33) Show / Hide 
Range on Protein: 354-368
Range on HMM: 1-15/33
Sequence Identity: 33% (5 aa)

FNHTPLMIAAEAGDL
   |||..|.. |..
DGFTPLHLACRCGHT
Ank GL50803_8350.AA Ank 385-407 47 0.000112 21.13 Pfam 1-23 (33) Show / Hide 
Range on Protein: 385-407
Range on HMM: 1-23/33
Sequence Identity: 47% (11 aa)

RGYTALMLAVEQGHMKCVKSLLG
 |.|.|.||.. ||...|| ||.
DGFTPLHLACRCGHTEVVKMLLQ
Ank GL50803_8350.AA Ank 416-436 42 0.008533 14.34 Pfam 1-21 (33) Show / Hide 
Range on Protein: 416-436
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

DGTTALIIALTRGYTDIAKLL
|| |.| .|  .|.|...|.|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_8350.AA Ank 447-472 38 0.00232 16.38 Pfam 1-26 (33) Show / Hide 
Range on Protein: 447-472
Range on HMM: 1-26/33
Sequence Identity: 38% (10 aa)

DGRTPLMIAVERHHSVLIKPLAKYSA
||.|||..|... |   .| | .. |
DGFTPLHLACRCGHTEVVKMLLQHGA
Ank GL50803_8350.AA Ank 509-529 38 0.009096 14.24 Pfam 1-21 (33) Show / Hide 
Range on Protein: 509-529
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

KGKTALMLASEQGSLALCKLL
 | |.|.||.. |..  .|.|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_8350.AA Ank 478-508 30 0.201171 9.39 Pfam 1-33 (33) Show / Hide 
Range on Protein: 478-508
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

DGTTALMIAVQLLDAVSVKALAK--AESGIATD
|| |.|..|..  ..  || | .  |.  . .|
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_8350.AA Ank 540-572 36 0.000205 20.18 Pfam 1-33 (33) Show / Hide 
Range on Protein: 540-572
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

DGTTALMIALERGYEEVVALLYRREKDICKDDG
|| |.|..| ..|..||| .|  .  |..  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD