Gene GL50803_2796 (G.lamblia)

GL50803_2796

Species: G.lamblia
Alias: GL50803_2796, GK081
External Links: GiardiaDB ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKA

Sequence

Name Sequence Type Origin Length Description Download
GL50803_2796.AA Protein None 570 None Fasta, JSON
GL50803_2796.kin_dom Protein Kinase Domain None 289 None Fasta, JSON

Protein domain

Protein domains of GL50803_2796.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PBD GL50803_2796.AA PBD 19-51 52 1e-06 25.84 Pfam 1-34 (60) Show / Hide 
Range on Protein: 19-51
Range on HMM: 1-34/60
Sequence Identity: 52% (18 aa)

SISQP-FDLKRGISVRYDPQTGKFTGLPEEWQKL
 || | .. |. . | .|.|||.|||.|.|||||
MISTPLTNFKHTMHVGWDGQTGFFTGMPPEWQKL
PBD GL50803_2796.AA PBD 20-55 44 0.000489 19.26 SMART 1-38 (38) Show / Hide 
Range on Protein: 20-55
Range on HMM: 1-38/38
Sequence Identity: 44% (17 aa)

ISQPF-DLKRGISVR-YDPQTGKFTGLPEEWQKLGLIP
|| |. . |  . |   |.|||.|||||..||.|   .
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
PBD GL50803_2796.AA PBD 148-184 35 1e-06 29.36 SMART 1-38 (38) Show / Hide 
Range on Protein: 148-184
Range on HMM: 1-38/38
Sequence Identity: 35% (14 aa)

ISRPT-GFTHKNHVT-VDPTNATRYIGLPKEWEAKLEAV
|| ||  |.|. ||  .|. . . . |||..|.. |   
ISTPTGNFKHIVHVGPWDG-QTGEFTGLPHQWQHLLKHC
PBD GL50803_2796.AA PBD 147-178 39 0.000117 19.18 Pfam 1-32 (60) Show / Hide 
Range on Protein: 147-178
Range on HMM: 1-32/60
Sequence Identity: 39% (13 aa)

FISRP-TGFTHKNHVTVDPTNATRYIGLPKEWE
 || | | |.|. ||. |. . . ..|.|.||.
MISTPLTNFKHTMHVGWDGQTGF-FTGMPPEWQ
Kinase GL50803_2796.AA STE 268-556 26 2e-86 293.4 In-house 1-359 (359) Show / Hide 
Range on Protein: 268-556
Range on HMM: 1-359/359
Sequence Identity: 26% (102 aa)

YSNPQEVGHGSSGHVYRATEIK---------------TGNVVAIKSISAINFLTDDGKKVRDIKSAEAATLM----------ALKNEVALMYLSKE-CEY
. . ...|.|..| ||.|  .|               ||...||| ..  |  . | .        |.   .           ...|. .|  ..  ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-E----N-Q-EN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPN

IVKLHKVYFSKAAK-----EFYMIMDYCNANCLTNILS-RHGYIKN------------ERVSCMIIRDILKA-LNHLHENHRIYRDLKSDNVLLNAELIN
||| .  || .  .     | ...| |... .|. |.  ..|  |.            | . . |.|.|||. |..||..|.| ||.|..|.||      
IVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------

SLAQDGAITKKKKFSLKLSDFGFAVQLN----------------TKQPTRKSVVGTPFWMAPELIRG------TEYNTKVDCWSLGIVVLELCESLPPHM
                ||.|||.. ||.                | |  |...|||| ||||| |..       .|.||.| ||||....|...  ||..
---------------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWH

EMQPLKAVFKIVTS---------------PAPSFKK-----------------PSQWTPELNDFLARCLDKDPDSRWSCAQLLE--HPWI
.|.|..| | | ..               | |...                  |..|.||..||...||.|||. |..  |||.  ||.|
DMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_2796.AA S_TKc 268-556 25 1.4e-80 274.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 268-556
Range on HMM: 1-231/231
Sequence Identity: 25% (79 aa)

