Gene GL50803_17392 (G.lamblia)
GL50803_17392
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_17392.AA | Protein | None | 2245 | None | Fasta, JSON |
| GL50803_17392.kin_dom | Protein Kinase Domain | None | 899 | None | Fasta, JSON |
Protein domains of GL50803_17392.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | GL50803_17392.AA | CAMK | 278-343 | 21 | 1.2e-14 | 42.94 | In-house | 121-215 (425) | Show / Hide |
Range on Protein: 278-343 Range on HMM: 121-215/425 Sequence Identity: 21% (21 aa) TMNY-----DDNFVFII---EYCDGG----TLQEVV------------------RTADLKKIMILFYQVVDALCYMHFCNVVHQDIKLENIIITTD | .. |...... |||.|| | . . . . . .| |...|. |.| .|.|| |.|.||| .... T-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDN |
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| Kinase | GL50803_17392.AA | Ciliate-E2-Unclassified | 282-343 | 22 | 5.6e-13 | 41.37 | In-house | 93-180 (352) | Show / Hide |
Range on Protein: 282-343 Range on HMM: 93-180/352 Sequence Identity: 22% (20 aa) DDNFVFIIEYCDGGTLQEVVRT--------------------ADLKKIM-----ILFYQVVDALCYMHFCN-VVHQDIKLENIIITTD ..|. .. |||.||.|.. . . ... .|.|....|.|.| | ..| |||.|||... . KQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNN |
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| Kinase | GL50803_17392.AA | Ciliate-E2 | 282-340 | 25 | 9e-13 | 40.16 | In-house | 106-194 (365) | Show / Hide |
Range on Protein: 282-340 Range on HMM: 106-194/365 Sequence Identity: 25% (23 aa) DDNFVFIIEYCDGGTLQEVVR---TA-----------DLKKIMILFYQVVD---------------ALCYMHFCN-VVHQDIKLENIII |.|. .. |||.||.|.. . . ..|.| ...|... || |.| | ..| |||.|||.. DNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF |
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| Kinase | GL50803_17392.AA | LKB | 290-343 | 38 | 2.8e-12 | 32.82 | In-house | 82-140 (265) | Show / Hide |
Range on Protein: 290-343 Range on HMM: 82-140/265 Sequence Identity: 38% (23 aa) EYCDGGTLQEVVRTADLKKIMIL-----FYQVVDALCYMHFCNVVHQDIKLENIIITTD ||| .||.|| . |.. | | | .|.. |.| . ||| ||| |. .|.| EYCVCGTMQEMLDMQPCKRMPIWQAHFYFCQLCDGCEYLHSQRVVHKDIKPGNLLLTHD |
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| Kinase | GL50803_17392.AA | CAMKL | 282-343 | 25 | 4.6e-12 | 34.64 | In-house | 87-163 (297) | Show / Hide |
Range on Protein: 282-343 Range on HMM: 87-163/297 Sequence Identity: 25% (20 aa) DDN------FVFIIEYCDGGT--LQEVVRTADLKK-------IMILFYQVVDALCYMHFCNVVHQDIKLENIIITTD ... .. . |||.|| |.. .. .. .| |.|.|. |.| ...|| |||.||| .. . PEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDEN |
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| Kinase | GL50803_17392.AA | Ciliate-E2a | 282-341 | 30 | 5.9e-11 | 28.51 | In-house | 71-136 (275) | Show / Hide |
Range on Protein: 282-341 Range on HMM: 71-136/275 Sequence Identity: 30% (20 aa) DDNFVFIIEYCDGGTLQEVVRTAD---LK--KIMILFYQVV-DALCYMHFCNVVHQDIKLENIIIT ..|. .. |||.||.| . . . . .|. . | ..| ||| |..| |.|.|||... ENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFK |
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| Kinase | GL50803_17392.AA | NuaK | 283-338 | 33 | 8.5e-10 | 21.38 | In-house | 72-130 (252) | Show / Hide |
Range on Protein: 283-338 Range on HMM: 72-130/252 Sequence Identity: 33% (20 aa) DNFVFIIEYCDGGTLQEVVRT---ADLKKIMILFYQVVDALCYMHFCNVVHQDIKLENI | | ..|| || | . . . . .| |.| |. | | ...| | ||||| DKIVIVMEYASGGELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENI |
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| Kinase | GL50803_17392.AA | TSSK | 312-339 | 53 | 2.7e-09 | 26.62 | In-house | 128-155 (289) | Show / Hide |
Range on Protein: 312-339 Range on HMM: 128-155/289 Sequence Identity: 53% (15 aa) LFYQVVDALCYMHFCNVVHQDIKLENII .| | |.|. |.|..|||| |.|.|||. WFRQMVSAVKYCHSHNVVHRDLKCENIL |
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| Kinase | GL50803_17392.AA | CAMK | 68-140 | 22 | 1.7e-08 | 22.78 | In-house | 1-98 (425) | Show / Hide |
Range on Protein: 68-140 Range on HMM: 1-98/425 Sequence Identity: 22% (24 aa) TIGRGAYANVRLCHNPLTE------------QKAAMRMINRTSLRRKLLTQESADKFLWNCSRVMDFLTTAH----------PSILNLIEVMH------- |.|||... |.|| . .| || |. .|... |. | | . ||. .|. .. | .... ||.| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQN-QDY-S----NCY-KIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGN ---HP || KLDHP |
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| Kinase | GL50803_17392.AA | S_TKc | 63-432 | 11 | 2.9e-08 | -55.74 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 63-432
Range on HMM: 1-231/231
Sequence Identity: 11% (47 aa)
WIIQRTIGRGAYANVRLCHNPLTEQKAAMRMINRTSLRRKLLTQESADKFLWNCSRVMDFLTTAHPSILNLIEVMHHPIYADVCSVENSMESLIPGSTFA
. | |.||.||.. |..|.. | .. |. .|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------
GQYAVTPGSLPPWVQTILSIAQQVNLICELPCKYQSIIDQLSNAKGMLQPELVSDLQPLLHNPMALNGIAKPLTQGSELAHRRMPSAGSKLKQYSARSSQ
... . . ||.
