Gene GL50803_17622 (G.lamblia)
GL50803_17622
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_17622.AA | Protein | None | 1537 | None | Fasta, JSON |
| GL50803_17622.kin_dom | Protein Kinase Domain | None | 249 | None | Fasta, JSON |
Protein domains of GL50803_17622.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | GL50803_17622.AA | NEK | 23-124 | 23 | 8.5e-11 | 34.64 | In-house | 13-124 (286) | Show / Hide |
Range on Protein: 23-124 Range on HMM: 13-124/286 Sequence Identity: 23% (26 aa) STTYTARRKSDGKT-----VAARKFLLFLLGPTERLAVD-NEISILQKISHPNVPAYKEIRFSNDSKIMYVITAYVQ-SETLACL---ISDARERGTHIE .. | .||||||| .. | . . . |. . ||. ||... |||. .|.. . ... .. . | .|. . | ...|...| GKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFE EKTIWGFIADLL |..|| . . .. EEQIWDWFIQMC |
|||||||||
| Kinase | GL50803_17622.AA | NZAK | 57-136 | 23 | 2e-06 | 16.88 | In-house | 47-124 (329) | Show / Hide |
Range on Protein: 57-136 Range on HMM: 47-124/329 Sequence Identity: 23% (19 aa) NEISILQKISHPNVPAYKE--IRFSNDSKIMYVITAYVQSETLACLISDARERGTHIEEKTIWGFIADLLDLLQFILLPHKQ .|. || || |.|.| | |.. .| ... .. . |. .... . . . | | |||. . . ||. HETDILEKIRHFNIPRYYSACIKHAEDDNYHCIYMEWMEGGNLTQFLMNDKKQL-RFKEHRIIKMIADIAETMSYL---HKH |
|||||||||
| Kinase | GL50803_17622.AA | S_TKc | 11-271 | 10 | 4e-06 | -86.49 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 11-271 Range on HMM: 1-231/231 Sequence Identity: 10% (34 aa) YDVRHLVFRDDVSTTYTARRKSDGKTVAARKFLLFLLGPTERLAVDNEISILQKISHPNVPAYKEIRFSNDSKIMYVITAYVQS--ETLACLISDARERG |.. .. . .. | .| |..|. || . . .||.||.| |||. .... . . .|... |. .| .| . . .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG TH--IEEKTIWGFIADLLDLLQFI------------------------------LLPHKQYFADDEHIDFISLDPREIMVDKSKKLYVRSFTYARNDGPE .. . | ... ... ... |... .| . .. . | || LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL----------------------------TTFCGTPWYM---APE QIVEKTS-----------LYDCYVPGAS-FSTIEQRNLYLIGLLIYELCLLTPYNYYSPIGPWPSCPAEQVFFPLHTRELCTLCKSLLDITKKPRLGLSD . . || ... | |. ....... ..|.. . . .|. . |.. . VL-GYGKCKCDWWSCGCILYEMLC-GYPPFP---------QMQMMFKKIG--------------------------SPEAKDFIRKCLQKDPEKRPTA-E LID-------MPQI . .| . ALQDEWDIKCHPWF |
|||||||||
| Kinase | GL50803_17622.AA | MLCK | 11-72 | 28 | 5e-06 | 11.23 | In-house | 1-60 (257) | Show / Hide |
Range on Protein: 11-72 Range on HMM: 1-60/257 Sequence Identity: 28% (18 aa) YDVRHLVFRDDVSTTYTARRKSDGKTVAARKFLL-FLLGPTERLAVDNEISILQKISHPNVPA |... ...| .... .. ||.|||.|| .. |... | |||.|. . |||... YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRK---PKDKENVKNEIEIMNQLHHPNLIQ |
|||||||||
| Kinase | GL50803_17622.AA | DCAMKL | 55-70 | 62 | 4.3e-05 | 11.2 | In-house | 62-77 (279) | Show / Hide |
Range on Protein: 55-70 Range on HMM: 62-77/279 Sequence Identity: 62% (10 aa) VDNEISILQKISHPNV .|||.||.|||.||.. IDNEVSIMQKIKHPHI |
|||||||||
| Kinase | GL50803_17622.AA | CAMK1 | 52-70 | 45 | 0.000108 | 9.5 | In-house | 49-70 (276) | Show / Hide |
Range on Protein: 52-70 Range on HMM: 49-70/276 Sequence Identity: 45% (10 aa) RLAVDNEISILQK---ISHPNV . |..|||.|..| |.|||. QEALENEIEIMKKVSKIDHPNI |
|||||||||
| Kinase | GL50803_17622.AA | Ciliate-C1 | 54-70 | 44 | 0.000126 | 7.32 | In-house | 63-80 (328) | Show / Hide |
Range on Protein: 54-70 Range on HMM: 63-80/328 Sequence Identity: 44% (8 aa) AVDNEISILQKIS-HPNV ...|||..||. . |||. DHNNEIKHLQELKNHPNI |