YSNPQEVGHGSSGHVYRATEIKTGNVVAIKSISAINFLTDDGKKVRDIKSAEAATLMALKNEVALMYLSKECEYIVKLHKVYFSKAAKEFYMIMDYCNA-
|   ...|.|. | ||.....||| .|||| |.                         ...|....     ...||||. |. .   ...||.|.||.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGD

-NCLTNILSRHGYI-----KNERVSCMIIRDILKALNHLHENHRIYRDLKSDNVLLNAELINSLAQDGAITKKKKFSLKLSDFGFAVQLNTKQPTRKSVV
   |  .. ..|.       .| . . ... |..||...|... |.|||| .|.||.                    .|..|||.| ||       ....
LGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------------------HIKICDFGLARQL-------TTFC

GTPFWMAPELIRGTEYNT-KVDCWSLGIVVLELCESLPPHMEMQPLKAVFKIVTSPAPSFKKPSQWTPELNDFLARCLDKDPDSRWSCAQLLE-------
|||..||||..    |.. |.| ||.|... |..   ||      ....||..             .||. ||. .||.|||. |... ..|.       
GTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

HPWI
|||.
HPWF
Kinase GL50803_2796.AA Pkinase 268-556 26 1.2e-64 225.9 Pfam 1-293 (293) Show / Hide 
Range on Protein: 268-556
Range on HMM: 1-293/293
Sequence Identity: 26% (85 aa)

YSNPQEVGHGSSGHVYRATEIKTGNVVAIKSISAINFLTDDGKKVRDIKSAEAATLMALKNEVALMYLSKECEYIVKLHKVYFSKAAKEFYMIMDYCNAN
|   . .| ||.| ||......|| .||.| |.  .   .  .  | .            .|...|     ...||.|. .. .   .. ||.|.||.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL------------SEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGG

----CLTNILS--RHGYI-KNERVSCMIIRDILKALNHLHENHRIYRDLKSDNVLLN-AELINSLAQDGAITKKKKFSLKLSDFGFAVQL-NTKQPTRKS
     |  ..|  ||| .   |.. ..... ||..|...|..  |.||||..|.|..    |..             ..|..|||.| |. . ...  ..
LYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-------------CVKICDFGLAKQFDY-NNS-MTT

VVGTPFWMAPELIR-GTEYNTKVDCWSLGIVVLELCESLPPHMEM------QPLKAVFKIVTSPAPSFKKPS------------------QWTPELNDFL
..|||..||||.|| |..| .||| ||.|... |..   ||  .        ... ...|   | ..    .                   |..|. ||.
FCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI

ARCLDKDPDSRWSCAQLLEHPWI
 .||.||| .|....|.|.|||.
KWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_2796.AA STE20 439-556 43 7.6e-61 208.45 In-house 157-288 (288) Show / Hide 
Range on Protein: 439-556
Range on HMM: 157-288/288
Sequence Identity: 43% (57 aa)

KLSDFGFAVQLNT-----KQPTRKSVVGTPFWMAPELIRG-----TEYNTKVDCWSLGIVVLELCESLPPHMEMQPLKAVFKIV--TSPAPSFKK--PSQ
||.|||.. ||..     .|..|...||||.|||||.|..      .|..|.| |||||  .|. |  ||...|.|..| |.|   . | | .|.  |..
KLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHK

WTPELNDFLARCLDKDPDSRWSCAQLLEHPWI
|.||..||...||.|||. |..  |||.||.|
WSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase GL50803_2796.AA PAKA 437-556 47 9e-59 201.57 In-house 141-260 (260) Show / Hide 
Range on Protein: 437-556
Range on HMM: 141-260/260
Sequence Identity: 47% (57 aa)

SLKLSDFGFAVQLNTKQPTRKSVVGTPFWMAPELIRGTEYNTKVDCWSLGIVVLELCESLPPHMEMQPLKAVFKIVTSPAPSFKKPSQWTPELNDFLARC
| |. ||||..||. .|  |...|||| |||||.||. .|. ||| ||||| ..|. |. ||.... ||.| . | |  .| .| |  |..|..|||..|
SVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKC

LDKDPDSRWSCAQLLEHPWI
|..|.|.|.|  .||.|| .
LCVDVDRRASAQELLHHPFL
Kinase GL50803_2796.AA MST 439-556 48 1.9e-56 177.89 In-house 137-254 (254) Show / Hide 
Range on Protein: 439-556
Range on HMM: 137-254/254
Sequence Identity: 48% (57 aa)

KLSDFGFAVQLNTKQPTRKSVVGTPFWMAPELIRGTEYNTKVDCWSLGIVVLELCESLPPHMEMQPLKAVFKIVTSPAPSFKKPSQWTPELNDFLARCLD
||.||| . ||   .  | .|.|||.||||| |    |..|.| |||||  .|. |. ||  . .|  | |.| ..| |.||.|.|| .|.|||...|| 
KLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQ

KDPDSRWSCAQLLEHPWI
|.|. ||.  |||.|| |
KNPEQRWTAEQLLQHPFI
Kinase GL50803_2796.AA Ciliate-E2 268-556 19 4.4e-52 177.06 In-house 1-365 (365) Show / Hide 
Range on Protein: 268-556
Range on HMM: 1-365/365
Sequence Identity: 19% (77 aa)

YSNPQEVGHGSSGHVYRATEIKTGNVVAIKSISAINFLTD------DGKKVRDIKSAEAATLMALKNEVALM--------YLSKE--------CEYIVKL
|   .  | |. | ||... .|... .||| |   .   .      . .|   .|. .   . ..|.|  .|         . .|        . .|.|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKM

HKVYFSKAAKEFYMIMDYCNANCLTNILS-----RHGYIK-----NERVSCMIIRDILK---------------ALNHLHENH-RIYRDLKSDNVLLNAE
. .. .|  . .|..|.||. . |  ..      |.  |.     .|.  . |.. ||.               ||..||...  |.||.| .|.|.   
YECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

LINSLAQDGAITKKKKFSLKLSDFGFAVQLNTKQP-------------------------------TRKSVVGTPFWMAPELIRGTE---------YNTK
                  .|..|||.. ......                                . ....|||  |||| ..| .         |..|
------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYK

VDCWSLGIVVLELCESLPPHMEMQPLKAVFKIVTSPAPSFK----------------KPSQWTPELNDFLAR----CLDKDPDSRWS-CAQLLEHPWI
.| ||||..  |..   ||          ...      .|                 .. .|..|  |.. .    .|.|||. | .   |.|.|||.
CDIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_2796.AA PAKL 439-556 46 8.8e-51 175.03 In-house 138-256 (256) Show / Hide 
Range on Protein: 439-556
Range on HMM: 138-256/256
Sequence Identity: 46% (55 aa)

KLSDFGFAVQLNTKQP-TRKSVVGTPFWMAPELIRGTEYNTKVDCWSLGIVVLELCESLPPHMEMQPLKAVFKIVTSPAPSFKKPSQWTPELNDFLARCL
|. |||   ||..      .. .|||.||||| |  . || |.| |||||.. |. ...||| .| | .|   |   | | |..|  | |..|||||.|.
KIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCC

DKDPDSRWSCAQLLEHPWI
 |||  |||  .|| || |
VKDPEKRWSPIDLLCHPFI
Kinase GL50803_2796.AA SLK 341-556 34 5.7e-50 166.72 In-house 57-259 (259) Show / Hide 
Range on Protein: 341-556
Range on HMM: 57-259/259
Sequence Identity: 34% (76 aa)

YIVKLHKVYFSKAAKEFYMIMDYCNANCLTNILSRHGYIKNERVSCMIIRDILKALNHLHENHRIYRDLKSDNVLLNAELINSLAQDGAITKKKKFSLKL
.|||| . |.    .. .|....|.   . ||.   .    |    .. . .. |||.||.|. |.||||  |.|        ...|| .        .|
NIVKLYEAYY--YDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNIL--------MTMDGDV--------RL