---------------------------------------------------------------------------------EHIRREIQILKK-------
LDSNLTPRYQNTGRCTMNYDDNFVFIIEYCDG--GTLQEVVRT---------ADLKKIMILFYQVVDALCYMHFCNVVHQDIKLENIIITTDLQSNFK--
. .. . . |.. .. ||||| |.| .. . . . ..||...|| |.| ...| |.| ||| ... . |
-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKIC
-------------TP-------IPPASK--------------LLPRKVPRTTDLFFTSTSGTIGDFAVGTVQSQSSTPLASTALSSDPSHSNPIENTLRR
|| . . .| .| .. | . || .|. . |.. |..
DFGLARQLTTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG----------------------SPEAKDFIRKCLQK
DPKDRYNIPPLSL-------KLPL
||..|. . . .
DPEKRPTA-EALQDEWDIKCHPWF
|
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| Kinase | GL50803_17392.AA | Pkinase | 276-345 | 23 | 1.2e-07 | 28.18 | Pfam | 66-146 (293) | Show / Hide |
Range on Protein: 276-345 Range on HMM: 66-146/293 Sequence Identity: 23% (19 aa) RCTMNYDDNFVFIIEYCDGG----TLQEVVR-----TA--DLKKIMILFYQVVDALCYMHFCNVVHQDIKLENIIITTDLQ .... ..|. .. |||.|| | .... . . . . .||.. .| |.| ....| |.|.||| | . . YDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGH |
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| Kinase | GL50803_17392.AA | MARK | 312-340 | 55 | 1.6e-07 | 20.87 | In-house | 109-137 (262) | Show / Hide |
Range on Protein: 312-340 Range on HMM: 109-137/262 Sequence Identity: 55% (16 aa) LFYQVVDALCYMHFCNVVHQDIKLENIII .| |.| |..|.| |.|| |||.||| | IFRQIVSAVNYCHSKNIVHRDIKPENILI |
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| Kinase | GL50803_17392.AA | CAMK1 | 63-107 | 23 | 1.8e-07 | 17.7 | In-house | 1-55 (276) | Show / Hide |
Range on Protein: 63-107 Range on HMM: 1-55/276 Sequence Identity: 23% (13 aa) WIIQRTIGRGAYANVRLCHNPLT---EQKAAMRMIN-RTSLRR------KLLTQE ... .||||| . |.|| . | ... |. .|. .... ..| .| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENE |
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| Kinase | GL50803_17392.AA | CAMKL | 63-100 | 25 | 8.4e-07 | 17.58 | In-house | 1-39 (297) | Show / Hide |
Range on Protein: 63-100 Range on HMM: 1-39/297 Sequence Identity: 25% (10 aa) WIIQRTIGRGAYANVRLCHN-PLTEQKAAMRMINRTSLR ..| .|.|.|... |.|... .|..| |. .|.. .. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIW |
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| Pkinase | GL50803_17392.AA | Pkinase | 63-98 | 30 | 4.9e-05 | 18.88 | Pfam | 1-36 (293) | Show / Hide |
Range on Protein: 63-98 Range on HMM: 1-36/293 Sequence Identity: 30% (11 aa) WIIQRTIGRGAYANVRLCHNPLTEQKAAMRMINRTS . | |.||.|... |..||. |... |. |.. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRH |
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| Kinase | GL50803_17392.AA | CAMK1 | 315-338 | 45 | 0.000277 | 8.29 | In-house | 116-139 (276) | Show / Hide |
Range on Protein: 315-338 Range on HMM: 116-139/276 Sequence Identity: 45% (11 aa) QVVDALCYMHFCNVVHQDIKLENI |...|. ||| ..|| |.| ||. QILSAVEYMHSKGIVHRDLKPENL |
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| Kinase | GL50803_17392.AA | MARK | 63-88 | 38 | 0.000291 | 10.03 | In-house | 1-26 (262) | Show / Hide |
Range on Protein: 63-88 Range on HMM: 1-26/262 Sequence Identity: 38% (10 aa) WIIQRTIGRGAYANVRLCHNPLTEQK . .||| |.|| |.|... .|..| YKMLKTIGHGSYAKVKLACHKHTGRK |
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| Kinase | GL50803_17392.AA | NuaK | 63-94 | 31 | 0.002437 | 4.04 | In-house | 1-32 (252) | Show / Hide |