|||||||||
| Kinase | GL50803_17622.AA | Ciliate-E2a | 26-70 | 31 | 0.000135 | 9.48 | In-house | 16-61 (275) | Show / Hide |
Range on Protein: 26-70 Range on HMM: 16-61/275 Sequence Identity: 31% (15 aa) YTARRKSDGKTVAARKFLLFLLGPTE--RLAVDNEISILQKISHPNV | |..| .|| |. || . .. . .. |||.|.....|||. YLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNI |
|||||||||
| Kinase | GL50803_17622.AA | RAD53 | 55-70 | 50 | 0.000286 | 8.05 | In-house | 51-66 (305) | Show / Hide |
Range on Protein: 55-70 Range on HMM: 51-66/305 Sequence Identity: 50% (8 aa) VDNEISILQKISHPNV | ||. ||.|..||.. VMNEVEILKKLNHPCI |
|||||||||
| Ank | GL50803_17622.AA | Ank | 466-499 | 29 | 0.003721 | 15.64 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 466-499 Range on HMM: 1-33/33 Sequence Identity: 29% (10 aa) TGETALYYALLHRNYQIADMLLNIEGVAVNDDTF |.|.| .| .. ..... |||. | || . DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD |
|||||||||
| Ank | GL50803_17622.AA | Ank | 515-529 | 33 | 16.249597 | 2.51 | Pfam | 1-15 (33) | Show / Hide |
Range on Protein: 515-529 Range on HMM: 1-15/33 Sequence Identity: 33% (5 aa) DDRTPLISAAMANDL | .||| |.. ... DGFTPLHLACRCGHT |
|||||||||
| Ank | GL50803_17622.AA | Ank | 546-566 | 42 | 0.004928 | 15.2 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 546-566 Range on HMM: 1-21/33 Sequence Identity: 42% (9 aa) QGKTALMHAIEHGHSEVACLL | |.|. |...|| ||. .| DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 608-617 | 60 | 0.788673 | 7.25 | Pfam | 1-10 (33) | Show / Hide |
Range on Protein: 608-617 Range on HMM: 1-10/33 Sequence Identity: 60% (6 aa) DGFTPLMISA ||||||.. . DGFTPLHLAC |
|||||||||
| Ank | GL50803_17622.AA | Ank | 639-665 | 25 | 0.106244 | 10.39 | Pfam | 1-26 (33) | Show / Hide |
Range on Protein: 639-665 Range on HMM: 1-26/33 Sequence Identity: 25% (7 aa) RGLTAMMVAVHCSENLDILHELVKHEA | |. ..|..| ..... .|..| | DGFTPLHLACRCG-HTEVVKMLLQHGA |
|||||||||
| Ank | GL50803_17622.AA | Ank | 671-691 | 33 | 0.851467 | 7.13 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 671-691 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) KGDTALMHAIRARKEPAVRLL |.|.|. |.| . |..| DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 702-722 | 28 | 2.379762 | 5.52 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 702-722 Range on HMM: 1-21/33 Sequence Identity: 28% (6 aa) SGKTALMRAALEGFSQAIPLL | |.|. |.. | . . .| DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 732-752 | 33 | 0.441158 | 8.16 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 732-752 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) EGKTALMHAIESGNITAAAML .| |.|. |...|.. . || DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 763-784 | 31 | 4.772069 | 4.43 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 763-784 Range on HMM: 1-22/33 Sequence Identity: 31% (7 aa) SGETALIKALRYELPAIAKLLI |.|.| | |. . ..|.|. DGFTPLHLACRCGHTEVVKMLL |
|||||||||
| Ank | GL50803_17622.AA | Ank | 856-888 | 27 | 0.003053 | 15.95 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 856-888 Range on HMM: 1-33/33 Sequence Identity: 27% (9 aa) SSLTALMIAVLVGNKQVIPFLLEEGHLVDETNQ |.|..|.. |...|. .||. | |. .. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
|||||||||