SDFGFAVQLNTKQPTRKSVVGTPFWMAPELI-----RGTEYNTKVDCWSLGIVVLELCESLPPHMEMQPLKAVFKIVTSPAPSFKKPSQWTPELNDFLAR
 ||| . ..  .   | . .|||.|||||..     . . |  |.| ||||| ..|. .  ||| ||.|.. ..||  |  |  ..||.|. | .||| .
ADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKK

CLDKDPDSRWSCAQLLEHPWI
||.|||. ||. |||..|.|.
CLVKDPQNRWTTAQLMQHQWV
Kinase GL50803_2796.AA PAKB 356-556 38 2.9e-48 166.66 In-house 70-252 (252) Show / Hide 
Range on Protein: 356-556
Range on HMM: 70-252/252
Sequence Identity: 38% (77 aa)

EFYMIMDYCNANCLTNILSRHGYIKNERVSCMIIRDILKALNHLHENHRIYRDLKSDNVLLNAELINSLAQDGAITKKKKFSLKLSDFGFAVQLNTKQPT
|   .| .     || | .    .. | .   . | .|.||  ||    | || ||| .|        |..|| .        |||||||  |.    | 
ELWVVMEFMEGGALTDIVTHT-RMNEEQI-ATVCRQVLQALAYLHAQGVIHRDIKSDSIL--------LTHDGRV--------KLSDFGFCAQVSKEVPK

RKSVVGTPFWMAPELIRGTEYNTKVDCWSLGIVVLELCESLPPHMEMQPLKAVFKIVTSPAPSFKKPSQWTPELNDFLARCLDKDPDSRWSCAQLLEHPW
||| ||||.|||||.|    | |.|| ||||| |.|. .  ||    .||.|  .|  .. | .|.     |.| .|| |.| .||  ||. . ||.|| 
RKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEPPLQAMKRIRDMHPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPF

I
.
L
Kinase GL50803_2796.AA YSK 439-556 38 5.8e-47 139.23 In-house 139-257 (257) Show / Hide 
Range on Protein: 439-556
Range on HMM: 139-257/257
Sequence Identity: 38% (46 aa)

KLSDFGFAVQLNTKQPTRKSVVGTPFWMAPELIRG--TEYNTKVDCWSLGIVVLELCESLPPHMEMQPLKAVFKIVTSPAPSFKKPSQWTPELNDFLARC
|| ||| | |..  |  |   ||||.|||||.|    ..|..|.| |||||  .|.   .||. .. |... | |. .. |. .. ....  . .| . |
KLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECC

LDKDPDSRWSCAQLLEHPWI
|.|||  | |  .|| |  |
LNKDPEQRPSAKELLKHKFI
Kinase GL50803_2796.AA CAMK 273-488 18 4.9e-41 129.5 In-house 1-323 (425) Show / Hide 
Range on Protein: 273-488
Range on HMM: 1-323/425
Sequence Identity: 18% (62 aa)

EVGHGSSGHVYRATEIKTG------------NVVAIKSISAINFL------------TDDGKKVRDIKSAEAATLMALKNEVALMYLSKE------CEYI
. |.|| | |.......|.              |||| |.                  |. |. .. .  .. ..  ...|...| . ..       . |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLHKVYFSKA-----------------AKEFYMIM---DYCNAN-----CLTNILSRHG-------------YIKNERVSCMIIRDILKALNHLHENHR
.||. || ..                   |..||.|   .||        ..  | .. .                .||  . ..| |. |....|... 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IYRDLKSDNVLLNAELINS---------LAQDGAITKKKKFSLKLSDFGFAVQLNTKQ-----------------------PTRKSVVGTPFWMA-PELI
. |||| .|.||.    .|         .         ... .|..||||| ... ..                       .  | ..|||  || ||..
VHRDLKPENILLDDNNDDSDPVEHDEIFD--------WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVL

RG--------------TEYNTKVDCWSLGIV
.|              . |. |.|.||.|..
NGKGHCNMQNATDEEKPYYGPKCDMWSCGVI
Kinase GL50803_2796.AA STE20 326-419 30 2.8e-15 52.54 In-house 51-153 (288) Show / Hide 
Range on Protein: 326-419
Range on HMM: 51-153/288
Sequence Identity: 30% (32 aa)