Range on Protein: 63-94 Range on HMM: 1-32/252 Sequence Identity: 31% (10 aa) WIIQRTIGRGAYANVRLCHNPLTEQKAAMRMI . .|.| |.| | |.| . | .. | . | YEFQKTLGKGTYGKVKLATEHSTGREVAIKSI |
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| Kinase | GL50803_17392.AA | TSSK | 63-80 | 33 | 0.003412 | 6.31 | In-house | 1-18 (289) | Show / Hide |
Range on Protein: 63-80 Range on HMM: 1-18/289 Sequence Identity: 33% (6 aa) WIIQRTIGRGAYANVRLC . ...||.|.|| |... YNVGKKIGHGSYAKVYCA |
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| Kinase | GL50803_17392.AA | Ciliate-E2-Unclassified | 63-95 | 27 | 0.004712 | 6.46 | In-house | 1-33 (352) | Show / Hide |
Range on Protein: 63-95 Range on HMM: 1-33/352 Sequence Identity: 27% (9 aa) WIIQRTIGRGAYANVRLCHNPLTEQKAAMRMIN .|...||.|... |..| . . |..|| ... YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMK |
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| Kinase | GL50803_17392.AA | Ciliate-E2 | 63-97 | 20 | 0.006485 | 5.82 | In-house | 1-34 (365) | Show / Hide |
Range on Protein: 63-97 Range on HMM: 1-34/365 Sequence Identity: 20% (7 aa) WIIQRTIGRGAYANVRLCHNPLTEQKAAMRMINRT .... ||.|... |..| . .. .. |...|. . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-Q |
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| Kinase | GL50803_17392.AA | Ciliate-E2a | 63-79 | 29 | 0.061873 | 1.51 | In-house | 1-17 (275) | Show / Hide |
Range on Protein: 63-79 Range on HMM: 1-17/275 Sequence Identity: 29% (5 aa) WIIQRTIGRGAYANVRL ... || |... |.| YKFIKKIGKGNFGSVYL |
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| Kinase | GL50803_17392.AA | LKB | 940-966 | 25 | 0.002808 | 5.65 | In-house | 239-265 (265) | Show / Hide |
Range on Protein: 940-966 Range on HMM: 239-265/265 Sequence Identity: 25% (7 aa) TDLLCGLLDEIPSHRYTLFECMYHPAV ..|. |.|. .. | .. . | || . QNLIKGMLQYDHNKRFSCHQIMHHPWF |
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| Kinase | GL50803_17392.AA | CAMKL | 941-966 | 34 | 0.003208 | 5.96 | In-house | 272-297 (297) | Show / Hide |
Range on Protein: 941-966 Range on HMM: 272-297/297 Sequence Identity: 34% (9 aa) DLLCGLLDEIPSHRYTLFECMYHPAV ||. ..| |..|.|. . | || . DLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | GL50803_17392.AA | CAMK | 941-966 | 34 | 0.011186 | 3.65 | In-house | 400-425 (425) | Show / Hide |
Range on Protein: 941-966 Range on HMM: 400-425/425 Sequence Identity: 34% (9 aa) DLLCGLLDEIPSHRYTLFECMYHPAV ||....| |..|.|. .|. || . DLIRKMLQVDPEKRMTIEQCLNHPWM |
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| Kinase | GL50803_17392.AA | CAMK1 | 941-966 | 34 | 0.07403 | 1.11 | In-house | 251-276 (276) | Show / Hide |
Range on Protein: 941-966 Range on HMM: 251-276/276 Sequence Identity: 34% (9 aa) DLLCGLLDEIPSHRYTLFECMYHPAV |.....|. |. ||| .| || . DFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | GL50803_17392.AA | MARK | 941-966 | 38 | 0.101172 | 1.6 | In-house | 237-262 (262) | Show / Hide |
Range on Protein: 941-966 Range on HMM: 237-262/262 Sequence Identity: 38% (10 aa) DLLCGLLDEIPSHRYTLFECMYHPAV .|.. || |. | |. |.| || . NLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | GL50803_17392.AA | Pkinase | 941-966 | 26 | 8.630931 | 0.34 | Pfam | 268-293 (293) | Show / Hide |
Range on Protein: 941-966 Range on HMM: 268-293/293 Sequence Identity: 26% (7 aa) DLLCGLLDEIPSHRYTLFECMYHPAV |.....|. |. |.| ... || . DFIKWCLCKDPKKRPTAEQILQHPWF |
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