| Ank | GL50803_17622.AA | Ank | 825-855 | 30 | 2.16246 | 5.67 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 825-855 Range on HMM: 1-33/33 Sequence Identity: 30% (10 aa) DGFTELMIAVASFNMTIARKCLF--RDVSRQTK |||| |..|. . .. ... | || |.. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1171-1191 | 38 | 0.048447 | 11.62 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1171-1191 Range on HMM: 1-21/33 Sequence Identity: 38% (8 aa) SKKTALIVAADRGNTEIVRLL |.| .|. .|.||.|..| DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1202-1227 | 30 | 0.000417 | 19.07 | Pfam | 1-26 (33) | Show / Hide |
Range on Protein: 1202-1227 Range on HMM: 1-26/33 Sequence Identity: 30% (8 aa) SGWTALMRAAVHNHVDCVSILMKKEA |.|.|. |. ..|...|. |... | DGFTPLHLACRCGHTEVVKMLLQHGA |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1233-1253 | 38 | 1.233029 | 6.55 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1233-1253 Range on HMM: 1-21/33 Sequence Identity: 38% (8 aa) RSMSALMIATELGHIEVVSRL ...|..| . ||.|||. | DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1264-1284 | 42 | 0.000627 | 18.43 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1264-1284 Range on HMM: 1-21/33 Sequence Identity: 42% (9 aa) NYYTALMLAAKRGYTEIVEIL . .|.|.||...|.||.|. | DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1295-1315 | 38 | 0.001592 | 16.97 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1295-1315 Range on HMM: 1-21/33 Sequence Identity: 38% (8 aa) NGATALMYAIQNRHTSCVRIL .| |.|..|... ||..|. | DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1326-1346 | 33 | 0.000388 | 19.18 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1326-1346 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) NGWTALMMAAQNGFLDAVELL .|.|.|..|...| .. |..| DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1357-1379 | 39 | 0.000531 | 18.69 | Pfam | 1-23 (33) | Show / Hide |
Range on Protein: 1357-1379 Range on HMM: 1-23/33 Sequence Identity: 39% (9 aa) NGSTALMLAAQNKRLAAVKLLLS .| |.|.||... .. ||.||. DGFTPLHLACRCGHTEVVKMLLQ |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1388-1408 | 33 | 0.007136 | 14.62 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1388-1408 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) QGATALMMASENGSVAICQML | |.|..|...|.. ...|| DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1419-1441 | 43 | 8.8e-05 | 21.51 | Pfam | 1-23 (33) | Show / Hide |
Range on Protein: 1419-1441 Range on HMM: 1-23/33 Sequence Identity: 43% (10 aa) NGSTALMFAARAGNTEIASLLLN .| |.|. |.| |.||....||. DGFTPLHLACRCGHTEVVKMLLQ |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1450-1473 | 37 | 0.00496 | 15.19 | Pfam | 1-24 (33) | Show / Hide |
Range on Protein: 1450-1473 Range on HMM: 1-24/33 Sequence Identity: 37% (9 aa) VGHSALMLAAQAGAIEVCSLLLKK | ..|.||.. | .||...||.. DGFTPLHLACRCGHTEVVKMLLQH |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1481-1501 | 47 | 0.000236 | 19.96 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1481-1501 Range on HMM: 1-21/33 Sequence Identity: 47% (10 aa) DGTTALMMAARAGHHTIVELL || |.|..|.| ||. .|..| DGFTPLHLACRCGHTEVVKML |
|||||||||
| Ank | GL50803_17622.AA | Ank | 1512-1532 | 38 | 0.234481 | 9.15 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1512-1532 Range on HMM: 1-21/33 Sequence Identity: 38% (8 aa) DGVTARIIALSKGHAACVQLL || |. .| ..||. .|..| DGFTPLHLACRCGHTEVVKML |
|||||||||