LKNEVALMYLSKECEYIVKLHKVYFSKAA--KEFYMIMDYCNANCLTNILS---RHG------YIKNERVSCMIIRDILKALNHLHENHRIYRDLKSDNV
...|.  |  .| ...||| .  |. .     | ...|.||.. .|| |..   ..|       .. | ... | |..|..|..||.||.| ||.|.||.
IQKEISIMKQCK-HPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMKHCMKCGKNHKGHPMNEEQIAY-ICREVLQGLDYLHSNHIIHRDIKADNI

LLNAE
||. .
LLTED
Kinase GL50803_2796.AA PAKA 356-419 31 2.9e-15 50.14 In-house 72-139 (260) Show / Hide 
Range on Protein: 356-419
Range on HMM: 72-139/260
Sequence Identity: 31% (22 aa)

EFYMIMDYCNANCLTNILSRHG-----YIKNERVSCMIIRDILKALNHLHENHRIYRDLKSDNVLLNAE
| ...|.| .. ||| ...        |.. . ... ..| .|..|. .|..||| ||.||||.||...
ELWVVMEYMEGGCLTDVITQCCNIQCNYMDEGQIAY-VCRECLQGLEFIHSKHRIHRDIKSDNILLGMD
Kinase GL50803_2796.AA TyrKc 268-556 18 8.4e-14 0.48 SMART 1-280 (280) Show / Hide 
Range on Protein: 268-556
Range on HMM: 1-280/280
Sequence Identity: 18% (60 aa)

YSNPQEVGHGSSGHVYRATEIKTGNVVAIKSISAINFLTDDGKKVRDIKSAEAATLMALKNEVALMYLS-KECEYIVKLHKVYFSK-----AAKEFYMIM
 .  .. |.|  | ||..| .     ||.|.. .                     .... .|  .|    .. . ||.|. |  ..      ..  ...|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM

DYCNANCLTNILSRHGY-IKNERVSCMIIRDILKALNHLHENHRIYRDLKSDNVLLNAELINSLAQDGAITKKKKFSLKLSDFGFAVQLNTK-------Q
 |.   .| . | .|.  ....    . . .| .  ..||... | |||   |.|.....                  | |||| .  .  .       .
EYMPHGDLKDYLRKHRPKLCMKDLLSFCW-QIACGMEYLHSKNCIHRDLAARNCLVGENH----------------TVKISDFGLSRDIYDDDQQGESKD

PTRKSV-VGTP-----FWMAPELIRGTEYNTKVDCWSLGIV---VLELCESLPPHMEM--QPLKAVFKIVTSPAPSFKKPS-------QWTPELNDFLAR
  ||.   |.       ||||| |.  ...|| | || |..   .. .... .| |.    . . |.. | .     . |.         ..|. .   .
YYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQ

CLDKDPDSRWSCAQLLEHPWI
| . ||..| . ...  |  .
CWHEDPEDRPTFSEI--HECF
Kinase GL50803_2796.AA PAKA 268-299 47 6.6e-11 34.65 In-house 1-34 (260) Show / Hide 
Range on Protein: 268-299
Range on HMM: 1-34/260
Sequence Identity: 47% (16 aa)

YSNPQEVGHGSSGHVYRATEIKTGNV--VAIKSI
| . ...| |.|| ||.||.|||..   |||| .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQM
Kinase GL50803_2796.AA CAMK 519-556 31 2.9e-10 28.54 In-house 390-425 (425) Show / Hide 
Range on Protein: 519-556
Range on HMM: 390-425/425
Sequence Identity: 31% (12 aa)

FKKPSQWTPELNDFLARCLDKDPDSRWSCAQLLEHPWI
| .. . ..|  |.. ..| .||. |....| |.|||.
F-HH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_2796.AA STE20 268-300 37 1.1e-09 31.94 In-house 1-37 (288) Show / Hide 
Range on Protein: 268-300
Range on HMM: 1-37/288
Sequence Identity: 37% (14 aa)

YSNPQEVGHGSSGHVYRATEIKTGNV----VAIKSIS
| . ...|.||.| ||.|....||..    |||| ..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMN
Kinase GL50803_2796.AA Pkinase_Tyr 268-544 20 1e-08 30.13 Pfam 1-260 (270) Show / Hide 
Range on Protein: 268-544
Range on HMM: 1-260/270
Sequence Identity: 20% (60 aa)

YSNPQEVGHGSSGHVYRATEI----KTGNVVAIKSISAINFLTDDGKKVRDIKSAEAAT--LMALKNEVALMYLSKECEYIVKLHKVYFSKAAK-EFYMI
 .  .. |.|. |.||..|      .|.  ||.|..                 .|      . .. .|...|     .. ||.|. |  ..    . |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK---------------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIV

MDYCNANCLTNILSRH---GYIKNERVSCMIIRDILKALNHLHENHRIYRDLKSDNVLLNAELINSLAQDGAITKKKKFSLKLSDFGFAVQLNTKQPTRK
| |.   .| . | .|   .   .    . . ..| |....|.... | |||   |.|..                 ..  | .||| |  . ..  .  
MEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----------------NNVVKICDFGLARDI-YNDDYY-

SVVGT-----PFWMAPELIRGTEYNTKVDCWSLGIVVLELCE-SLPP-HMEMQPLKAVFKI-VTSPAPSFKKPSQWTPELNDFLARCLDKDPDSR
.....      .||||| |.  ...|| | || |..  |..     |   .| .   . .|         ..|   ..|. | . .| ..||. |
YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDR
Kinase GL50803_2796.AA YSK 388-419 50 9.8e-08 18.99 In-house 104-135 (257) Show / Hide 
Range on Protein: 388-419
Range on HMM: 104-135/257
Sequence Identity: 50% (16 aa)

IIRDILKALNHLHENHRIYRDLKSDNVLLNAE
|.| |||.|  ||..  | || |. ||||...
ILREILKGLDYLHSERKIHRDIKAANVLLSEH
Kinase GL50803_2796.AA YSK 268-299 40 1.5e-07 18.45 In-house 1-32 (257) Show / Hide 
Range on Protein: 268-299
Range on HMM: 1-32/257
Sequence Identity: 40% (13 aa)

YSNPQEVGHGSSGHVYRATEIKTGNVVAIKSI
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FTKQECIGRGSFGEVYKGIDNRTQRVVAIKII
Kinase GL50803_2796.AA MST 268-297 43 1e-06 17.09 In-house 1-30 (254) Show / Hide 
Range on Protein: 268-297
Range on HMM: 1-30/254
Sequence Identity: 43% (13 aa)

YSNPQEVGHGSSGHVYRATEIKTGNVVAIK
..     | || | ||.|. ..||..||||
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIK
Kinase GL50803_2796.AA MST 388-419 50 9e-06 14.17 In-house 102-133 (254) Show / Hide 
Range on Protein: 388-419
Range on HMM: 102-133/254
Sequence Identity: 50% (16 aa)

IIRDILKALNHLHENHRIYRDLKSDNVLLNAE
| .| |. |  || |..| ||.|. | ||| |
ILYDTLQGLQYLHDNKKIHRDIKAGNILLNHE
Kinase GL50803_2796.AA PAKB 269-297 48 0.001587 8.94 In-house 2-30 (252) Show / Hide 
Range on Protein: 269-297
Range on HMM: 2-30/252
Sequence Identity: 48% (14 aa)

SNPQEVGHGSSGHVYRATEIKTGNVVAIK
 |   .| || | |  |||. || .||.|
DNYVKIGEGSTGIVCIATEKHTGRQVAVK
Kinase GL50803_2796.AA PAKL 275-300 46 0.075186 3.1 In-house 8-33 (256) Show / Hide 
Range on Protein: 275-300
Range on HMM: 8-33/256
Sequence Identity: 46% (12 aa)

GHGSSGHVYRATEIKTGNVVAIKSIS
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GQGSYGSVYKAIHKDTNFPLAIKVIE